| MeSH term | MeSH ID | Detail |
|---|---|---|
| Edema | D004487 | 152 associated lipids |
| Precancerous Conditions | D011230 | 48 associated lipids |
| Postoperative Complications | D011183 | 5 associated lipids |
| Arthritis | D001168 | 41 associated lipids |
| Arthritis, Experimental | D001169 | 24 associated lipids |
| Surgical Wound Infection | D013530 | 7 associated lipids |
| Neoplasm Recurrence, Local | D009364 | 5 associated lipids |
| Osteonecrosis | D010020 | 5 associated lipids |
| Hypotension | D007022 | 41 associated lipids |
| Acute Kidney Injury | D058186 | 34 associated lipids |
tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (2)
- Am. J. Physiol. Renal Physiol. (1)
- Drug Metab. Dispos. (1)
- Others (1)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Morello RJ et al. | Remote ischemic preconditioning and tacrolimus in the fetal small bowel transplant in mice. | 2016 | Acta Cir Bras | pmid:27828601 |
| Lee YJ et al. | Acquired Bilateral Dyspigmentation on Face and Neck: Clinically Appropriate Approaches. | 2016 | J. Korean Med. Sci. | pmid:27822947 |
| Khan S et al. | Tacrolimus-loaded nanostructured lipid carriers for oral delivery - Optimization of production and characterization. | 2016 | Eur J Pharm Biopharm | pmid:27449630 |
| Lee SG et al. | Enhanced topical delivery of tacrolimus by a carbomer hydrogel formulation with transcutol P. | 2016 | Drug Dev Ind Pharm | pmid:26925849 |
| Koura-Nishiura A et al. | Clearance of atypical facial necrobiosis lipoidica with tacrolimus ointment. | 2016 | J Eur Acad Dermatol Venereol | pmid:25353715 |
| Cortes M et al. | The use of temporary portocaval shunt as a technical aid in auxiliary orthotopic liver transplantation. | 2016 | Liver Transpl. | pmid:27357622 |
| Siponen M et al. | Cathepsin K expression is increased in oral lichen planus. | 2016 | J. Oral Pathol. Med. | pmid:27152719 |
| Tomei P et al. | Everolimus-induced epithelial to mesenchymal transition (EMT) in bronchial/pulmonary cells: when the dosage does matter in transplantation. | 2016 | J. Nephrol. | pmid:27026415 |
| Chitvanich S et al. | Combination of non-ablative fractional photothermolysis and 0.1% tacrolimus ointment is efficacious for treating idiopathic guttate hypomelanosis. | 2016 | J Dermatolog Treat | pmid:26864301 |
| Ueno KI et al. | Advantage of administering tacrolimus for improving prognosis of patients with polymyositis and dermatomyositis. | 2016 | Int J Rheum Dis | pmid:27457756 |
| Robinson CL et al. | Posaconazole in lung transplant recipients: use, tolerability, and efficacy. | 2016 | Transpl Infect Dis | pmid:26781986 |
| Ishida H et al. | A Prospective Randomized, Comparative Trial of High-Dose Mizoribine Versus Mycophenolate Mofetil in Combination With Tacrolimus and Basiliximab for Living Donor Renal Transplant: A Multicenter Trial. | 2016 | Exp Clin Transplant | pmid:27733107 |
| Tsunashima D et al. | Preparation of extended release solid dispersion formulations of tacrolimus using ethylcellulose and hydroxypropylmethylcellulose by solvent evaporation method. | 2016 | J. Pharm. Pharmacol. | pmid:26773717 |
| Mok MM et al. | Acute Phosphate Nephropathy: An Under-Recognized Complication Leading to Impaired Allograft Function After Renal Transplant. | 2016 | Nephrology (Carlton) | pmid:27730726 |
| Bogossian H et al. | Expression of NO Synthase Under Medication with Cyclosporine A, Mycophenolate Mofetil, and Tacrolimus during Development of Transplant Vasculopathy on Rat Cardiac Allograft. | 2016 | Cardiovasc Ther | pmid:26924260 |
