| MeSH term | MeSH ID | Detail |
|---|---|---|
| Cardiomegaly | D006332 | 31 associated lipids |
| Liver Diseases | D008107 | 31 associated lipids |
| Neurodegenerative Diseases | D019636 | 32 associated lipids |
| Diarrhea | D003967 | 32 associated lipids |
| Stroke | D020521 | 32 associated lipids |
| Ventricular Dysfunction, Left | D018487 | 33 associated lipids |
| Memory Disorders | D008569 | 33 associated lipids |
| Peripheral Nervous System Diseases | D010523 | 33 associated lipids |
| Uremia | D014511 | 33 associated lipids |
| Spinal Cord Injuries | D013119 | 34 associated lipids |
tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (2)
- Am. J. Physiol. Renal Physiol. (1)
- Drug Metab. Dispos. (1)
- Others (1)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Senatorski G et al. | [New immune suppressants: topical immunomodulatory agents]. | 2002 | Prz. Lek. | pmid:12715720 |
| Fujine K et al. | FR252921, a novel immunosuppressive agent isolated from Pseudomonas fluorescens no. 408813 III. In vivo activities. | 2003 | J. Antibiot. | pmid:12715863 |
| Nakamura Y et al. | Acceptance of islet allografts in the liver of mice by blockade of an inducible costimulator. | 2003 | Transplantation | pmid:12717187 |
| Qi S et al. | Significant prolongation of renal allograft survival by delayed combination therapy of FK778 with tacrolimus in nonhuman primates. | 2003 | Transplantation | pmid:12717189 |
| Haririan A et al. | Polyomavirus reactivation in native kidneys of pancreas alone allograft recipients. | 2003 | Transplantation | pmid:12717201 |
| Gonwa T et al. | Randomized trial of tacrolimus in combination with sirolimus or mycophenolate mofetil in kidney transplantation: results at 6 months. | 2003 | Transplantation | pmid:12717205 |
| Tzakis AG et al. | Preliminary experience with campath 1H (C1H) in intestinal and liver transplantation. | 2003 | Transplantation | pmid:12717207 |
| Dresske B et al. | WOFIE synergizes with calcineurin-inhibitor treatment and early steroid withdrawal in kidney transplantation. | 2003 | Transplantation | pmid:12717217 |
| Eason JD et al. | Steroid-free liver transplantation using rabbit antithymocyte globulin and early tacrolimus monotherapy. | 2003 | Transplantation | pmid:12717237 |
| Stütz A et al. | [Development and pre-clinical aspects of pimecrolimus]. | 2003 | Hautarzt | pmid:12719859 |
| Ständer S and Luger TA | [Antipruritic effects of pimecrolimus and tacrolimus]. | 2003 | Hautarzt | pmid:12719860 |
| Thaçi D | [Long term management of childhood atopic dermatitis with calcineurin inhibitors]. | 2003 | Hautarzt | pmid:12719861 |
| Meurer M and Wozel G | [The treatment of atopic dermatitis in adults with topical calcineurin inhibitors]. | 2003 | Hautarzt | pmid:12719862 |
| Lübbe J | [Practice experience with topical calcineurin inhibitors]. | 2003 | Hautarzt | pmid:12719863 |
| Quatresooz P et al. | [Medication of the month. Topical pimecrolimus (Elidel)]. | 2003 | Rev Med Liege | pmid:12723511 |
| Schneider BL et al. | Prevention of the initial host immuno-inflammatory response determines the long-term survival of encapsulated myoblasts genetically engineered for erythropoietin delivery. | 2003 | Mol. Ther. | pmid:12727114 |
| Akamaru Y et al. | Ex vivo and systemic transfer of adenovirus-mediated CTLA4Ig gene combined with a short course of FK506 therapy prolongs islet graft survival. | 2003 Jan-Mar | Transpl. Immunol. | pmid:12727480 |
