tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (2)
- Am. J. Physiol. Renal Physiol. (1)
- Drug Metab. Dispos. (1)
- Others (1)
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Morello RJ et al. | Remote ischemic preconditioning and tacrolimus in the fetal small bowel transplant in mice. | 2016 | Acta Cir Bras | pmid:27828601 |
| Anderson K et al. | A retrospective analysis of pediatric patients with lichen sclerosus treated with a standard protocol of class I topical corticosteroid and topical calcineurin inhibitor. | 2016 | J Dermatolog Treat | pmid:26138407 |
| Lee SG et al. | Enhanced topical delivery of tacrolimus by a carbomer hydrogel formulation with transcutol P. | 2016 | Drug Dev Ind Pharm | pmid:26925849 |
| Koura-Nishiura A et al. | Clearance of atypical facial necrobiosis lipoidica with tacrolimus ointment. | 2016 | J Eur Acad Dermatol Venereol | pmid:25353715 |
| Lee SH et al. | Low-dose mycophenolate mofetil in tablet form or capsule form combined with tacrolimus in the early period after kidney transplantation: a prospective randomized trial
. | 2016 | Clin. Nephrol. | pmid:27781419 |
| Cortes M et al. | The use of temporary portocaval shunt as a technical aid in auxiliary orthotopic liver transplantation. | 2016 | Liver Transpl. | pmid:27357622 |
| Nascimento J and Machado S | Pediatric-onset necrobiosis lipoidica. | 2016 | Pediatr Int | pmid:26865027 |
| Ueno KI et al. | Advantage of administering tacrolimus for improving prognosis of patients with polymyositis and dermatomyositis. | 2016 | Int J Rheum Dis | pmid:27457756 |
| Barreto P et al. | Conversion From Twice-Daily to Once-Daily Tacrolimus in Stable Kidney Graft Recipients. | 2016 | Transplant. Proc. | pmid:27742278 |
| Robinson CL et al. | Posaconazole in lung transplant recipients: use, tolerability, and efficacy. | 2016 | Transpl Infect Dis | pmid:26781986 |
| Ishida H et al. | A Prospective Randomized, Comparative Trial of High-Dose Mizoribine Versus Mycophenolate Mofetil in Combination With Tacrolimus and Basiliximab for Living Donor Renal Transplant: A Multicenter Trial. | 2016 | Exp Clin Transplant | pmid:27733107 |
| Tsunashima D et al. | Preparation of extended release solid dispersion formulations of tacrolimus using ethylcellulose and hydroxypropylmethylcellulose by solvent evaporation method. | 2016 | J. Pharm. Pharmacol. | pmid:26773717 |
| Bogossian H et al. | Expression of NO Synthase Under Medication with Cyclosporine A, Mycophenolate Mofetil, and Tacrolimus during Development of Transplant Vasculopathy on Rat Cardiac Allograft. | 2016 | Cardiovasc Ther | pmid:26924260 |
| RodrÃguez-Lago I et al. | Previous exposure to biologics and C-reactive protein are associated with the response to tacrolimus in inflammatory bowel disease. | 2016 | Rev Esp Enferm Dig | pmid:27604685 |
| Rostaing L et al. | Novel Once-Daily Extended-Release Tacrolimus Versus Twice-Daily Tacrolimus in De Novo Kidney Transplant Recipients: Two-Year Results of Phase 3, Double-Blind, Randomized Trial. | 2016 | Am. J. Kidney Dis. | pmid:26717860 |
| Shuker N et al. | A Randomized Controlled Trial Comparing the Efficacy of Cyp3a5 Genotype-Based With Body-Weight-Based Tacrolimus Dosing After Living Donor Kidney Transplantation. | 2016 | Am. J. Transplant. | pmid:26714287 |
| Spain L et al. | Management of toxicities of immune checkpoint inhibitors. | 2016 | Cancer Treat. Rev. | pmid:26874776 |
| Kronbichler A et al. | Moderator's view: The use of calcineurin inhibitors in the treatment of lupus nephritis. | 2016 | Nephrol. Dial. Transplant. | pmid:27591329 |
| Juvvadi PR et al. | Novel motif in calcineurin catalytic subunit is required for septal localization of calcineurin in Aspergillus fumigatus. | 2016 | FEBS Lett. | pmid:26864964 |
| Ocampo-Garza J et al. | Acquired Hyperpigmentation and Cicatricial Alopecia. | 2016 | Am. J. Med. Sci. | pmid:27524226 |
| Solomon A | Allergic manifestations of contact lens wearing. | 2016 | Curr Opin Allergy Clin Immunol | pmid:27518840 |
| Navarro-Villarán E et al. | Differential Antitumoral Properties and Renal-Associated Tissue Damage Induced by Tacrolimus and Mammalian Target of Rapamycin Inhibitors in Hepatocarcinoma: In Vitro and In Vivo Studies. | 2016 | PLoS ONE | pmid:27518575 |
| Hirsch HH et al. | BK Polyomavirus Replication in Renal Tubular Epithelial Cells Is Inhibited by Sirolimus, but Activated by Tacrolimus Through a Pathway Involving FKBP-12. | 2016 | Am. J. Transplant. | pmid:26639422 |
| Cassuto E et al. | Adherence to and Acceptance of Once-Daily Tacrolimus After Kidney and Liver Transplant: Results From OSIRIS, a French Observational Study. | 2016 | Transplantation | pmid:27653227 |
| Griffin SP and Nelson JE | Impact of a Clinical Solid Organ Transplant Pharmacist on Tacrolimus Nephrotoxicity, Therapeutic Drug Monitoring, and Institutional Revenue Generation in Adult Kidney Transplant Recipients. | 2016 | Prog Transplant | pmid:27628498 |
