tacrolimus

Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.

Cross Reference

Introduction

To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with tacrolimus?

tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with tacrolimus

MeSH term MeSH ID Detail
Myelitis D009187 1 associated lipids
Erythroplasia D004919 1 associated lipids
Migraine with Aura D020325 1 associated lipids
Hutchinson's Melanotic Freckle D018327 2 associated lipids
Lacerations D022125 1 associated lipids
Trauma, Nervous System D020196 2 associated lipids
Central Nervous System Viral Diseases D020805 1 associated lipids
Neuroaspergillosis D020953 2 associated lipids
Hepatopulmonary Syndrome D020065 1 associated lipids
Arm Injuries D001134 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with tacrolimus

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with tacrolimus?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with tacrolimus?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with tacrolimus?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with tacrolimus?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with tacrolimus?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with tacrolimus

Download all related citations
Per page 10 20 50 100 | Total 15051
Authors Title Published Journal PubMed Link
Rivelli RF et al. Early withdrawal of calcineurin inhibitor from a sirolimus-based immunosuppression stabilizes fibrosis and the transforming growth factor-β signalling pathway in kidney transplant. 2015 Nephrology (Carlton) pmid:25404086
Nakagawa K et al. Immunosuppression with tacrolimus improved reproductive outcome of women with repeated implantation failure and elevated peripheral blood TH1/TH2 cell ratios. 2015 Am. J. Reprod. Immunol. pmid:25394810
Cury Martins J et al. Topical tacrolimus for atopic dermatitis. 2015 Cochrane Database Syst Rev pmid:26132597
Prinz V et al. MRI heralds secondary nigral lesion after brain ischemia in mice: a secondary time window for neuroprotection. 2015 J. Cereb. Blood Flow Metab. pmid:26126863
Cantaluppi V et al. Neutrophil Gelatinase Associated Lipocalin Is an Early and Accurate Biomarker of Graft Function and Tissue Regeneration in Kidney Transplantation from Extended Criteria Donors. 2015 PLoS ONE pmid:26125566
Gordon P and Gooptu B Tacrolimus in idiopathic inflammatory myopathy-associated interstitial lung disease: defining roles and responders. 2015 Rheumatology (Oxford) pmid:25342374
Milam EC et al. Treatment of Scarring Alopecia in Discoid Variant of Chronic Cutaneous Lupus Erythematosus With Tacrolimus Lotion, 0.3. 2015 JAMA Dermatol pmid:26039539
Shi WL et al. Effects of the CYP3A4*1B Genetic Polymorphism on the Pharmacokinetics of Tacrolimus in Adult Renal Transplant Recipients: A Meta-Analysis. 2015 PLoS ONE pmid:26039043
Wozniak LJ et al. Donor-specific HLA Antibodies Are Associated With Late Allograft Dysfunction After Pediatric Liver Transplantation. 2015 Transplantation pmid:26038872
Argudo A et al. Liver Transplant Patient Carriers of Polymorphism Cyp3a5*1 Donors May Need More Doses of Tacrolimus From the First Month After Transplantation. 2015 Transplant. Proc. pmid:26518936
de Jonge H et al. The CYP3A4*22 C>T single nucleotide polymorphism is associated with reduced midazolam and tacrolimus clearance in stable renal allograft recipients. 2015 Pharmacogenomics J. pmid:25287072
Jin S et al. Exposure to Radiocontrast Agents Induces Pancreatic Inflammation by Activation of Nuclear Factor-κB, Calcium Signaling, and Calcineurin. 2015 Gastroenterology pmid:25980752
Wiseman AC Induction Therapy in Renal Transplantation: Why? What Agent? What Dose? We May Never Know. 2015 Clin J Am Soc Nephrol pmid:25979977
Ratanatharathorn V et al. Low-dose antithymocyte globulin enhanced the efficacy of tacrolimus and mycophenolate for GVHD prophylaxis in recipients of unrelated SCT. 2015 Bone Marrow Transplant. pmid:25285804
Tanriover B et al. Induction Therapies in Live Donor Kidney Transplantation on Tacrolimus and Mycophenolate With or Without Steroid Maintenance. 2015 Clin J Am Soc Nephrol pmid:25979971
Kang YZ et al. Autoimmune hepatitis-primary biliary cirrhosis concurrent with biliary stricture after liver transplantation. 2015 World J. Gastroenterol. pmid:25717264
Hategan A and Bourgeois JA Tacrolimus neurotoxicity and the role of the Renin-Angiotensin system. 2015 J Neuropsychiatry Clin Neurosci pmid:25923858
Blasco-Morente G et al. Long-Standing Presternal Plaque. 2015 Actas Dermosifiliogr pmid:25917959
Ferraresso M et al. Relationship between mRNA expression levels of CYP3A4, CYP3A5 and SXR in peripheral mononuclear blood cells and aging in young kidney transplant recipients under tacrolimus treatment. 2015 Pharmacogenomics pmid:25916520
Wang M et al. Enteric polymer based on pH-responsive aliphatic polycarbonate functionalized with vitamin E to facilitate oral delivery of tacrolimus. 2015 Biomacromolecules pmid:25714622
