| MeSH term | MeSH ID | Detail |
|---|---|---|
| Edema | D004487 | 152 associated lipids |
| Precancerous Conditions | D011230 | 48 associated lipids |
| Postoperative Complications | D011183 | 5 associated lipids |
| Arthritis | D001168 | 41 associated lipids |
| Arthritis, Experimental | D001169 | 24 associated lipids |
| Surgical Wound Infection | D013530 | 7 associated lipids |
| Neoplasm Recurrence, Local | D009364 | 5 associated lipids |
| Osteonecrosis | D010020 | 5 associated lipids |
| Hypotension | D007022 | 41 associated lipids |
| Acute Kidney Injury | D058186 | 34 associated lipids |
tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (2)
- Am. J. Physiol. Renal Physiol. (1)
- Drug Metab. Dispos. (1)
- Others (1)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Lee YH and Song GG | Relative efficacy and safety of tacrolimus, mycophenolate mofetil, and cyclophosphamide as induction therapy for lupus nephritis: a Bayesian network meta-analysis of randomized controlled trials. | 2015 | Lupus | pmid:26162684 |
| Hu L et al. | Severe Tacrolimus-Induced Granulomatous Rosacea Recalcitrant to Oral Tetracyclines. | 2015 | J Drugs Dermatol | pmid:26091390 |
| Melilli E et al. | De novo use of a generic formulation of tacrolimus versus reference tacrolimus in kidney transplantation: evaluation of the clinical results, histology in protocol biopsies, and immunological monitoring. | 2015 | Transpl. Int. | pmid:26088437 |
| Traitanon O et al. | Differential Effects of Tacrolimus versus Sirolimus on the Proliferation, Activation and Differentiation of Human B Cells. | 2015 | PLoS ONE | pmid:26087255 |
| Boukoum H et al. | BK and JC polyomavirus infections in Tunisian renal transplant recipients. | 2015 | J. Med. Virol. | pmid:25952258 |
| Lee J et al. | A 12-month single arm pilot study to evaluate the efficacy and safety of sirolimus in combination with tacrolimus in kidney transplant recipients at high immunologic risk. | 2015 | J. Korean Med. Sci. | pmid:26028917 |
| Mabuchi M et al. | Improvement of solid material for affinity resins by application of long PEG spacers to capture the whole target complex of FK506. | 2015 | Bioorg. Med. Chem. Lett. | pmid:26025877 |
| Zhang D et al. | Multifunctional Poly(methyl vinyl ether-co-maleic anhydride)-graft-hydroxypropyl-β-cyclodextrin Amphiphilic Copolymer as an Oral High-Performance Delivery Carrier of Tacrolimus. | 2015 | Mol. Pharm. | pmid:26024817 |
| Huang G et al. | [Analysis on BK virus associated nephropathy related risk factors in renal transplant recipients]. | 2015 | Zhonghua Yi Xue Za Zhi | pmid:26814103 |
| Shu WY et al. | Pharmacogenomics and personalized medicine: a review focused on their application in the Chinese population. | 2015 | Acta Pharmacol. Sin. | pmid:25891088 |
| Baird K et al. | Imatinib mesylate for the treatment of steroid-refractory sclerotic-type cutaneous chronic graft-versus-host disease. | 2015 | Biol. Blood Marrow Transplant. | pmid:25771402 |
| Shuker N et al. | Conversion from twice-daily to once-daily tacrolimus does not reduce intrapatient variability in tacrolimus exposure. | 2015 | Ther Drug Monit | pmid:25265255 |
| Wang X et al. | Tacrolimus 0.03% ointment in labial discoid lupus erythematosus: A randomized, controlled clinical trial. | 2015 | J Clin Pharmacol | pmid:25951426 |
| Ding L et al. | Clinical Immunosuppressants Inhibit Inflammatory, Proliferative, and Reprogramming Potential, But Not Angiogenesis of Human Pancreatic Duct Cells. | 2015 | Cell Transplant | pmid:25198311 |
| Ã…berg F et al. | Asymptomatic De Novo Inflammatory Bowel Disease Late After Liver Transplantation for Primary Sclerosing Cholangitis: A Case Report. | 2015 | Transplant. Proc. | pmid:26680092 |
| Rojanathammanee L et al. | Attenuation of microglial activation in a mouse model of Alzheimer's disease via NFAT inhibition. | 2015 | J Neuroinflammation | pmid:25889879 |
| Størset E et al. | Improved Tacrolimus Target Concentration Achievement Using Computerized Dosing in Renal Transplant Recipients--A Prospective, Randomized Study. | 2015 | Transplantation | pmid:25886918 |
| Montero N and Pascual J | Immunosuppression and Post-transplant Hyperglycemia. | 2015 | Curr Diabetes Rev | pmid:25824238 |
| Reig Mezquida JP et al. | Thrombotic microangiopathy associated with tacrolimus in lung transplantation. | 2015 | Arch. Bronconeumol. | pmid:25138798 |
| Vollmar J et al. | Efficacy and safety of a conversion from the original tacrolimus and mycophenolate mofetil to the generics Tacpan and Mowel after liver transplantation. | 2015 | Drug Des Devel Ther | pmid:26604701 |
| Eichenfield DZ and Eichenfield LF | Pimecrolimus is safe and effective in treating atopic dermatitis. | 2015 | J. Pediatr. | pmid:26603713 |
| Calabrese B and Halpain S | Differential targeting of dynamin-1 and dynamin-3 to nerve terminals during chronic suppression of neuronal activity. | 2015 | Mol. Cell. Neurosci. | pmid:25827095 |
| Li Z et al. | Tacrolimus Induces Insulin Resistance and Increases the Glucose Absorption in the Jejunum: A Potential Mechanism of the Diabetogenic Effects. | 2015 | PLoS ONE | pmid:26599323 |
