| MeSH term | MeSH ID | Detail |
|---|---|---|
| Protoporphyria, Erythropoietic | D046351 | 1 associated lipids |
| Colitis, Collagenous | D046729 | 1 associated lipids |
| Hepatic Insufficiency | D048550 | 1 associated lipids |
| Diabetes Complications | D048909 | 4 associated lipids |
| Dyslipidemias | D050171 | 7 associated lipids |
| Atherosclerosis | D050197 | 85 associated lipids |
| Granulomatosis, Orofacial | D051261 | 2 associated lipids |
| Lymphohistiocytosis, Hemophagocytic | D051359 | 1 associated lipids |
| Renal Insufficiency | D051437 | 8 associated lipids |
| Delayed Graft Function | D051799 | 2 associated lipids |
tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (2)
- Am. J. Physiol. Renal Physiol. (1)
- Drug Metab. Dispos. (1)
- Others (1)
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Huang K et al. | Novel role for NFAT3 in ERK-mediated regulation of CXCR4. | 2014 | PLoS ONE | pmid:25514788 |
| Amorim J et al. | Tacrolimus-induced neutropenia in a cardiac transplant patient. | 2014 | Pediatr Transplant | pmid:24384051 |
| Saso S et al. | Uterine allotransplantation in a rabbit model using aorto-caval anastomosis: a long-term viability study. | 2014 | Eur. J. Obstet. Gynecol. Reprod. Biol. | pmid:25306223 |
| Meyer KC et al. | An international ISHLT/ATS/ERS clinical practice guideline: diagnosis and management of bronchiolitis obliterans syndrome. | 2014 | Eur. Respir. J. | pmid:25359357 |
| Ahmed S et al. | Photocleavable dimerizer for the rapid reversal of molecular trap antagonists. | 2014 | J. Biol. Chem. | pmid:24421317 |
| Al-Amri AM | Long-term follow-up of tacrolimus ointment for treatment of atopic keratoconjunctivitis. | 2014 | Am. J. Ophthalmol. | pmid:24439439 |
| Kim JR et al. | 20-O-β-D-glucopyranosyl-20(S)-protopanaxadiol-fortified ginseng extract attenuates the development of atopic dermatitis-like symptoms in NC/Nga mice. | 2014 | J Ethnopharmacol | pmid:24269244 |
| Lin Y et al. | PERK activation preserves the viability and function of remyelinating oligodendrocytes in immune-mediated demyelinating diseases. | 2014 | Am. J. Pathol. | pmid:24269558 |
| Koren G and Rieder M | Measuring oral bioavailability of tacrolimus. | 2014 | Pediatr Transplant | pmid:25250966 |
| Ueda K et al. | Early corticosteroid withdrawal in the real world: a long-term analysis of kidney transplant recipients from the Mycophenolic Acid Observational Renal Transplant Registry. | 2014 | Ann. Transplant. | pmid:24535029 |
| Görzer I et al. | Plasma DNA levels of Torque teno virus and immunosuppression after lung transplantation. | 2014 | J. Heart Lung Transplant. | pmid:24559947 |
| Barnieh L et al. | The cost of kidney transplant over time. | 2014 | Prog Transplant | pmid:25193726 |
| Guy S et al. | Successful treatment of acute severe graft-versus-host-disease in a pancreas-after-kidney transplant recipient: case report. | 2014 | Transplant. Proc. | pmid:25179161 |
| Yuan C et al. | A simple and robust LC-MS/MS method for measuring sirolimus and everolimus in whole blood. | 2014 | Bioanalysis | pmid:25077621 |
| Beermann KJ et al. | Tacrolimus dose requirements in African-American and Caucasian kidney transplant recipients on mycophenolate and prednisone. | 2014 | Clin Transplant | pmid:24754564 |
| Matia I et al. | Immunosuppressive protocol with delayed use of low-dose tacrolimus after aortic transplantation suppresses donor-specific anti-MHC class I and class II antibody production in rats. | 2014 | Ann. Transplant. | pmid:24815872 |
| Harada N et al. | [Follow-up study on patients with vernal keratoconjunctivitis undergoing topical 0.1% tacrolimus treatment]. | 2014 | Nippon Ganka Gakkai Zasshi | pmid:24864437 |
| Izumi Y et al. | Safety of tacrolimus treatment during pregnancy and lactation in systemic lupus erythematosus: a report of two patients. | 2014 | Tohoku J. Exp. Med. | pmid:25175032 |
