tacrolimus

Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.

Cross Reference

Introduction

To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with tacrolimus?

tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with tacrolimus

MeSH term MeSH ID Detail
Pulmonary Disease, Chronic Obstructive D029424 16 associated lipids
Denys-Drash Syndrome D030321 1 associated lipids
Papillomavirus Infections D030361 4 associated lipids
Hyperuricemia D033461 4 associated lipids
Hypoalbuminemia D034141 1 associated lipids
Mastocytosis, Cutaneous D034701 1 associated lipids
Cholecystolithiasis D041761 2 associated lipids
Intestinal Volvulus D045822 1 associated lipids
Ileus D045823 3 associated lipids
Coproporphyria, Hereditary D046349 1 associated lipids
Per page 10 20 50 100 | Total 613

PubChem Associated disorders and diseases

What pathways are associated with tacrolimus

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with tacrolimus?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with tacrolimus?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with tacrolimus?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with tacrolimus?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with tacrolimus?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with tacrolimus

Download all related citations
Per page 10 20 50 100 | Total 15051
Authors Title Published Journal PubMed Link
David-Neto E et al. Longitudinal Pharmacokinetics of Everolimus When Combined With Low-level of Tacrolimus in Elderly Renal Transplant Recipients. 2017 Transplantation pmid:27798513
Alloway RR Mounting Clinical Evidence With Tacrolimus Generic Products. 2017 Transplantation pmid:28749820
Wei L et al. Therapeutic Effects of FK506 on IgA Nephropathy Rat. 2017 Kidney Blood Press. Res. pmid:29179182
Li X et al. Tacrolimus induces fibroblasts apoptosis and reduces epidural fibrosis by regulating miR-429 and its target of RhoE. 2017 Biochem. Biophys. Res. Commun. pmid:28669722
Weidinger S et al. A 5-year randomized trial on the safety and efficacy of pimecrolimus in atopic dermatitis: a critical appraisal. 2017 Br. J. Dermatol. pmid:28868633
Chen YS et al. Population pharmacokinetic analysis of tacrolimus in Chinese myasthenia gravis patients. 2017 Acta Pharmacol. Sin. pmid:28552913
Kim HS et al. The Protective Effect of Febuxostat on Chronic Tacrolimus-Induced Nephrotoxicity in Rats. 2017 Nephron pmid:27701176
Berntsen HF et al. The fungal neurotoxin penitrem A induces the production of reactive oxygen species in human neutrophils at submicromolar concentrations. 2017 Toxicology pmid:29037868
Vanhove T et al. Fexofenadine, a Putative In Vivo P-glycoprotein Probe, Fails to Predict Clearance of the Substrate Tacrolimus in Renal Recipients. 2017 Clin. Pharmacol. Ther. pmid:28437851
Huang TQ et al. Protection of FK506 against neuronal apoptosis and axonal injury following experimental diffuse axonal injury. 2017 Mol Med Rep pmid:28339015
Truffinet O et al. Tacrolimus Exerts Only a Transient Effectiveness in Refractory Pediatric Crohn Disease: A Case Series. 2017 J. Pediatr. Gastroenterol. Nutr. pmid:27429426
Spallanzani V et al. Red blood cell exchange as an approach for treating a case of severe tacrolimus overexposure. 2017 Transfus. Apher. Sci. pmid:28223040
Kasahara M et al. Living donor liver transplantation during the first 3 months of life. 2017 Liver Transpl. pmid:28220684
Kirpalani A et al. Idiosyncratic drug reactions and membranous glomerulopathy. 2017 BMJ Case Rep pmid:28137906
Kim JM et al. Differences in Peripheral Blood Lymphocytes between Brand-Name and Generic Tacrolimus Used in Stable Liver Transplant Recipients. 2017 Med Princ Pract pmid:28092916
Naniwa T et al. Efficacy of add-on tacrolimus on methotrexate to maintain clinical remission after rediscontinuation of a tumor necrosis factor inhibitor in rheumatoid arthritis patients who relapsed shortly after discontinuation of the same tumor necrosis factor inhibitor due to clinical remission. 2017 Mod Rheumatol pmid:27143107
Yang D et al. JC polyomavirus nephropathy, a rare cause of transplant dysfunction: Case report and review of literature. 2017 Transpl Infect Dis pmid:28036142
Van Laecke S et al. Effect of Magnesium Supplements on Insulin Secretion After Kidney Transplantation: A Randomized Controlled Trial. 2017 Ann. Transplant. pmid:28848225
Triñanes J et al. Deciphering Tacrolimus-Induced Toxicity in Pancreatic β Cells. 2017 Am. J. Transplant. pmid:28432716
Dardis G et al. Cx43 suppresses evx1 expression to regulate joint initiation in the regenerating fin. 2017 Dev. Dyn. pmid:28577298