Kobayashi N et al. |
Abdominal organ cluster transplantation in pigs and FK506. |
1992 |
Transpl. Int. |
pmid:14621861
|
Metcalfe S et al. |
FK506 and rapamycin: differential sensitivity of human, baboon, cynomolgus monkey, dog and pig lymphocytes. |
1992 |
Transpl. Int. |
pmid:14621863
|
|
Japanese study of kidney transplantation: 1. Results of early phase II study. |
1992 |
Transpl. Int. |
pmid:14621866
|
|
Japanese study of FK 506 on kidney transplantation: 2. Follow-up study of FK 506-treated patients. |
1992 |
Transpl. Int. |
pmid:14621874
|
Chen TS et al. |
Microbial transformation of immunosuppressive compounds. I. Desmethylation of FK506 and immunomycin (FR 900520) by Actinoplanes sp. ATCC 53771. |
1992 |
J. Antibiot. |
pmid:1372307
|
Walpoth B et al. |
Prevention of cardiac allograft rejection by FK506 and rapamycin: assessment by histology and nuclear magnetic resonance. |
1992 |
Transpl. Int. |
pmid:14621877
|
Morisaki M and Arai T |
Identity of immunosuppressant FR-900520 with ascomycin. |
1992 |
J. Antibiot. |
pmid:1372308
|
Doi R et al. |
Effects of FK506 on exocrine pancreas in rats. |
1992 |
Pancreas |
pmid:1372739
|
Kawano K et al. |
FK 506 ameliorates normothermic liver ischemia in rats by suppressing production of tumor necrosis factor. |
1992 |
Transpl. Int. |
pmid:14621904
|
Furukawa H et al. |
The effect of bile duct ligation and bile diversion on FK506 pharmacokinetics in dogs. |
1992 |
Transplantation |
pmid:1373531
|
Sakr M et al. |
Cytomegalovirus infection of the upper gastrointestinal tract following liver transplantation--incidence, location, and severity in cyclosporine- and FK506-treated patients. |
1992 |
Transplantation |
pmid:1373535
|
Hirano Y et al. |
Morphological and functional changes of islets of Langerhans in FK506-treated rats. |
1992 |
Transplantation |
pmid:1373536
|
Takahara S et al. |
The in vitro immunosuppressive effect of deoxymethylspergualin in man as compared with FK506 and cyclosporine. |
1992 |
Transplantation |
pmid:1373537
|
Johnson MC et al. |
QT prolongation and Torsades de Pointes after administration of FK506. |
1992 |
Transplantation |
pmid:1373538
|
Sigal NH and Dumont FJ |
Cyclosporin A, FK-506, and rapamycin: pharmacologic probes of lymphocyte signal transduction. |
1992 |
Annu. Rev. Immunol. |
pmid:1375473
|
Chen TS et al. |
Microbial transformation of immunosuppressive compounds. II. Specific desmethylation of 13-methoxy group of FK 506 and FR 900520 by an unidentified Actinomycete ATCC 53828 [corrected]. |
1992 |
J. Antibiot. |
pmid:1375593
|
Meingassner JG and Stütz A |
Immunosuppressive macrolides of the type FK 506: a novel class of topical agents for treatment of skin diseases? |
1992 |
J. Invest. Dermatol. |
pmid:1375617
|
Schneck FX et al. |
Pediatric renal transplantation under FK-506 immunosuppression. |
1992 |
J. Urol. |
pmid:1375663
|
Connelly PR and Thomson JA |
Heat capacity changes and hydrophobic interactions in the binding of FK506 and rapamycin to the FK506 binding protein. |
1992 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:1375751
|
Lancaster JR et al. |
EPR detection of heme and nonheme iron-containing protein nitrosylation by nitric oxide during rejection of rat heart allograft. |
1992 |
J. Biol. Chem. |
pmid:1375934
|
Hirai T et al. |