| Anderson JS et al. | Statistical allosteric coupling to the active site indole ring flip equilibria in the FK506-binding domain. | 2014 | Biophys. Chem. | pmid:25016286 |
| Lunde I et al. | The influence of CYP3A, PPARA, and POR genetic variants on the pharmacokinetics of tacrolimus and cyclosporine in renal transplant recipients. | 2014 | Eur. J. Clin. Pharmacol. | pmid:24658827 |
| Webster P et al. | Tacrolimus is an effective treatment for lupus nephritis in pregnancy. | 2014 | Lupus | pmid:24928830 |
| Carbajo-Lozoya J et al. | Human coronavirus NL63 replication is cyclophilin A-dependent and inhibited by non-immunosuppressive cyclosporine A-derivatives including Alisporivir. | 2014 | Virus Res. | pmid:24566223 |
| Ren Y et al. | Tolerogenic dendritic cells modified by tacrolimus suppress CD4(+) T-cell proliferation and inhibit collagen-induced arthritis in mice. | 2014 | Int. Immunopharmacol. | pmid:24836681 |
| Li H et al. | A promising approach of overcoming the intrinsic resistance of Candida krusei to fluconazole (FLC)--combining tacrolimus with FLC. | 2014 | FEMS Yeast Res. | pmid:24830342 |
| Welzl K et al. | Effect of different immunosuppressive drugs on immune cells from young and old healthy persons. | 2014 | Gerontology | pmid:24434865 |
| Yang LM et al. | Experimental research on end-to-side anastomosis of peripheral nerves and effect of FK506 on end-to-side anastomosis. | 2014 | Bratisl Lek Listy | pmid:25573729 |
| Taimur S et al. | Donor T-cell chimerism and early post-transplant cytomegalovirus viremia in patients treated with myeloablative allogeneic hematopoietic stem cell transplant. | 2014 | Transpl Infect Dis | pmid:24251680 |
| Stewart JI et al. | Reverse halo sign on chest imaging in a renal transplant recipient. | 2014 | Transpl Infect Dis | pmid:24289813 |
| Nacif LS et al. | An analysis of tacrolimus-related complications in the first 30 days after liver transplantation. | 2014 | Clinics (Sao Paulo) | pmid:25518032 |
| Nishimoto K et al. | [Case of organizing pneumonia associated with sweet's syndrome]. | 2014 | Arerugi | pmid:25163580 |
| Elens L et al. | Clinical implementation of pharmacogenetics in kidney transplantation: calcineurin inhibitors in the starting blocks. | 2014 | Br J Clin Pharmacol | pmid:24118098 |
| Heilman RL et al. | Delayed allograft inflammation following alemtuzumab induction for kidney transplantation. | 2013 Sep-Oct | Clin Transplant | pmid:23924146 |
| Benoit S and Hamm H | Psoriasis from a prosthesis: unusual Koebner phenomenon in a girl with autoamputation of the leg. | 2013 Sep-Oct | Pediatr Dermatol | pmid:23360396 |
| Zahdi MR et al. | Erosive pustular dermatosis of the scalp successfully treated with oral prednisone and topical tacrolimus. | 2013 Sep-Oct | An Bras Dermatol | pmid:24173187 |
| Riva N et al. | [Pharmacovigilance of calcineurin inhibitor in peidatric kidney and liver transplantation]. | 2013 Nov-Dec | Farm Hosp | pmid:24256007 |
| Brodrick B et al. | Influence of treatments on prognosis for vulvar lichen sclerosus: facts and controversies. | 2013 Nov-Dec | Clin. Dermatol. | pmid:24160287 |
| Bloom RD et al. | A randomized, crossover pharmacokinetic study comparing generic tacrolimus vs. the reference formulation in subpopulations of kidney transplant patients. | 2013 Nov-Dec | Clin Transplant | pmid:24118450 |
| Labirua-Iturburu A et al. | Calcineurin inhibitors in a cohort of patients with antisynthetase-associated interstitial lung disease. | 2013 May-Jun | Clin. Exp. Rheumatol. | pmid:23465087 |
| Chen SY et al. | Individualization of tacrolimus dosage basing on cytochrome P450 3A5 polymorphism--a prospective, randomized, controlled study. | 2013 May-Jun | Clin Transplant | pmid:23432535 |
| Ramirez CB et al. | Completely steroid-free immunosuppression in liver transplantation: a randomized study. | 2013 May-Jun | Clin Transplant | pmid:23621629 |
