tacrolimus

Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.

Cross Reference

Introduction

To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with tacrolimus?

tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with tacrolimus

MeSH term MeSH ID Detail
Edema D004487 152 associated lipids
Precancerous Conditions D011230 48 associated lipids
Postoperative Complications D011183 5 associated lipids
Arthritis D001168 41 associated lipids
Arthritis, Experimental D001169 24 associated lipids
Surgical Wound Infection D013530 7 associated lipids
Neoplasm Recurrence, Local D009364 5 associated lipids
Osteonecrosis D010020 5 associated lipids
Hypotension D007022 41 associated lipids
Acute Kidney Injury D058186 34 associated lipids
Per page 10 20 50 100 | Total 613

PubChem Associated disorders and diseases

What pathways are associated with tacrolimus

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with tacrolimus?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with tacrolimus?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with tacrolimus?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with tacrolimus?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with tacrolimus?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with tacrolimus

Download all related citations
Per page 10 20 50 100 | Total 15051
Authors Title Published Journal PubMed Link
Radziejewski K et al. Assessment of corneal and conjunctival metaplasia by impression cytology during the treatment of canine keratoconjunctivitis sicca. 2018 Acta Vet. Hung. pmid:29958527
Hasegawa M et al. Diagnostic criteria, severity classification and guidelines of lichen sclerosus et atrophicus. 2018 J. Dermatol. pmid:29265410
Gómez-Bravo MA et al. Influence of donor liver CYP3A4*20 loss-of-function genotype on tacrolimus pharmacokinetics in transplanted patients. 2018 Pharmacogenet. Genomics pmid:29256966
Tanaka Y et al. Cooperation between ER stress and calcineurin signaling contributes to the maintenance of cell wall integrity in Candida glabrata. 2018 Fungal Biol pmid:29248112
Sikma MA et al. Association of Whole Blood Tacrolimus Concentrations with Kidney Injury in Heart Transplantation Patients. 2018 Eur J Drug Metab Pharmacokinet pmid:29236211
Motta A et al. Immunohistopathological characterization and the impact of topical immunomodulatory therapy in oral chronic graft-versus-host disease: A pilot study. 2018 Oral Dis pmid:29197137
Jackson Cullison SR and Siegfried EC Paradoxic eczema in infants after heart transplantation. 2018 Pediatr Dermatol pmid:29194735
Leiskau C et al. Side effects and efficacy of renal sparing immunosuppression in pediatric liver transplantation-A single center matched cohort study. 2018 Pediatr Transplant pmid:29729061
Cuñetti L et al. Chronic Pain Treatment With Cannabidiol in Kidney Transplant Patients in Uruguay. 2018 Transplant. Proc. pmid:29579828
Armenta Bautista A et al. Renal Transplantation in Second-Level Private Hospitals in the State of Mexico. 2018 Transplant. Proc. pmid:29579825
Shuker N et al. Intrapatient Variability in Tacrolimus Exposure Does Not Predict The Development of Cardiac Allograft Vasculopathy After Heart Transplant. 2018 Exp Clin Transplant pmid:28969528
Bae SC and Lee YH Comparative efficacy and tolerability of monotherapy with leflunomide or tacrolimus for the treatment of rheumatoid arthritis: a Bayesian network meta-analysis of randomized controlled trials. 2018 Clin. Rheumatol. pmid:28967035
Zhang H et al. Prediction of Drug-Drug Interaction between Tacrolimus and Principal Ingredients of Wuzhi Capsule in Chinese Healthy Volunteers Using Physiologically-Based Pharmacokinetic Modelling. 2018 Basic Clin. Pharmacol. Toxicol. pmid:28945011
González-Vílchez F et al. Efficacy and Safety of de Novo and Early Use of Extended-release Tacrolimus in Heart Transplantation. 2018 Rev Esp Cardiol (Engl Ed) pmid:28545984
Zheng CS et al. Assessment of the synergic effect of immunomodulation on nerve repair using multiparametric magnetic resonance imaging. 2018 Muscle Nerve pmid:28445921
Al-Lawati H et al. Nanomedicine for immunosuppressive therapy: achievements in pre-clinical and clinical research. 2018 Expert Opin Drug Deliv pmid:29261332
Ayala E et al. Haploidentical transplantation as a promising therapy for relapsed hemophagocytic lymphohistiocytosis in an older adult patient. 2018 Hematol Oncol Stem Cell Ther pmid:27352259
Gómez-Ríos GA et al. Rapid determination of immunosuppressive drug concentrations in whole blood by coated blade spray-tandem mass spectrometry (CBS-MS/MS). 2018 Anal. Chim. Acta pmid:29254576
Park CS et al. Tetrahydrocurcumin Ameliorates Tacrolimus-Induced Nephrotoxicity Via Inhibiting Apoptosis. 2018 Transplant. Proc. pmid:30401411
Hiramatsu Y et al. Changes in the blood level, efficacy, and safety of tacrolimus in pregnancy and the lactation period in patients with systemic lupus erythematosus. 2018 Lupus pmid:30394835
Ordóñez-Robles M et al. Genome-wide transcriptome response of Streptomyces tsukubaensis to N-acetylglucosamine: effect on tacrolimus biosynthesis. 2018 Microbiol. Res. pmid:30384905
