tacrolimus

Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.

Cross Reference

Introduction

To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with tacrolimus?

tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with tacrolimus

MeSH term MeSH ID Detail
Beckwith-Wiedemann Syndrome D001506 1 associated lipids
Cholecystolithiasis D041761 2 associated lipids
Budd-Chiari Syndrome D006502 1 associated lipids
Idiopathic Interstitial Pneumonias D054988 1 associated lipids
Acneiform Eruptions D017486 3 associated lipids
Rheumatoid Nodule D012218 1 associated lipids
Granuloma Annulare D016460 1 associated lipids
Hypoplastic Left Heart Syndrome D018636 1 associated lipids
Incontinentia Pigmenti D007184 2 associated lipids
Discitis D015299 2 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with tacrolimus

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with tacrolimus?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with tacrolimus?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with tacrolimus?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with tacrolimus?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with tacrolimus?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with tacrolimus

Download all related citations
Per page 10 20 50 100 | Total 15051
Authors Title Published Journal PubMed Link
Meng QH et al. Falsely elevated tacrolimus concentrations on the Dimension Xpand. 2015 Clin. Biochem. pmid:26160209
Fischer L et al. Three-year Outcomes in De Novo Liver Transplant Patients Receiving Everolimus With Reduced Tacrolimus: Follow-Up Results From a Randomized, Multicenter Study. 2015 Transplantation pmid:26151607
Shamsudin N et al. Objective assessment of vitiligo with a computerised digital imaging analysis system. 2015 Australas. J. Dermatol. pmid:25367709
Lee SC et al. Calcineurin orchestrates dimorphic transitions, antifungal drug responses and host-pathogen interactions of the pathogenic mucoralean fungus Mucor circinelloides. 2015 Mol. Microbiol. pmid:26010100
Kedzierska K et al. The effect of immunosuppressive therapy on renal cell apoptosis in native rat kidneys. 2015 Histol. Histopathol. pmid:25029518
Sato K et al. Late onset of progressive speech impairment due to tacrolimus-associated leukoencephalopathy after kidney transplantation. 2015 Int Urol Nephrol pmid:26071870
Pulk RA et al. Multigene predictors of tacrolimus exposure in kidney transplant recipients. 2015 Pharmacogenomics pmid:26067485
Hollis IB et al. Medication management of cardiac allograft vasculopathy after heart transplantation. 2015 Pharmacotherapy pmid:26011142
Chen YB et al. Phase II Trial of Tandem High-Dose Chemotherapy with Autologous Stem Cell Transplantation Followed by Reduced-Intensity Allogeneic Stem Cell Transplantation for Patients with High-Risk Lymphoma. 2015 Biol. Blood Marrow Transplant. pmid:26009261
Ribero S et al. Efficacy of topical tacrolimus for oral lichen planus: real-life experience in a retrospective cohort of patients with a review of the literature. 2015 J Eur Acad Dermatol Venereol pmid:25308924
Qasim W et al. Immunotherapy of HCC metastases with autologous T cell receptor redirected T cells, targeting HBsAg in a liver transplant patient. 2015 J. Hepatol. pmid:25308176
Andreu F et al. Development of a population PK model of tacrolimus for adaptive dosage control in stable kidney transplant patients. 2015 Ther Drug Monit pmid:25254416
Fussner LA et al. Cardiovascular disease after liver transplantation: When, What, and Who Is at Risk. 2015 Liver Transpl. pmid:25880971
Abuabara K et al. Atopic dermatitis disease control and age: A cohort study. 2015 J. Allergy Clin. Immunol. pmid:25935107
Bonanni A et al. Low-dose ofatumumab for rituximab-resistant nephrotic syndrome. 2015 BMJ Case Rep pmid:26376698
Clark SL et al. Making every drop count for pediatric kidney transplant patients. 2015 Hosp Pediatr pmid:25934814
Ikitimur B et al. Long-Term Impact of Different Immunosuppressive Drugs on QT and PR Intervals in Renal Transplant Patients. 2015 Ann Noninvasive Electrocardiol pmid:25367596
Ganetsky A et al. Lack of a significant pharmacokinetic interaction between maraviroc and tacrolimus in allogeneic HSCT recipients. 2015 J. Antimicrob. Chemother. pmid:25881619
Liang GB et al. Impact of immunosuppressive agents on the expression of indoleamine 2,3-dioxygenase, heme oxygenase-1 and interleukin-7 in mesangial cells. 2015 Mol Med Rep pmid:25936769
Söderlund C and Rådegran G Immunosuppressive therapies after heart transplantation--The balance between under- and over-immunosuppression. 2015 Transplant Rev (Orlando) pmid:25812489
Zegarska J et al. Mycophenolic Acid Metabolites Acyl-Glucuronide and Glucoside Affect the Occurrence of Infectious Complications and Bone Marrow Dysfunction in Liver Transplant Recipients. 2015 Ann. Transplant. pmid:26313036
