tacrolimus

Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.

Cross Reference

Introduction

To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with tacrolimus?

tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with tacrolimus

MeSH term MeSH ID Detail
IgG Deficiency D017099 1 associated lipids
Deltaretrovirus Infections D006800 1 associated lipids
Dendritic Cell Sarcoma, Interdigitating D054739 1 associated lipids
Polymyositis D017285 1 associated lipids
Scorpion Stings D065008 1 associated lipids
Rotavirus Infections D012400 1 associated lipids
Netherton Syndrome D056770 1 associated lipids
Pseudohypoaldosteronism D011546 1 associated lipids
Arm Injuries D001134 1 associated lipids
Intussusception D007443 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with tacrolimus

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with tacrolimus?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with tacrolimus?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with tacrolimus?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with tacrolimus?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with tacrolimus?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with tacrolimus

Download all related citations
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Authors Title Published Journal PubMed Link
Basadonna GP et al. Pancreas after kidney transplantation: HLA mismatch does not preclude success. 1997 Feb-Mar Transplant. Proc. pmid:9123470
Gruessner AC et al. Solitary pancreas transplants: improving results and factors that influence outcome. 1997 Feb-Mar Transplant. Proc. pmid:9123468
Stratta RJ Simultaneous use of tacrolimus and mycophenolate mofetil in combined pancreas-kidney transplant recipients: a multi-center report. The FK/MMF Multi-Center Study Group. 1997 Feb-Mar Transplant. Proc. pmid:9123463
Hariharan S et al. Long-term renal and pancreas function with tacrolimus rescue therapy following kidney/pancreas transplantation. 1997 Feb-Mar Transplant. Proc. pmid:9123462
el-Ghoroury M et al. Efficacy and safety of tacrolimus versus cyclosporine in kidney and pancreas transplant recipients. 1997 Feb-Mar Transplant. Proc. pmid:9123461
Corry RJ et al. Pancreas transplantation with enteric drainage under tacrolimus induction therapy. 1997 Feb-Mar Transplant. Proc. pmid:9123457
Millis JM et al. Tacrolimus treatment of steroid-resistant rejection provides economic advantages compared with OKT3 therapy. 1997 Feb-Mar Transplant. Proc. pmid:9123421
Walgenbach KJ et al. Immunocytes of composite tissue allografts express elevated levels of TGF beta mRNA and protein during chronic rejection. 1997 Feb-Mar Transplant. Proc. pmid:9123418
Guo Z et al. Leflunomide, a potential immunosuppressant for pancreatic islet transplantation. 1997 Feb-Mar Transplant. Proc. pmid:9123314
Grochowicz PM et al. Synergistic interaction between castanospermine and tacrolimus in a rat heart allograft model. 1997 Feb-Mar Transplant. Proc. pmid:9123296
Kumano K et al. Role of the transforming growth factor and monocyte chemoattractant protein in FK506-induced nephropathy in the rat. 1997 Feb-Mar Transplant. Proc. pmid:9123293
Wijnen RM et al. Thymus atrophy in the nonhuman primate by FK506: an immunohistochemical study. 1997 Feb-Mar Transplant. Proc. pmid:9123292
Tashiro H et al. Correlation of high-level microchimerism with graft acceptance in rat liver transplantation. 1997 Feb-Mar Transplant. Proc. pmid:9123287
Ota H et al. Intrathymic microchimerism predicts rejection response in allograft recipients. 1997 Feb-Mar Transplant. Proc. pmid:9123279
Burke GW et al. Donor bone marrow infusion in simultaneous pancreas/kidney transplantation with OKT3 induction: evidence for augmentation of chimerism. 1997 Feb-Mar Transplant. Proc. pmid:9123275
Gassel HJ et al. Selective immunosuppression induces tolerance after liver transplantation: an immunohistochemical and cytofluorographic analysis of the graft and recipient immune system. 1997 Feb-Mar Transplant. Proc. pmid:9123253
pmid:9123237
Nakajima H and Oka T Analysis of biochemical and biological functions of Fas-ligand (FasL) and Fas on activated T cells in allo-immune response. 1997 Feb-Mar Transplant. Proc. pmid:9123217
Li W et al. High-dose cellular IL-10 exacerbates rejection and reverses effects of cyclosporine and tacrolimus in Mouse cardiac transplantation. 1997 Feb-Mar Transplant. Proc. pmid:9123209
Zipperle S et al. Impaired T-cell IL-10 secretion and CD4 helper function in liver transplant patients treated with tacrolimus. 1997 Feb-Mar Transplant. Proc. pmid:9123208