The immunosuppressive effect of FK 506 on canine lung transplantation. |
1992 |
J. Thorac. Cardiovasc. Surg. |
pmid:1375967
|
Tai PK et al. |
Association of a 59-kilodalton immunophilin with the glucocorticoid receptor complex. |
1992 |
Science |
pmid:1376003
|
O'Keefe SJ et al. |
FK-506- and CsA-sensitive activation of the interleukin-2 promoter by calcineurin. |
1992 |
Nature |
pmid:1377361
|
Clipstone NA and Crabtree GR |
Identification of calcineurin as a key signalling enzyme in T-lymphocyte activation. |
1992 |
Nature |
pmid:1377362
|
Hasegawa S et al. |
Combination use of suboptimal dose of FK 506 and cyclosporine in canine lung transplantation. |
1992 |
J. Thorac. Cardiovasc. Surg. |
pmid:1279319
|
Peattie DA et al. |
Expression and characterization of human FKBP52, an immunophilin that associates with the 90-kDa heat shock protein and is a component of steroid receptor complexes. |
1992 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:1279700
|
Lhoëst G et al. |
Isolation and mass spectrometric identification of two metabolites of FK 506 from rat liver microsomal incubation media. |
1992 |
Pharm Acta Helv |
pmid:1279730
|
Benigni A et al. |
The acute effect of FK506 and cyclosporine on endothelial cell function and renal vascular resistance. |
1992 |
Transplantation |
pmid:1279848
|
Mor E et al. |
Late-onset acute rejection in orthotopic liver transplantation--associated risk factors and outcome. |
1992 |
Transplantation |
pmid:1279849
|
Minoda M et al. |
Effects of gamma-interferon and FK506 on resting B cell proliferation of New Zealand black/white F1 mice. |
1992 |
Microbiol. Immunol. |
pmid:1282197
|
Min DI et al. |
Visual compatibility of tacrolimus with commonly used drugs during simulated Y-site injection. |
1992 |
Am J Hosp Pharm |
pmid:1282779
|
Mochizuki M |
[Immunotherapy in ocular diseases]. |
1992 |
Nippon Ganka Gakkai Zasshi |
pmid:1283052
|
Olejniczak ET et al. |
A 4D HCCH-TOCSY experiment for assigning the side chain 1H and 13C resonances of proteins. |
1992 |
J. Biomol. NMR |
pmid:1283353
|
Bauer S et al. |
The effect of the new immunosuppressive drug FK506 on the formation of secondary metabolites of cyclosporin A. |
1992 |
Int J Clin Pharmacol Ther Toxicol |
pmid:1283385
|
Renoir JM et al. |
[Effect of immunosuppressants FK506 and rapamycin on the function of progesterone receptor: protein "p59-HBI", intersection between immunology and endocrinology?]. |
1992 |
C. R. Acad. Sci. III, Sci. Vie |
pmid:1284044
|
Natazuka T |
FK506 reverses adriamycin resistance in a multidrug-resistant human leukemia cell line. |
1992 |
Kobe J Med Sci |
pmid:1284834
|
Fukuse T et al. |
Optimal dose of FK 506 in canine lung allotransplantation. |
1992 |
Transplant. Proc. |
pmid:1379757
|
Wada H et al. |
Combination use of suboptimal doses of FK 506 and cyclosporine in canine lung transplantation. |
1992 |
Transplant. Proc. |
pmid:1379758
|
Cai X et al. |
Low-dose of FK 506 and associated blood levels in allotransplantation of rat liver, heart, and skin. |
1992 |
Transplant. Proc. |
pmid:1379759
|
Taki J et al. |
DNA analysis of peripheral blood mononuclear cells for early detection of hepatic graft rejection. |
1992 |
Transplant. Proc. |
pmid:1379760
|
Sato Y et al. |
FK 506 suppresses class II antigen expression in regenerating livers following partial hepatectomy in the rat. |