| Meller R et al. | Seizure-like activity leads to the release of BAD from 14-3-3 protein and cell death in hippocampal neurons in vitro. | 2003 | Cell Death Differ. | pmid:12728252 |
| Antin JH et al. | Sirolimus, tacrolimus, and low-dose methotrexate for graft-versus-host disease prophylaxis in mismatched related donor or unrelated donor transplantation. | 2003 | Blood | pmid:12730113 |
| Rustin M | Tacrolimus ointment for the management of atopic dermatitis. | 2003 | Hosp Med | pmid:12731133 |
| Lanzetta M et al. | Effect of FK506 and basic fibroblast growth factor on nerve regeneration using a polytetrafluoroethylene chamber for nerve repair. | 2003 Jan-Mar | Int Surg | pmid:12731731 |
| Mahakunakorn P et al. | Cytoprotective and cytotoxic effects of curcumin: dual action on H2O2-induced oxidative cell damage in NG108-15 cells. | 2003 | Biol. Pharm. Bull. | pmid:12736521 |
| Bjøro K et al. | Secondary osteoporosis in liver transplant recipients: a longitudinal study in patients with and without cholestatic liver disease. | 2003 | Scand. J. Gastroenterol. | pmid:12737449 |
| Claas FH | Towards clinical transplantation tolerance. | 2003 | Lancet | pmid:12737855 |
| Starzl TE et al. | Tolerogenic immunosuppression for organ transplantation. | 2003 | Lancet | pmid:12737859 |
| Lotery HE and Galask RP | Erosive lichen planus of the vulva and vagina. | 2003 | Obstet Gynecol | pmid:12738123 |
| Burke GW | Foreword. | 2003 | Nephrol. Dial. Transplant. | pmid:12738755 |
| First MR | Renal function as a predictor of long-term graft survival in renal transplant patients. | 2003 | Nephrol. Dial. Transplant. | pmid:12738756 |
| Jurewicz WA | Tacrolimus versus cyclosporin immunosuppression: long-term outcome in renal transplantation. | 2003 | Nephrol. Dial. Transplant. | pmid:12738757 |
| Undre NA | Pharmacokinetics of tacrolimus-based combination therapies. | 2003 | Nephrol. Dial. Transplant. | pmid:12738758 |
| Yang HC | Tailoring tacrolimus-based immunotherapy in renal transplantation. | 2003 | Nephrol. Dial. Transplant. | pmid:12738759 |
| Parrilli G et al. | Effect of chronic administration of tacrolimus and cyclosporine on human gastrointestinal permeability. | 2003 | Liver Transpl. | pmid:12740791 |
| Jiang W et al. | Synergistic effect of vincristine with tacrolimus or sirolimus in prevention of acute heart allograft rejection in the rat. | 2003 | Microsurgery | pmid:12740883 |
| Gerbase MW et al. | Pharmacokinetics of mycophenolic acid associated with calcineurin inhibitors: long-term monitoring in stable lung recipients with and without cystic fibrosis. | 2003 | J. Heart Lung Transplant. | pmid:12742423 |
| Calne RY | The development of immunosuppression: the rapamycin milestone. | 2003 | Transplant. Proc. | pmid:12742463 |
| El-Sabrout R et al. | Sirolimus in combination with tacrolimus or mycophenolate mofetil for minimizing acute rejection risk in renal transplant recipients--a single center experience. | 2003 | Transplant. Proc. | pmid:12742474 |
| Formica RN et al. | Sirolimus-based immunosuppression with reduce dose cyclosporine or tacrolimus after renal transplantation. | 2003 | Transplant. Proc. | pmid:12742475 |
| Lo A et al. | Observations on the use of sirolimus and tacrolimus in high-risk renal transplant recipients. | 2003 | Transplant. Proc. | pmid:12742477 |
| Russ GR et al. | Reduced and standard target concentration tacrolimus with sirolimus in renal allograft recipients. | 2003 | Transplant. Proc. | pmid:12742480 |