Naito T et al. ABCB1 genetic variant and its associated tacrolimus pharmacokinetics affect renal function in patients with rheumatoid arthritis. 2015 Clin. Chim. Acta pmid:25817604
Lee JR et al. Gut microbiota and tacrolimus dosing in kidney transplantation. 2015 PLoS ONE pmid:25815766
Honda Y et al. Disseminated Mycobacterium mantenii infection with multiple purulent cutaneous lesions. 2015 Acta Derm. Venereol. pmid:25881714
Stevens RB et al. A randomized 2×2 factorial trial, part 1: single-dose rabbit antithymocyte globulin induction may improve renal transplantation outcomes. 2015 Transplantation pmid:25083614
Ravaioli M et al. Immunosuppression Modifications Based on an Immune Response Assay: Results of a Randomized, Controlled Trial. 2015 Transplantation pmid:25757214
Bis DM et al. Characterization of the nocardiopsin biosynthetic gene cluster reveals similarities to and differences from the rapamycin and FK-506 pathways. 2015 Chembiochem pmid:25755076
Devine SM et al. Phase II Study of Allogeneic Transplantation for Older Patients With Acute Myeloid Leukemia in First Complete Remission Using a Reduced-Intensity Conditioning Regimen: Results From Cancer and Leukemia Group B 100103 (Alliance for Clinical Trials in Oncology)/Blood and Marrow Transplant Clinical Trial Network 0502. 2015 J. Clin. Oncol. pmid:26527780
Pennington CA et al. Evaluation of a Weight-based Rabbit Anti-thymocyte Globulin Induction Dosing Regimen for Kidney Transplant Recipients. 2015 Pharmacotherapy pmid:26234282
Zhu L et al. Adrenergic stimulation sensitizes TRPV1 through upregulation of cystathionine β-synthetase in a rat model of visceral hypersensitivity. 2015 Sci Rep pmid:26527188
Staatz CE et al. Tacrolimus pharmacokinetics after kidney transplantation--Influence of changes in haematocrit and steroid dose. 2015 Br J Clin Pharmacol pmid:26235203
Vanhove T et al. Response to 'Tacrolimus pharmacokinetics after kidney transplantation--Influence of changes in haematocrit and steroid dose'. 2015 Br J Clin Pharmacol pmid:26235051
Vardas PN et al. Identification and management of atypical hemolytic uremic syndrome immediately post-heart transplantation. 2015 J Card Surg pmid:25693626
Hanifin JM A Reassuring Rejoinder Against Malignant Influences of Topical Calcineurin Use in Children. 2015 JAMA Dermatol pmid:25692944
Margolis DJ et al. Association Between Malignancy and Topical Use of Pimecrolimus. 2015 JAMA Dermatol pmid:25692459
Fan DM et al. Successful ABO-incompatible living-related intestinal transplantation: a 2-year follow-up. 2015 Am. J. Transplant. pmid:25808777
Stevens RB et al. A Randomized 2x2 Factorial Clinical Trial of Renal Transplantation: Steroid-Free Maintenance Immunosuppression with Calcineurin Inhibitor Withdrawal after Six Months Associates with Improved Renal Function and Reduced Chronic Histopathology. 2015 PLoS ONE pmid:26465152
Cai W et al. Limited sampling strategy for predicting area under the concentration-time curve for mycophenolic Acid in Chinese adults receiving mycophenolate mofetil and tacrolimus early after renal transplantation. 2015 Ther Drug Monit pmid:25525761
Leneghan D and Bell A Immunophilin-protein interactions in Plasmodium falciparum. 2015 Parasitology pmid:26156578
Chen QJ et al. Tacrolimus decreases insulin sensitivity without reducing fasting insulin concentration: a 2-year follow-up study in kidney transplant recipients. 2015 Ren Fail pmid:25644968
Joneja U and Uppal G Pseudo-Pelger-Huët anomaly in a patient on tacrolimus. 2015 Blood pmid:26371350
Kawahara T et al. Cyclosporine A and tacrolimus inhibit bladder cancer growth through down-regulation of NFATc1. 2015 Oncotarget pmid:25638160
Dagher M et al. Overweight, central obesity, and cardiometabolic risk factors in pediatric liver transplantation. 2015 Pediatr Transplant pmid:25581506
Kita A et al. Imp2, the PSTPIP homolog in fission yeast, affects sensitivity to the immunosuppressant FK506 and membrane trafficking in fission yeast. 2015 Biochem. Biophys. Res. Commun. pmid:25580011
Annunziato RA et al. Can transition to adult care for transplant recipients be improved by intensified services while patients are still in pediatrics? 2015 Prog Transplant pmid:26308783
Kurita T et al. The efficacy of tacrolimus in patients with interstitial lung diseases complicated with polymyositis or dermatomyositis. 2015 Rheumatology (Oxford) pmid:24764266
Cavalié M et al. Maintenance therapy of adult vitiligo with 0.1% tacrolimus ointment: a randomized, double blind, placebo-controlled study. 2015 J. Invest. Dermatol. pmid:25521460
Li YX and Dijkers PF Specific calcineurin isoforms are involved in Drosophila toll immune signaling. 2015 J. Immunol. pmid:25429067
Allison SJ Lupus nephritis: Multitarget induction therapy for LN. 2015 Nat Rev Nephrol pmid:25421833
Tan ES et al. Effective treatment of scrotal lichen simplex chronicus with 0.1% tacrolimus ointment: an observational study. 2015 J Eur Acad Dermatol Venereol pmid:24666218