| Saliba F et al. | Corticosteroid-Sparing and Optimization of Mycophenolic Acid Exposure in Liver Transplant Recipients Receiving Mycophenolate Mofetil and Tacrolimus: A Randomized, Multicenter Study. | 2016 | Transplantation | pmid:27454919 |
| Liu XX et al. | Limited Sampling Strategy for the Estimation of Tacrolimus Area Under the Concentration-Time Curve in Chinese Adult Liver Transplant Patients. | 2016 | Pharmacology | pmid:27449772 |
| Butts AR et al. | Factors associated with optimized tacrolimus dosing in hematopoietic stem cell transplantation. | 2016 | J Oncol Pharm Pract | pmid:25802301 |
| Zhao CY et al. | External evaluation of published population pharmacokinetic models of tacrolimus in adult renal transplant recipients. | 2016 | Br J Clin Pharmacol | pmid:26574188 |
| Zhang X et al. | The effect of calcineurin inhibitors in the induction and maintenance treatment of lupus nephritis: a systematic review and meta-analysis. | 2016 | Int Urol Nephrol | pmid:26781720 |
| Grönhagen CM and Tey HL | Meralgia paresthetica successfully treated with topical 0.1% tacrolimus: a case report. | 2016 | Int. J. Dermatol. | pmid:26518996 |
| Vadcharavivad S et al. | Validation of a 2-Point Limited Sampling Strategy to Predict the Tacrolimus Area-Under-the-12-Hour-Curve in Kidney Transplant Recipients. | 2016 | Ther Drug Monit | pmid:27328329 |
| Ayyala RS et al. | Imaging findings in a child with calcineurin inhibitor-induced pain syndrome after bone marrow transplant for beta thalassemia major. | 2016 | Pediatr Radiol | pmid:27324395 |
| Luo X et al. | Prediction of tacrolimus metabolism and dosage requirements based on CYP3A4 phenotype and CYP3A5(*)3 genotype in Chinese renal transplant recipients. | 2016 | Acta Pharmacol. Sin. | pmid:26924289 |
| Raja R et al. | A prospective study of collapsing focal segmental glomerulosclerosis. | 2016 | Ren Fail | pmid:27266801 |
| De Meyer M et al. | Pharmacogenetic-based strategy using de novo tacrolimus once daily after kidney transplantation: prospective pilot study. | 2016 | Pharmacogenomics | pmid:27266721 |
| Wilkes SR et al. | How Clinically Relevant Are Treatment Comparisons of Topical Calcineurin Inhibitor Trials for Atopic Eczema? | 2016 | J. Invest. Dermatol. | pmid:27265005 |
| Miura M et al. | Inter-laboratory Variability of Current Immunoassay Methods for Tacrolimus among Japanese Hospitals. | 2016 | Biol. Pharm. Bull. | pmid:27263473 |
| Bagherani N | Comparison of pimecrolimus with clobetasol propionate in the treatment of localized vitiligo. | 2016 | Dermatol Ther | pmid:26445411 |
| Gaynor JJ et al. | Lower tacrolimus trough levels are associated with subsequently higher acute rejection risk during the first 12 months after kidney transplantation. | 2016 | Transpl. Int. | pmid:26442829 |
| Ahmad M et al. | Effectiveness of minocycline and FK506 alone and in combination on enhanced behavioral and biochemical recovery from spinal cord injury in rats. | 2016 | Pharmacol. Biochem. Behav. | pmid:27106204 |
| Ha DH et al. | Effects of tacrolimus on morphology, proliferation and differentiation of mesenchymal stem cells derived from gingiva tissue. | 2016 | Mol Med Rep | pmid:27177273 |
| Jin J et al. | Klotho Deficiency Aggravates Tacrolimus-Induced Renal Injury via the Phosphatidylinositol 3-Kinase-Akt-Forkhead Box Protein O Pathway. | 2016 | Am. J. Nephrol. | pmid:27174564 |
| Bruns K et al. | Quantitative determination of four immunosuppressants by high resolution mass spectrometry (HRMS). | 2016 | Clin. Chem. Lab. Med. | pmid:26641969 |
| Zamorano-Leon JJ et al. | New strategy of tacrolimus administration in animal model based on tacrolimus-loaded microspheres. | 2016 | Transpl. Immunol. | pmid:27102446 |
| Dasgupta A et al. | Analytical Performance Evaluation of a New Cobas Tacrolimus Assay on Cobas e411 Analyzer: Comparison of Values Obtained by the CMIA Tacrolimus Assay and a Liquid Chromatography Combined with Tandem Mass Spectrometric Method. | 2016 | Ann. Clin. Lab. Sci. | pmid:27098629 |
| Watanabe H et al. | The efficacy of add-on tacrolimus for minor flare in patients with systemic lupus erythematosus: a retrospective study. | 2016 | Lupus | pmid:26296361 |
| Krejci K et al. | Clinical experience of conversion from cyclosporine to tacrolimus prolonged-release in stabilized kidney transplant patients. | 2016 | Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub | pmid:27174195 |
| Tang JT et al. | Pharmacogenetic aspects of the use of tacrolimus in renal transplantation: recent developments and ethnic considerations. | 2016 | Expert Opin Drug Metab Toxicol | pmid:27010623 |
| Wakamatsu A et al. | Role of calcineurin (CN) in kidney glomerular podocyte: CN inhibitor ameliorated proteinuria by inhibiting the redistribution of CN at the slit diaphragm. | 2016 | Physiol Rep | pmid:27009276 |