tacrolimus

Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.

Cross Reference

Introduction

To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with tacrolimus?

tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with tacrolimus

MeSH term MeSH ID Detail
Mycobacterium Infections, Nontuberculous D009165 8 associated lipids
Nail Diseases D009260 2 associated lipids
Paronychia D010304 3 associated lipids
Duodenal Ulcer D004381 12 associated lipids
Dyspnea D004417 10 associated lipids
Vascular Diseases D014652 16 associated lipids
Heart Defects, Congenital D006330 20 associated lipids
Listeriosis D008088 12 associated lipids
Connective Tissue Diseases D003240 2 associated lipids
Ascites D001201 25 associated lipids
Albuminuria D000419 18 associated lipids
Anemia D000740 21 associated lipids
Osteomalacia D010018 5 associated lipids
Tremor D014202 15 associated lipids
Pemphigoid, Bullous D010391 8 associated lipids
Vasculitis D014657 14 associated lipids
Hypothermia D007035 19 associated lipids
Parkinson Disease D010300 53 associated lipids
Down Syndrome D004314 18 associated lipids
Adrenal Insufficiency D000309 3 associated lipids
Keloid D007627 12 associated lipids
Nephritis D009393 19 associated lipids
Food Hypersensitivity D005512 7 associated lipids
Respiration Disorders D012120 5 associated lipids
Thymus Neoplasms D013953 15 associated lipids
Uterine Cervical Dysplasia D002578 2 associated lipids
Facial Neoplasms D005153 3 associated lipids
Dysgammaglobulinemia D004406 3 associated lipids
Influenza, Human D007251 11 associated lipids
Immune System Diseases D007154 3 associated lipids
Headache D006261 4 associated lipids
Cystitis D003556 23 associated lipids
Sarcoma, Kaposi D012514 6 associated lipids
HIV Infections D015658 20 associated lipids
Drug Eruptions D003875 30 associated lipids
Folliculitis D005499 7 associated lipids
Blindness D001766 6 associated lipids
Oliguria D009846 2 associated lipids
Dyskinesia, Drug-Induced D004409 15 associated lipids
Dermatitis, Allergic Contact D017449 20 associated lipids
Graves Disease D006111 6 associated lipids
Peptic Ulcer Perforation D010439 3 associated lipids
Gout D006073 4 associated lipids
Papillomavirus Infections D030361 4 associated lipids
Choline Deficiency D002796 16 associated lipids
Anemia, Hemolytic, Autoimmune D000744 5 associated lipids
Biliary Fistula D001658 13 associated lipids
Glomerulonephritis, Membranoproliferative D015432 3 associated lipids
Glomerulonephritis, Membranous D015433 6 associated lipids
Renal Insufficiency D051437 8 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with tacrolimus

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with tacrolimus?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with tacrolimus?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with tacrolimus?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with tacrolimus?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with tacrolimus?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with tacrolimus

