| MeSH term | MeSH ID | Detail |
|---|---|---|
| Diabetes Mellitus, Type 1 | D003922 | 56 associated lipids |
| Dermatitis, Contact | D003877 | 59 associated lipids |
| Pain | D010146 | 64 associated lipids |
| Reperfusion Injury | D015427 | 65 associated lipids |
| Cystic Fibrosis | D003550 | 65 associated lipids |
| Liver Cirrhosis | D008103 | 67 associated lipids |
| Melanoma | D008545 | 69 associated lipids |
| Colitis | D003092 | 69 associated lipids |
| Hyperlipidemias | D006949 | 73 associated lipids |
| Leukemia | D007938 | 74 associated lipids |
tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (2)
- Am. J. Physiol. Renal Physiol. (1)
- Drug Metab. Dispos. (1)
- Others (1)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Butcher SP et al. | Neuroprotective actions of FK506 in experimental stroke: in vivo evidence against an antiexcitotoxic mechanism. | 1997 | J. Neurosci. | pmid:9278529 |
| Hebebrand D et al. | Nerve xenograft transplantation. Immunosuppression with FK-506 and RS-61443. | 1997 | J Hand Surg Br | pmid:9222906 |
| Kageyama M et al. | FK506-binding proteins regulate smooth muscle contractility by altering neurotransmitter release. | 1997 | Eur. J. Pharmacol. | pmid:9314039 |
| de Paulis A et al. | Human synovial mast cells. II. Heterogeneity of the pharmacologic effects of antiinflammatory and immunosuppressive drugs. | 1997 | Arthritis Rheum. | pmid:9082935 |
| Göthel SF et al. | An internal FK506-binding domain is the catalytic core of the prolyl isomerase activity associated with the Bacillus subtilis trigger factor. | 1997 | Eur. J. Biochem. | pmid:9063446 |
| Dumont FJ | FK506 enhances IL-13 production by T cells activated through CD3/CD28. | 1997 | Int. Arch. Allergy Immunol. | pmid:9363914 |
| Paterson DL et al. | Could a herpesvirus mimic tacrolimus-induced leukoencephalopathy? | 1997 | Ann. Neurol. | pmid:9266742 |
| Ahsan N et al. | Successful reversal of acute vascular rejection in a renal allograft with combined mycophenolate mofetil and tacrolimus as primary immunotherapy. | 1997 | Clin Transplant | pmid:9113443 |
| Yoshimoto T et al. | [Leukoencephalopathy probably caused by tacrolimus hydrate after stem cell transplantation in a girl with MDS 7 monosomy]. | 1997 | Rinsho Ketsueki | pmid:9267167 |
| Singh N et al. | Invasive fungal infections in liver transplant recipients receiving tacrolimus as the primary immunosuppressive agent. | 1997 | Clin. Infect. Dis. | pmid:9114144 |
| Ito E and Tanaka Y | Influences of immunosuppressive agents, FK506 and cyclosporin on systemic Candida albicans infection in mice. | 1997 | Mycopathologia | pmid:9433807 |
| Boucek MM et al. | The Registry of the International Society of Heart and Lung Transplantation: first official pediatric report--1997. | 1997 | J. Heart Lung Transplant. | pmid:9436131 |
| Homey B et al. | A local lymph node assay to analyse immunosuppressive effects of topically applied drugs. | 1997 | Eur. J. Pharmacol. | pmid:9163567 |
| Ballantyne CM et al. | Pathophysiology and treatment of lipid perturbation after cardiac transplantation. | 1997 | Curr. Opin. Cardiol. | pmid:9192484 |
| Vella JP and Sayegh MH | Maintenance pharmacological immunosuppressive strategies in renal transplantation. | 1997 | Postgrad Med J | pmid:9338020 |
| Gruessner AC and Sutherland DE | Pancreas transplants for United States (US) and non-US cases as reported to the International Pancreas Transplant Registry (IPTR) and to the United Network for Organ Sharing (UNOS). | 1997 | Clin Transpl | pmid:9919390 |
| Odorico JS et al. | Advances in pancreas transplantation: the University of Wisconsin experience. | 1997 | Clin Transpl | pmid:9919400 |
| Pirenne J et al. | Donor-specific unmodified bone marrow transfusion does not facilitate intestinal engraftment after bowel transplantation in a porcine model. | 1997 | Surgery | pmid:9001555 |
| Felldin M et al. | Rescue therapy with tacrolimus (FK 506) in renal transplant recipients--a Scandinavian multicenter analysis. | 1997 | Transpl. Int. | pmid:9002146 |
| Guérette B et al. | Prevention by anti-LFA-1 of acute myoblast death following transplantation. | 1997 | J. Immunol. | pmid:9278346 |
| Gaber LW et al. | Renal histology with varying FK506 blood levels. | 1997 Feb-Mar | Transplant. Proc. | pmid:9122955 |
| Miller J et al. | FK 506 in kidney transplantation: results of the U.S.A. randomized comparative phase III study. The FK 506 Kidney Transplant Study Group. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123008 |
