tacrolimus

Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.

Cross Reference

Introduction

To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with tacrolimus?

tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with tacrolimus

MeSH term MeSH ID Detail
Intertrigo D007402 1 associated lipids
Impetigo D007169 3 associated lipids
Nocturnal Myoclonus Syndrome D020189 1 associated lipids
Pterygium D011625 3 associated lipids
Amyloid Neuropathies D017772 1 associated lipids
Mucinoses D017520 2 associated lipids
Carcinoma, Merkel Cell D015266 2 associated lipids
Nocturia D053158 1 associated lipids
Failed Back Surgery Syndrome D055111 3 associated lipids
Malacoplakia D008287 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with tacrolimus

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with tacrolimus?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with tacrolimus?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with tacrolimus?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with tacrolimus?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with tacrolimus?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with tacrolimus

Download all related citations
Per page 10 20 50 100 | Total 15051
Authors Title Published Journal PubMed Link
Carcas-Sansuán AJ Limited sampling strategies for once daily tacrolimus exposure monitoring. 2016 Eur. J. Clin. Pharmacol. pmid:26939899
Hazama Y et al. Effect of Physiological Changes in the Skin on Systemic Absorption of Tacrolimus Following Topical Application in Rats. 2016 Biol. Pharm. Bull. pmid:26934927
Iguchi A et al. Graft-versus-host disease (GVHD) prophylaxis by using methotrexate decreases pre-engraftment syndrome and severe acute GVHD, and accelerates engraftment after cord blood transplantation. 2016 Pediatr Transplant pmid:26526424
Fukuta T et al. Non-invasive evaluation of neuroprotective drug candidates for cerebral infarction by PET imaging of mitochondrial complex-I activity. 2016 Sci Rep pmid:27440054
Dugast E et al. Failure of Calcineurin Inhibitor (Tacrolimus) Weaning Randomized Trial in Long-Term Stable Kidney Transplant Recipients. 2016 Am. J. Transplant. pmid:27367750
Lim SW et al. Effect of Exendin-4 on Autophagy Clearance in Beta Cell of Rats with Tacrolimus-induced Diabetes Mellitus. 2016 Sci Rep pmid:27436514
Arreola-Guerra JM et al. Tacrolimus Trough Levels as a Risk Factor for Acute Rejection in Renal Transplant Patients. 2016 Ann. Transplant. pmid:26879833
Nie F et al. [Post-transplant kidney from C-III donation after cardiac death of children: a clinicopathologic study of 20 cases]. 2016 Zhonghua Bing Li Xue Za Zhi pmid:26879429
Dharnidharka VR et al. Differential risks for adverse outcomes 3 years after kidney transplantation based on initial immunosuppression regimen: a national study. 2016 Transpl. Int. pmid:27564782
Rostaing L et al. Successful Transplantation in ABO- and HLA-Incompatible Living Kidney Transplant Patients: A Report on 12 Cases. 2016 Ther Apher Dial pmid:27073167
Armand P et al. The addition of sirolimus to the graft-versus-host disease prophylaxis regimen in reduced intensity allogeneic stem cell transplantation for lymphoma: a multicentre randomized trial. 2016 Br. J. Haematol. pmid:26729448
Hanaoka K et al. A chronic renal rejection model with a fully MHC-mismatched rat strain combination under immunosuppressive therapy. 2016 Transpl. Immunol. pmid:27545900
Matsa E et al. Transcriptome Profiling of Patient-Specific Human iPSC-Cardiomyocytes Predicts Individual Drug Safety and Efficacy Responses In Vitro. 2016 Cell Stem Cell pmid:27545504
Mokuda S and Oiwa H Successful treatment of FKBP51-expressed multicentric reticulohistiocytosis using combination therapy with low-dose denosumab and tacrolimus. 2016 Scand. J. Rheumatol. pmid:26652057
Yu H et al. Risk factors for new-onset diabetes mellitus after living donor kidney transplantation in Korea - a retrospective single center study. 2016 BMC Nephrol pmid:27473469
Scalea JR et al. Tacrolimus for the prevention and treatment of rejection of solid organ transplants. 2016 Expert Rev Clin Immunol pmid:26588770
Sakai R et al. A comparison of tacrolimus and cyclosporine combined with methotrexate for graft-versus-host disease prophylaxis, stratified by stem cell source: a retrospective nationwide survey. 2016 Int. J. Hematol. pmid:26800676
Milgrom SA et al. Graft-versus-host disease after radiation therapy in patients who have undergone allogeneic stem cell transplantation: two case reports. 2016 J Med Case Rep pmid:27465468
Pouché L et al. New challenges and promises in solid organ transplantation pharmacogenetics: the genetic variability of proteins involved in the pharmacodynamics of immunosuppressive drugs. 2016 Pharmacogenomics pmid:26799749
Constantinescu AA et al. Differential influence of tacrolimus and sirolimus on mitochondrial-dependent signaling for apoptosis in pancreatic cells. 2016 Mol. Cell. Biochem. pmid:27344165
Shao K et al. Different Effects of Tacrolimus on Innate and Adaptive Immune Cells in the Allograft Transplantation. 2016 Scand. J. Immunol. pmid:26524694
