tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Gold BG | FK506 and the role of the immunophilin FKBP-52 in nerve regeneration. | 1999 | Drug Metab. Rev. | pmid:10461545 |
| Morris-Stiff GJ et al. | Conversion from cyclosporin (Neoral) to tacrolimus (Prograf) in renal allograft recipients with chronic graft nephropathy: results of an observational study. | 1999 | Transpl. Int. | pmid:10460877 |
| Burke GA et al. | The role of early renal biopsy in cyclosporin induced thrombotic microangiopathy. | 1999 | Pediatr. Nephrol. | pmid:10460501 |
| Drachenberg CB et al. | Islet cell damage associated with tacrolimus and cyclosporine: morphological features in pancreas allograft biopsies and clinical correlation. | 1999 | Transplantation | pmid:10459544 |
| Van Gelder RN and Kaplan HJ | Immunosuppression in uveitis therapy. | 1999 | Springer Semin. Immunopathol. | pmid:10457590 |
| Hachida M et al. | Combined use of deoxyspergualin and FK 506 for temporary circulatory assist. | 1999 | Transplant. Proc. | pmid:10455968 |
| Kobashigawa JA | Postoperative management following heart transplantation. | 1999 | Transplant. Proc. | pmid:10455966 |
| Jiang H and Kobayashi M | Differences between cyclosporin A and tacrolimus in organ transplantation. | 1999 | Transplant. Proc. | pmid:10455942 |
| Miura S et al. | The beneficial effects of FK 506 on living-related renal transplantation in presensitized recipients. | 1999 | Transplant. Proc. | pmid:10455940 |
| Jones JW et al. | Long-term survival of an extremity composite tissue allograft with FK506-mycophenolate mofetil therapy. | 1999 | Surgery | pmid:10455910 |
| Penson MG et al. | Tacrolimus-based triple-drug immunosuppression minimizes serum lipid elevations in pediatric cardiac transplant recipients. | 1999 | J. Heart Lung Transplant. | pmid:10452348 |
| Armstrong HM et al. | Potent immunosuppressive C32-O-arylethyl ether derivatives of ascomycin with reduced toxicity. | 1999 | Bioorg. Med. Chem. Lett. | pmid:10450987 |
| Goulet MT et al. | C32-O-phenalkyl ether derivatives of the immunosuppressant ascomycin: a tether length study. | 1999 | Bioorg. Med. Chem. Lett. | pmid:10450986 |
| Volbracht C et al. | ATP controls neuronal apoptosis triggered by microtubule breakdown or potassium deprivation. | 1999 | Mol. Med. | pmid:10449809 |
| Uchiyama H et al. | Approach to withdrawal from tacrolimus in a fully allogeneic murine skin graft model. | 1999 | Immunology | pmid:10447745 |
| Kur F et al. | Tacrolimus (FK506) as primary immunosuppressant after lung transplantation. | 1999 | Thorac Cardiovasc Surg | pmid:10443520 |
| Magee CC et al. | Nocardial infection in a renal transplant recipient on tacrolimus and mycophenolate mofetil. | 1999 | Clin. Nephrol. | pmid:10442495 |
| Moxey-Mims MM | Increased incidence of insulin-dependent diabetes mellitus in pediatric renal transplant patients receiving tacrolimus (FK506) | 1999 | Transplantation | pmid:10440413 |
| Sheikh AM et al. | Concomitant human immunodeficiency virus protease inhibitor therapy markedly reduces tacrolimus metabolism and increases blood levels. | 1999 | Transplantation | pmid:10440408 |
| Tsuji Y et al. | Effects of cyclosporin A, FK506 and steroid hormones on hair growth. | 1999 | Exp. Dermatol. | pmid:10439282 |
| Harikrishnan P and Harden PN | Tacrolimus can resolve cyclosporin-induced gingival hyperplasia. | 1999 | Nephrol. Dial. Transplant. | pmid:10435907 |
| Briggs WA et al. | Lymphocyte suppression by rolipram with other immunosuppressive drugs. | 1999 | J Clin Pharmacol | pmid:10434230 |
| Shinkura N et al. | Autoantibodies to FK506 binding protein 12 (FKBP12) in autoimmune diseases. | 1999 | Autoimmunity | pmid:10433096 |
| Pollock R and Rivera VM | Regulation of gene expression with synthetic dimerizers. | 1999 | Meth. Enzymol. | pmid:10432459 |