| Jordan ML et al. | Five-year experience with tacrolimus rescue for renal allograft rejection. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123009 |
| Cronin DC et al. | Tacrolimus therapy for refractory renal allograft rejection: experience with steroid withdrawal. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123010 |
| Zhu Y et al. | Prolongation of canine renal allograft survival by combining tacrolimus with antimetabolic agents. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123011 |
| Naraghi RM et al. | Long-term follow-up of tacrolimus rescue therapy for renal allograft rejection. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123013 |
| Lyne JC et al. | Cadaveric renal transplantation against a positive historic crossmatch under tacrolimus immunosuppression: long-term follow-up. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123015 |
| Zucker K et al. | Augmentation of mycophenolate mofetil pharmacokinetics in renal transplant patients receiving Prograf and CellCept in combination therapy. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123027 |
| Sellers M et al. | Incidence of late acute rejection and progression to chronic rejection in pediatric liver recipients. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123065 |
| Bonatti H et al. | Liver transplantation for acute liver failure in children under 1 year of age. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123068 |
| Shapiro R | Tacrolimus (FK-506) in kidney transplantation. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123077 |
| Cho JH et al. | Chronic rejection in pediatric liver transplantation. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123078 |
| Marino IR et al. | Preoperative assessment of risk in liver transplantation: a multivariate analysis in 2376 cases of the UW era. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123079 |
| Rayes N et al. | Distribution of lymphocyte subtypes in liver transplant recipients. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123103 |
| Platz KP et al. | Impact of immunosuppression and acute rejection on hepatitis B recurrence. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123107 |
| Ko S et al. | Predominant role of local immunosuppressive effect in enhanced efficacy of liposomal FK506 in organ transplantation. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123117 |
| Khanna A et al. | Cardiac changes at autopsy in adult liver transplant recipients under tacrolimus. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123118 |
| Busuttil RW and Holt CD | Tacrolimus (FK506) is superior to cyclosporine in liver transplantation. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123119 |
| Gavlik A et al. | Mycophenolate mofetil rescue therapy in liver transplant recipients. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123124 |
| Katoh H et al. | Effectiveness of 15-deoxyspergualin on steroid-resistant acute rejection in living related liver transplantation. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123125 |
| Meiser BM et al. | Tacrolimus (FK506) proves superior to OKT3 for treating episodes of persistent rejection following intrathoracic transplantation. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123150 |
| Misao T et al. | Effect of donor splenocyte transfusion with a simultaneous single injection of tacrolimus on lung allografts. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123153 |
| Morozumi K et al. | Electron-microscopic peritubular capillary lesion is a specific and useful diagnostic indicator for chronic rejection of renal allografts showing less specific morphologic lesions in the cyclosporine era. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123167 |
| Zipperle S et al. | Impaired T-cell IL-10 secretion and CD4 helper function in liver transplant patients treated with tacrolimus. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123208 |
| Li W et al. | High-dose cellular IL-10 exacerbates rejection and reverses effects of cyclosporine and tacrolimus in Mouse cardiac transplantation. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123209 |
| Nakajima H and Oka T | Analysis of biochemical and biological functions of Fas-ligand (FasL) and Fas on activated T cells in allo-immune response. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123217 |
| Gassel HJ et al. | Selective immunosuppression induces tolerance after liver transplantation: an immunohistochemical and cytofluorographic analysis of the graft and recipient immune system. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123253 |
