tacrolimus

Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.

Cross Reference

Introduction

To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with tacrolimus?

tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with tacrolimus

MeSH term MeSH ID Detail
Myelitis D009187 1 associated lipids
Erythroplasia D004919 1 associated lipids
Migraine with Aura D020325 1 associated lipids
Hutchinson's Melanotic Freckle D018327 2 associated lipids
Lacerations D022125 1 associated lipids
Trauma, Nervous System D020196 2 associated lipids
Central Nervous System Viral Diseases D020805 1 associated lipids
Neuroaspergillosis D020953 2 associated lipids
Hepatopulmonary Syndrome D020065 1 associated lipids
Arm Injuries D001134 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with tacrolimus

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with tacrolimus?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with tacrolimus?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with tacrolimus?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with tacrolimus?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with tacrolimus?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with tacrolimus

Download all related citations
Per page 10 20 50 100 | Total 15051
Authors Title Published Journal PubMed Link
Aktürk S et al. Pregnancy After Kidney Transplantation: Outcomes, Tacrolimus Doses, and Trough Levels. 2015 Transplant. Proc. pmid:26093738
Rahman S et al. Nordihydroguiaretic acid attenuates skin tumorigenesis in Swiss albino mice with the condition of topical co-administration of an immunosuppressant. 2015 Chem. Biol. Interact. pmid:25770929
Rossetto AM et al. The full electron structure of the FKBP12/FK506 complex. 2015 J. Biomol. Struct. Dyn. pmid:24471694
Ma R et al. FK506 ameliorates podocyte injury in type 2 diabetic nephropathy by down-regulating TRPC6 and NFAT expression. 2015 Int J Clin Exp Pathol pmid:26823720
Kaieda S et al. Successful treatment of macrophage activation syndrome in a patient with dermatomyositis by combination with immunosuppressive therapy and plasmapheresis. 2015 Mod Rheumatol pmid:24252010
Kawaoka T et al. Two patients treated with simeprevir plus pegylated-interferon and ribavirin triple therapy for recurrent hepatitis C after living donor liver transplantation: case report. 2015 Transplant. Proc. pmid:25891736
Ichimaru N et al. Risk factors and incidence for lipid abnormalities in kidney transplant patients. 2015 Transplant. Proc. pmid:25891708
Bruckmueller H et al. Which Genetic Determinants Should be Considered for Tacrolimus Dose Optimization in Kidney Transplantation? A Combined Analysis of Genes Affecting the CYP3A Locus. 2015 Ther Drug Monit pmid:25271728
Moscovici BK et al. Treatment of Sjögren's syndrome dry eye using 0.03% tacrolimus eye drop: Prospective double-blind randomized study. 2015 Cont Lens Anterior Eye pmid:25956572
Kim D et al. Hydrogen sulfide and hypoxia-induced changes in TASK (K2P3/9) activity and intracellular Ca(2+) concentration in rat carotid body glomus cells. 2015 Respir Physiol Neurobiol pmid:25956223
Torres-Espín A et al. Immunosuppression of allogenic mesenchymal stem cells transplantation after spinal cord injury improves graft survival and beneficial outcomes. 2015 J. Neurotrauma pmid:25203134
Rojas L et al. Effect of CYP3A5*3 on kidney transplant recipients treated with tacrolimus: a systematic review and meta-analysis of observational studies. 2015 Pharmacogenomics J. pmid:25201288
Chung YW et al. Transcriptional activation of nuclear-related factor 2 by FK506 in Jurkat T cells. 2015 Transplant. Proc. pmid:25891728
Hur J et al. Systems pharmacological analysis of drugs inducing stevens-johnson syndrome and toxic epidermal necrolysis. 2015 Chem. Res. Toxicol. pmid:25811541
Malvezzi P and Rostaing L The safety of calcineurin inhibitors for kidney-transplant patients. 2015 Expert Opin Drug Saf pmid:26329325
Pidala J et al. Prolonged sirolimus administration after allogeneic hematopoietic cell transplantation is associated with decreased risk for moderate-severe chronic graft-versus-host disease. 2015 Haematologica pmid:25840599
Tsai MK et al. B cells and immunoglobulin in ABO-incompatible renal transplant patients receiving rituximab and double filtration plasmapheresis. 2015 J. Formos. Med. Assoc. pmid:25839769
Rajaganapathy BR et al. Intravesical Liposomal Tacrolimus Protects against Radiation Cystitis Induced by 3-Beam Targeted Bladder Radiation. 2015 J. Urol. pmid:25839382
Furlan SN et al. Transcriptome analysis of GVHD reveals aurora kinase A as a targetable pathway for disease prevention. 2015 Sci Transl Med pmid:26606970
Diaz-Siso JR et al. Initial experience of dual maintenance immunosuppression with steroid withdrawal in vascular composite tissue allotransplantation. 2015 Am. J. Transplant. pmid:25777324