| Flechner SM | Minimizing calcineurin inhibitor drugs in renal transplantation. | 2003 | Transplant. Proc. | pmid:12742481 |
| Wiseman AC et al. | Fixed-dose sirolimus with reduced dose calcineurin inhibitor: the University of Colorado experience. | 2003 | Transplant. Proc. | pmid:12742482 |
| Holt DW et al. | Therapeutic monitoring of sirolimus: its contribution to optimal prescription. | 2003 | Transplant. Proc. | pmid:12742490 |
| Trotter JF | Sirolimus in liver transplantation. | 2003 | Transplant. Proc. | pmid:12742496 |
| MacDonald AS | Rapamycin in combination with cyclosporine or tacrolimus in liver, pancreas, and kidney transplantation. | 2003 | Transplant. Proc. | pmid:12742497 |
| Neff GW et al. | Ten years of sirolimus therapy in orthotopic liver transplant recipients. | 2003 | Transplant. Proc. | pmid:12742498 |
| Eichenfield LF and Beck L | Elidel (pimecrolimus) cream 1%: a nonsteroidal topical agent for the treatment of atopic dermatitis. | 2003 | J. Allergy Clin. Immunol. | pmid:12743593 |
| Hubler TR et al. | The FK506-binding immunophilin FKBP51 is transcriptionally regulated by progestin and attenuates progestin responsiveness. | 2003 | Endocrinology | pmid:12746298 |
| Merlino C et al. | [Epstein Barr viral load monitoring in mononuclear lymphocytes and serum of renal transplant recipients using a quantitative PCR protocol]. | 2003 Mar-Apr | G Ital Nefrol | pmid:12746803 |
| Bunetel L et al. | An unusual oral chronic graft-versus-host disease-like syndrome following a liver transplant. | 2003 | J. Periodontol. | pmid:12747462 |
| Mengel M et al. | Incidence of polyomavirus-nephropathy in renal allografts: influence of modern immunosuppressive drugs. | 2003 | Nephrol. Dial. Transplant. | pmid:12748354 |
| Moons P et al. | Health-related quality of life and symptom experience in tacrolimus-based regimens after renal transplantation: a multicentre study. | 2003 | Transpl. Int. | pmid:12748758 |
| Wencker D et al. | A mechanistic role for cardiac myocyte apoptosis in heart failure. | 2003 | J. Clin. Invest. | pmid:12750399 |
| Mcauliffe EP | Is tacrolimus the best therapy for atopic dermatitis? | 2003 | Am Fam Physician | pmid:12751651 |
| Chambers CA | Topical tacrolimus for cutaneous lupus erythematosus. | 2003 | Br. J. Dermatol. | pmid:12752154 |
| Vecchietti G et al. | Topical tacrolimus (FK506) for relapsing erosive stomatitis in paraneoplastic pemphigus. | 2003 | Br. J. Dermatol. | pmid:12752158 |
| Woodward RS et al. | Incidence and cost of new onset diabetes mellitus among U.S. wait-listed and transplanted renal allograft recipients. | 2003 | Am. J. Transplant. | pmid:12752315 |
| Reid DW et al. | Microangiopathic haemolytic anaemia and thrombocytopenia following lung volume reduction surgery in a single lung transplant recipient on maintenance tacrolimus (FK506) therapy. | 2003 | Respirology | pmid:12753543 |
| Baumgart DC et al. | Rescue therapy with tacrolimus is effective in patients with severe and refractory inflammatory bowel disease. | 2003 | Aliment. Pharmacol. Ther. | pmid:12755840 |
| Neu AM et al. | Tacrolimus vs. cyclosporine A as primary immunosuppression in pediatric renal transplantation: a NAPRTCS study. | 2003 | Pediatr Transplant | pmid:12756047 |
| Rajwal SR et al. | Use of basiliximab in pediatric liver transplantation for Langerhans cell histiocytosis. | 2003 | Pediatr Transplant | pmid:12756053 |