1992 |
Transplant. Proc. |
pmid:1379761
|
Stütz A |
Immunosuppressive macrolides. |
1992 |
Transplant. Proc. |
pmid:1379762
|
Leiva MC and Lyttle CR |
Leukocyte chemotactic activity of FKBP and inhibition by FK506. |
1992 |
Biochem. Biophys. Res. Commun. |
pmid:1379802
|
Iwasaki K et al. |
Effect of repeated oral doses of a novel immunosuppressive macrolide lactone on hepatic mixed-function oxidase system in the rat. Comparative study with ciclosporin. |
1992 |
Arzneimittelforschung |
pmid:1379812
|
Pahl A and Keller U |
FK-506-binding proteins from streptomycetes producing immunosuppressive macrolactones of the FK-506 type. |
1992 |
J. Bacteriol. |
pmid:1381710
|
Takahashi N |
[Cyclophilin and FK506-binding protein]. |
1992 |
Seikagaku |
pmid:1381737
|
Lee TK et al. |
Mucosal glutamine utilization after small-bowel transplantation: an electrophysiologic study. |
1992 |
J. Surg. Res. |
pmid:1382152
|
Kaye RE et al. |
Effects of cyclosporin A and FK506 on Fc epsilon receptor type I-initiated increases in cytokine mRNA in mouse bone marrow-derived progenitor mast cells: resistance to FK506 is associated with a deficiency in FK506-binding protein FKBP12. |
1992 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:1382293
|
Edalji R et al. |
High-level expression of recombinant human FK-binding protein from a fusion precursor. |
1992 |
J. Protein Chem. |
pmid:1382438
|
Thomson AW and Starzl TE |
FK 506 and autoimmune disease: perspective and prospects. |
1992 |
Autoimmunity |
pmid:1382646
|
Christians U et al. |
Specific and sensitive measurement of FK506 and its metabolites in blood and urine of liver-graft recipients. |
1992 |
Clin. Chem. |
pmid:1382896
|
Chung J et al. |
Rapamycin-FKBP specifically blocks growth-dependent activation of and signaling by the 70 kd S6 protein kinases. |
1992 |
Cell |
pmid:1377606
|
Xu RX et al. |
Stereospecific assignments and chi 1 rotamers for FKBP when bound to ascomycin from 3JH alpha,H beta and 3HN,H beta coupling constants. |
1992 |
FEBS Lett. |
pmid:1377648
|
Petros AM et al. |
NMR studies of an FK-506 analog, [U-13C]ascomycin, bound to FK-506-binding protein. |
1992 |
J. Med. Chem. |
pmid:1377749
|
Strom TB |
Molecular immunology and immunopharmacology of allograft rejection. |
1992 |
Kidney Int. Suppl. |
pmid:1383599
|
Wang SC et al. |
FK-506 inhibits proliferation and IL-4 messenger RNA production by a T-helper 2 cell line. |
1992 |
J. Surg. Res. |
pmid:1383612
|
Mizuno K et al. |
Modulation of multidrug resistance by immunosuppressive agents: cyclosporin analogues, FK506 and mizoribine. |
1992 Jan-Feb |
Anticancer Res. |
pmid:1373592
|
Arai S et al. |
The impact of FK506 on graft coronary disease of rat cardiac allograft--a comparison with cyclosporine. |
1992 Jul-Aug |
J. Heart Lung Transplant. |
pmid:1379829
|
Fagiuoli S et al. |
FK 506: a new immunosuppressive agent for organ transplantation. Pharmacology, mechanism of action and clinical applications. |
1992 Jul-Aug |
Ital J Gastroenterol |
pmid:1381245
|
Tong J et al. |
Effect of FK-506 and cyclosporin A on in vitro CFU-GM growth in severe aplastic anemia patients. |
1992 Jul-Aug |
Haematologica |
pmid:1385279
|
Nazer H et al. |
FK 506 associated disorders in liver transplantation. |
1992 May-Jun |
J. Gastroenterol. Hepatol. |
