| MeSH term | MeSH ID | Detail |
|---|---|---|
| Arthritis, Reactive | D016918 | 3 associated lipids |
| Akinetic Mutism | D000405 | 1 associated lipids |
| Pityriasis Lichenoides | D017514 | 2 associated lipids |
| Histiocytosis | D015614 | 2 associated lipids |
| Mastocytosis, Cutaneous | D034701 | 1 associated lipids |
| Mediastinal Emphysema | D008478 | 1 associated lipids |
| Invasive Pulmonary Aspergillosis | D055744 | 1 associated lipids |
| Netherton Syndrome | D056770 | 1 associated lipids |
| Coccidioidomycosis | D003047 | 2 associated lipids |
| Meningitis, Fungal | D016921 | 1 associated lipids |
tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Adams PS et al. | Postoperative cardiac tamponade after kidney transplantation: a possible consequence of alemtuzumab-induced cytokine release syndrome. | 2013 | Transplantation | pmid:23380870 |
| Tsuchiya N et al. | Influence of CYP3A5 and MDR1 (ABCB1) polymorphisms on the pharmacokinetics of tacrolimus in renal transplant recipients. | 2004 | Transplantation | pmid:15502717 |
| Jindal RM et al. | Serum lipid changes in liver transplant recipients in a prospective trial of cyclosporine versus FK506. | 1994 | Transplantation | pmid:7514317 |
| Todo S et al. | Abdominal multivisceral transplantation. | 1995 | Transplantation | pmid:7530873 |
| Vu MD et al. | Tacrolimus (FK506) and sirolimus (rapamycin) in combination are not antagonistic but produce extended graft survival in cardiac transplantation in the rat. | 1997 | Transplantation | pmid:9422432 |
| David-Neto E et al. | The dynamics of glucose metabolism under calcineurin inhibitors in the first year after renal transplantation in nonobese patients. | 2007 | Transplantation | pmid:17627237 |
| Ferraris JR et al. | Conversion from cyclosporine A to tacrolimus in pediatric kidney transplant recipients with chronic rejection: changes in the immune responses. | 2004 | Transplantation | pmid:15084930 |
| Reese JC et al. | The effect of FK506 on canine bile flow. | 1993 | Transplantation | pmid:7504342 |
| Shapiro R et al. | Posttransplant lymphoproliferative disorders in adult and pediatric renal transplant patients receiving tacrolimus-based immunosuppression. | 1999 | Transplantation | pmid:10628763 |
| Velidedeoglu E et al. | Early kidney dysfunction post liver transplantation predicts late chronic kidney disease. | 2004 | Transplantation | pmid:15084934 |
| Cox KL et al. | An increased incidence of Epstein-Barr virus infection and lymphoproliferative disorder in young children on FK506 after liver transplantation. | 1995 | Transplantation | pmid:7533344 |
| McDiarmid SV et al. | FK506 (tacrolimus) compared with cyclosporine for primary immunosuppression after pediatric liver transplantation. Results from the U.S. Multicenter Trial. | 1995 | Transplantation | pmid:7533345 |
| Roy A et al. | Tacrolimus as intervention in the treatment of hyperlipidemia after liver transplant. | 2006 | Transplantation | pmid:16926593 |
| Welberry Smith MP et al. | Alemtuzumab induction in renal transplantation permits safe steroid avoidance with tacrolimus monotherapy: a randomized controlled trial. | 2013 | Transplantation | pmid:24056618 |
| Savoldo B et al. | Generation of autologous Epstein-Barr virus-specific cytotoxic T cells for adoptive immunotherapy in solid organ transplant recipients. | 2001 | Transplantation | pmid:11579304 |
| Iyengar AR et al. | Striking augmentation of hematopoietic cell chimerism in noncytoablated allogeneic bone marrow recipients by FLT3 ligand and tacrolimus. | 1997 | Transplantation | pmid:9158008 |
| Hill CC et al. | Penile prosthesis surgery in the immunosuppressed patient. | 1993 | Transplantation | pmid:7692633 |
| Hariharan S et al. | Rescue therapy with tacrolimus after combined kidney/pancreas and isolated pancreas transplantation in patients with severe cyclosporine nephrotoxicity. | 1996 | Transplantation | pmid:8610411 |
| Xu X et al. | FKBP12 is the only FK506 binding protein mediating T-cell inhibition by the immunosuppressant FK506. | 2002 | Transplantation | pmid:12085010 |
| Zhao WY et al. | Single kidneys transplanted from small pediatric donors less than 15 kilograms into pediatric recipients. | 2014 | Transplantation | pmid:25955345 |
| Moreau C et al. | Interaction between tacrolimus and omeprazole in a pediatric liver transplant recipient. | 2006 | Transplantation | pmid:16477241 |
| Guerville F et al. | Transplantation with pathologic kidneys to improve the pool of donors: an example of shunt nephritis. | 2012 | Transplantation | pmid:22487813 |
| Swinnen LJ et al. | Prospective study of sequential reduction in immunosuppression, interferon alpha-2B, and chemotherapy for posttransplantation lymphoproliferative disorder. | 2008 | Transplantation | pmid:18645482 |
