Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with tacrolimus
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Fonseca ACRG et al. | Calcineurin is an important factor involved in glucose uptake in human adipocytes. | 2018 | Mol. Cell. Biochem. | pmid:29380240 |
Vandenbussche C et al. | Tacrolimus-induced nephrotoxicity in mice is associated with microRNA deregulation. | 2018 | Arch. Toxicol. | pmid:29362864 |
Li P et al. | Risk factors for BK virus infection in living-donor renal transplant recipients: a single-center study from China. | 2018 | Ren Fail | pmid:30052479 |
Chung YW et al. | Tacrolimus-Induced Apoptosis is Mediated by Endoplasmic Reticulum-derived Calcium-dependent Caspases-3,-12 in Jurkat Cells. | 2018 | Transplant. Proc. | pmid:29731088 |
Youssef A et al. | Angiolymphoid hyperplasia with eosinophilia: a case report. | 2018 | J Med Case Rep | pmid:29606120 |
Konma J et al. | Efficacy and safety of combination therapy with prednisolone and oral tacrolimus for progressive interstitial pneumonia with systemic sclerosis: A retrospective study. | 2018 | Mod Rheumatol | pmid:29442534 |
Ohara M et al. | Myasthenia Gravis Complicated with Peripheral T-cell Lymphoma, Not Otherwise Specified (PTCL-NOS), Following Thymectomy and Longstanding Tacrolimus Therapy. | 2018 | Intern. Med. | pmid:29269644 |
Kojima CA et al. | Sirolimus Associated with Tacrolimus at Low Doses in Elderly Kidney Transplant Patients: A Prospective Randomized Controlled Trial. | 2018 | Exp Clin Transplant | pmid:28836934 |
Mithani Z et al. | De Novo Donor-Specific Antibody Formation in Tacrolimus-Based, Mycophenolate Versus Mammalian Target of Rapamycin Immunosuppressive Regimens. | 2018 | Exp Clin Transplant | pmid:28332959 |
Krogstad V et al. | Determination of Tacrolimus Concentration and Protein Expression of P-Glycoprotein in Single Human Renal Core Biopsies. | 2018 | Ther Drug Monit | pmid:29578937 |