pmid:1377038
|
Bowman H and Lennard TW |
Immunosuppressive drugs. |
1992 Nov 4-17 |
Br J Hosp Med |
pmid:1282440
|
Sattler M et al. |
Cytochrome P-450 3A enzymes are responsible for biotransformation of FK506 and rapamycin in man and rat. |
1992 Sep-Oct |
Drug Metab. Dispos. |
pmid:1385058
|
Nakajima K et al. |
Effects of triple therapy of cyclosporine, FK 506, and RS-61443 on allogeneic small bowel transplantation in dogs. |
1993 |
Transplant. Proc. |
pmid:7679821
|
Tzakis AG et al. |
Two-year experience with FK 506 in pediatric patients. |
1993 |
Transplant. Proc. |
pmid:7679822
|
Gibbs JF et al. |
Outcome analysis of FK 506 therapy for acute and chronic rejection. |
1993 |
Transplant. Proc. |
pmid:7679823
|
|
Morphological characteristics of renal allografts showing renal dysfunction under FK 506 therapy: is graft biopsy available to reveal the morphological findings corresponding with FK 506 nephropathy? Japanese FK 506 Study Group. |
1993 |
Transplant. Proc. |
pmid:7679824
|
Mañez R et al. |
Association between donor-recipient HLA-DR compatibility and cytomegalovirus hepatitis and chronic rejection in liver transplantation. |
1993 |
Transplant. Proc. |
pmid:7680170
|
McCauley J |
The nephrotoxicity of FK506 as compared with cyclosporine. |
1993 |
Curr. Opin. Nephrol. Hypertens. |
pmid:7532089
|
Woan MC et al. |
Characterization of the biopsy growth assay in monitoring cardiac transplant patients for rejection. |
1993 |
Transplant. Proc. |
pmid:7680171
|
Rilo HR et al. |
Effect of intraportal human islet transplantation on kidney graft survival in simultaneous kidney-islet allografts. |
1993 |
Transplant. Proc. |
pmid:7680172
|
Fukuzaki T et al. |
Induction of unresponsiveness to islet allograft by preoperative donor spleen cell injection and FK 506 treatment. |
1993 |
Transplant. Proc. |
pmid:7680173
|
Deardon DJ et al. |
Small bowel tonometry: a possible technique for detecting early small bowel allograft dysfunction. |
1993 |
Transplant. Proc. |
pmid:7505502
|
Demetris AJ et al. |
Hematolymphoid cell trafficking, microchimerism, and GVH reactions after liver, bone marrow, and heart transplantation. |
1993 |
Transplant. Proc. |
pmid:7505503
|
Pancer Z et al. |
cDNA cloning of a putative protochordate FK506-binding protein. |
1993 |
Biochem. Biophys. Res. Commun. |
pmid:7505578
|
Woodle ES et al. |
Recurrent rejection following FK 506 rescue therapy for acute hepatic allograft rejection. |
1993 |
Transplant. Proc. |
pmid:7682358
|
Woodle ES et al. |
FK 506 rescue therapy: early conversion improves efficacy. |
1993 |
Transplant. Proc. |
pmid:7682359
|
Woodle ES et al. |
FK 506 rescue therapy: the rapidity of rejection reversal is related to the subsequent development of CMV disease. |
1993 |
Transplant. Proc. |
pmid:7682360
|
Meiser BM et al. |
Simvastatin decreases accelerated graft vessel disease after heart transplantation in an animal model. |
1993 |
Transplant. Proc. |
pmid:7682363
|
McCauley J et al. |
Pilot trial of FK 506 in the management of steroid-resistant nephrotic syndrome. |
1993 |
Nephrol. Dial. Transplant. |
pmid:7508098
|
Schmitt J et al. |
Cloning and expression of a mouse cDNA encoding p59, an immunophilin that associates with the glucocorticoid receptor. |
1993 |
Gene |
pmid:7693550
|
Nishikawa T et al. |