Download all related citations
Per page 10 20 50 100 | Total 15051
Authors Title Published Journal PubMed Link
Vohra S et al. Clinical and serological efficacy of topical calcineurin inhibitors in oral lichen planus: a prospective randomized controlled trial. 2016 Int. J. Dermatol. pmid:26147635
Anderson K et al. A retrospective analysis of pediatric patients with lichen sclerosus treated with a standard protocol of class I topical corticosteroid and topical calcineurin inhibitor. 2016 J Dermatolog Treat pmid:26138407
Moes DJ et al. Response: Limited sampling strategies for once daily tacrolimus exposure monitoring. 2016 Eur. J. Clin. Pharmacol. pmid:26931555
Merino D et al. Different in vitro proliferation and cytokine-production inhibition of memory T-cell subsets after calcineurin and mammalian target of rapamycin inhibitors treatment. 2016 Immunology pmid:26931075
Lee SG et al. Enhanced topical delivery of tacrolimus by a carbomer hydrogel formulation with transcutol P. 2016 Drug Dev Ind Pharm pmid:26925849
Doke T et al. Post-Transplant Membranous Nephropathy Associated with Chronic Active Antibody-Mediated Rejection and Hepatitis C Infection after Deceased Donor Renal Transplantation. 2016 Intern. Med. pmid:26875963
Rodrigues-Diez R et al. Calcineurin inhibitors cyclosporine A and tacrolimus induce vascular inflammation and endothelial activation through TLR4 signaling. 2016 Sci Rep pmid:27295076
Wen X et al. Comparison of Utilization and Clinical Outcomes for Belatacept- and Tacrolimus-Based Immunosuppression in Renal Transplant Recipients. 2016 Am. J. Transplant. pmid:27137884
Koura-Nishiura A et al. Clearance of atypical facial necrobiosis lipoidica with tacrolimus ointment. 2016 J Eur Acad Dermatol Venereol pmid:25353715
Viesselmann CW et al. Clinically Significant Drug Interaction Between Clotrimazole and Tacrolimus in Pancreas Transplant Recipients and Associated Risk of Allograft Rejection. 2016 Pharmacotherapy pmid:26877191
Ueno KI et al. Advantage of administering tacrolimus for improving prognosis of patients with polymyositis and dermatomyositis. 2016 Int J Rheum Dis pmid:27457756
Chatterjee S and Agrawal D Tacrolimus in Corticosteroid-Refractory Vernal Keratoconjunctivitis. 2016 Cornea pmid:27310883
Yan L et al. Donor ABCB1 3435 C>T genetic polymorphisms influence early renal function in kidney transplant recipients treated with tacrolimus. 2016 Pharmacogenomics pmid:26784512
Barreto P et al. Conversion From Twice-Daily to Once-Daily Tacrolimus in Stable Kidney Graft Recipients. 2016 Transplant. Proc. pmid:27742278
Wu YJ et al. Safe One-to-One Dosage Conversion From Twice-Daily to Once-Daily Tacrolimus in Long-Term Stable Recipients After Liver Transplantation. 2016 Ann. Transplant. pmid:26782179
Robinson CL et al. Posaconazole in lung transplant recipients: use, tolerability, and efficacy. 2016 Transpl Infect Dis pmid:26781986
First MR et al. Use of low-dose tacrolimus and associated hypomagnesemia in the prevention of erectile dysfunction following prostatectomy for prostate cancer. 2016 Pharmacol Rep pmid:27607363
Rodríguez-Lago I et al. Previous exposure to biologics and C-reactive protein are associated with the response to tacrolimus in inflammatory bowel disease. 2016 Rev Esp Enferm Dig pmid:27604685
Pereira M et al. Hyperacute Rejection in a Kidney Transplant With Negative Crossmatch: A Case Report. 2016 Transplant. Proc. pmid:27742303
Spain L et al. Management of toxicities of immune checkpoint inhibitors. 2016 Cancer Treat. Rev. pmid:26874776
Ocampo-Garza J et al. Acquired Hyperpigmentation and Cicatricial Alopecia. 2016 Am. J. Med. Sci. pmid:27524226
Jung HJ et al. Improved oral absorption of tacrolimus by a solid dispersion with hypromellose and sodium lauryl sulfate. 2016 Int. J. Biol. Macromol. pmid:26642839
Imai Y et al. Histone deacetylase inhibitor panobinostat induces calcineurin degradation in multiple myeloma. 2016 JCI Insight pmid:27699258
Cassuto E et al. Adherence to and Acceptance of Once-Daily Tacrolimus After Kidney and Liver Transplant: Results From OSIRIS, a French Observational Study. 2016 Transplantation pmid:27653227