| Burke GW et al. | Donor bone marrow infusion in simultaneous pancreas/kidney transplantation with OKT3 induction: evidence for augmentation of chimerism. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123275 |
| Ota H et al. | Intrathymic microchimerism predicts rejection response in allograft recipients. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123279 |
| Tashiro H et al. | Correlation of high-level microchimerism with graft acceptance in rat liver transplantation. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123287 |
| Wijnen RM et al. | Thymus atrophy in the nonhuman primate by FK506: an immunohistochemical study. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123292 |
| Kumano K et al. | Role of the transforming growth factor and monocyte chemoattractant protein in FK506-induced nephropathy in the rat. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123293 |
| Grochowicz PM et al. | Synergistic interaction between castanospermine and tacrolimus in a rat heart allograft model. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123296 |
| Guo Z et al. | Leflunomide, a potential immunosuppressant for pancreatic islet transplantation. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123314 |
| Walgenbach KJ et al. | Immunocytes of composite tissue allografts express elevated levels of TGF beta mRNA and protein during chronic rejection. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123418 |
| Millis JM et al. | Tacrolimus treatment of steroid-resistant rejection provides economic advantages compared with OKT3 therapy. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123421 |
| Corry RJ et al. | Pancreas transplantation with enteric drainage under tacrolimus induction therapy. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123457 |
| el-Ghoroury M et al. | Efficacy and safety of tacrolimus versus cyclosporine in kidney and pancreas transplant recipients. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123461 |
| Hariharan S et al. | Long-term renal and pancreas function with tacrolimus rescue therapy following kidney/pancreas transplantation. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123462 |
| Stratta RJ | Simultaneous use of tacrolimus and mycophenolate mofetil in combined pancreas-kidney transplant recipients: a multi-center report. The FK/MMF Multi-Center Study Group. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123463 |
| Gruessner AC et al. | Solitary pancreas transplants: improving results and factors that influence outcome. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123468 |
| Basadonna GP et al. | Pancreas after kidney transplantation: HLA mismatch does not preclude success. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123470 |
| Alessiani M et al. | Morphological and functional changes in small-bowel allografts of pigs under combined tacrolimus and mycophenolate mofetil immunosuppression. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123483 |
| Galvao FH et al. | Experimental animal model of graft-versus-host disease (GVHD) after small-bowel transplantation: characteristics of the model and application to developing treatment strategies. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123488 |
| Iacona I et al. | Mycophenolic acid in combination with FK 506: a pharmacokinetic study in piglets after small-bowel transplantation. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123489 |
| Batten P et al. | Effect of cyclosporine A and FK 506 on human T cell responses to xenogeneic and allogeneic endothelium: relative resistance of T cell/porcine endothelial interactions. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123582 |
| Troppmann C et al. | FK 506 versus cyclosporine A for steroid-free synergistic combination therapy with rapamycin in a discordant large animal donor xenoislet transplant model. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123585 |
| Matsumiya G et al. | Serum interleukin-6 level after cardiac xenotransplantation in primates. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123586 |
| Ohdan H et al. | Prolongation of hamster-to-rat liver xenograft survival by donor bone marrow augmentation. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123589 |
| Yamagami S et al. | Rejection mechanism and immunosuppression by FK 506 and anti-leukocyte function associated antigen-1 antibody in concordant corneal xenotransplantation. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123598 |