| Krishna N et al. | Tacrolimus-induced paranoid delusions and fugue-like state. | 2013 May-Jun | Gen Hosp Psychiatry | pmid:22959421 |
| He L et al. | Treatment of idiopathic membranous nephropathy with combination of low-dose tacrolimus and corticosteroids. | 2013 May-Jun | J. Nephrol. | pmid:22956434 |
| Kanzelmeyer NK et al. | Correlations with six-month protocol biopsy findings in pediatric transplant recipients on low- and regular-dose CNI regimens. | 2013 Mar-Apr | Clin Transplant | pmid:23414365 |
| Tiwari R et al. | Enhancements in healthcare information technology systems: customizing vendor-supplied clinical decision support for a high-risk patient population. | 2013 Mar-Apr | J Am Med Inform Assoc | pmid:22813760 |
| Albekairy A et al. | Cytochrome P450 3A4FNx011B as pharmacogenomic predictor of tacrolimus pharmacokinetics and clinical outcome in the liver transplant recipients. | 2013 Mar-Apr | Saudi J Gastroenterol | pmid:23481136 |
| LaMattina JC et al. | Native kidney function following liver transplantation using calcineurin inhibitors: single-center analysis with 20 years of follow-up. | 2013 Mar-Apr | Clin Transplant | pmid:23294013 |
| Alfson ED et al. | Lysis of catatonic withdrawal by propofol in a bone-marrow transplant recipient with adenovirus limbic encephalitis. | 2013 Mar-Apr | Psychosomatics | pmid:22705183 |
| Yoshida EM et al. | Canadian national retrospective chart review comparing the long term effect of cyclosporine vs. tacrolimus on clinical outcomes in patients with post-liver transplantation hepatitis C virus infection. | 2013 Mar-Apr | Ann Hepatol | pmid:23396740 |
| Castillo G et al. | [Acute cellular rejection in a liver transplantation patient due to changing the brand of a generic immunosuppressant]. | 2013 Jul-Sep | Rev Gastroenterol Mex | pmid:23866966 |
| Bechstein WO et al. | A comparative, randomized trial of concentration-controlled sirolimus combined with reduced-dose tacrolimus or standard-dose tacrolimus in renal allograft recipients. | 2013 Jul-Aug | Transplant. Proc. | pmid:23953523 |
| Zhao YJ et al. | Late, severe, noninfectious diarrhea after renal transplantation: high-risk factors, therapy, and prognosis. | 2013 Jul-Aug | Transplant. Proc. | pmid:23953533 |
| Weiler N et al. | Tacrolimus effects and side effects after liver transplantation: is there a difference between immediate and extended release? | 2013 Jul-Aug | Transplant. Proc. | pmid:23953543 |
| Stringa P et al. | Ischemic preconditioning and tacrolimus pretreatment as strategies to attenuate intestinal ischemia-reperfusion injury in mice. | 2013 Jul-Aug | Transplant. Proc. | pmid:23953566 |
| Tachibana A et al. | Repopulation of the immunosuppressed retrorsine-treated infant rat liver with human hepatocytes. | 2013 Jul-Aug | Xenotransplantation | pmid:23683097 |
| Favi E et al. | Tacrolimus plus mycophenolate mofetil vs. cyclosporine plus everolimus in deceased donor kidney transplant recipients: three-yr results of a single-center prospective clinical trial. | 2013 Jul-Aug | Clin Transplant | pmid:23710603 |
| Eberlin M et al. | Increased medication compliance of liver transplant patients switched from a twice-daily to a once-daily tacrolimus-based immunosuppressive regimen. | 2013 Jul-Aug | Transplant. Proc. | pmid:23726723 |
| Satyanarayan HS et al. | Efficacy and tolerability of combined treatment with NB-UVB and topical tacrolimus versus NB-UVB alone in patients with vitiligo vulgaris: a randomized intra-individual open comparative trial. | 2013 Jul-Aug | Indian J Dermatol Venereol Leprol | pmid:23760325 |
| Babalola O and Strober BE | Treatment of atopic dermatitis in pregnancy. | 2013 Jul-Aug | Dermatol Ther | pmid:23914886 |
| Conti R et al. | Jessner-Kanof disease: two effective and sure therapeutic options. | 2013 Jul-Aug | Dermatol Ther | pmid:23914897 |
