| MeSH term | MeSH ID | Detail |
|---|---|---|
| Poxviridae Infections | D011213 | 1 associated lipids |
| Seminoma | D018239 | 2 associated lipids |
| Hepatic Insufficiency | D048550 | 1 associated lipids |
| Myoclonic Cerebellar Dyssynergia | D002527 | 1 associated lipids |
| Brachial Plexus Neuritis | D020968 | 2 associated lipids |
| Lymphomatoid Granulomatosis | D008230 | 2 associated lipids |
| Dysuria | D053159 | 1 associated lipids |
| Mediastinal Diseases | D008477 | 1 associated lipids |
| Hernia, Ventral | D006555 | 1 associated lipids |
| Paraneoplastic Syndromes, Nervous System | D020361 | 1 associated lipids |
tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (2)
- Am. J. Physiol. Renal Physiol. (1)
- Drug Metab. Dispos. (1)
- Others (1)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Lee YH and Song GG | Relative efficacy and safety of tacrolimus, mycophenolate mofetil, and cyclophosphamide as induction therapy for lupus nephritis: a Bayesian network meta-analysis of randomized controlled trials. | 2015 | Lupus | pmid:26162684 |
| Liao R et al. | Tacrolimus Protects Podocytes from Injury in Lupus Nephritis Partly by Stabilizing the Cytoskeleton and Inhibiting Podocyte Apoptosis. | 2015 | PLoS ONE | pmid:26161538 |
| Traitanon O et al. | Differential Effects of Tacrolimus versus Sirolimus on the Proliferation, Activation and Differentiation of Human B Cells. | 2015 | PLoS ONE | pmid:26087255 |
| Seo YG et al. | Solid self-nanoemulsifying drug delivery system (SNEDDS) for enhanced oral bioavailability of poorly water-soluble tacrolimus: physicochemical characterisation and pharmacokinetics. | 2015 | J Microencapsul | pmid:26079598 |
| Lee J et al. | A 12-month single arm pilot study to evaluate the efficacy and safety of sirolimus in combination with tacrolimus in kidney transplant recipients at high immunologic risk. | 2015 | J. Korean Med. Sci. | pmid:26028917 |
| Mabuchi M et al. | Improvement of solid material for affinity resins by application of long PEG spacers to capture the whole target complex of FK506. | 2015 | Bioorg. Med. Chem. Lett. | pmid:26025877 |
| Zhang D et al. | Multifunctional Poly(methyl vinyl ether-co-maleic anhydride)-graft-hydroxypropyl-β-cyclodextrin Amphiphilic Copolymer as an Oral High-Performance Delivery Carrier of Tacrolimus. | 2015 | Mol. Pharm. | pmid:26024817 |
| Huang G et al. | [Analysis on BK virus associated nephropathy related risk factors in renal transplant recipients]. | 2015 | Zhonghua Yi Xue Za Zhi | pmid:26814103 |
| Grammatikopoulos T et al. | Anti-CD20 Monoclonal Antibody Therapy in Functional Bile Salt Export Pump Deficiency After Liver Transplantation. | 2015 | J. Pediatr. Gastroenterol. Nutr. | pmid:24231640 |
| Leyking S et al. | Calcineurin inhibitors differentially alter the circadian rhythm of T-cell functionality in transplant recipients. | 2015 | J Transl Med | pmid:25885792 |
| Wang X et al. | Tacrolimus 0.03% ointment in labial discoid lupus erythematosus: A randomized, controlled clinical trial. | 2015 | J Clin Pharmacol | pmid:25951426 |
| Mistry NP et al. | Formulation and evaluation of tacrolimus-loaded galactosylated Poly(lactic-co-glycolic acid) nanoparticles for liver targeting. | 2015 | J. Pharm. Pharmacol. | pmid:25944126 |
| Ding L et al. | Clinical Immunosuppressants Inhibit Inflammatory, Proliferative, and Reprogramming Potential, But Not Angiogenesis of Human Pancreatic Duct Cells. | 2015 | Cell Transplant | pmid:25198311 |
| Zhou X et al. | Effect of immunosuppression on the human mesangial cell cycle. | 2015 | Mol Med Rep | pmid:25370945 |
| Peccerillo F et al. | Eosinophilic cellulitis. | 2015 | G Ital Dermatol Venereol | pmid:25946678 |
| Størset E et al. | Improved Tacrolimus Target Concentration Achievement Using Computerized Dosing in Renal Transplant Recipients--A Prospective, Randomized Study. | 2015 | Transplantation | pmid:25886918 |
| Montero N and Pascual J | Immunosuppression and Post-transplant Hyperglycemia. | 2015 | Curr Diabetes Rev | pmid:25824238 |
| Seo YG et al. | Preparation and pharmaceutical evaluation of new tacrolimus-loaded solid self-emulsifying drug delivery system. | 2015 | Arch. Pharm. Res. | pmid:25134927 |
| Eichenfield DZ and Eichenfield LF | Pimecrolimus is safe and effective in treating atopic dermatitis. | 2015 | J. Pediatr. | pmid:26603713 |
| Calabrese B and Halpain S | Differential targeting of dynamin-1 and dynamin-3 to nerve terminals during chronic suppression of neuronal activity. | 2015 | Mol. Cell. Neurosci. | pmid:25827095 |
| Li Z et al. | Tacrolimus Induces Insulin Resistance and Increases the Glucose Absorption in the Jejunum: A Potential Mechanism of the Diabetogenic Effects. | 2015 | PLoS ONE | pmid:26599323 |
| Madariaga ML et al. | Kidney-induced cardiac allograft tolerance in miniature swine is dependent on MHC-matching of donor cardiac and renal parenchyma. | 2015 | Am. J. Transplant. | pmid:25824550 |
