tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| TuÄŸcu M et al. | Tacrolimus-Induced Diabetic Ketoacidosis and Effect of Switching to Everolimus: A Case Report. | 2015 | Transplant. Proc. | pmid:26093759 |
| Aktürk S et al. | Pregnancy After Kidney Transplantation: Outcomes, Tacrolimus Doses, and Trough Levels. | 2015 | Transplant. Proc. | pmid:26093738 |
| Rahman S et al. | Nordihydroguiaretic acid attenuates skin tumorigenesis in Swiss albino mice with the condition of topical co-administration of an immunosuppressant. | 2015 | Chem. Biol. Interact. | pmid:25770929 |
| Rossetto AM et al. | The full electron structure of the FKBP12/FK506 complex. | 2015 | J. Biomol. Struct. Dyn. | pmid:24471694 |
| Li DW et al. | Risk factors for new onset diabetes mellitus after liver transplantation: A meta-analysis. | 2015 | World J. Gastroenterol. | pmid:26034369 |
| Ma R et al. | FK506 ameliorates podocyte injury in type 2 diabetic nephropathy by down-regulating TRPC6 and NFAT expression. | 2015 | Int J Clin Exp Pathol | pmid:26823720 |
| Liu Z et al. | Multitarget therapy for induction treatment of lupus nephritis: a randomized trial. | 2015 | Ann. Intern. Med. | pmid:25383558 |
| Kawaoka T et al. | Two patients treated with simeprevir plus pegylated-interferon and ribavirin triple therapy for recurrent hepatitis C after living donor liver transplantation: case report. | 2015 | Transplant. Proc. | pmid:25891736 |
| Kim YT et al. | Co-treatment effect of pulsed electromagnetic field (PEMF) with human dental pulp stromal cells and FK506 on the regeneration of crush injured rat sciatic nerve. | 2015 | Int. J. Neurosci. | pmid:25271799 |
| Kogiso T et al. | Mycophenolate mofetil may induce prolonged severe anemia during pegylated-interferon/ribavirin/simeprevir therapy in liver transplant recipients. | 2015 | Clin J Gastroenterol | pmid:25963122 |
| Bruckmueller H et al. | Which Genetic Determinants Should be Considered for Tacrolimus Dose Optimization in Kidney Transplantation? A Combined Analysis of Genes Affecting the CYP3A Locus. | 2015 | Ther Drug Monit | pmid:25271728 |
| Moscovici BK et al. | Treatment of Sjögren's syndrome dry eye using 0.03% tacrolimus eye drop: Prospective double-blind randomized study. | 2015 | Cont Lens Anterior Eye | pmid:25956572 |
| Kim D et al. | Hydrogen sulfide and hypoxia-induced changes in TASK (K2P3/9) activity and intracellular Ca(2+) concentration in rat carotid body glomus cells. | 2015 | Respir Physiol Neurobiol | pmid:25956223 |
| Tabchi S et al. | Successful treatment of Evans syndrome with Tacrolimus. | 2015 | Invest New Drugs | pmid:25209619 |
| Papadopoulos-Köhn A et al. | Daily low-dose tacrolimus is a safe and effective immunosuppressive regimen during telaprevir-based triple therapy for hepatitis C virus recurrence after liver transplant. | 2015 | Transplantation | pmid:25208324 |
| Torres-EspÃn A et al. | Immunosuppression of allogenic mesenchymal stem cells transplantation after spinal cord injury improves graft survival and beneficial outcomes. | 2015 | J. Neurotrauma | pmid:25203134 |
| Bae JM et al. | Combination therapy with 308-nm excimer laser, topical tacrolimus, and short-term systemic corticosteroids for segmental vitiligo: A retrospective study of 159 patients. | 2015 | J. Am. Acad. Dermatol. | pmid:25956660 |
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| Ennaifer R et al. | Nodular hyperplasia of the gastrointestinal tract after liver transplantation: role of immunosuppressive therapy? A case report. | 2015 | Transplant. Proc. | pmid:25891739 |
