| MeSH term | MeSH ID | Detail |
|---|---|---|
| Denys-Drash Syndrome | D030321 | 1 associated lipids |
| Akinetic Mutism | D000405 | 1 associated lipids |
| Sleep Apnea, Central | D020182 | 1 associated lipids |
| Orchitis | D009920 | 1 associated lipids |
| Phyllodes Tumor | D003557 | 1 associated lipids |
| Meningitis, Fungal | D016921 | 1 associated lipids |
| Malocclusion, Angle Class II | D008312 | 1 associated lipids |
| Cardiomyopathy, Restrictive | D002313 | 1 associated lipids |
| Paraparesis, Tropical Spastic | D015493 | 1 associated lipids |
| Neurodermatitis | D009450 | 1 associated lipids |
tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (2)
- Am. J. Physiol. Renal Physiol. (1)
- Drug Metab. Dispos. (1)
- Others (1)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Wiederrecht GJ et al. | Mechanism of action of rapamycin: new insights into the regulation of G1-phase progression in eukaryotic cells. | 1995 | Prog Cell Cycle Res | pmid:9552353 |
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| Bersztel A et al. | Deoxyspergualin is synergistic with cyclosporin A, but not with FK506 in a rat heart allograft transplantation model. | 1995 | Transplant. Proc. | pmid:8540095 |
| Jonas S et al. | Rejection episodes after liver transplantation during primary immunosuppression with FK506 or a cyclosporine-based regimen: a controlled, prospective, randomized trial. | 1995 | Clin Transplant | pmid:8541635 |
| Andoh TF et al. | Functional and structural characteristics of experimental FK 506 nephrotoxicity. | 1995 | Clin. Exp. Pharmacol. Physiol. | pmid:8542679 |
| Fukunaga T et al. | Osteogenesis in xenogeneic bone transplantation, using an immunosuppressant. Rabbit-rat experiments. | 1995 | Acta Orthop Scand | pmid:8553828 |
| Ryffel B et al. | Interleukin-2 receptor (CD25) upregulation on human T-lymphocytes: sensitivity to immunosuppressants is defined by the mode of T-lymphocyte activation. | 1995 | Immunopharmacology | pmid:8557519 |
| Chaudhuri B et al. | The interaction between the catalytic A subunit of calcineurin and its autoinhibitory domain, in the yeast two-hybrid system, is disrupted by cyclosporin A and FK506. | 1995 | FEBS Lett. | pmid:7528690 |
| Sandborn WJ et al. | Early cellular rejection after orthotopic liver transplantation correlates with low concentrations of FK506 in hepatic tissue. | 1995 | Hepatology | pmid:7528712 |
| Coghlan VM et al. | Association of protein kinase A and protein phosphatase 2B with a common anchoring protein. | 1995 | Science | pmid:7528941 |
| Marx SO et al. | Rapamycin-FKBP inhibits cell cycle regulators of proliferation in vascular smooth muscle cells. | 1995 | Circ. Res. | pmid:7532117 |
| Söderdahl G et al. | FK 506 improves recovery of bile secretion following orthotopic liver transplantation in man. | 1995 | Transplant. Proc. | pmid:7533362 |
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| Hemenway CS et al. | vph6 mutants of Saccharomyces cerevisiae require calcineurin for growth and are defective in vacuolar H(+)-ATPase assembly. | 1995 | Genetics | pmid:8582630 |
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| Saito S et al. | The pattern of rejection and susceptibility to different kinds of immunosuppression after combined liver, duodenum, and pancreas transplantation in swine--immunosuppressive drugs versus ex vivo immunomodulation of the allograft. | 1995 | Transplant. Proc. | pmid:7533420 |
| Tashiro H et al. | Monitoring for engraftment of rat orthotopic liver transplantation by semiquantitative PCR. | 1995 | Transplant. Proc. | pmid:7533421 |
| Shirakata Y et al. | The minimum graft size for successful orthotopic partial liver transplantation in the canine model. | 1995 | Transplant. Proc. | pmid:7533422 |
| Kumano K et al. | Role of endothelin in FK 506-induced renal hypoperfusion in rats. | 1995 | Transplant. Proc. | pmid:7533423 |
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| Ikeda H and Fujiwara K | Cyclosporin A and FK-506 in inhibition of rat Ito cell activation in vitro. | 1995 | Hepatology | pmid:7535735 |
| Grimmond S et al. | Exclusion of the 13-kDa rapamycin binding protein gene (FKBP2) as a candidate gene for multiple endocrine neoplasia type 1. | 1995 | Hum. Genet. | pmid:7535744 |
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| Atkison P et al. | Hypertrophic cardiomyopathy associated with tacrolimus in paediatric transplant patients. | 1995 | Lancet | pmid:7535875 |
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| Dix SP et al. | Re: Severe interaction between methotrexate and a macrolide-like antibiotic. | 1995 | J. Natl. Cancer Inst. | pmid:7563209 |
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| Kobayashi I et al. | Combination therapy with tacrolimus and betamethasone for a patient with X-linked auto-immune enteropathy. | 1995 | Eur. J. Pediatr. | pmid:7556338 |
| Mañez R et al. | Anomalous pattern of IgG antibody response to primary cytomegalovirus infection after solid organ retransplantation. | 1995 | Transplantation | pmid:7537400 |
| Adachi M et al. | IL-2-induced gene expression of protein-tyrosine phosphatase LC-PTP requires acidic and serine-rich regions within IL-2 receptor beta chain. | 1995 | FEBS Lett. | pmid:7556630 |
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| Woodle ES et al. | FK 506 rescue therapy for hepatic allograft rejection: experience with an aggressive approach. | 1995 | Clin Transplant | pmid:7537988 |
| Mills RA et al. | Topical FK-506 prevents experimental corneal allograft rejection. | 1995 | Cornea | pmid:7538061 |
| Lee TK et al. | Postoperative selective bowel decontamination prevents gram-negative bacterial translocation in small-bowel graft recipients. | 1995 | J. Surg. Res. | pmid:7538186 |
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| Lochmüller H et al. | Immunosuppression by FK506 markedly prolongs expression of adenovirus-delivered transgene in skeletal muscles of adult dystrophic [mdx] mice. | 1995 | Biochem. Biophys. Res. Commun. | pmid:7544122 |
| Deschler DG et al. | Posttransplantation lymphoproliferative disorder in patients under primary tacrolimus (FK 506) immunosuppression. | 1995 | Arch. Otolaryngol. Head Neck Surg. | pmid:7544136 |
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| Bolman RM | Advantage--FK 506: reduced chronic rejection for lung transplant recipients. | 1995 | Ann. Thorac. Surg. | pmid:7545888 |
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| Okamoto M et al. | In situ proliferating status of mononuclear cells in rat small bowel grafts. | 1995 | Int J Exp Pathol | pmid:7547442 |
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| Barkholt LM et al. | Epstein-Barr virus DNA in serum after liver transplantation--surveillance of viral activity during treatment with different immunosuppressive agents. | 1996 | Transpl. Int. | pmid:8875785 |
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