tacrolimus

Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.

Cross Reference

Introduction

To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with tacrolimus?

tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with tacrolimus

MeSH term MeSH ID Detail
Poxviridae Infections D011213 1 associated lipids
Seminoma D018239 2 associated lipids
Hepatic Insufficiency D048550 1 associated lipids
Myoclonic Cerebellar Dyssynergia D002527 1 associated lipids
Brachial Plexus Neuritis D020968 2 associated lipids
Lymphomatoid Granulomatosis D008230 2 associated lipids
Dysuria D053159 1 associated lipids
Mediastinal Diseases D008477 1 associated lipids
Hernia, Ventral D006555 1 associated lipids
Paraneoplastic Syndromes, Nervous System D020361 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with tacrolimus

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with tacrolimus?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with tacrolimus?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with tacrolimus?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with tacrolimus?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with tacrolimus?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with tacrolimus

Download all related citations
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Authors Title Published Journal PubMed Link
Kreuter A et al. 1% pimecrolimus, 0.005% calcipotriol, and 0.1% betamethasone in the treatment of intertriginous psoriasis: a double-blind, randomized controlled study. 2006 Arch Dermatol pmid:16983001
Stern RS Topical calcineurin inhibitors labeling: putting the "box" in perspective. 2006 Arch Dermatol pmid:16983018
Travis LB et al. Successful treatment of vitiligo with 0.1% tacrolimus ointment. 2003 Arch Dermatol pmid:12756092
Lepe V et al. A double-blind randomized trial of 0.1% tacrolimus vs 0.05% clobetasol for the treatment of childhood vitiligo. 2003 Arch Dermatol pmid:12756094
Plettenberg H et al. Childhood vitiligo and tacrolimus: immunomodulating treatment for an autoimmune disease. 2003 Arch Dermatol pmid:12756103
Lübbe J et al. Adults with atopic dermatitis and herpes simplex and topical therapy with tacrolimus: what kind of prevention? 2003 Arch Dermatol pmid:12756112
Bakos L and Bakos RM Focal acne during topical tacrolimus therapy for vitiligo. 2007 Arch Dermatol pmid:17875902
Laffitte E et al. Erosive pustular dermatosis of the scalp: treatment with topical tacrolimus. 2003 Arch Dermatol pmid:12810500
Chu J et al. Topical tacrolimus is a useful adjunctive therapy for bullous pemphigoid. 2003 Arch Dermatol pmid:12810523
Allen A et al. Significant absorption of topical tacrolimus in 3 patients with Netherton syndrome. 2001 Arch Dermatol pmid:11405764
Eichenfield LF et al. 1% pimecrolimus cream for atopic dermatitis. 2003 Arch Dermatol pmid:14568846
Thiers BH Topical tacrolimus: treatment failure in a patient with alopecia areata. 2000 Arch Dermatol pmid:10632221
Firooz A et al. Pimecrolimus cream, 1%, vs hydrocortisone acetate cream, 1%, in the treatment of facial seborrheic dermatitis: a randomized, investigator-blind, clinical trial. 2006 Arch Dermatol pmid:16924062
Bigby M A thorough systematic review of treatments for atopic eczema. 2001 Arch Dermatol pmid:11735714
Bernard LA et al. A rosacea-like granulomatous eruption in a patient using tacrolimus ointment for atopic dermatitis. 2003 Arch Dermatol pmid:12588240
Zonneveld IM et al. Topical tacrolimus is not effective in chronic plaque psoriasis. A pilot study. 1998 Arch Dermatol pmid:9762021
Van Leent EJ et al. Effectiveness of the ascomycin macrolactam SDZ ASM 981 in the topical treatment of atopic dermatitis. 1998 Arch Dermatol pmid:9681343
Lener EV et al. Successful treatment of erosive lichen planus with topical tacrolimus. 2001 Arch Dermatol pmid:11295919
Mehrabi D and Pandya AG A randomized, placebo-controlled, double-blind trial comparing narrowband UV-B Plus 0.1% tacrolimus ointment with narrowband UV-B plus placebo in the treatment of generalized vitiligo. 2006 Arch Dermatol pmid:16847214
Colebunders R et al. HIV eosinophilic folliculitis in Uganda. 2006 Arch Dermatol pmid:16847219
Neill SM and Lewis FM Vulvovaginal lichen planus: a disease in need of a unified approach. 2008 Arch Dermatol pmid:19015426