| Travis LB et al. | Successful treatment of vitiligo with 0.1% tacrolimus ointment. | 2003 | Arch Dermatol | pmid:12756092 |
| Lepe V et al. | A double-blind randomized trial of 0.1% tacrolimus vs 0.05% clobetasol for the treatment of childhood vitiligo. | 2003 | Arch Dermatol | pmid:12756094 |
| Plettenberg H et al. | Childhood vitiligo and tacrolimus: immunomodulating treatment for an autoimmune disease. | 2003 | Arch Dermatol | pmid:12756103 |
| Lübbe J et al. | Adults with atopic dermatitis and herpes simplex and topical therapy with tacrolimus: what kind of prevention? | 2003 | Arch Dermatol | pmid:12756112 |
| Oetjen E et al. | Inhibition of human insulin gene transcription by the immunosuppressive drugs cyclosporin A and tacrolimus in primary, mature islets of transgenic mice. | 2003 | Mol. Pharmacol. | pmid:12761338 |
| Waechter F | Drug company accused of breaking advertising regulations. | 2003 | BMJ | pmid:12763970 |
| Taylor PJ and Morris RG | Tacrolimus measurement by microparticle enzyme immunoassay II. | 2003 | Ther Drug Monit | pmid:12766549 |
| Beppu K et al. | Inhibition of interferon-gamma-activated nuclear factor-kappa B by cyclosporin A: A possible mechanism for synergistic induction of apoptosis by interferon-gamma and cyclosporin A in gastric carcinoma cells. | 2003 | Biochem. Biophys. Res. Commun. | pmid:12767900 |
| Elad S et al. | Topical tacrolimus--a novel treatment alternative for cutaneous chronic graft-versus-host disease. | 2003 | Transpl. Int. | pmid:12768230 |
| Klettner A and Herdegen T | FK506 and its analogs - therapeutic potential for neurological disorders. | 2003 | Curr Drug Targets CNS Neurol Disord | pmid:12769796 |
| New treatment options for atopic dermatitis. | 2003 | Mayo Clin Health Lett | pmid:12772683 | |
| French AE et al. | Milk transfer and neonatal safety of tacrolimus. | 2003 | Ann Pharmacother | pmid:12773068 |
| Charpentier B | Tacrolimus in renal transplantation. A review of recent data. | 2003 | Minerva Urol Nefrol | pmid:12773964 |
| van Duijnhoven EM et al. | Metabolic aspects of tacrolimus in renal transplantation. Consequences for the choice of an immunosuppressive regimen and for the management of post-transplant diabetes mellitus. | 2003 | Minerva Urol Nefrol | pmid:12773965 |
| Kang S et al. | Safe treatment of head/neck AD with tacrolimus ointment. | 2003 | J Dermatolog Treat | pmid:12775315 |
| Diem HV et al. | Pediatric liver transplantation for biliary atresia: results of primary grafts in 328 recipients. | 2003 | Transplantation | pmid:12777858 |
| Torres A et al. | [Bone metabolism alterations after kidney transplantation]. | 2003 | Nefrologia | pmid:12778868 |
| Pirenne J et al. | Steroid-free immunosuppression during and after liver transplantation--a 3-yr follow-up report. | 2003 | Clin Transplant | pmid:12780665 |
| Hathaway D et al. | The first report from the patient outcomes registry for transplant effects on life (PORTEL): differences in side-effects and quality of life by organ type, time since transplant and immunosuppressive regimens. | 2003 | Clin Transplant | pmid:12780666 |
| Oflaz H et al. | The effect of calcineurin inhibitors on endothelial function in renal transplant recipients. | 2003 | Clin Transplant | pmid:12780670 |
| Kuypers DR et al. | The use of an anti-CD25 monoclonal antibody and mycophenolate mofetil enables the use of a low-dose tacrolimus and early withdrawal of steroids in renal transplant recipients. | 2003 | Clin Transplant | pmid:12780674 |