| RodrÃguez-Lago I et al. | Previous exposure to biologics and C-reactive protein are associated with the response to tacrolimus in inflammatory bowel disease. | 2016 | Rev Esp Enferm Dig | pmid:27604685 |
| Shuker N et al. | A Randomized Controlled Trial Comparing the Efficacy of Cyp3a5 Genotype-Based With Body-Weight-Based Tacrolimus Dosing After Living Donor Kidney Transplantation. | 2016 | Am. J. Transplant. | pmid:26714287 |
| Jun H et al. | Clinical advantages including medication adherence with conversion to once-daily advagraf and sirolimus combination in stable kidney recipients. | 2016 | Int J Clin Pharmacol Ther | pmid:26709601 |
| Kronbichler A et al. | Moderator's view: The use of calcineurin inhibitors in the treatment of lupus nephritis. | 2016 | Nephrol. Dial. Transplant. | pmid:27591329 |
| Juvvadi PR et al. | Novel motif in calcineurin catalytic subunit is required for septal localization of calcineurin in Aspergillus fumigatus. | 2016 | FEBS Lett. | pmid:26864964 |
| Wang L et al. | Therapeutic advances for primary biliary cholangitis: the old and the new. | 2016 | Eur J Gastroenterol Hepatol | pmid:26862931 |
| Navarro-Villarán E et al. | Differential Antitumoral Properties and Renal-Associated Tissue Damage Induced by Tacrolimus and Mammalian Target of Rapamycin Inhibitors in Hepatocarcinoma: In Vitro and In Vivo Studies. | 2016 | PLoS ONE | pmid:27518575 |
| Ben Fredj N et al. | Modeling of Tacrolimus Exposure in Kidney Transplant According to Posttransplant Time Based on Routine Trough Concentration Data. | 2016 | Exp Clin Transplant | pmid:27506258 |
| Hirsch HH et al. | BK Polyomavirus Replication in Renal Tubular Epithelial Cells Is Inhibited by Sirolimus, but Activated by Tacrolimus Through a Pathway Involving FKBP-12. | 2016 | Am. J. Transplant. | pmid:26639422 |
| Griffin SP and Nelson JE | Impact of a Clinical Solid Organ Transplant Pharmacist on Tacrolimus Nephrotoxicity, Therapeutic Drug Monitoring, and Institutional Revenue Generation in Adult Kidney Transplant Recipients. | 2016 | Prog Transplant | pmid:27628498 |
| Faraj W et al. | Osteoporosis in Pediatric Liver Transplantation. | 2016 | Prog Transplant | pmid:27555069 |
| Saliba F et al. | Corticosteroid-Sparing and Optimization of Mycophenolic Acid Exposure in Liver Transplant Recipients Receiving Mycophenolate Mofetil and Tacrolimus: A Randomized, Multicenter Study. | 2016 | Transplantation | pmid:27454919 |
| Liu XX et al. | Limited Sampling Strategy for the Estimation of Tacrolimus Area Under the Concentration-Time Curve in Chinese Adult Liver Transplant Patients. | 2016 | Pharmacology | pmid:27449772 |
| Butts AR et al. | Factors associated with optimized tacrolimus dosing in hematopoietic stem cell transplantation. | 2016 | J Oncol Pharm Pract | pmid:25802301 |
| Chan SW et al. | Associations of the CYP3A5*3 and CYP3A4*1G polymorphisms with the pharmacokinetics of oral midazolam and the urinary 6β-hydroxycortisol/cortisol ratio as markers of CYP3A activity in healthy male Chinese. | 2016 | J Clin Pharm Ther | pmid:27511886 |
| Zhao CY et al. | External evaluation of published population pharmacokinetic models of tacrolimus in adult renal transplant recipients. | 2016 | Br J Clin Pharmacol | pmid:26574188 |
| Seo J et al. | Therapeutic advantage of inhaled tacrolimus-bound albumin nanoparticles in a bleomycin-induced pulmonary fibrosis mouse model. | 2016 | Pulm Pharmacol Ther | pmid:26768967 |
