tacrolimus

Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.

Cross Reference

Introduction

To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with tacrolimus?

tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with tacrolimus

MeSH term MeSH ID Detail
Edema D004487 152 associated lipids
Precancerous Conditions D011230 48 associated lipids
Postoperative Complications D011183 5 associated lipids
Arthritis D001168 41 associated lipids
Arthritis, Experimental D001169 24 associated lipids
Surgical Wound Infection D013530 7 associated lipids
Neoplasm Recurrence, Local D009364 5 associated lipids
Osteonecrosis D010020 5 associated lipids
Hypotension D007022 41 associated lipids
Acute Kidney Injury D058186 34 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with tacrolimus

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with tacrolimus?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with tacrolimus?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with tacrolimus?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with tacrolimus?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with tacrolimus?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with tacrolimus

Download all related citations
Per page 10 20 50 100 | Total 15051
Authors Title Published Journal PubMed Link
Drake M et al. The immunosuppressant FK506 ameliorates ischaemic damage in the rat brain. 1996 Acta Physiol. Scand. pmid:8899062
Ibarra FR et al. Intracellular sodium modulates the state of protein kinase C phosphorylation of rat proximal tubule Na+,K+-ATPase. 2002 Acta Physiol. Scand. pmid:12028137
Folwarczna J et al. Effect of low-dose tacrolimus coadministered with raloxifene on the skeletal system in male rats. 2009 Mar-Apr Acta Pol Pharm pmid:19719057
Turło J et al. Submerged cultivation of Streptomyces tsukubaensis in media composed of waste products of food industry. 2006 Sep-Oct Acta Pol Pharm pmid:17357618
Kaczmarczyk-Sedlak I et al. Raloxifene does not affect the changes in bone histomorphometric parameters induced by low dose tacrolimus in male rats. 2006 Jul-Aug Acta Pol Pharm pmid:17203868
Wartenberg KE et al. Transient diffusion-weighted imaging changes in a patient with reversible leukoencephalopathy syndrome. 2004 Acta Radiol pmid:15587428
Radziejewski K et al. Assessment of corneal and conjunctival metaplasia by impression cytology during the treatment of canine keratoconjunctivitis sicca. 2018 Acta Vet. Hung. pmid:29958527
Radziejewski K and Balicki I Comparative clinical evaluation of tacrolimus and cyclosporine eye drops for the treatment of canine keratoconjunctivitis sicca. 2016 Acta Vet. Hung. pmid:27653428
Kageyama S et al. Augmentation of natural killer cell activity induced by cytomegalovirus infection in mice treated with FK506. 1997 Acta Virol. pmid:9391652
Ormaechea-Pérez N et al. Superficial granulomatous pyoderma. Report of 2 cases treated with topical tacrolimus. 2013 Actas Dermosifiliogr pmid:23933249
de la Torre C [Alcohol intolerance with facial flushing due to topical pimecrolimus treatment]. 2008 Actas Dermosifiliogr pmid:18501181
García-Rabasco AE et al. [Pyoderma gangrenosum associated with hidradenitis suppurativa: a case report and review of the literature]. 2010 Actas Dermosifiliogr pmid:20965015
Gómez-Sánchez ME et al. Intralymphatic Histiocytosis: A Report of 2 Cases. Actas Dermosifiliogr pmid:28256202
Pitarch G and Giner F Periorbital necrobiosis lipoidica. 2013 Actas Dermosifiliogr pmid:23871211
Alomar A [Role of topical calcineurin inhibitors in dermatology]. 2008 Actas Dermosifiliogr pmid:18346422
García-Delgado R et al. Systemic Absorption of Topical Tacrolimus in Metastatic Crohn Disease With Skin Ulcers. 2016 Actas Dermosifiliogr pmid:27372545
Almeida P et al. [Vitiligo. Treatment of 12 cases with topical tacrolimus]. 2005 Actas Dermosifiliogr pmid:16476357
Pérez-López I et al. Koebner phenomenon in a patient with lichen sclerosus following a jellyfish sting: an exceptional morphology. 2015 Actas Dermosifiliogr pmid:25597413
Ojeda T et al. [Ulcerative lichen planus of the sole treated with tacrolimus, 0.1%]. 2011 Actas Dermosifiliogr pmid:21345398
Apalla Z et al. Psoriatic cheilitis: a report of 2 cases treated successfully with topical tacrolimus and a review of the literature. 2015 Actas Dermosifiliogr pmid:26164836