| Woodle ES et al. | FK506: inhibition of humoral mechanisms of hepatic allograft rejection. | 1992 | Transplantation | pmid:1379749 |
| Singla AK et al. | Cerulomycin Caerulomycin [corrected] A: a potent novel immunosuppressive agent. | 2014 | Transplantation | pmid:24949498 |
| Chapman WC et al. | Effect of Early Everolimus-Facilitated Reduction of Tacrolimus on Efficacy and Renal Function in De Novo Liver Transplant Recipients: 24-Month Results for the North American Subpopulation. | 2017 | Transplantation | pmid:28121741 |
| Homma M et al. | Effects of lansoprazole and rabeprazole on tacrolimus blood concentration: case of a renal transplant recipient with CYP2C19 gene mutation. | 2002 | Transplantation | pmid:11821750 |
| Walsh C et al. | Anti-CD25 monoclonal antibody replacement therapy for chronic kidney disease in liver transplant recipients. | 2013 | Transplantation | pmid:23296149 |
| Becker T et al. | Patient outcomes in two steroid-free regimens using tacrolimus monotherapy after daclizumab induction and tacrolimus with mycophenolate mofetil in liver transplantation. | 2008 | Transplantation | pmid:19104406 |
| Shapiro R et al. | "Suboptimal" kidney donors: the experience with tacrolimus-based immunosuppression. | 1996 | Transplantation | pmid:8932264 |
| Fisher NC et al. | The clinical impact of nephrotoxicity in liver transplantation. | 2000 | Transplantation | pmid:10910259 |
| Ko S et al. | The enhanced immunosuppressive efficacy of newly developed liposomal FK506 in canine liver transplantation. | 1995 | Transplantation | pmid:7539553 |
| Moffatt SD and Metcalfe SM | Comparison between tacrolimus and cyclosporine as immunosuppressive agents compatible with tolerance induction by CD4/CD8 blockade. | 2000 | Transplantation | pmid:10836388 |
| Garton T | Nefazodone and cyp450 3a4 interactions with cyclosporine and tacrolimus1. | 2002 | Transplantation | pmid:12352898 |
| Borni-Duval C et al. | Risk factors for BK virus infection in the era of therapeutic drug monitoring. | 2013 | Transplantation | pmid:23778568 |
| Anil Kumar MS et al. | Comparison of steroid avoidance in tacrolimus/mycophenolate mofetil and tacrolimus/sirolimus combination in kidney transplantation monitored by surveillance biopsy. | 2005 | Transplantation | pmid:16210969 |
| Jain A et al. | Long-term outcome of adding mycophenolate mofetil to tacrolimus for nephrotoxicity following liver transplantation. | 2005 | Transplantation | pmid:16210976 |
| Paterson DL et al. | Infectious complications occurring in liver transplant recipients receiving mycophenolate mofetil. | 1998 | Transplantation | pmid:9753337 |
| Mourer JS et al. | Late calcineurin inhibitor withdrawal prevents progressive left ventricular diastolic dysfunction in renal transplant recipients. | 2012 | Transplantation | pmid:22955227 |
| Florman S et al. | Once-daily tacrolimus extended release formulation: experience at 2 years postconversion from a Prograf-based regimen in stable liver transplant recipients. | 2007 | Transplantation | pmid:17589349 |
| Miao G et al. | Development of donor-specific immunoregulatory T-cells after local CTLA4Ig gene transfer to pancreatic allograft. | 2004 | Transplantation | pmid:15257039 |
| Webb NJ et al. | Corticosteroid-free Kidney Transplantation Improves Growth: 2-Year Follow-up of the TWIST Randomized Controlled Trial. | 2015 | Transplantation | pmid:25539467 |
| Yoo MC et al. | Steroid-free Liver Transplantation Using Rabbit Antithymocyte Globulin Induction in 500 Consecutive Patients. | 2015 | Transplantation | pmid:25539464 |
| Glotz D et al. | Thymoglobulin induction and sirolimus versus tacrolimus in kidney transplant recipients receiving mycophenolate mofetil and steroids. | 2010 | Transplantation | pmid:20386144 |
| Miura Y et al. | Factors increasing quantitative interstitial fibrosis from 0 hr to 1 year in living kidney transplant patients receiving tacrolimus. | 2011 | Transplantation | pmid:21452412 |
| Cezário ES et al. | Gingival overgrowth in renal transplant subjects medicated with tacrolimus in the absence of calcium channel blockers. | 2008 | Transplantation | pmid:18212628 |
| Rayar M et al. | High Intrapatient Variability of Tacrolimus Exposure in the Early Period After Liver Transplantation Is Associated With Poorer Outcomes. | 2018 | Transplantation | pmid:29315140 |
| Gillard P et al. | Comparison of sirolimus alone with sirolimus plus tacrolimus in type 1 diabetic recipients of cultured islet cell grafts. | 2008 | Transplantation | pmid:18212631 |
| Kuypers DR et al. | Clinically relevant drug interaction between voriconazole and tacrolimus in a primary renal allograft recipient. | 2006 | Transplantation | pmid:16794545 |
| Langrehr JM et al. | Clinical course, morphology, and treatment of chronically rejecting small bowel allografts. | 1993 | Transplantation | pmid:7679526 |