| Chung YW et al. | Transcriptional activation of nuclear-related factor 2 by FK506 in Jurkat T cells. | 2015 | Transplant. Proc. | pmid:25891728 |
| Hur J et al. | Systems pharmacological analysis of drugs inducing stevens-johnson syndrome and toxic epidermal necrolysis. | 2015 | Chem. Res. Toxicol. | pmid:25811541 |
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| Manuyakorn W et al. | In vitro cytokine changes after pediatric liver transplantation. | 2015 | Asian Pac. J. Allergy Immunol. | pmid:25840634 |
| Pidala J et al. | Prolonged sirolimus administration after allogeneic hematopoietic cell transplantation is associated with decreased risk for moderate-severe chronic graft-versus-host disease. | 2015 | Haematologica | pmid:25840599 |
| Tsai MK et al. | B cells and immunoglobulin in ABO-incompatible renal transplant patients receiving rituximab and double filtration plasmapheresis. | 2015 | J. Formos. Med. Assoc. | pmid:25839769 |
| Eaton KV et al. | Engineering macrophages to control the inflammatory response and angiogenesis. | 2015 | Exp. Cell Res. | pmid:26610863 |
| Burke MT et al. | Expression of Bcl-xL and Mcl-1 in the nonmelanoma skin cancers of renal transplant recipients. | 2015 | Am. J. Clin. Pathol. | pmid:25780003 |
| Nouchi A et al. | [Treatment of angiolymphoid hyperplasia with eosinophilia (ALHE) using topical tacrolimus: Two cases]. | 2015 | Ann Dermatol Venereol | pmid:25778634 |
| Diaz-Siso JR et al. | Initial experience of dual maintenance immunosuppression with steroid withdrawal in vascular composite tissue allotransplantation. | 2015 | Am. J. Transplant. | pmid:25777324 |
| Fujibayashi T et al. | Comparison of efficacy and safety of tacrolimus and methotrexate in combination with abatacept in patients with rheumatoid arthritis; a retrospective observational study in the TBC Registry. | 2015 | Mod Rheumatol | pmid:25775147 |
| Lehman N et al. | Left subconjunctival hemorrhage · renal dysfunction · international normalized ratio of 4.5 · Dx? | 2015 | J Fam Pract | pmid:26551480 |
| Boloori A et al. | Characterization of Remitting and Relapsing Hyperglycemia in Post-Renal-Transplant Recipients. | 2015 | PLoS ONE | pmid:26551468 |
| Lightman S et al. | Pegylated interferon-α-2b reduces corticosteroid requirement in patients with Behçet's disease with upregulation of circulating regulatory T cells and reduction of Th17. | 2015 | Ann. Rheum. Dis. | pmid:25269831 |
| Qasim W et al. | Reply to: "To target or not to target viral antigens in HBV related HCC?". | 2015 | J. Hepatol. | pmid:25711420 |
| TruneÄŒka P et al. | Renal Function in De Novo Liver Transplant Recipients Receiving Different Prolonged-Release Tacrolimus Regimens-The DIAMOND Study. | 2015 | Am. J. Transplant. | pmid:25707487 |
| Adam R et al. | Improved survival in liver transplant recipients receiving prolonged-release tacrolimus in the European Liver Transplant Registry. | 2015 | Am. J. Transplant. | pmid:25703527 |
| Li ZQ et al. | Efficacy and safety of tacrolimus vs. cyclophosphamide for idiopathic membranous nephropathy: A meta-analysis of Chinese adults. | 2015 | J. Huazhong Univ. Sci. Technol. Med. Sci. | pmid:26489612 |
| Chen QQ et al. | Kaposi's Varicelliform Eruption During Long-term Treatment of Rosacea with 0.03% Tacrolimus Ointment. | 2015 | Chin. Med. J. | pmid:26481759 |
| Badri P et al. | Pharmacokinetics and dose recommendations for cyclosporine and tacrolimus when coadministered with ABT-450, ombitasvir, and dasabuvir. | 2015 | Am. J. Transplant. | pmid:25708713 |