| Chhatrala R et al. | Evolution of serum atherogenic risk in liver transplant recipients: Role of lipoproteins and metabolic and inflammatory markers. | 2015 | Liver Transpl. | pmid:25762084 |
| Soylu H et al. | Survival of renal transplant patients: data from a tertiary care center in Turkey. | 2015 | Transplant. Proc. | pmid:25769571 |
| Helmschrott M et al. | Advantageous effects of immunosuppression with tacrolimus in comparison with cyclosporine A regarding renal function in patients after heart transplantation. | 2015 | Drug Des Devel Ther | pmid:25759566 |
| Ohe M and Bohgaki T | A Case of Adult-Onset Still's Disease Treated with Monitoring of Serum Tacrolimus Levels. | 2015 | Bull Hosp Jt Dis (2013) | pmid:26535602 |
| Xiao A et al. | H2S, a novel gasotransmitter, involves in gastric accommodation. | 2015 | Sci Rep | pmid:26531221 |
| Abdel-Azim H et al. | Unrelated donor hematopoietic stem cell transplantation for the treatment of non-malignant genetic diseases: An alemtuzumab based regimen is associated with cure of clinical disease; earlier clearance of alemtuzumab may be associated with graft rejection. | 2015 | Am. J. Hematol. | pmid:26242764 |
| Liu X et al. | Associations of HSD11B1 polymorphisms with tacrolimus concentrations in Chinese renal transplant recipients with prednisone combined therapy. | 2015 | Drug Metab. Dispos. | pmid:25587129 |
| Pensi D et al. | An UPLC-MS/MS method coupled with automated on-line SPE for quantification of tacrolimus in peripheral blood mononuclear cells. | 2015 | J Pharm Biomed Anal | pmid:25698619 |
| Roche NA et al. | Long-Term Multifunctional Outcome and Risks of Face Vascularized Composite Allotransplantation. | 2015 | J Craniofac Surg | pmid:26468783 |
| BlažiÄ M et al. | Roles of the crotonyl-CoA carboxylase/reductase homologues in acetate assimilation and biosynthesis of immunosuppressant FK506 in Streptomyces tsukubaensis. | 2015 | Microb. Cell Fact. | pmid:26466669 |
| Wang JY and Fan H | P70S6 kinase phosphorylation: a new site to assess pharmacodynamy of sirolimus. | 2015 | Chin. Med. J. | pmid:25698201 |
| Van Driest SL and Webber SA | Pharmacogenomics: personalizing pediatric heart transplantation. | 2015 | Circulation | pmid:25645611 |
| Ishida K et al. | Evaluation of the Safety and Effectiveness of Add-On Tacrolimus in Patients with Rheumatoid Arthritis Who Failed to Show an Adequate Response to Biological DMARDs: The Interim Results of a Specific Drug Use-Results Survey of Tacrolimus. | 2015 | Drugs R D | pmid:26386566 |
| Chow SP et al. | Long-Term Outcomes of High-Risk Keratoplasty in Patients Receiving Systemic Immunosuppression. | 2015 | Cornea | pmid:26382894 |
| Lin NC et al. | Minimization or withdrawal of immunosuppressants in pediatric liver transplant recipients. | 2015 | J. Pediatr. Surg. | pmid:26377868 |
| Ogul H et al. | Severe toxic leukoencephalopathy associated with tacrolimus after living donor liver transplantation. | 2015 | Acta Neurol Belg | pmid:24854146 |
| Tsujiwaki M et al. | Warty intralymphatic histiocytosis successfully treated with topical tacrolimus. | 2015 | J Eur Acad Dermatol Venereol | pmid:24851952 |
| Elbadri A et al. | Factors affecting eGFR 5-year post-deceased donor renal transplant: analysis and predictive model. | 2015 | Ren Fail | pmid:25585951 |
| Krystel-Whittemore M et al. | Polyomavirus nephropathy of the native kidney in a patient with rheumatoid arthritis and pulmonary fibrosis. | 2015 | BMJ Case Rep | pmid:26318171 |
| Saint-Marcoux F et al. | How to handle missed or delayed doses of tacrolimus in renal transplant recipients? A pharmacokinetic investigation. | 2015 | Pharmacol. Res. | pmid:26316426 |
| Karam S and Wali RK | Current State of Immunosuppression: Past, Present, and Future. | 2015 | Crit. Rev. Eukaryot. Gene Expr. | pmid:26080606 |
| Aikawa Y et al. | Essential role of PU.1 in maintenance of mixed lineage leukemia-associated leukemic stem cells. | 2015 | Cancer Sci. | pmid:25529853 |
| Ãœnal CM and Steinert M | FKBPs in bacterial infections. | 2015 | Biochim. Biophys. Acta | pmid:25529296 |
| Higa M et al. | Spatial control of calcineurin in response to heat shock in fission yeast. | 2015 | Genes Cells | pmid:25529221 |
| Joshi S et al. | Phosphatase inhibition prevents the activity-dependent trafficking of GABAA receptors during status epilepticus in the young animal. | 2015 | Epilepsia | pmid:26248944 |
| Vaeth M et al. | Selective NFAT targeting in T cells ameliorates GvHD while maintaining antitumor activity. | 2015 | Proc. Natl. Acad. Sci. U.S.A. | pmid:25583478 |
| Wu B et al. | Triple immunosuppressive therapy in steroid-resistant nephrotic syndrome children with tacrolimus resistance or tacrolimus sensitivity but frequently relapsing. | 2015 | Nephrology (Carlton) | pmid:25312783 |
| Vives R et al. | Safety and Activity of UR-1505 in Atopic Dermatitis: A Randomized, Double-blind Phase II Exploratory Trial. | 2015 | Clin Ther | pmid:26163200 |