| Madariaga ML et al. | Kidney-induced cardiac allograft tolerance in miniature swine is dependent on MHC-matching of donor cardiac and renal parenchyma. | 2015 | Am. J. Transplant. | pmid:25824550 |
| Wang YY et al. | Biochemical characterization of a malonyl-specific acyltransferase domain of FK506 biosynthetic polyketide synthase. | 2015 | Protein Pept. Lett. | pmid:25267255 |
| Cendales L et al. | Tacrolimus to Belatacept Conversion Following Hand Transplantation: A Case Report. | 2015 | Am. J. Transplant. | pmid:25773260 |
| Soylu H et al. | Survival of renal transplant patients: data from a tertiary care center in Turkey. | 2015 | Transplant. Proc. | pmid:25769571 |
| Singh N et al. | Extended release once a day tacrolimus. | 2015 | Curr Opin Organ Transplant | pmid:26536429 |
| Ohe M and Bohgaki T | A Case of Adult-Onset Still's Disease Treated with Monitoring of Serum Tacrolimus Levels. | 2015 | Bull Hosp Jt Dis (2013) | pmid:26535602 |
| Abdel-Azim H et al. | Unrelated donor hematopoietic stem cell transplantation for the treatment of non-malignant genetic diseases: An alemtuzumab based regimen is associated with cure of clinical disease; earlier clearance of alemtuzumab may be associated with graft rejection. | 2015 | Am. J. Hematol. | pmid:26242764 |
| Liu X et al. | Associations of HSD11B1 polymorphisms with tacrolimus concentrations in Chinese renal transplant recipients with prednisone combined therapy. | 2015 | Drug Metab. Dispos. | pmid:25587129 |
| Guethoff S et al. | De novo sirolimus with low-dose tacrolimus versus full-dose tacrolimus with mycophenolate mofetil after heart transplantation--8-year results. | 2015 | J. Heart Lung Transplant. | pmid:25701373 |
| Pensi D et al. | An UPLC-MS/MS method coupled with automated on-line SPE for quantification of tacrolimus in peripheral blood mononuclear cells. | 2015 | J Pharm Biomed Anal | pmid:25698619 |
| Roche NA et al. | Long-Term Multifunctional Outcome and Risks of Face Vascularized Composite Allotransplantation. | 2015 | J Craniofac Surg | pmid:26468783 |
| Ishida K et al. | Evaluation of the Safety and Effectiveness of Add-On Tacrolimus in Patients with Rheumatoid Arthritis Who Failed to Show an Adequate Response to Biological DMARDs: The Interim Results of a Specific Drug Use-Results Survey of Tacrolimus. | 2015 | Drugs R D | pmid:26386566 |
| Chow SP et al. | Long-Term Outcomes of High-Risk Keratoplasty in Patients Receiving Systemic Immunosuppression. | 2015 | Cornea | pmid:26382894 |
| Lin NC et al. | Minimization or withdrawal of immunosuppressants in pediatric liver transplant recipients. | 2015 | J. Pediatr. Surg. | pmid:26377868 |
| Ogul H et al. | Severe toxic leukoencephalopathy associated with tacrolimus after living donor liver transplantation. | 2015 | Acta Neurol Belg | pmid:24854146 |
| Pallet N et al. | Kidney transplant recipients carrying the CYP3A4*22 allelic variant have reduced tacrolimus clearance and often reach supratherapeutic tacrolimus concentrations. | 2015 | Am. J. Transplant. | pmid:25588704 |
| Krystel-Whittemore M et al. | Polyomavirus nephropathy of the native kidney in a patient with rheumatoid arthritis and pulmonary fibrosis. | 2015 | BMJ Case Rep | pmid:26318171 |
| Aikawa Y et al. | Essential role of PU.1 in maintenance of mixed lineage leukemia-associated leukemic stem cells. | 2015 | Cancer Sci. | pmid:25529853 |
| Ãœnal CM and Steinert M | FKBPs in bacterial infections. | 2015 | Biochim. Biophys. Acta | pmid:25529296 |
| Higa M et al. | Spatial control of calcineurin in response to heat shock in fission yeast. | 2015 | Genes Cells | pmid:25529221 |
| Joshi S et al. | Phosphatase inhibition prevents the activity-dependent trafficking of GABAA receptors during status epilepticus in the young animal. | 2015 | Epilepsia | pmid:26248944 |
| Duvoux C et al. | Sustained virological response to antiviral therapy in a randomized trial of cyclosporine versus tacrolimus in liver transplant patients with recurrent hepatitis C infection. | 2015 | Ann. Transplant. | pmid:25588713 |
| Hoerning A et al. | Pharmacodynamic monitoring of mammalian target of rapamycin inhibition by phosphoflow cytometric determination of p70S6 kinase activity. | 2015 | Transplantation | pmid:25099702 |
| Wu B et al. | Triple immunosuppressive therapy in steroid-resistant nephrotic syndrome children with tacrolimus resistance or tacrolimus sensitivity but frequently relapsing. | 2015 | Nephrology (Carlton) | pmid:25312783 |
| Huang G et al. | Monitoring of polyomavirus BK replication and impact of preemptive immunosuppression reduction in renal-transplant recipients in China: a 5-year single-center analysis. | 2015 | Diagn. Microbiol. Infect. Dis. | pmid:25445121 |
| Apalla Z et al. | Psoriatic cheilitis: a report of 2 cases treated successfully with topical tacrolimus and a review of the literature. | 2015 | Actas Dermosifiliogr | pmid:26164836 |
| Vives R et al. | Safety and Activity of UR-1505 in Atopic Dermatitis: A Randomized, Double-blind Phase II Exploratory Trial. | 2015 | Clin Ther | pmid:26163200 |