| Zhang X et al. | The effect of calcineurin inhibitors in the induction and maintenance treatment of lupus nephritis: a systematic review and meta-analysis. | 2016 | Int Urol Nephrol | pmid:26781720 |
| Ayyala RS et al. | Imaging findings in a child with calcineurin inhibitor-induced pain syndrome after bone marrow transplant for beta thalassemia major. | 2016 | Pediatr Radiol | pmid:27324395 |
| Luo X et al. | Prediction of tacrolimus metabolism and dosage requirements based on CYP3A4 phenotype and CYP3A5(*)3 genotype in Chinese renal transplant recipients. | 2016 | Acta Pharmacol. Sin. | pmid:26924289 |
| Lien YH | Top 10 Things Primary Care Physicians Should Know About Maintenance Immunosuppression for Transplant Recipients. | 2016 | Am. J. Med. | pmid:26714210 |
| Wilkes SR et al. | How Clinically Relevant Are Treatment Comparisons of Topical Calcineurin Inhibitor Trials for Atopic Eczema? | 2016 | J. Invest. Dermatol. | pmid:27265005 |
| Miura M et al. | Inter-laboratory Variability of Current Immunoassay Methods for Tacrolimus among Japanese Hospitals. | 2016 | Biol. Pharm. Bull. | pmid:27263473 |
| Weiner SM | [Combination of tacrolimus and MMF for treatment of proliferative lupus nephritis]. | 2016 | Z Rheumatol | pmid:27259912 |
| Gaynor JJ et al. | Lower tacrolimus trough levels are associated with subsequently higher acute rejection risk during the first 12 months after kidney transplantation. | 2016 | Transpl. Int. | pmid:26442829 |
| Ha DH et al. | Effects of tacrolimus on morphology, proliferation and differentiation of mesenchymal stem cells derived from gingiva tissue. | 2016 | Mol Med Rep | pmid:27177273 |
| Jin J et al. | Klotho Deficiency Aggravates Tacrolimus-Induced Renal Injury via the Phosphatidylinositol 3-Kinase-Akt-Forkhead Box Protein O Pathway. | 2016 | Am. J. Nephrol. | pmid:27174564 |
| Dasgupta A et al. | Analytical Performance Evaluation of a New Cobas Tacrolimus Assay on Cobas e411 Analyzer: Comparison of Values Obtained by the CMIA Tacrolimus Assay and a Liquid Chromatography Combined with Tandem Mass Spectrometric Method. | 2016 | Ann. Clin. Lab. Sci. | pmid:27098629 |
| Otte JB | Pediatric liver transplantation: Personal perspectives on historical achievements and future challenges. | 2016 | Liver Transpl. | pmid:27096329 |
| Krejci K et al. | Clinical experience of conversion from cyclosporine to tacrolimus prolonged-release in stabilized kidney transplant patients. | 2016 | Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub | pmid:27174195 |
| Muduma G et al. | A cost-utility analysis of prolonged-release tacrolimus relative to immediate-release tacrolimus and ciclosporin in liver transplant recipients in the UK. | 2016 | J Med Econ | pmid:27172118 |
| Alagoz S et al. | Gangliocytoma Presenting With Tacrolimus Neurotoxicity in a Renal Transplant Recipient: Case Report. | 2016 | Transplant. Proc. | pmid:27932167 |
| Wakamatsu A et al. | Role of calcineurin (CN) in kidney glomerular podocyte: CN inhibitor ameliorated proteinuria by inhibiting the redistribution of CN at the slit diaphragm. | 2016 | Physiol Rep | pmid:27009276 |
| Sugitani A et al. | Unusual case of tacrolimus vascular toxicity after deceased donor renal transplantation. | 2016 | Nephrology (Carlton) | pmid:27004749 |
| Oddis CV | Update on the pharmacological treatment of adult myositis. | 2016 | J. Intern. Med. | pmid:27098592 |