| MeSH term | MeSH ID | Detail |
|---|---|---|
| Autoimmune Diseases | D001327 | 27 associated lipids |
| Brain Diseases | D001927 | 27 associated lipids |
| Endotoxemia | D019446 | 27 associated lipids |
| Ventricular Remodeling | D020257 | 28 associated lipids |
| Obesity | D009765 | 29 associated lipids |
| Kidney Diseases | D007674 | 29 associated lipids |
| Catalepsy | D002375 | 30 associated lipids |
| Dermatitis | D003872 | 30 associated lipids |
| Drug Eruptions | D003875 | 30 associated lipids |
| Proteinuria | D011507 | 30 associated lipids |
tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Galat A | A note on circular-dichroic-constrained prediction of protein secondary structure. | 1996 | Eur. J. Biochem. | pmid:8612612 |
| Márquez JA and Serrano R | Multiple transduction pathways regulate the sodium-extrusion gene PMR2/ENA1 during salt stress in yeast. | 1996 | FEBS Lett. | pmid:8612770 |
| Stoller G et al. | An 11.8 kDa proteolytic fragment of the E. coli trigger factor represents the domain carrying the peptidyl-prolyl cis/trans isomerase activity. | 1996 | FEBS Lett. | pmid:8612805 |
| Pham SM et al. | A prospective trial of tacrolimus (FK 506) in clinical heart transplantation: intermediate-term results. | 1996 | J. Thorac. Cardiovasc. Surg. | pmid:8614136 |
| Tanaka M et al. | Tacrolimus (FK 506)-dependent tolerance after liver and heart xenotransplantation: inhibition of humoral response and acceptance of donor organs. | 1996 | Transplant. Proc. | pmid:8623341 |
| Ye Q et al. | Functional analysis of hamster kidney xenografts in the rat: possible functional incompatibility and adaptation of hamster kidney grafts in a xenogenic rat environment. | 1996 | Transplant. Proc. | pmid:8623350 |
| Namii Y et al. | Tetrahydropyranyladriamycin with FK 506 combination therapy for hamster-to-rat-concordant xenotransplantation. | 1996 | Transplant. Proc. | pmid:8623358 |
| Valdivia LA et al. | Prolonged survival of hearts obtained from chimeric donors in a mouse to rat xenotransplant model. | 1996 | Transplant. Proc. | pmid:8623371 |
| Wakizaka Y et al. | Xenotransplantation of hamster liver into Gunn rats reserves congenital hyperbilirubinemia. | 1996 | Transplant. Proc. | pmid:8623372 |
| Pan F et al. | Effect of tacrolimus and splenectomy on engraftment and GVHD after bone marrow xenotransplantation in the reciprocal hamster to rat animal models. | 1996 | Transplant. Proc. | pmid:8623373 |
| Fukushima N et al. | Histological findings in heart grafts after orthotopic pig to baboon cardiac transplantation. | 1996 | Transplant. Proc. | pmid:8623400 |
| Takeda M et al. | Methotrexate in rescue therapy for xenotransplanted lungs in primates. | 1996 | Transplant. Proc. | pmid:8623402 |
| Fehr T et al. | Antascomicins A, B, C, D and E. Novel FKBP12 binding compounds from a Micromonospora strain. | 1996 | J. Antibiot. | pmid:8626235 |
| Zhang BW et al. | T cell responses in calcineurin A alpha-deficient mice. | 1996 | J. Exp. Med. | pmid:8627154 |
| Dragovich PS et al. | Structure-based design of novel, urea-containing FKBP12 inhibitors. | 1996 | J. Med. Chem. | pmid:8627611 |
| Mori A et al. | Enhanced production and gene expression of IL-5 in bronchial asthma. Possible management of atopic diseases with IL-5 specific gene transcription inhibitor. | 1996 | Adv. Exp. Med. Biol. | pmid:9095279 |
