| MeSH term | MeSH ID | Detail |
|---|---|---|
| Psoriasis | D011565 | 47 associated lipids |
| Precancerous Conditions | D011230 | 48 associated lipids |
| Fatty Liver | D005234 | 48 associated lipids |
| Thrombosis | D013927 | 49 associated lipids |
| Osteosarcoma | D012516 | 50 associated lipids |
| Kidney Failure, Chronic | D007676 | 51 associated lipids |
| Leukemia, Myeloid | D007951 | 52 associated lipids |
| Parkinson Disease | D010300 | 53 associated lipids |
| Nerve Degeneration | D009410 | 53 associated lipids |
| Diabetes Mellitus, Type 1 | D003922 | 56 associated lipids |
tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (2)
- Am. J. Physiol. Renal Physiol. (1)
- Drug Metab. Dispos. (1)
- Others (1)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Schlegel A et al. | Hypothermic Oxygenated Perfusion (HOPE) downregulates the immune response in a rat model of liver transplantation. | 2014 | Ann. Surg. | pmid:25243553 |
| Fealy MJ et al. | Efficacy of rapamycin and FK 506 in prolonging rat hind limb allograft survival. | 1994 | Ann. Surg. | pmid:7507657 |
| Vivarelli M et al. | Liver transplantation for hepatocellular carcinoma under calcineurin inhibitors: reassessment of risk factors for tumor recurrence. | 2008 | Ann. Surg. | pmid:18948815 |
| Abu-Elmagd K et al. | Clinical intestinal transplantation: a decade of experience at a single center. | 2001 | Ann. Surg. | pmid:11524593 |
| Petruzzo P et al. | Outcomes after bilateral hand allotransplantation: a risk/benefit ratio analysis. | 2015 | Ann. Surg. | pmid:24646555 |
| Todo S et al. | Single-center experience with primary orthotopic liver transplantation with FK 506 immunosuppression. | 1994 | Ann. Surg. | pmid:7522431 |
| Lerut J et al. | Tacrolimus monotherapy in liver transplantation: one-year results of a prospective, randomized, double-blind, placebo-controlled study. | 2008 | Ann. Surg. | pmid:19092340 |
| Bartlett ST et al. | Equivalent success of simultaneous pancreas kidney and solitary pancreas transplantation. A prospective trial of tacrolimus immunosuppression with percutaneous biopsy. | 1996 | Ann. Surg. | pmid:8857849 |
| Todo S et al. | Intestinal transplantation in composite visceral grafts or alone. | 1992 | Ann. Surg. | pmid:1384443 |
| McCourtie AS et al. | Synergistic protection in lung ischemia-reperfusion injury with calcineurin and thrombin inhibition. | 2010 | Ann. Thorac. Surg. | pmid:20494024 |
| Laubach VE | Invited commentary. | 2010 | Ann. Thorac. Surg. | pmid:20494025 |
| Li S et al. | Intrathymic inoculation of donor bone marrow induces long-term acceptance of lung allografts. | 2003 | Ann. Thorac. Surg. | pmid:12537225 |
| Sugita M et al. | Pharmacologic modulation of alveolar liquid clearance in transplanted lungs by phentolamine and FK506. | 2009 | Ann. Thorac. Surg. | pmid:19699927 |
| Moffatt-Bruce S | Invited commentary. | 2009 | Ann. Thorac. Surg. | pmid:19699928 |
| Thyagarajan GK et al. | FK506-induced fulminant leukoencephalopathy after single-lung transplantation. | 1997 | Ann. Thorac. Surg. | pmid:9386723 |
| Leshnower BG et al. | Cyclosporine preserves mitochondrial morphology after myocardial ischemia/reperfusion independent of calcineurin inhibition. | 2008 | Ann. Thorac. Surg. | pmid:18805178 |
| Chambers DJ | Invited commentary. | 2008 | Ann. Thorac. Surg. | pmid:18805179 |
| Nathan M et al. | Cyclosporin A but not FK-506 protects against dopamine-induced apoptosis in the stunned heart. | 2005 | Ann. Thorac. Surg. | pmid:15854943 |
| Hirai T et al. | A short course of FK506 can induce limited donor-specific graft acceptance. | 1994 | Ann. Thorac. Surg. | pmid:7520685 |
| Armitage JM et al. | Clinical trial of FK 506 immunosuppression in adult cardiac transplantation. | 1992 | Ann. Thorac. Surg. | pmid:1379032 |
| Oto T et al. | Calcineurin inhibitor-related cholestasis complicating lung transplantation. | 2010 | Ann. Thorac. Surg. | pmid:20417810 |
| Groetzner J et al. | Cardiac transplantation in pediatric patients: fifteen-year experience of a single center. | 2005 | Ann. Thorac. Surg. | pmid:15620914 |
| Inutsuka K et al. | Reconstruction of trachea and carina with immediate or cryopreserved allografts in dogs. | 1996 | Ann. Thorac. Surg. | pmid:8893587 |
| Bolman RM | Advantage--FK 506: reduced chronic rejection for lung transplant recipients. | 1995 | Ann. Thorac. Surg. | pmid:7545888 |
| Keenan RJ et al. | Clinical trial of tacrolimus versus cyclosporine in lung transplantation. | 1995 | Ann. Thorac. Surg. | pmid:7545889 |
| Foroncewicz B et al. | A comparison between two tacrolimus-based immunosuppression regimens in renal transplant recipients: 7-year follow-up. | 2013 | Ann. Transplant. | pmid:23896824 |