Kinetic analysis of molecular interconversion of immunosuppressant FK506 by high-performance liquid chromatography. |
1993 |
Pharm. Res. |
pmid:7508108
|
Shafiee A et al. |
Enzymatic synthesis and immunosuppressive activity of novel desmethylated immunomycins (ascomycins). |
1993 |
J. Antibiot. |
pmid:7693638
|
Keicho N et al. |
Antilymphocytic activity of erythromycin distinct from that of FK506 or cyclosporin A. |
1993 |
J. Antibiot. |
pmid:7693639
|
Timerman AP et al. |
The calcium release channel of sarcoplasmic reticulum is modulated by FK-506-binding protein. Dissociation and reconstitution of FKBP-12 to the calcium release channel of skeletal muscle sarcoplasmic reticulum. |
1993 |
J. Biol. Chem. |
pmid:7693682
|
Takeda Y et al. |
Stimulation of endothelin mRNA and secretion in human endothelial cells by FK 506. |
1993 |
J. Cardiovasc. Pharmacol. |
pmid:7509973
|
Wallemacq PE et al. |
Improvement and assessment of enzyme-linked immunosorbent assay to detect low FK506 concentrations in plasma or whole blood within 6 hours. |
1993 |
Clin. Chem. |
pmid:7684956
|
Mochizuki M et al. |
A clinical trial of FK506 in refractory uveitis. |
1993 |
Am. J. Ophthalmol. |
pmid:7685147
|
Fenton M and Kay JE |
Thapsigargin activates lymphocytes via a different pathway from ionomycin. |
1993 |
Biochem. Soc. Trans. |
pmid:7510649
|
Renoir JM et al. |
Immunological identification of a 50 kDa Mr FK506-binding immunophilin as a component of the non-DNA binding, hsp90 and hsp70 containing, heterooligomeric form of the chick oviduct progesterone receptor. |
1993 |
C. R. Acad. Sci. III, Sci. Vie |
pmid:7522118
|
Nishizawa S et al. |
Therapeutic effect of a new immunosuppressant, FK-506, on vasospasm after subarachnoid hemorrhage. |
1993 |
Neurosurgery |
pmid:7687044
|
Warty V et al. |
FK506 measurement: comparison of different analytical methods. |
1993 |
Ther Drug Monit |
pmid:7687389
|
Iwata H et al. |
Suppression of allograft responses by combining donor alloantigen-specific intravenous presensitization with suboptimal doses of FK506. |
1993 |
Transplantation |
pmid:7687396
|
Roelen DL et al. |
Differential inhibition of primed alloreactive CTLs in vitro by clinically used concentrations of cyclosporine and FK506. |
1993 |
Transplantation |
pmid:7687397
|
Jost U et al. |
FK 506 treatment of intractable rejection after liver transplantation. |
1993 |
Transplant. Proc. |
pmid:7689276
|
Winkler M et al. |
Plasma level-guided low-dose FK 506 therapy in patients with early liver dysfunction after liver transplantation. |
1993 |
Transplant. Proc. |
pmid:7689277
|
Viebahn R et al. |
Simulation of hypoxic and preservation injury in human hepatocyte cultures: influence of FK 506 and cyclosporine. |
1993 |
Transplant. Proc. |
pmid:7689278
|
Dé P et al. |
Early steroid-resistant rejection following orthotopic liver transplantation: new aspects of treatment with FK 506 instead of OKT3? |
1993 |
Transplant. Proc. |
pmid:7689279
|
Lee KK et al. |
Successful treatment of ongoing intestinal allograft rejection permits recovery of graft structure and function. |
1993 |
Am. J. Surg. |
pmid:7678188
|
Galvin F et al. |
Effects of cyclosporin A, FK 506, and mycalamide A on the activation of murine CD4+ T cells by the murine B7 antigen. |
1993 |
Eur. J. Immunol. |
pmid:7678228
|