Morozumi K et al. Electron-microscopic peritubular capillary lesion is a specific and useful diagnostic indicator for chronic rejection of renal allografts showing less specific morphologic lesions in the cyclosporine era. 1997 Feb-Mar Transplant. Proc. pmid:9123167
Misao T et al. Effect of donor splenocyte transfusion with a simultaneous single injection of tacrolimus on lung allografts. 1997 Feb-Mar Transplant. Proc. pmid:9123153
Meiser BM et al. Tacrolimus (FK506) proves superior to OKT3 for treating episodes of persistent rejection following intrathoracic transplantation. 1997 Feb-Mar Transplant. Proc. pmid:9123150
Katoh H et al. Effectiveness of 15-deoxyspergualin on steroid-resistant acute rejection in living related liver transplantation. 1997 Feb-Mar Transplant. Proc. pmid:9123125
Gavlik A et al. Mycophenolate mofetil rescue therapy in liver transplant recipients. 1997 Feb-Mar Transplant. Proc. pmid:9123124
Busuttil RW and Holt CD Tacrolimus (FK506) is superior to cyclosporine in liver transplantation. 1997 Feb-Mar Transplant. Proc. pmid:9123119
Khanna A et al. Cardiac changes at autopsy in adult liver transplant recipients under tacrolimus. 1997 Feb-Mar Transplant. Proc. pmid:9123118
Ko S et al. Predominant role of local immunosuppressive effect in enhanced efficacy of liposomal FK506 in organ transplantation. 1997 Feb-Mar Transplant. Proc. pmid:9123117
Platz KP et al. Impact of immunosuppression and acute rejection on hepatitis B recurrence. 1997 Feb-Mar Transplant. Proc. pmid:9123107
Rayes N et al. Distribution of lymphocyte subtypes in liver transplant recipients. 1997 Feb-Mar Transplant. Proc. pmid:9123103
Marino IR et al. Preoperative assessment of risk in liver transplantation: a multivariate analysis in 2376 cases of the UW era. 1997 Feb-Mar Transplant. Proc. pmid:9123079
Cho JH et al. Chronic rejection in pediatric liver transplantation. 1997 Feb-Mar Transplant. Proc. pmid:9123078
Shapiro R Tacrolimus (FK-506) in kidney transplantation. 1997 Feb-Mar Transplant. Proc. pmid:9123077
Bonatti H et al. Liver transplantation for acute liver failure in children under 1 year of age. 1997 Feb-Mar Transplant. Proc. pmid:9123068
Sellers M et al. Incidence of late acute rejection and progression to chronic rejection in pediatric liver recipients. 1997 Feb-Mar Transplant. Proc. pmid:9123065
Zucker K et al. Augmentation of mycophenolate mofetil pharmacokinetics in renal transplant patients receiving Prograf and CellCept in combination therapy. 1997 Feb-Mar Transplant. Proc. pmid:9123027
Lyne JC et al. Cadaveric renal transplantation against a positive historic crossmatch under tacrolimus immunosuppression: long-term follow-up. 1997 Feb-Mar Transplant. Proc. pmid:9123015
pmid:9123014
Naraghi RM et al. Long-term follow-up of tacrolimus rescue therapy for renal allograft rejection. 1997 Feb-Mar Transplant. Proc. pmid:9123013
Zhu Y et al. Prolongation of canine renal allograft survival by combining tacrolimus with antimetabolic agents. 1997 Feb-Mar Transplant. Proc. pmid:9123011
Cronin DC et al. Tacrolimus therapy for refractory renal allograft rejection: experience with steroid withdrawal. 1997 Feb-Mar Transplant. Proc. pmid:9123010
Jordan ML et al. Five-year experience with tacrolimus rescue for renal allograft rejection. 1997 Feb-Mar Transplant. Proc. pmid:9123009
Miller J et al. FK 506 in kidney transplantation: results of the U.S.A. randomized comparative phase III study. The FK 506 Kidney Transplant Study Group. 1997 Feb-Mar Transplant. Proc. pmid:9123008
Gaber LW et al. Renal histology with varying FK506 blood levels. 1997 Feb-Mar Transplant. Proc. pmid:9122955
Wu J et al. Reversal of multidrug resistance by tacrolimus hydrate. 1996 Methods Find Exp Clin Pharmacol pmid:9121220
Jacobson PA et al. Stability of tacrolimus in an extemporaneously compounded oral liquid. 1997 Am J Health Syst Pharm pmid:9117806
Eum SY et al. Inhibition by the immunosuppressive agent FK-506 of antigen-induced airways eosinophilia and bronchial hyperreactivity in mice. 1997 Br. J. Pharmacol. pmid:9117088
Singh N et al. Invasive fungal infections in liver transplant recipients receiving tacrolimus as the primary immunosuppressive agent. 1997 Clin. Infect. Dis. pmid:9114144
Mignat C Clinically significant drug interactions with new immunosuppressive agents. 1997 Drug Saf pmid:9113494
Ahsan N et al. Successful reversal of acute vascular rejection in a renal allograft with combined mycophenolate mofetil and tacrolimus as primary immunotherapy. 1997 Clin Transplant pmid:9113443