| Bäckman L and Persson CA | An observational study evaluating tacrolimus dose, exposure, and medication adherence after conversion from twice- to once-daily tacrolimus in liver and kidney transplant recipients. | 2014 | Ann. Transplant. | pmid:24637379 |
| Steinebrunner N et al. | Pharmacodynamic monitoring of nuclear factor of activated T cell-regulated gene expression in liver allograft recipients on immunosuppressive therapy with calcineurin inhibitors in the course of time and correlation with acute rejection episodes--a prospective study. | 2014 | Ann. Transplant. | pmid:24457606 |
| Gijsen VM et al. | Tacrolimus-induced nephrotoxicity and genetic variability: a review. | 2012 Apr-Jun | Ann. Transplant. | pmid:22743729 |
| Baron PW et al. | Post-Transplant Diabetes Mellitus After Kidney Transplant in Hispanics and Caucasians Treated with Tacrolimus-Based Immunosuppression. | 2017 | Ann. Transplant. | pmid:28533501 |
| Roan JN et al. | Dose-normalization for exposure to mycophenolic acid and the early clinical outcome in patients taking tacrolimus after heart transplantation. | 2013 | Ann. Transplant. | pmid:23792500 |
| Tanaka T et al. | Evaluation of immune function under conversion from Prograf to Advagraf in living donor liver transplantation. | 2013 | Ann. Transplant. | pmid:23792533 |
| El-Agroudy AE et al. | Long-term graft outcome in patients with chronic allograft dysfunction after immunosuppression modifications. | 2008 | Ann. Transplant. | pmid:19034223 |
| Zegarska J et al. | Mycophenolic Acid Metabolites Acyl-Glucuronide and Glucoside Affect the Occurrence of Infectious Complications and Bone Marrow Dysfunction in Liver Transplant Recipients. | 2015 | Ann. Transplant. | pmid:26313036 |
| Figurski MJ et al. | Pharmacokinetic monitoring of mycophenolic acid in heart transplant patients: correlation the side-effects and rejections with pharmacokinetic parameters. | 2012 Jan-Mar | Ann. Transplant. | pmid:22466911 |
| Acott P and Babel N | BK virus replication following kidney transplant: does the choice of immunosuppressive regimen influence outcomes? | 2012 Jan-Mar | Ann. Transplant. | pmid:22466913 |
| Bułanowski M et al. | Influence of conversion from cyclosporine A to tacrolimus on insulin sensitivity assessed by euglicaemic hyperinsulinemic clamp technique in patients after kidney transplantation. | 2012 Jul-Sep | Ann. Transplant. | pmid:23018257 |
| Baran DA and Galin ID | "One size fits all": immunosuppression in cardiac transplantation. | 2003 | Ann. Transplant. | pmid:12848376 |
| Eguchi S et al. | Intentional conversion from tacrolimus to cyclosporine for HCV-positive patients on preemptive interferon therapy after living donor liver transplantation. | 2007 | Ann. Transplant. | pmid:18344932 |
| Zahn A et al. | Mycophenolate mofetil combination therapy improves survival after liver transplantation. A single-center retrospective analysis. | 2013 | Ann. Transplant. | pmid:24088725 |
| WÅ‚odarczyk Z et al. | Freedom from rejection and stable kidney function are excellent criteria for steroid withdrawal in tacrolimus-treated kidney transplant recipients. | 2002 | Ann. Transplant. | pmid:12465429 |
| Urbanowicz T et al. | Comparison of conventional tacrolimus versus prolong release formula as initial therapy in heart transplantation. | 2014 | Ann. Transplant. | pmid:24949728 |
| Fuchs U et al. | Incidence of malignant neoplasia after heart transplantation--a comparison between cyclosporine a and tacrolimus. | 2014 | Ann. Transplant. | pmid:24953848 |
| Bösmüller C et al. | Tacrolimus monotherapy following alemtuzumab induction in combined kidney-pancreas transplantation: results of a prospective randomized trial. | 2012 | Ann. Transplant. | pmid:23274323 |
| Olczak-Kowalczyk D et al. | The status of dental and jaw bones in children and adolescents after kidney and liver transplantation. | 2012 | Ann. Transplant. | pmid:23274327 |
| Zakliczyński M et al. | Clinical application of monitoring mycophenolic acid trough concentration in heart transplant recipients--single center's experience. | 2005 | Ann. Transplant. | pmid:16218032 |
| Ruangkanchanasetr P et al. | Beta Cell Function and Insulin Resistance After Conversion from Tacrolimus Twice-Daily to Extended-Release Tacrolimus Once-Daily in Stable Renal Transplant Recipients. | 2016 | Ann. Transplant. | pmid:27980321 |
| Duvoux C et al. | Sustained virological response to antiviral therapy in a randomized trial of cyclosporine versus tacrolimus in liver transplant patients with recurrent hepatitis C infection. | 2015 | Ann. Transplant. | pmid:25588713 |
| Mijal J et al. | Formation of synapses between dendritic cells and lymphocytes in skin lymph in an allogeneic reaction. | 2002 | Ann. Transplant. | pmid:12854345 |
| Albano L et al. | Dosing of Enteric-Coated Mycophenolate Sodium Under Routine Conditions: An Observational, Multicenter Study in Kidney Transplantation. | 2016 | Ann. Transplant. | pmid:27122116 |