Josephson MA et al. American society of Nephrology Quiz and Questionnaire 2014: transplantation. 2015 Clin J Am Soc Nephrol pmid:25862775
Peña C et al. [Secondary acute myeloid leukemia in a lung allograft recipient. Report of one case]. 2015 Rev Med Chil pmid:25860370
Watanabe K et al. The participation of insulin-like growth factor-binding protein 3 released by astrocytes in the pathology of Alzheimer's disease. 2015 Mol Brain pmid:26637371
Wang L et al. Effect of CYP3A5 gene polymorphisms on tacrolimus concentration/dosage ratio in adult liver transplant patients. 2015 Genet. Mol. Res. pmid:26634478
Solomon SR et al. Total Body Irradiation-Based Myeloablative Haploidentical Stem Cell Transplantation Is a Safe and Effective Alternative to Unrelated Donor Transplantation in Patients Without Matched Sibling Donors. 2015 Biol. Blood Marrow Transplant. pmid:25797174
Dedinská I et al. Waist circumference as an independent risk factor for NODAT. 2015 Ann. Transplant. pmid:25791039
Suzuki N et al. In vivo regulation of erythropoiesis by chemically inducible dimerization of the erythropoietin receptor intracellular domain. 2015 PLoS ONE pmid:25790231
Heneberg P et al. Pimecrolimus Is a Potent Inhibitor of Allergic Reactions to Hymenopteran Venom Extracts and Birch Pollen Allergen In Vitro. 2015 PLoS ONE pmid:26562153
Marcus EA et al. Successful term pregnancy in an intestine-pancreas transplant recipient with chronic graft dysfunction and parenteral nutrition dependence: a case report. 2015 Transplant. Proc. pmid:25724255
Dias PH et al. Effects of immunosuppression with tacrolimus and mycophenolate mofetil on renal histology and function in single kidney rats submitted to ischemia and reperfusion. 2015 Acta Cir Bras pmid:25714692
San Miguel C et al. Immunosuppression Strategies in the Treatment of Hepatocellular Carcinoma in Virgen de las Nieves University Hospital. 2015 Transplant. Proc. pmid:26518930
Kadlub N et al. The calcineurin inhibitor tacrolimus as a new therapy in severe cherubism. 2015 J. Bone Miner. Res. pmid:25491283
Katayama K et al. Inhibition of radiographic joint damage in rheumatoid arthritis patients in DAS28 remission using single- or combined with methotrexate non biological disease-modifying antirheumatic drug therapy in routine clinical practice. 2015 Mod Rheumatol pmid:24983407
Yessayan L et al. Race, Calcineurin Inhibitor Exposure, and Renal Function After Solid Organ Transplantation. 2015 Transplant. Proc. pmid:26707323
Wang Y et al. Justification of noninferiority margin: methodology considerations in an exposure-response analysis. 2015 Clin. Pharmacol. Ther. pmid:25670256
Dumortier T et al. Estimating the contribution of everolimus to immunosuppressive efficacy when combined with tacrolimus in liver transplantation: a model-based approach. 2015 Clin. Pharmacol. Ther. pmid:25669933
Dai DS et al. Protective Effect of Salvia Przewalskii Extract on Puromycin-Induced Podocyte Injury. 2015 Am. J. Nephrol. pmid:26439819
Xie X et al. mTOR inhibitor versus mycophenolic acid as the primary immunosuppression regime combined with calcineurin inhibitor for kidney transplant recipients: a meta-analysis. 2015 BMC Nephrol pmid:26126806
Kume K et al. Screening for a gene deletion mutant whose temperature sensitivity is suppressed by FK506 in budding yeast and its application for a positive screening for drugs inhibiting calcineurin. 2015 Biosci. Biotechnol. Biochem. pmid:25614218
Oguni H and Hayashi M [Topics for authorization of new intravenous antiepileptic drugs and tacrolimus for autoimmune epilepsy]. 2015 No To Hattatsu pmid:26349372
Dave CN et al. Innovative use of intravesical tacrolimus for hemorrhagic radiation cystitis. 2015 Int Urol Nephrol pmid:26347076
Wu J et al. MicroRNA-30 family members regulate calcium/calcineurin signaling in podocytes. 2015 J. Clin. Invest. pmid:26436650
Bhadauria D et al. Cryptosporidium infection after renal transplantation in an endemic area. 2015 Transpl Infect Dis pmid:25620388
Luger T et al. Pimecrolimus in atopic dermatitis: consensus on safety and the need to allow use in infants. 2015 Pediatr Allergy Immunol pmid:25557211
Burke MT et al. Genetics and nonmelanoma skin cancer in kidney transplant recipients. 2015 Pharmacogenomics pmid:25616102
Schnitzler F et al. Solid Organ Transplantation in Patients with Inflammatory Bowel Diseases (IBD): Analysis of Transplantation Outcome and IBD Activity in a Large Single Center Cohort. 2015 PLoS ONE pmid:26288187
Aruch DB and Renteria A Simultaneous PRES and TMA secondary to tacrolimus after allogeneic bone marrow transplant. 2015 Blood pmid:26287041
Chakraborty S et al. Prediction of in vivo drug performance using in vitro dissolution coupled with STELLA: a study with selected drug products. 2015 Drug Dev Ind Pharm pmid:25494535
Hauch A et al. Generics: are all immunosuppression agents created equally? 2015 Surgery pmid:26206317
Türkoğlu O et al. Are antimicrobial peptides related to cyclosporine A-induced gingival overgrowth? 2015 Arch. Oral Biol. pmid:25555253