Cena T et al. De novo noncutaneous malignancies after kidney transplantation are associated with an increased risk of graft failure: results from a time-dependent analysis on 672 patients. 2016 Transpl. Int. pmid:27343849
Binkhathlan Z et al. Reutilization of Tacrolimus Extracted from Expired Prograf® Capsules: Physical, Chemical, and Pharmacological Assessment. 2016 AAPS PharmSciTech pmid:26729529
Chacon A and Mercer J Successful management of angiolymphoid hyperplasia with eosinophilia in a split-face trial of topical tacrolimus and timolol solution. 2016 G Ital Dermatol Venereol pmid:25014586
Fernández de Castillo Torras L et al. Treatment with ulipristal acetate (Esmya(®)) and plasma levels of tacrolimus: a case report. 2016 Eur. J. Obstet. Gynecol. Reprod. Biol. pmid:27282803
Ferjani H et al. The evaluate and compare the effects of the Tacrolimus and Sirolimus on the intestinal system using an intestinal cell culture model. 2016 Toxicol. Mech. Methods pmid:26460985
Serrano-Mollar A et al. Safety and Tolerability of Alveolar Type II Cell Transplantation in Idiopathic Pulmonary Fibrosis. 2016 Chest pmid:27020420
Nerattini F et al. II. Dissociation free energies in drug-receptor systems via nonequilibrium alchemical simulations: application to the FK506-related immunophilin ligands. 2016 Phys Chem Chem Phys pmid:27193181
Seok J et al. Recalcitrant steroid-induced rosacea successfully treated with 0.03% tacrolimus and 595-nm pulsed dye laser. 2016 Eur J Dermatol pmid:27193042
Sisti A et al. Effectiveness and safety of topical tacrolimus monotherapy for repigmentation in vitiligo: a comprehensive literature review. 2016 An Bras Dermatol pmid:27192518
Rao B et al. Use of Everolimus After Multivisceral Transplantation: A Report of Two Cases. 2016 Transplant. Proc. pmid:27109983
Chang HK et al. Ten-Year Experience With Bowel Transplantation at Seoul St. Mary's Hospital. 2016 Transplant. Proc. pmid:27109981
Felix MJ et al. Time-Dependent and Immunosuppressive Drug-Associated Adverse Event Profiles in De Novo Kidney Transplant Recipients Converted from Tacrolimus to Sirolimus Regimens. 2016 Pharmacotherapy pmid:26799522
Kishida N et al. Increased Incidence of Thrombotic Microangiopathy After ABO-Incompatible Living Donor Liver Transplantation. 2016 Ann. Transplant. pmid:27956735
Jimbo H et al. Telangiectatic lichen sclerosus on the cheek successfully treated with topical tacrolimus. 2016 Eur J Dermatol pmid:27033557
Shimizu K et al. Specific delivery of an immunosuppressive drug to splenic B cells by antigen-modified liposomes and its antiallergic effect. 2016 J Drug Target pmid:27030163
Yan Y et al. Robust Axonal Regeneration in a Mouse Vascularized Composite Allotransplant Model Undergoing Delayed Tissue Rejection. 2016 Hand (N Y) pmid:28149214
Ha DH et al. Potential differentiation ability of gingiva originated human mesenchymal stem cell in the presence of tacrolimus. 2016 Sci Rep pmid:27721434
Thomusch O et al. Rabbit-ATG or basiliximab induction for rapid steroid withdrawal after renal transplantation (Harmony): an open-label, multicentre, randomised controlled trial. 2016 Lancet pmid:27871759
Koreth J et al. A Bortezomib-Based Regimen Offers Promising Survival and Graft-versus-Host Disease Prophylaxis in Myeloablative HLA-Mismatched and Unrelated Donor Transplantation: A Phase II Trial. 2015 Biol. Blood Marrow Transplant. pmid:26055298
Cheng S and Rodier F Manipulating senescence in health and disease: emerging tools. 2015 Cell Cycle pmid:25928330
Falloon K et al. Characterization of the FKBP12-Encoding Genes in Aspergillus fumigatus. 2015 PLoS ONE pmid:26366742
Nashan B et al. Evaluating the efficacy, safety and evolution of renal function with early initiation of everolimus-facilitated tacrolimus reduction in de novo liver transplant recipients: Study protocol for a randomized controlled trial. 2015 Trials pmid:25873064
Hlavaty KA et al. Cellular and molecular targeting for nanotherapeutics in transplantation tolerance. 2015 Clin. Immunol. pmid:25805659
Garritsen FM et al. Ten years experience with oral immunosuppressive treatment in adult patients with atopic dermatitis in two academic centres. 2015 J Eur Acad Dermatol Venereol pmid:25752497
Tachibana T et al. Successful Engraftment and Durable Graft-versus-host Disease Control with Haploidentical Peripheral Blood and a Short-term Conditioning Regimen for Primary Graft Failure. 2015 Intern. Med. pmid:26521905
Kawakami K et al. Effects of oral tacrolimus as a rapid induction therapy in ulcerative colitis. 2015 World J. Gastroenterol. pmid:25684955
Cuellar-Rodriguez J et al. Matched related and unrelated donor hematopoietic stem cell transplantation for DOCK8 deficiency. 2015 Biol. Blood Marrow Transplant. pmid:25636378
Gao L and Sun Y In vitro interactions of antifungal agents and tacrolimus against Aspergillus biofilms. 2015 Antimicrob. Agents Chemother. pmid:26303797
Zhu LQ et al. Posterior reversible encephalopathy syndrome and graft-versus-host disease after liver transplantation: a case report and review of the literature. 2015 Int J Clin Pharmacol Ther pmid:26227100