Fujibayashi T et al. Comparison of efficacy and safety of tacrolimus and methotrexate in combination with abatacept in patients with rheumatoid arthritis; a retrospective observational study in the TBC Registry. 2015 Mod Rheumatol pmid:25775147
Lehman N et al. Left subconjunctival hemorrhage · renal dysfunction · international normalized ratio of 4.5 · Dx? 2015 J Fam Pract pmid:26551480
Boloori A et al. Characterization of Remitting and Relapsing Hyperglycemia in Post-Renal-Transplant Recipients. 2015 PLoS ONE pmid:26551468
Lightman S et al. Pegylated interferon-α-2b reduces corticosteroid requirement in patients with Behçet's disease with upregulation of circulating regulatory T cells and reduction of Th17. 2015 Ann. Rheum. Dis. pmid:25269831
Mahajan R et al. Co-localization of agminated congenital melanocytic nevi with vitiligo vulgaris: an unusual presentation. 2015 Int. J. Dermatol. pmid:25039486
TruneÄŒka P et al. Renal Function in De Novo Liver Transplant Recipients Receiving Different Prolonged-Release Tacrolimus Regimens-The DIAMOND Study. 2015 Am. J. Transplant. pmid:25707487
Adam R et al. Improved survival in liver transplant recipients receiving prolonged-release tacrolimus in the European Liver Transplant Registry. 2015 Am. J. Transplant. pmid:25703527
Yokoyama Y et al. Corticosteroid-sparing effect of tacrolimus in the initial treatment of dermatomyositis and polymyositis. 2015 Mod Rheumatol pmid:25775144
Asrani SK and O'Leary JG Can one pill a day keep rejection away? 2015 Am. J. Transplant. pmid:25703394
Chen QQ et al. Kaposi's Varicelliform Eruption During Long-term Treatment of Rosacea with 0.03% Tacrolimus Ointment. 2015 Chin. Med. J. pmid:26481759
Peksa GD et al. Dosing algorithm for concomitant administration of sirolimus, tacrolimus, and an azole after allogeneic hematopoietic stem cell transplantation. 2015 J Oncol Pharm Pract pmid:24938293
Shengyou Y et al. Influence of tacrolimus on podocyte injury inducted by angiotensin II. 2015 J Renin Angiotensin Aldosterone Syst pmid:25650384
Carenco C et al. Tacrolimus and the risk of solid cancers after liver transplant: a dose effect relationship. 2015 Am. J. Transplant. pmid:25648361
Mizokami D et al. Tacrolimus prevents laryngotracheal stenosis in an acute-injury rat model. 2015 Laryngoscope pmid:25647147
Coelho R et al. Nodular Regenerative Hyperplasia after Liver Transplantation Complicated with Inferior Vena Cava Stenosis: a Clue for Etiopathogenesis? 2015 J Gastrointestin Liver Dis pmid:26405712
Romanowski M et al. Interleukin-17 gene polymorphisms in patients with post-transplant diabetes mellitus. 2015 Eur Rev Med Pharmacol Sci pmid:26400516
Sato M et al. Multifocal Fibrosclerosis with Hypertrophic Pachymeningitis and a Soft Tissue Mass around the Thoracic Vertebral Bodies: A Case Report with Review of the Literature. 2015 Intern. Med. pmid:26328659
Chittock J et al. Comparing the Effect of a Twice-weekly Tacrolimus and Betamethasone Valerate Dose on the Subclinical Epidermal Barrier Defect in Atopic Dermatitis. 2015 Acta Derm. Venereol. pmid:25594610
Ge Y et al. The efficacy of tacrolimus in patients with refractory dermatomyositis/polymyositis: a systematic review. 2015 Clin. Rheumatol. pmid:26328518
Velioglu A et al. Association of BK Virus Titers With Lymphocyte Count in Renal Transplant Patients. 2015 Transplant. Proc. pmid:26093733
Demir T et al. Cancer Screening of Renal Transplant Patients Undergoing Long-Term Immunosuppressive Therapy. 2015 Transplant. Proc. pmid:26093731
Webb NJ et al. Corticosteroid-free Kidney Transplantation Improves Growth: 2-Year Follow-up of the TWIST Randomized Controlled Trial. 2015 Transplantation pmid:25539467
Schaap MM et al. A novel toxicogenomics-based approach to categorize (non-)genotoxic carcinogens. 2015 Arch. Toxicol. pmid:25270620
Yoo MC et al. Steroid-free Liver Transplantation Using Rabbit Antithymocyte Globulin Induction in 500 Consecutive Patients. 2015 Transplantation pmid:25539464
Seeling W et al. Knowledge-based immunosuppressive therapy for kidney transplant patients--from theoretical model to clinical integration. 2015 Stud Health Technol Inform pmid:26262418
Wardhana EA and Datau A patient with plaque type morphea mimicking systemic lupus erythematosus. 2015 Acta Med Indones pmid:26260557
Clift DE et al. Effects of embryonic cyclosporine exposures on brain development and behavior. 2015 Behav. Brain Res. pmid:25591474
Togashi M et al. Effect of CYP3A5 and ABCB1 polymorphisms on the interaction between tacrolimus and itraconazole in patients with connective tissue disease. 2015 Eur. J. Clin. Pharmacol. pmid:26184414
Inamoto Y et al. Tacrolimus versus Cyclosporine after Hematopoietic Cell Transplantation for Acquired Aplastic Anemia. 2015 Biol. Blood Marrow Transplant. pmid:26033280
Regelmann MO et al. New-onset diabetes mellitus after pediatric liver transplantation. 2015 Pediatr Transplant pmid:26032592