| Eberhard OK et al. | How best to use tacrolimus (FK506) for treatment of steroid- and OKT3-resistant rejection after renal transplantation. | 1996 | Transplantation | pmid:8629294 |
| Millis JM et al. | Tacrolimus for primary treatment of steroid-resistant hepatic allograft rejection. | 1996 | Transplantation | pmid:8629298 |
| Systemic tacrolimus (FK 506) is effective for the treatment of psoriasis in a double-blind, placebo-controlled study. The European FK 506 Multicentre Psoriasis Study Group. | 1996 | Arch Dermatol | pmid:8629845 | |
| DiGiuseppe JA et al. | Tacrolimus-related posttransplant lymphoproliferative disorder presenting as autoimmune hemolytic anemia. | 1996 | Arch. Pathol. Lab. Med. | pmid:8629906 |
| Li W and Handschumacher RE | Regulation of the nuclear factor of activated T cells in stably transfected Jurkat cell clones. | 1996 | Biochem. Biophys. Res. Commun. | pmid:8619834 |
| Yanchar NL et al. | Tacrolimus (FK506)--its effects on intestinal glucose transport. | 1996 | Transplantation | pmid:8610392 |
| Hariharan S et al. | Rescue therapy with tacrolimus after combined kidney/pancreas and isolated pancreas transplantation in patients with severe cyclosporine nephrotoxicity. | 1996 | Transplantation | pmid:8610411 |
| Cacciarelli TV et al. | Oral tacrolimus (FK506) induction therapy in pediatric orthotopic liver transplantation. | 1996 | Transplantation | pmid:8610416 |
| Osowski CL et al. | Evaluation of the drug interaction between intravenous high-dose fluconazole and cyclosporine or tacrolimus in bone marrow transplant patients. | 1996 | Transplantation | pmid:8610430 |
| Tanida I et al. | Yeast Cls2p/Csg2p localized on the endoplasmic reticulum membrane regulates a non-exchangeable intracellular Ca2+ pool cooperatively with calcineurin. | 1996 | FEBS Lett. | pmid:8566225 |
| Michel G et al. | FK506 in the treatment of inflammatory skin disease: promises and perspectives. | 1996 | Immunol. Today | pmid:8820265 |
| Boeve BF et al. | Dysarthria and apraxia of speech associated with FK-506 (tacrolimus). | 1996 | Mayo Clin. Proc. | pmid:8820772 |
| Platz KP et al. | Immunosuppressive power and limitations of FK 506 for prevention and treatment of graft-vs-host disease after small bowel transplantation. | 1996 | Transplant. Proc. | pmid:8907933 |
| Komatsu K et al. | Prolonged survival of hamster-to-rat pulmonary xenografts by tacrolimus (FK506) and cyclophosphamide. | 1996 | J. Heart Lung Transplant. | pmid:8820789 |
| Velio P et al. | Rejection and survival after total orthotopic liver-small bowel allotransplantation in pigs immunosuppressed with FK 506. | 1996 | Transplant. Proc. | pmid:8907936 |
| Bardella MT et al. | FK 506 and cyclosporine: effect on D-xylose absorption in pigs with orthotopic liver-small bowel allotransplants. | 1996 | Transplant. Proc. | pmid:8907937 |
| Hayashi K et al. | Suppression of experimental crescentic-type anti-glomerular basement membrane (GBM) nephritis by FK506 (tacrolimus hydrate) in rats. | 1996 | Jpn. J. Pharmacol. | pmid:8822088 |
| Sugitani A et al. | Intestinal neurons in acute and chronic rejection after small bowel transplantation in dogs. | 1996 | Transplant. Proc. | pmid:8907941 |
| Sasahara Y et al. | Okadaic acid suppresses neural differentiation-dependent expression of the neurofilament-L gene in P19 embryonal carcinoma cells by post-transcriptional modification. | 1996 | J. Biol. Chem. | pmid:8824230 |
| Ronchetti F et al. | Mucosal hyaluronic acid quantification in small bowel transplantation in pigs. | 1996 | Transplant. Proc. | pmid:8907950 |
