tacrolimus

Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.

Cross Reference

Introduction

To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with tacrolimus?

tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with tacrolimus

MeSH term MeSH ID Detail
Nocturnal Myoclonus Syndrome D020189 1 associated lipids
Uveomeningoencephalitic Syndrome D014607 1 associated lipids
Pseudohypoaldosteronism D011546 1 associated lipids
Dendritic Cell Sarcoma, Interdigitating D054739 1 associated lipids
Polymyositis D017285 1 associated lipids
Scorpion Stings D065008 1 associated lipids
Rotavirus Infections D012400 1 associated lipids
Netherton Syndrome D056770 1 associated lipids
Lymphocytic Choriomeningitis D008216 1 associated lipids
Erythroplasia D004919 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with tacrolimus

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with tacrolimus?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with tacrolimus?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with tacrolimus?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with tacrolimus?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with tacrolimus?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with tacrolimus

Download all related citations
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Authors Title Published Journal PubMed Link
Azuma H et al. Atypical Epstein-Barr virus infection during and after intermittent FK506 therapy. 1997 Acta Paediatr Jpn pmid:9141259
Bienemann K et al. Topical tacrolimus is effective against eczema in Wiskott-Aldrich syndrome (WAS). 2007 Acta Paediatr. pmid:17429928
Sinha R and Marks SD Tacrolimus toxicity secondary to diarrhoea in nephrotic syndrome. 2013 Acta Paediatr. pmid:23573873
Isidor B et al. Hyperzincemia and hypercalprotectinemia: unsuccessful treatment with tacrolimus. 2009 Acta Paediatr. pmid:18983438
Marlaka JR et al. Tacrolimus without or with the addition of conventional immunosuppressive treatment in juvenile autoimmune hepatitis. 2012 Acta Paediatr. pmid:22646819
Gradman J and Wolthers OD Short-term growth in children with eczema during treatment with topical mometasone furoate and tacrolimus. 2007 Acta Paediatr. pmid:17590198
Puzik A et al. Effects of ciclosporin A, tacrolimus and sirolimus on cytokine production in neonatal immune cells. 2007 Acta Paediatr. pmid:17880416
Luo X et al. Prediction of tacrolimus metabolism and dosage requirements based on CYP3A4 phenotype and CYP3A5(*)3 genotype in Chinese renal transplant recipients. 2016 Acta Pharmacol. Sin. pmid:26924289
Lu YX et al. A population pharmacokinetic study of tacrolimus in healthy Chinese volunteers and liver transplant patients. 2015 Acta Pharmacol. Sin. pmid:25500866
Chen JC and Ma P Mechanism of FK506-induced renal hypoperfusion and its reversion in rats. 2001 Acta Pharmacol. Sin. pmid:11749797