| Levy GA | Neoral/cyclosporine-based immunosuppression. | 1999 | Liver Transpl Surg | pmid:10431016 |
| Soccal PM et al. | Improvement of drug-induced chronic renal failure in lung transplantation. | 1999 | Transplantation | pmid:10428288 |
| Reichenspurner H et al. | Optimization of the immunosuppressive protocol after lung transplantation. | 1999 | Transplantation | pmid:10428269 |
| Kahan BD | An immunosuppressive triumvirate to minimize renal injuries associated with calcineurin antagonist therapy. | 1999 | Transplantation | pmid:10428260 |
| Jamieson NV | Adult small intestinal transplantation in Europe. | 1999 Apr-Jun | Acta Gastroenterol. Belg. | pmid:10427790 |
| Pirenne J | Contribution of large animal models to the development of clinical intestinal transplantation. | 1999 Apr-Jun | Acta Gastroenterol. Belg. | pmid:10427786 |
| Kato K et al. | Modulation of long-term potentiation induction in the hippocampus by N-methyl-D-aspartate-mediated presynaptic inhibition. | 1999 | Neuroscience | pmid:10426482 |
| Becker JW et al. | 32-Indolyl ether derivatives of ascomycin: three-dimensional structures of complexes with FK506-binding protein. | 1999 | J. Med. Chem. | pmid:10425089 |
| Dunn SE et al. | Calcineurin is required for skeletal muscle hypertrophy. | 1999 | J. Biol. Chem. | pmid:10419511 |
| Dalvit C et al. | Use of organic solvents and small molecules for locating binding sites on proteins in solutions. | 1999 | J. Biomol. NMR | pmid:10419292 |
| Remitz A et al. | Tacrolimus ointment improves psoriasis in a microplaque assay. | 1999 | Br. J. Dermatol. | pmid:10417522 |
| Mrowietz U | Macrolide immunosuppressants. | 1999 Jul-Aug | Eur J Dermatol | pmid:10417434 |
| Min DI et al. | Sudden hearing loss associated with tacrolimus in a kidney-pancreas allograft recipient. | 1999 | Pharmacotherapy | pmid:10417040 |
| Finn WF | FK506 nephrotoxicity. | 1999 May-Jul | Ren Fail | pmid:10416209 |
| Kuroda S et al. | The immunosuppressants cyclosporin A and FK506 equally ameliorate brain damage due to 30-min middle cerebral artery occlusion in hyperglycemic rats. | 1999 | Brain Res. | pmid:10415369 |
| Bavetta S et al. | The effects of FK506 on dorsal column axons following spinal cord injury in adult rats: neuroprotection and local regeneration. | 1999 | Exp. Neurol. | pmid:10415144 |
| Przepiorka D et al. | Tacrolimus for prevention of graft-versus-host disease after mismatched unrelated donor cord blood transplantation. | 1999 | Bone Marrow Transplant. | pmid:10414918 |
| Varghese Z et al. | Calcineurin inhibitors enhance low-density lipoprotein oxidation in transplant patients. | 1999 | Kidney Int. Suppl. | pmid:10412758 |
| Muegge I et al. | Evaluation of PMF scoring in docking weak ligands to the FK506 binding protein. | 1999 | J. Med. Chem. | pmid:10411471 |
| Rhew JH et al. | Induction of fibronectin gene expression by inhibitors of protein phosphatase type 2B in normal and transformed fibroblasts. | 1999 | Exp. Mol. Med. | pmid:10410305 |
| Hebert MF and Lam AY | Diltiazem increases tacrolimus concentrations. | 1999 | Ann Pharmacother | pmid:10410178 |
| Kaibori M et al. | Immunosuppressant FK506 inhibits inducible nitric oxide synthase gene expression at a step of NF-kappaB activation in rat hepatocytes. | 1999 | J. Hepatol. | pmid:10406194 |
| Banerjee C et al. | Ca2+ and calmodulin-dependent protein phosphatase from Leishmania donovani. | 1999 | Parasitology | pmid:10406035 |
| Timmermann W et al. | Videomicroscopic imaging of graft mucosa for monitoring immunosuppressive therapy after small intestinal transplantation in rats. | 1999 | Transplantation | pmid:10401762 |
| Tada H et al. | Role of diltiazem on tacrolimus pharmacokinetics in tacrolimus-induced nephrotoxic rats. | 1999 | Pharmacol. Toxicol. | pmid:10401724 |
| Katayama Y | [Current tendency in treatment for acute ischemic stroke]. | 1999 | Nippon Ika Daigaku Zasshi | pmid:10401232 |