tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (2)
- Am. J. Physiol. Renal Physiol. (1)
- Drug Metab. Dispos. (1)
- Others (1)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Zhang S et al. | Effect of voriconazole and other azole antifungal agents on CYP3A activity and metabolism of tacrolimus in human liver microsomes. | 2012 | Xenobiotica | pmid:22106961 |
| Jeong H and Chiou WL | Role of P-glycoprotein in the hepatic metabolism of tacrolimus. | 2006 | Xenobiotica | pmid:16507509 |
| Gupta AS et al. | Pyoderma Gangrenosum of the Scalp: A Rare Clinical Variant. | 2018 | Wounds | pmid:29481333 |
| Kiyama T et al. | Tacrolimus enhances colon anastomotic healing in rats. | 2002 Sep-Oct | Wound Repair Regen | pmid:12406167 |
| Zhou J et al. | Conversion to sirolimus immunosuppression in liver transplantation recipients with hepatocellular carcinoma: Report of an initial experience. | 2006 | World J. Gastroenterol. | pmid:16718799 |
| Schumacher G et al. | Sirolimus inhibits growth of human hepatoma cells alone or combined with tacrolimus, while tacrolimus promotes cell growth. | 2005 | World J. Gastroenterol. | pmid:15770715 |
| Meier J and Sturm A | Current treatment of ulcerative colitis. | 2011 | World J. Gastroenterol. | pmid:21912469 |
| Akamatsu N et al. | Late-onset acute rejection after living donor liver transplantation. | 2006 | World J. Gastroenterol. | pmid:17075982 |
| Higashi H et al. | First successful perinatal management of pregnancy after ABO-incompatible liver transplantation. | 2017 | World J. Gastroenterol. | pmid:28210092 |
| Shao ZY et al. | Prophylaxis of chronic kidney disease after liver transplantation--experience from west China. | 2012 | World J. Gastroenterol. | pmid:22408361 |