Elshatory YM et al. Diagnostic and Therapeutic Challenges. 2016 Retina (Philadelphia, Pa.) pmid:26225484
Li X and Sun S Targeting the fungal calcium-calcineurin signaling network in overcoming drug resistance. 2016 Future Med Chem pmid:27463738
Butts AR et al. Factors associated with optimized tacrolimus dosing in hematopoietic stem cell transplantation. 2016 J Oncol Pharm Pract pmid:25802301
Jung H et al. FK506 regulates pigmentation by maturing the melanosome and facilitating their transfer to keratinocytes. 2016 Pigment Cell Melanoma Res pmid:26581186
Belliere J et al. Pilot conversion trial from mycophenolic acid to everolimus in ABO-incompatible kidney-transplant recipients with BK viruria and/or viremia. 2016 Transpl. Int. pmid:26575959
Hashimoto K et al. Pure red cell aplasia induced by anti-erythropoietin antibodies, well-controlled with tacrolimus. 2016 Int. J. Hematol. pmid:27338269
Grönhagen CM and Tey HL Meralgia paresthetica successfully treated with topical 0.1% tacrolimus: a case report. 2016 Int. J. Dermatol. pmid:26518996
Korobko IV and Lomonosov KM A pilot comparative study of topical latanoprost and tacrolimus in combination with narrow-band ultraviolet B phototherapy and microneedling for the treatment of nonsegmental vitiligo. 2016 Dermatol Ther pmid:27329330
Wu H et al. Developmental Neurotoxic Effects of Percutaneous Drug Delivery: Behavior and Neurochemical Studies in C57BL/6 Mice. 2016 PLoS ONE pmid:27606422
McShane AJ et al. Therapeutic drug monitoring of immunosuppressants by liquid chromatography-mass spectrometry. 2016 Clin. Chim. Acta pmid:26721314
Schneider L et al. Study of the Atopic March: Development of Atopic Comorbidities. 2016 Pediatr Dermatol pmid:27273433
Kostereva NV et al. IGF-1 and Chondroitinase ABC Augment Nerve Regeneration after Vascularized Composite Limb Allotransplantation. 2016 PLoS ONE pmid:27272754
Raja R et al. A prospective study of collapsing focal segmental glomerulosclerosis. 2016 Ren Fail pmid:27266801
Bagherani N Comparison of pimecrolimus with clobetasol propionate in the treatment of localized vitiligo. 2016 Dermatol Ther pmid:26445411
Ahmad M et al. Effectiveness of minocycline and FK506 alone and in combination on enhanced behavioral and biochemical recovery from spinal cord injury in rats. 2016 Pharmacol. Biochem. Behav. pmid:27106204
Ha DH et al. Effects of tacrolimus on morphology, proliferation and differentiation of mesenchymal stem cells derived from gingiva tissue. 2016 Mol Med Rep pmid:27177273
Kim JM et al. Conversion of once-daily extended-release tacrolimus is safe in stable liver transplant recipients: A randomized prospective study. 2016 Liver Transpl. pmid:26360125
Bican Demir A et al. Two Cases With Developing Neurologic Complications After Liver Transplant. 2016 Exp Clin Transplant pmid:26643318
Bruns K et al. Quantitative determination of four immunosuppressants by high resolution mass spectrometry (HRMS). 2016 Clin. Chem. Lab. Med. pmid:26641969
Al-Maawali AK et al. Modern Treatments and Stem Cell Therapies for Perianal Crohn's Fistulas. 2016 Can J Gastroenterol Hepatol pmid:28053967
Park OJ et al. A combination of excimer laser treatment and topical tacrolimus is more effective in treating vitiligo than either therapy alone for the initial 6 months, but not thereafter. 2016 Clin. Exp. Dermatol. pmid:26299799
Gomes RM et al. Ten-year kidney transplant survival of cyclosporine- or tacrolimus-treated patients in Brazil. 2016 Expert Rev Clin Pharmacol pmid:27181131
Shipley CA and Spivakovsky S Tacrolimus or clobetasol for treatment of oral lichen planus. 2016 Evid Based Dent pmid:27012570
Ko DH et al. Performance Evaluation of a Restored Dimension TACR Assay: An Automated Platform for Measuring the Whole Blood Tacrolimus Concentration. 2016 Clin. Lab. pmid:27012028
Tang JT et al. Pharmacogenetic aspects of the use of tacrolimus in renal transplantation: recent developments and ethnic considerations. 2016 Expert Opin Drug Metab Toxicol pmid:27010623
Tron C et al. A high performance liquid chromatography tandem mass spectrometry for the quantification of tacrolimus in human bile in liver transplant recipients. 2016 J Chromatogr A pmid:27837999