Hamano I et al. Condyloma Acuminata of the Urethra in a Male Renal Transplant Recipient: A Case Report. 2018 Transplant. Proc. pmid:30316397
Thoms S et al. Tacrolimus inhibits angiogenesis and induces disaggregation of endothelial cells in spheroids - Toxicity testing in a 3D cell culture approach. 2018 Toxicol In Vitro pmid:30048735
Kaneko T et al. Comparison of whole-blood tacrolimus concentrations measured by different immunoassay systems. 2018 J. Clin. Lab. Anal. pmid:29974517
Saengram W et al. Extended release versus immediate release tacrolimus in kidney transplant recipients: a systematic review and meta-analysis. 2018 Eur. J. Clin. Pharmacol. pmid:29961086
Tunnicliffe DJ et al. Immunosuppressive treatment for proliferative lupus nephritis. 2018 Cochrane Database Syst Rev pmid:29957821
Htun YY et al. CYP3A5*3 Genetic Polymorphism and Tacrolimus Concentration in Myanmar Renal Transplant Patients. 2018 Transplant. Proc. pmid:29731062
Scherrer M et al. Tacrolimus-induced symmetric drug-related intertriginous and flexural exanthema (SDRIFE). 2018 Contact Derm. pmid:29722025
Del Bello A et al. High tacrolimus intra-patient variability is associated with graft rejection, and donor-specific antibodies occurrence after liver transplantation. 2018 World J. Gastroenterol. pmid:29713132
Lin G et al. Evaluation of tacrolimus-related CYP3A5 genotyping in China: Results from the First External Quality Assessment Exercise. 2018 J. Clin. Lab. Anal. pmid:29708622
Hu R et al. CYP3A5*3 and ABCB1 61A>G Significantly Influence Dose-adjusted Trough Blood Tacrolimus Concentrations in the First Three Months Post-Kidney Transplantation. 2018 Basic Clin. Pharmacol. Toxicol. pmid:29603629
Mücke VT et al. Low Serum Levels of (Dihydro-)Ceramides Reflect Liver Graft Dysfunction in a Real-World Cohort of Patients Post Liver Transplantation. 2018 Int J Mol Sci pmid:29587453
Cintra-Cabrera M et al. Resistant Cytomegalovirus Infection After Renal Transplantation: Literature Review. 2018 Transplant. Proc. pmid:29579856
Hong D et al. [Atopic keratoconjunctivitis: One allergy may mask another. A clinical observation with two types of hypersensitivity reactions: IgE-mediated and non-IgE-mediated]. 2018 J Fr Ophtalmol pmid:29567021
Davidson HE Shifting Paradigms in Caring for Older Adults. 2018 Consult Pharm pmid:29789044
Jouve T et al. Tailoring tacrolimus therapy in kidney transplantation. 2018 Expert Rev Clin Pharmacol pmid:29779413
Pircher C et al. A rare case of Epstein-Barr virus-associated hepatosplenic smooth muscle tumors after kidney transplantation. 2018 Transpl Infect Dis pmid:29427352
Yang Y et al. Chlormethine Hydrochloride is Not Inferior to Tacrolimus in Treating Steroid-Resistant Nephrotic Syndrome. 2018 Kidney Blood Press. Res. pmid:29402844
Gadby F et al. [Pulmonary granuloma in an immunodepressed patient]. 2018 Rev Mal Respir pmid:29395568
Onodera M et al. Tacrolimus Dose Optimization Strategy for Refractory Ulcerative Colitis Based on the Cytochrome P450 3A5 Polymorphism Prediction Using Trough Concentration after 24 Hours. 2018 Digestion pmid:29393157
Liu YC et al. A Biodegradable, Sustained-Released, Tacrolimus Microfilm Drug Delivery System for the Management of Allergic Conjunctivitis in a Mouse Model. 2018 Invest. Ophthalmol. Vis. Sci. pmid:29392313
Murad A et al. Primary cutaneous post liver transplant lymphoproliferative disorder (PTLD) successfully treated with radiotherapy. 2018 J Dermatolog Treat pmid:28604230
Rhu J et al. Clinical Implication of Mycophenolic Acid Trough Concentration Monitoring in Kidney Transplant Patients on a Tacrolimus Triple Maintenance Regimen: A Single-Center Experience. 2017 Ann. Transplant. pmid:29180612
Wang Y et al. Calcineurin Antagonizes AMPK to Regulate Lipolysis in Caenorhabditis elegans. 2017 Molecules pmid:28672869
Lee D et al. Age and Early Graft Function Relate With Risk-Benefit Ratio of Allogenic Islet Transplantation Under Antithymocyte Globulin-Mycophenolate Mofetil-Tacrolimus Immune Suppression. 2017 Transplantation pmid:27779572
Eleftheriadis T et al. In human cell cultures, everolimus is inferior to tacrolimus in inhibiting cellular alloimmunity, but equally effective as regards humoral alloimmunity. 2017 Int Urol Nephrol pmid:28508247
Banovic F et al. Therapeutic effectiveness of calcineurin inhibitors in canine vesicular cutaneous lupus erythematosus. 2017 Vet. Dermatol. pmid:28439997
Bhari N et al. Tacrolimus induced dermatophyte infection overlying a plaque morphea. 2017 Dermatol Ther pmid:27502443
Son SY et al. Comparison of the long-term efficacy and safety of generic Tacrobell with original tacrolimus (Prograf) in kidney transplant recipients. 2017 Drug Des Devel Ther pmid:28138224
Soiffer RJ et al. Prospective, Randomized, Double-Blind, Phase III Clinical Trial of Anti-T-Lymphocyte Globulin to Assess Impact on Chronic Graft-Versus-Host Disease-Free Survival in Patients Undergoing HLA-Matched Unrelated Myeloablative Hematopoietic Cell Transplantation. 2017 J. Clin. Oncol. pmid:29040031