Cooper SM et al. Vulvovaginal lichen planus treatment: a survey of current practices. 2008 Arch Dermatol pmid:19015433
Le Cleach L et al. Is topical monotherapy effective for localized pyoderma gangrenosum? 2011 Arch Dermatol pmid:21242400
Pomerantz RG et al. Posttransplant cutaneous T-cell lymphoma: case reports and review of the association of calcineurin inhibitor use with posttransplant lymphoproliferative disease risk. 2010 Arch Dermatol pmid:20479299
Ehst BD and Warshaw EM Alcohol-induced application site erythema after topical immunomodulator use and its inhibition by aspirin. 2004 Arch Dermatol pmid:15313828
Sand C and Thomsen HK Topical tacrolimus ointment is an effective therapy for Hailey-Hailey disease. 2003 Arch Dermatol pmid:14623698
Sagransky MJ et al. A randomized controlled pilot study of the effects of an extra office visit on adherence and outcomes in atopic dermatitis. 2010 Arch Dermatol pmid:21173330
Laino L and DiCarlo A Palmoplantar pustular psoriasis: clinical and video thermographic evaluation before and after topical tacrolimus treatment. 2011 Arch Dermatol pmid:21690553
Eiling E et al. Pimecrolimus: a novel treatment for cetuximab-induced papulopustular eruption. 2008 Arch Dermatol pmid:18794482
Ng W and Ikeda S Mount Tsukuba and the origin of tacrolimus. 2009 Arch Dermatol pmid:19289758
Carroll CL et al. Topical tacrolimus ointment combined with 6% salicylic acid gel for plaque psoriasis treatment. 2005 Arch Dermatol pmid:15655140
Patel RR et al. The safety and efficacy of tacrolimus therapy in patients younger than 2 years with atopic dermatitis. 2003 Arch Dermatol pmid:12975161
Nagao K et al. A case of generalized pustular psoriasis treated with topical tacrolimus. 2003 Arch Dermatol pmid:12975175
Yan AC et al. The safety and efficacy of pimecrolimus, 1%, cream for the treatment of Netherton syndrome: results from an exploratory study. 2010 Arch Dermatol pmid:20083693
Ciurea AM et al. Complete and durable clinical response of malignant pyoderma to tacrolimus in combination with dapsone and prednisone. 2010 Arch Dermatol pmid:20083712
Castelo-Soccio L et al. Induced lentiginosis with use of topical calcineurin inhibitors. 2012 Arch Dermatol pmid:22710469
Mikhail M et al. Rapid enlargement of a malignant melanoma in a child with vitiligo vulgaris after application of topical tacrolimus. 2008 Arch Dermatol pmid:18427063
Olivier V et al. Treatment of chronic erosive oral lichen planus with low concentrations of topical tacrolimus: an open prospective study. 2002 Arch Dermatol pmid:12374539
Toutous-Trellu L et al. Topical tacrolimus for effective treatment of eosinophilic folliculitis associated with human immunodeficiency virus infection. 2005 Arch Dermatol pmid:16230556
Kunstfeld R et al. Successful treatment of vulvar lichen sclerosus with topical tacrolimus. 2003 Arch Dermatol pmid:12873877
Böhm M et al. Successful treatment of anogenital lichen sclerosus with topical tacrolimus. 2003 Arch Dermatol pmid:12873890
Shah KN and Yan AC Low but detectable serum levels of tacrolimus seen with the use of very dilute, extemporaneously compounded formulations of tacrolimus ointment in the treatment of patients with netherton syndrome. 2006 Arch Dermatol pmid:17043199
Antille C et al. Induction of rosaceiform dermatitis during treatment of facial inflammatory dermatoses with tacrolimus ointment. 2004 Arch Dermatol pmid:15096374
Banky JP et al. Successful treatment of epidermolysis bullosa pruriginosa with topical tacrolimus. 2004 Arch Dermatol pmid:15262686
Carroll PB et al. Effect of tacrolimus (FK506) in dystrophic epidermolysis bullosa: rationale and preliminary results. 1994 Arch Dermatol pmid:7526802
Rapaport MJ Topical tacrolimus. 2005 Arch Dermatol pmid:16301404
Cheng A and Mann C Oral erosive lichen planus treated with efalizumab. 2006 Arch Dermatol pmid:16785369
Mackelfresh J et al. Combination therapy of doxycycline and topical tacrolimus for venous ulcers. 2005 Arch Dermatol pmid:16301410
Sniezek PJ et al. Annular atrophic plaques on the arms of a 57-year-old woman. 2006 Arch Dermatol pmid:16785386
Hall VC et al. Ocular mucous membrane pemphigoid and ocular pemphigus vulgaris treated topically with tacrolimus ointment. 2003 Arch Dermatol pmid:12925404