| Peksa GD et al. | Dosing algorithm for concomitant administration of sirolimus, tacrolimus, and an azole after allogeneic hematopoietic stem cell transplantation. | 2015 | J Oncol Pharm Pract | pmid:24938293 |
| Shengyou Y et al. | Influence of tacrolimus on podocyte injury inducted by angiotensin II. | 2015 | J Renin Angiotensin Aldosterone Syst | pmid:25650384 |
| Carenco C et al. | Tacrolimus and the risk of solid cancers after liver transplant: a dose effect relationship. | 2015 | Am. J. Transplant. | pmid:25648361 |
| Coelho R et al. | Nodular Regenerative Hyperplasia after Liver Transplantation Complicated with Inferior Vena Cava Stenosis: a Clue for Etiopathogenesis? | 2015 | J Gastrointestin Liver Dis | pmid:26405712 |
| Romanowski M et al. | Interleukin-17 gene polymorphisms in patients with post-transplant diabetes mellitus. | 2015 | Eur Rev Med Pharmacol Sci | pmid:26400516 |
| Sahin G et al. | Association between endothelial and platelet function markers and adiponectin in renal transplanted recipients on cyclosporine and tacrolimus immunosuppression based therapy. | 2015 | Nephrology (Carlton) | pmid:25650527 |
| Sato M et al. | Multifocal Fibrosclerosis with Hypertrophic Pachymeningitis and a Soft Tissue Mass around the Thoracic Vertebral Bodies: A Case Report with Review of the Literature. | 2015 | Intern. Med. | pmid:26328659 |
| Pérez-López I et al. | Koebner phenomenon in a patient with lichen sclerosus following a jellyfish sting: an exceptional morphology. | 2015 | Actas Dermosifiliogr | pmid:25597413 |
| Niioka T et al. | Capability of utilizing CYP3A5 polymorphisms to predict therapeutic dosage of tacrolimus at early stage post-renal transplantation. | 2015 | Int J Mol Sci | pmid:25594874 |
| Chittock J et al. | Comparing the Effect of a Twice-weekly Tacrolimus and Betamethasone Valerate Dose on the Subclinical Epidermal Barrier Defect in Atopic Dermatitis. | 2015 | Acta Derm. Venereol. | pmid:25594610 |
| Ling Q et al. | Donor PPARα Gene Polymorphisms Influence the Susceptibility to Glucose and Lipid Disorders in Liver Transplant Recipients: A Strobe-Compliant Observational Study. | 2015 | Medicine (Baltimore) | pmid:26334901 |
| Koch M et al. | De novo mTOR inhibitor-based immunosuppression in ABO-incompatible kidney transplantation. | 2015 | Clin Transplant | pmid:26333844 |
| Graham F et al. | Tacrolimus use in renal and cardiac pediatric transplantation: no increased risk of food allergies. | 2015 | Ann. Allergy Asthma Immunol. | pmid:26094803 |
| Velioglu A et al. | Association of BK Virus Titers With Lymphocyte Count in Renal Transplant Patients. | 2015 | Transplant. Proc. | pmid:26093733 |
| Park J et al. | Iron overload triggers mitochondrial fragmentation via calcineurin-sensitive signals in HT-22 hippocampal neuron cells. | 2015 | Toxicology | pmid:26318285 |
| Shi RZ et al. | Rapid measurement of tacrolimus in whole blood by paper spray-tandem mass spectrometry (PS-MS/MS). | 2015 | Clin. Chim. Acta | pmid:25540885 |
| Yang F et al. | A clinicopathological study of renal biopsies from 288 elderly patients: analysis based on 4,185 cases. | 2015 | Int Urol Nephrol | pmid:25539617 |
| Webb NJ et al. | Corticosteroid-free Kidney Transplantation Improves Growth: 2-Year Follow-up of the TWIST Randomized Controlled Trial. | 2015 | Transplantation | pmid:25539467 |
| Coilly A et al. | Once-daily prolonged release tacrolimus in liver transplantation: Experts' literature review and recommendations. | 2015 | Liver Transpl. | pmid:26264233 |
| Boluda ER | Pediatric small bowel transplantation. | 2015 | Curr Opin Organ Transplant | pmid:26262456 |