| Chakkera HA et al. | Genetic differences in Native Americans and tacrolimus dosing after kidney transplantation. | 2013 Jan-Feb | Transplant. Proc. | pmid:23375287 |
| Tian Ch et al. | B- and T-lymphocyte attenuator/herpes virus entry mediator as early indicators for acute rejection following kidney transplantation. | 2013 Jan-Feb | Transplant. Proc. | pmid:23375291 |
| Yao B et al. | The incidence of posttransplantation diabetes mellitus during follow-up in kidney transplant recipients and relationship to Fok1 vitamin D receptor polymorphism. | 2013 Jan-Feb | Transplant. Proc. | pmid:23375298 |
| Miyazaki T et al. | Two case reports of successful withdrawal of mycofenolate mofetil after living donor lobar lung transplantation. | 2013 Jan-Feb | Transplant. Proc. | pmid:23375323 |
| Chang HY et al. | Long-term follow-up of arrhythmia characteristics and clinical outcomes in heart transplant patients. | 2013 Jan-Feb | Transplant. Proc. | pmid:23375324 |
| Al Nahdi N et al. | First successful treatment of post-liver transplant hepatitis C fibrosing cholestatic hepatitis with boceprevir, peginterferon and ribavirin in a pre-transplant null responder. | 2013 Jan-Feb | Ann Hepatol | pmid:23293209 |
| Seco-Melantuche R et al. | [Incidence of drug-induced thrombocytopenia in hospitalized patients]. | 2013 Jan-Feb | Farm Hosp | pmid:23461497 |
| Rao V et al. | A non-induction renal sparing approach after liver transplantation: high dose mycophenolate mofetil with delayed, low-dose tacrolimus. | 2013 Jan-Feb | Transplant. Proc. | pmid:23267806 |
| Langone A et al. | Does reduction in mycophenolic acid dose compromise efficacy regardless of tacrolimus exposure level? An analysis of prospective data from the Mycophenolic Renal Transplant (MORE) Registry. | 2013 Jan-Feb | Clin Transplant | pmid:22861144 |
| Shiba H et al. | Switching from tacrolimus to cyclosporine A to prevent primary biliary cirrhosis recurrence after living-donor liver transplantation. | 2013 Apr-Jun | Int Surg | pmid:23701152 |
| Adamu B et al. | New-onset diabetes after renal transplantation: a case series as seen in a Nigerian kidney transplant population. | 2013 Apr-Jun | Niger J Clin Pract | pmid:23563475 |
| Cangemi G et al. | Comparison of antibody-conjugated magnetic immunoassay and liquid chromatography-tandem mass spectrometry for the measurement of cyclosporine and tacrolimus in whole blood. | 2013 Apr-Jun | Int J Immunopathol Pharmacol | pmid:23755756 |
| Yoshikawa Y et al. | [Pre-evening meal administration of tacrolimus improved refractory ocular symptoms in two young children with latent general myasthenia gravis]. | 2013 | No To Hattatsu | pmid:23951946 |
| Preidl RH et al. | Clopidogrel reduces post-transplant obliterative bronchiolitis. | 2013 | Transpl. Int. | pmid:23952051 |
| Mignogna MD et al. | Clinical behaviour and long-term therapeutic response in orofacial granulomatosis patients treated with intralesional triamcinolone acetonide injections alone or in combination with topical pimecrolimus 1%. | 2013 | J. Oral Pathol. Med. | pmid:22784292 |
| Westland T et al. | Treatment of atopic keratoconjunctivitis in patients with atopic dermatitis: is ocular application of tacrolimus an option? | 2013 | J Eur Acad Dermatol Venereol | pmid:23106347 |
| Pan F et al. | [Protective effect of tacrolimus postconditioning on oxidative stress injury provoked by spinal cord ischemia-reperfusion in rats]. | 2013 | Zhonghua Yi Xue Za Zhi | pmid:24548402 |
| Mesar I et al. | Rescue therapy with sirolimus in a renal transplant recipient with tacrolimus-induced hepatotoxicity. | 2013 | Ren Fail | pmid:24028307 |
| Dong QE et al. | [Inhibitory effects of tacrolimus on effector T cells from patients with severe aplastic anemia]. | 2013 | Zhonghua Yi Xue Za Zhi | pmid:24028719 |
| Bourdeaux C et al. | Prope tolerance after pediatric liver transplantation. | 2013 | Pediatr Transplant | pmid:23171043 |