| Lang T et al. | Production of IL-4 and IL-10 does not lead to immune quiescence in vascularized human organ grafts. | 1996 | Transplantation | pmid:8824477 |
| Costa A et al. | Stimulatory effect of FK506 and erythromycin on pig intestinal motility. | 1996 | Transplant. Proc. | pmid:8907957 |
| Matsuda H et al. | Interactions of FK506 (tacrolimus) with clinically important drugs. | 1996 | Res. Commun. Mol. Pathol. Pharmacol. | pmid:8824931 |
| Cicalese L et al. | Effect of FK506 on the mucosal perfusion of the rat intestinal allograft. | 1996 | Transplant. Proc. | pmid:8907959 |
| Reggiani P et al. | Oral administration of FK 506 in a swine model of liver-small bowel allotransplantation. | 1996 | Transplant. Proc. | pmid:8907965 |
| Licitra EJ and Liu JO | A three-hybrid system for detecting small ligand-protein receptor interactions. | 1996 | Proc. Natl. Acad. Sci. U.S.A. | pmid:8917502 |
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| Ikebe S et al. | Immunosuppressive effect of tacrolimus (FK-506). Bone xenografts in rabbits. | 1996 | Acta Orthop Scand | pmid:8792745 |
| Masaki Y et al. | Microchimerism and rat small bowel transplantation combined with donor-type bone marrow cells. | 1996 | Transplant. Proc. | pmid:8769154 |
| Mollison KW et al. | Discovery of FK 506 analogues that are nontoxic to mouse pancreatic beta cells in vitro but show diabetogenic potential when administered to the rat. | 1996 | Transplant. Proc. | pmid:8962236 |
| Jordan ML et al. | Tacrolimus rescue therapy for renal transplant rejection. | 1996 | Transplant. Proc. | pmid:8769174 |
| Yokoyama I et al. | Decreased Fas antigen expression of cultured hepatocytes with FK 506. | 1996 | Transplant. Proc. | pmid:8962237 |
| Baruch Y et al. | Anasarca and hypertrophic cardiomyopathy in a liver transplant patient on FK506: relieved after a switch to Neoral. | 1996 | Transplant. Proc. | pmid:8769215 |
| Mueller AR et al. | Long-term follow-up in hepatitis C patients with respect to immunosuppression. | 1996 | Transplant. Proc. | pmid:8962255 |
| Melter M et al. | Successful reconversion from tacrolimus to cyclosporine A Neoral in pediatric liver recipients. | 1996 | Transplant. Proc. | pmid:8769224 |
| Jonas S et al. | Posttransplant malignancy and newer immunosuppressive protocols after liver transplantation. | 1996 | Transplant. Proc. | pmid:8962257 |
| Tanaka M et al. | Reduction of immunosuppressive agents after living related donor liver transplantation. | 1996 | Transplant. Proc. | pmid:8769268 |
| Randhawa PS et al. | Microvascular changes in renal allografts associated with FK506 (Tacrolimus) therapy. | 1996 | Am. J. Surg. Pathol. | pmid:8772784 |
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| Chen BG et al. | Inhibition by CsA and FK506 of the in vitro proliferative response of gamma delta T cells on stimulation with anti-TCR delta monoclonal antibody. | 1996 | Transpl. Immunol. | pmid:8843593 |
| Andrews PA et al. | Racial variation in dosage requirements of tacrolimus. | 1996 | Lancet | pmid:8937292 |
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| Eckert B et al. | Calcium-mobilizing insulin secretagogues stimulate transcription that is directed by the cyclic adenosine 3',5'-monophosphate/calcium response element in a pancreatic islet beta-cell line. | 1996 | Endocrinology | pmid:8536617 |
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