| Seeling W et al. | Knowledge-based immunosuppressive therapy for kidney transplant patients--from theoretical model to clinical integration. | 2015 | Stud Health Technol Inform | pmid:26262418 |
| Wardhana EA and Datau | A patient with plaque type morphea mimicking systemic lupus erythematosus. | 2015 | Acta Med Indones | pmid:26260557 |
| van Boekel GA et al. | Delayed trough level measurement with the use of prolonged-release tacrolimus. | 2015 | Transpl. Int. | pmid:25474192 |
| Li Y et al. | Differential regulation of Tregs and Th17/Th1 cells by a sirolimus-based regimen might be dependent on STAT-signaling in renal transplant recipients. | 2015 | Int. Immunopharmacol. | pmid:26186486 |
| Togashi M et al. | Effect of CYP3A5 and ABCB1 polymorphisms on the interaction between tacrolimus and itraconazole in patients with connective tissue disease. | 2015 | Eur. J. Clin. Pharmacol. | pmid:26184414 |
| Toole B et al. | Evaluation of the New Cyclosporine and Tacrolimus Automated Electrochemiluminescence Immunoassays under Field Conditions. | 2015 | Clin. Lab. | pmid:26554251 |
| Shen T et al. | Reversible sinusoidal obstruction syndrome associated with tacrolimus following liver transplantation. | 2015 | World J. Gastroenterol. | pmid:26034381 |
| Inamoto Y et al. | Tacrolimus versus Cyclosporine after Hematopoietic Cell Transplantation for Acquired Aplastic Anemia. | 2015 | Biol. Blood Marrow Transplant. | pmid:26033280 |
| Kabrine M and Laraba-Djebari F | Immunomodulatory and protective properties of tacrolimus in experimental scorpion envenomation. | 2014 Jan-Mar | Int J Immunopathol Pharmacol | pmid:24674680 |
| Wang C and Lin A | Efficacy of topical calcineurin inhibitors in psoriasis. | 2014 Jan-Feb | J Cutan Med Surg | pmid:24377467 |
| Feito-RodrÃguez M et al. | Bacterial vaginosis in the context of lichen sclerosus in a prepubertal girl. | 2014 Jan-Feb | Pediatr Dermatol | pmid:24125016 |
| Veisa G et al. | The importance of renal biopsy in the management of renal transplantation. | 2014 Apr-Jun | Rev Med Chir Soc Med Nat Iasi | pmid:25076703 |
| Backes AN et al. | Effects of tacrolimus and insulin in a liver regeneration model in growing animals with portal vein stenosis: immunohistochemical and molecular studies. | 2014 | Pediatr. Surg. Int. | pmid:24468714 |
| Tavira B et al. | [Pharmacogenetics of tacrolimus: from bench to bedside?]. | 2014 | Nefrologia | pmid:24463861 |
| Zheng X et al. | Patient with neuromyelitis optica spectrum disorder combined with Sjögren's syndrome relapse free following tacrolimus treatment. | 2014 | Intern. Med. | pmid:25318807 |
| Nevers W et al. | Safety of tacrolimus in pregnancy. | 2014 | Can Fam Physician | pmid:25316742 |
| Golubović B et al. | Total plasma protein effect on tacrolimus elimination in kidney transplant patients--population pharmacokinetic approach. | 2014 | Eur J Pharm Sci | pmid:24184751 |
| Ramachandran R et al. | Tacrolimus therapy in adult-onset steroid-resistant nephrotic syndrome due to a focal segmental glomerulosclerosis single-center experience. | 2014 | Nephrol. Dial. Transplant. | pmid:24771498 |
| Boran M et al. | Determining renal resistive and pulsatility indexes long-term after kidney transplantation in kidney transplant recipients on cyclosporine a-, tacrolimus-, or sirolimus-based regimens. | 2014 | Transplant. Proc. | pmid:24935296 |
| Yasukochi Y et al. | Reduction of serum TARC levels in atopic dermatitis by topical anti-inflammatory treatments. | 2014 | Asian Pac. J. Allergy Immunol. | pmid:25268342 |
| Zhang L et al. | Ambrisentan improves the outcome of rats with liver transplantation partially through reducing nephrotoxicity. | 2014 | Eur Rev Med Pharmacol Sci | pmid:25268107 |