| Markus PM et al. | Allogeneic hepatocyte transplantation using FK 506. | 1997 Jan-Feb | Cell Transplant | pmid:9040958 |
| Lo Russo A et al. | Cyclosporin A potentiates receptor-activated [Ca2+]c increase. | 1997 Jan-May | J. Recept. Signal Transduct. Res. | pmid:9029487 |
| Billaud EM et al. | [Immunosuppression: a case of mucoviscidosis]. | 1997 Jul-Aug | Therapie | pmid:9437888 |
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| Tsubo T et al. | Elimination of FK-506 by continuous hemodiafiltration in a liver transplant patient. | 1997 Jul-Aug | ASAIO J. | pmid:9242954 |
| Frezza EE et al. | Non-lymphoid cancer after liver transplantation. | 1997 Jul-Aug | Hepatogastroenterology | pmid:9261620 |
| Firdaous I et al. | Excretion of tacrolimus glucuronides in human bile. | 1997 Jul-Sep | Eur J Drug Metab Pharmacokinet | pmid:9358202 |
| Guérette B et al. | Control of inflammatory damage by anti-LFA-1: increase success of myoblast transplantation. | 1997 Mar-Apr | Cell Transplant | pmid:9142441 |
| Min DI et al. | Time-dependent disposition of tacrolimus and its effect on endothelin-1 in liver allograft recipients. | 1997 May-Jun | Pharmacotherapy | pmid:9165550 |
| Healey MC et al. | Bovine fallopian tube epithelial cells, adult C57BL/6 mice, and non-neonatal pigs as models for cryptosporidiosis. | 1997 Nov-Dec | J. Eukaryot. Microbiol. | pmid:9508447 |
| Ikeda E et al. | Tacrolimus-rapamycin combination therapy for experimental autoimmune uveoretinitis. | 1997 Nov-Dec | Jpn. J. Ophthalmol. | pmid:9509307 |
| DiMartini AF et al. | Neuropsychiatric side effects of FK506 vs. cyclosporine A. First-week postoperative findings. | 1997 Nov-Dec | Psychosomatics | pmid:9427854 |
| Carreau A et al. | Comparative effects of FK-506, rapamycin and cyclosporin A, on the in vitro differentiation of dorsal root ganglia explants and septal cholinergic neurons. | 1997 Nov-Dec | Neuropharmacology | pmid:9517448 |
| Cox TH et al. | Bradycardia associated with intravenous administration of tacrolimus in a liver transplant recipient. | 1997 Nov-Dec | Pharmacotherapy | pmid:9399620 |
| Garattini S | Are me-too drugs justified? | 1997 Nov-Dec | J. Nephrol. | pmid:9442441 |
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| Hara K et al. | Implantation of xenogeneic transgenic neural plate tissues into parkinsonian rat brain. | 1997 Sep-Oct | Cell Transplant | pmid:9331504 |
| Van Buren D et al. | Renal function in primary liver transplant recipients receiving neoral (cyclosporine) versus prograf (tacrolimus). | 1998 | Transplant. Proc. | pmid:9636566 |
| Gayowski T et al. | Orthotopic liver transplantation in high-risk patients: risk factors associated with mortality and infectious morbidity. | 1998 | Transplantation | pmid:9500623 |
| Bruce DS et al. | Tacrolimus/mycophenolate provides superior immunosuppression relative to neoral/mycophenolate in synchronous pancreas-kidney transplantation. | 1998 | Transplant. Proc. | pmid:9636625 |
| Cicalese L et al. | Phenotypic and functional characteristics of intestinal intraepithelial lymphocytes during acute rejection of small intestinal allografts. | 1998 | Transpl. Int. | pmid:9561676 |
| Yoshimura N et al. | Effect of local immunosuppressive therapy with FK 506 on renal allograft survival in the mongrel dog. | 1998 | Transplant. Proc. | pmid:9838372 |
| Clemann N and Bechter R | Effects of rapamycin and FK 506 on rat Sertoli cells in vitro. | 1998 | Adv. Exp. Med. Biol. | pmid:10026935 |
| Koyama T et al. | [Effects of various drugs on IL-8 production by eosinophils collected from patients with allergic inflammation]. | 1998 | Jpn J Antibiot | pmid:9597507 |
| Tomono M et al. | Inhibitors of calcineurin block expression of cyclins A and E induced by fibroblast growth factor in Swiss 3T3 fibroblasts. | 1998 | Arch. Biochem. Biophys. | pmid:9606972 |
| Tarumi K et al. | The plasma FK506-binding protein 12 level is related to acute cellular rejection in small bowel transplantation. | 1998 | Immunopharmacol Immunotoxicol | pmid:9653668 |
| Silber RE et al. | Comparison of the effect of FK 506 and alpha/beta-T-cell antibody R73 on transplant vascular sclerosis after heterotopic rat heart transplantation. | 1998 | Transplant. Proc. | pmid:9636398 |
| Ohye H et al. | Effects of immunosuppressant agents on growth hormone release and gene expression. | 1998 | Endocr. J. | pmid:9790238 |
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