| Prucha H et al. | Pimecrolimus, a topical calcineurin inhibitor used in the treatment of atopic eczema. | 2013 | Expert Opin Drug Metab Toxicol | pmid:23876065 |
| Kim CH et al. | 850nm light-emitting-diode phototherapy plus low-dose tacrolimus (FK-506) as combination therapy in the treatment of Dermatophagoides farinae-induced atopic dermatitis-like skin lesions in NC/Nga mice. | 2013 | J. Dermatol. Sci. | pmid:23810774 |
| Rickels MR et al. | Improvement in insulin sensitivity after human islet transplantation for type 1 diabetes. | 2013 | J. Clin. Endocrinol. Metab. | pmid:24085506 |
| Renner B et al. | Cyclosporine induces endothelial cell release of complement-activating microparticles. | 2013 | J. Am. Soc. Nephrol. | pmid:24092930 |
| Michel S et al. | Renal recovery after conversion to an everolimus-based immunosuppression in early and late heart transplant recipients: a 12-month analysis. | 2013 | Exp Clin Transplant | pmid:24128136 |
| Kim Y et al. | Patients with persistent new-onset diabetes after transplantation have greater weight gain after kidney transplantation. | 2013 | J. Korean Med. Sci. | pmid:24133345 |
| Vichyanond P and Kosrirukvongs P | Use of cyclosporine A and tacrolimus in treatment of vernal keratoconjunctivitis. | 2013 | Curr Allergy Asthma Rep | pmid:23625179 |
| Wang Y et al. | Micelles of methoxy poly(ethylene glycol)-poly(epsilon-caprolactone) as a novel drug delivery vehicle for tacrolimus. | 2013 | J Biomed Nanotechnol | pmid:23627041 |
| Axelsson J et al. | Scavengers of reactive oxygen species, paracalcitol, RhoA, and Rac-1 inhibitors and tacrolimus inhibit angiotensin II-induced actions on glomerular permeability. | 2013 | Am. J. Physiol. Renal Physiol. | pmid:23657856 |
| Lee Sr et al. | Angiotensinogen polymorphisms and post-transplantation diabetes mellitus in Korean renal transplant subjects. | 2013 | Kidney Blood Press. Res. | pmid:23594830 |
| Casanova JR et al. | Rapid hippocampal network adaptation to recurring synchronous activity--a role for calcineurin. | 2013 | Eur. J. Neurosci. | pmid:23879713 |
| Eguchi R et al. | FK506 induces endothelial dysfunction through attenuation of Akt and ERK1/2 independently of calcineurin inhibition and the caspase pathway. | 2013 | Cell. Signal. | pmid:23707520 |
| Fitzgerald RT et al. | Isolated leptomeningeal enhancement in tacrolimus-associated posterior reversible encephalopathy syndrome. | 2013 | Pediatr. Neurol. | pmid:23290027 |
| van Maarseveen EM et al. | Pretransplantation pharmacokinetic curves of tacrolimus in HIV-infected patients on ritonavir-containing cART: a pilot study. | 2013 | Transplantation | pmid:23250333 |
| Han N et al. | Prediction of the tacrolimus population pharmacokinetic parameters according to CYP3A5 genotype and clinical factors using NONMEM in adult kidney transplant recipients. | 2013 | Eur. J. Clin. Pharmacol. | pmid:22660440 |
| Oteo I et al. | Tacrolimus pharmacokinetics in the early post-liver transplantation period and clinical applicability via Bayesian prediction. | 2013 | Eur. J. Clin. Pharmacol. | pmid:22660442 |
| Bashratyan R et al. | Insulinoma-released exosomes activate autoreactive marginal zone-like B cells that expand endogenously in prediabetic NOD mice. | 2013 | Eur. J. Immunol. | pmid:23817982 |
| Yin H et al. | Enhancing pancreatic Beta-cell regeneration in vivo with pioglitazone and alogliptin. | 2013 | PLoS ONE | pmid:23762423 |
| Tie X et al. | NFAT1 is highly expressed in, and regulates the invasion of, glioblastoma multiforme cells. | 2013 | PLoS ONE | pmid:23762456 |
| Rice SA et al. | Topical tacrolimus 0.1% ointment for treatment of cutaneous Crohn's Disease. | 2013 | BMC Res Notes | pmid:23331739 |
| Kanda J et al. | Pre-engraftment syndrome after myeloablative dual umbilical cord blood transplantation: risk factors and response to treatment. | 2013 | Bone Marrow Transplant. | pmid:23334274 |