| Berengue JI et al. | Two- to three-fold increase in blood tacrolimus (FK506) levels during diarrhea in liver-transplanted children. | 2003 | Clin Transplant | pmid:12780676 |
| Tomi NS and Luger TA | The treatment of atopic dermatitis with topical immunomodulators. | 2003 May-Jun | Clin. Dermatol. | pmid:12781439 |
| Greig P et al. | Early steroid withdrawal after liver transplantation: the Canadian tacrolimus versus microemulsion cyclosporin A trial: 1-year follow-up. | 2003 | Liver Transpl. | pmid:12783400 |
| Arnette D et al. | Regulation of ERK1 and ERK2 by glucose and peptide hormones in pancreatic beta cells. | 2003 | J. Biol. Chem. | pmid:12783880 |
| Pascu M et al. | Rescue therapy with tacrolimus in a patient with toxic megacolon. | 2003 | Int J Colorectal Dis | pmid:12785330 |
| Courjaret R et al. | Two distinct calcium-sensitive and -insensitive PKC up- and down-regulate an alpha-bungarotoxin-resistant nAChR1 in insect neurosecretory cells (DUM neurons). | 2003 | Eur. J. Neurosci. | pmid:12786968 |
| Ferrand-Drake M et al. | Cyclosporin A prevents calpain activation despite increased intracellular calcium concentrations, as well as translocation of apoptosis-inducing factor, cytochrome c and caspase-3 activation in neurons exposed to transient hypoglycemia. | 2003 | J. Neurochem. | pmid:12787063 |
| Assmann T et al. | Tacrolimus ointment for the treatment of vulvar lichen sclerosus. | 2003 | J. Am. Acad. Dermatol. | pmid:12789187 |
| Schroer B and Lockey R | Oral tacrolimus for severe recalcitrant atopic eczema. | 2003 | J. Allergy Clin. Immunol. | pmid:12789248 |
| Pimecrolimus cream for atopic dermatitis. | 2003 | Drug Ther Bull | pmid:12789846 | |
| Scott LJ et al. | Tacrolimus: a further update of its use in the management of organ transplantation. | 2003 | Drugs | pmid:12790696 |
| King-Biggs MB et al. | Airway anastomotic dehiscence associated with use of sirolimus immediately after lung transplantation. | 2003 | Transplantation | pmid:12792493 |
| Vu MD et al. | Combination therapy of malononitrilamide FK778 with tacrolimus on cell proliferation assays and in rats receiving renal allografts. | 2003 | Transplantation | pmid:12792496 |
| Tzakis AG et al. | Alemtuzumab (Campath-1H) combined with tacrolimus in intestinal and multivisceral transplantation. | 2003 | Transplantation | pmid:12792506 |
| Koenen HJ et al. | Superior T-cell suppression by rapamycin and FK506 over rapamycin and cyclosporine A because of abrogated cytotoxic T-lymphocyte induction, impaired memory responses, and persistent apoptosis. | 2003 | Transplantation | pmid:12792519 |
| Hasegawa S et al. | Combination use of suboptimal dose of FK 506 and cyclosporine in canine lung transplantation. | 1992 | J. Thorac. Cardiovasc. Surg. | pmid:1279319 |
| Wilasrusmee C et al. | Morphological and biochemical effects of immunosuppressive drugs in a capillary tube assay for endothelial dysfunction. | 2003 | Clin Transplant | pmid:12795661 |
| Shaffer D et al. | A pilot protocol of a calcineurin-inhibitor free regimen for kidney transplant recipients of marginal donor kidneys or with delayed graft function. | 2003 | Clin Transplant | pmid:12795665 |
| Stratta RJ et al. | Long-term experience with simultaneous kidney-pancreas transplantation with portal-enteric drainage and tacrolimus/mycophenolate mofetil-based immunosuppression. | 2003 | Clin Transplant | pmid:12795673 |