| Donnadieu B et al. | Central retinal vein occlusion-associated tacrolimus after liver transplantation. | 2014 | Transplantation | pmid:25955343 |
| Wilusz M et al. | Effect of immunosuppressive therapy on the serum fatty acids of phospholipids fraction in patients after heart transplantation. | 2014 | Transplant. Proc. | pmid:25380928 |
| Noceti OM et al. | Tacrolimus pharmacodynamics and pharmacogenetics along the calcineurin pathway in human lymphocytes. | 2014 | Clin. Chem. | pmid:25142246 |
| Guy-Viterbo V et al. | Influence of donor-recipient CYP3A4/5 genotypes, age and fluconazole on tacrolimus pharmacokinetics in pediatric liver transplantation: a population approach. | 2014 | Pharmacogenomics | pmid:25141896 |
| Zhao WY et al. | Single kidneys transplanted from small pediatric donors less than 15 kilograms into pediatric recipients. | 2014 | Transplantation | pmid:25955345 |
| Elens L et al. | Impact of POR*28 on the pharmacokinetics of tacrolimus and cyclosporine A in renal transplant patients. | 2014 | Ther Drug Monit | pmid:24061445 |
| Jaksch P et al. | Alemtuzumab in lung transplantation: an open-label, randomized, prospective single center study. | 2014 | Am. J. Transplant. | pmid:25039364 |
| Bax K et al. | Rapid resolution of tacrolimus intoxication-induced AKI with a corticosteroid and phenytoin. | 2014 | Ann Pharmacother | pmid:25104567 |
| Falconer SJ et al. | Conversion from twice-daily to once-daily tacrolimus in simultaneous pancreas-kidney transplant patients. | 2014 | Transplant. Proc. | pmid:24935313 |
| Singla AK et al. | Cerulomycin Caerulomycin [corrected] A: a potent novel immunosuppressive agent. | 2014 | Transplantation | pmid:24949498 |
| Goring SM et al. | A network meta-analysis of the efficacy of belatacept, cyclosporine and tacrolimus for immunosuppression therapy in adult renal transplant recipients. | 2014 | Curr Med Res Opin | pmid:24628478 |
| Urbanowicz T et al. | Comparison of conventional tacrolimus versus prolong release formula as initial therapy in heart transplantation. | 2014 | Ann. Transplant. | pmid:24949728 |
| Shihab F et al. | Focus on mTOR inhibitors and tacrolimus in renal transplantation: pharmacokinetics, exposure-response relationships, and clinical outcomes. | 2014 | Transpl. Immunol. | pmid:24861504 |
| Lee CM et al. | Monotherapy with tacrolimus for heart and liver transplant: a case report. | 2014 | Transplant. Proc. | pmid:24767396 |
| Jin L et al. | Dipeptidyl peptidase IV inhibitor MK-0626 attenuates pancreatic islet injury in tacrolimus-induced diabetic rats. | 2014 | PLoS ONE | pmid:24959755 |
| Wan XC and Dimov V | Pharmacokinetic evaluation of topical calcineurin inhibitors for treatment of allergic conjunctivitis. | 2014 | Expert Opin Drug Metab Toxicol | pmid:24490943 |
| Philipone E et al. | Oral ulcerations as a sequela of tacrolimus and mycophenolate mofetil therapy. | 2014 | Oral Surg Oral Med Oral Pathol Oral Radiol | pmid:25457894 |
| Chen C et al. | Rapid construction of a Bacterial Artificial Chromosomal (BAC) expression vector using designer DNA fragments. | 2014 | Plasmid | pmid:25454071 |
| Olson KA et al. | Toxic tacrolimus levels after application of topical tacrolimus and use of occlusive dressings in two bone marrow transplant recipients with cutaneous graft-versus-host disease. | 2014 | Pharmacotherapy | pmid:24700567 |
| Lee CH et al. | Raised tacrolimus level and acute renal injury associated with acute gastroenteritis in a child receiving local rectal tacrolimus. | 2014 | Clin J Gastroenterol | pmid:26183743 |