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FK506 nephrotoxicity: morphologic and physiologic characterization of a rat model. |
1995 |
Lab. Invest. |
pmid:8558840
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Gjertson DW et al. |
The relative effects of FK506 and cyclosporine on short- and long-term kidney graft survival. |
1995 |
Transplantation |
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Shirakata Y et al. |
Inhibitory effect of plasma FKBP12 on immunosuppressive activity of FK506. |
1995 |
Transplantation |
pmid:8545894
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Aoyama H et al. |
Successful treatment of resistant facial lesions of atopic dermatitis with 0.1% FK506 ointment. |
1995 |
Br. J. Dermatol. |
pmid:8547017
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Gharpure VS et al. |
Thrombotic thrombocytopenic purpura associated with FK506 following bone marrow transplantation. |
1995 |
Bone Marrow Transplant. |
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Koch K et al. |
CP-123,369: a potent, orally active immunosuppressive agent. |
1995 |
Inflamm. Res. |
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Lionetti P et al. |
Mucosal adaptation and destruction in response to lamina propria T cell activation in explants of human fetal intestine. |
1995 |
Adv. Exp. Med. Biol. |
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Ku YM et al. |
Compatibility of tacrolimus injection with cimetidine hydrochloride injection in 0.9% sodium chloride injection. |
1995 |
Am J Health Syst Pharm |
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Clardy J |
The chemistry of signal transduction. |
1995 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:7529414
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Braun W et al. |
Three-dimensional structure and actions of immunosuppressants and their immunophilins. |
1995 |
FASEB J. |
pmid:7529736
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Kawai M et al. |
Pyrrolidine dithiocarbamate inhibits intercellular adhesion molecule-1 biosynthesis induced by cytokines in human fibroblasts. |
1995 |
J. Immunol. |
pmid:7532665
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Venkataraman L et al. |
FK506 inhibits antigen receptor-mediated induction of c-rel in B and T lymphoid cells. |
1995 |
J. Exp. Med. |
pmid:7532676
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Wang CR et al. |
T cell receptor-mediated signaling events in CD4+CD8+ thymocytes undergoing thymic selection: requirement of calcineurin activation for thymic positive selection but not negative selection. |
1995 |
J. Exp. Med. |
pmid:7532685
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Cao W et al. |
Effects of rapamycin on growth factor-stimulated vascular smooth muscle cell DNA synthesis. Inhibition of basic fibroblast growth factor and platelet-derived growth factor action and antagonism of rapamycin by FK506. |
1995 |
Transplantation |
pmid:7532879
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Gaweco AS et al. |
Common and sequential overexpression patterns of T-helper cytokines during acute (cellular) rejection, and correlation of proinflammatory cytokine expression with chronic (ductopenic) rejection of human liver allografts: a study under cyclosporine, FK 506, and quadruple BT 563 immunosuppression. |
1995 |
Transplant. Proc. |
pmid:7533370
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Soldin SJ |
Receptor (immunophilin-binding) assay for immunosuppressive drugs. |
1995 |
Ther Drug Monit |
pmid:8588223
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Armstrong VW et al. |
Metabolic liver function and lipoprotein metabolism after orthotopic liver transplantation in patients on immunosuppressive therapy with FK 506 or cyclosporine. |
1995 |
Transplant. Proc. |
pmid:7533371
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Thomson AW et al. |
Mode of action of tacrolimus (FK506): molecular and cellular mechanisms. |
1995 |
Ther Drug Monit |
pmid:8588225
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Martinez OM et al. |
Molecular markers of Epstein-Barr virus infection in the circulation of transplant recipients. |
1995 |
Transplant. Proc. |
pmid:7533372
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Fung JJ and Starzl TE |
FK506 in solid organ transplantation. |
1995 |
Ther Drug Monit |
pmid:8588226
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Langrehr JM et al. |
Liver transplantation in hepatitis B surface antigen positive patients with postoperative long-term immunoprophylaxis. |
1995 |
Transplant. Proc. |
pmid:7533373
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Jusko WJ |
Analysis of tacrolimus (FK 506) in relation to therapeutic drug monitoring. |
1995 |
Ther Drug Monit |
pmid:8588227
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Vargas V et al. |
Alpha-interferon for acute hepatitis C in liver transplant patients. |
1995 |
Transplant. Proc. |
pmid:7533374
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McMaster P et al. |
Therapeutic drug monitoring of tacrolimus in clinical transplantation. |
1995 |
Ther Drug Monit |
pmid:8588228
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Barkholt LM et al. |
New criteria for diagnosing cytomegalovirus hepatitis in liver transplant patients. |
1995 |
Transplant. Proc. |
pmid:7533375
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Jusko WJ et al. |
Consensus document: therapeutic monitoring of tacrolimus (FK-506). |
1995 |
Ther Drug Monit |
pmid:8588229
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Teraoka S et al. |
Effect of rescue therapy using FK 506 on relapsing rejection after combined pancreas and kidney transplantation. |
1995 |
Transplant. Proc. |
pmid:7533381
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Lohse DL et al. |
Insights derived from the structures of the Ser/Thr phosphatases calcineurin and protein phosphatase 1. |
1995 |
Structure |
pmid:8590008
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Fay JW et al. |
FK 506-based immunosuppression for prevention of graft versus host disease after unrelated donor marrow transplantation. |
1995 |
Transplant. Proc. |
pmid:7533383
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Murase N et al. |
Bone marrow augmentation for heart, liver, and small bowel transplantation: prolongation of graft survival and incidence of graft-versus-host disease. |
1995 |
Transplant. Proc. |
pmid:7533386
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Zeevi A et al. |
Serial evaluation of immune profiles of simultaneous bone marrow and whole organ transplant recipients. |
1995 |
Transplant. Proc. |
pmid:7533388
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Funayama Y et al. |
Changes in cell adhesion molecules after small bowel transplantation in rats. |
1995 |
Transplant. Proc. |
pmid:7533426
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Laskow DA et al. |
Phase II FK 506 multicenter concentration control study: one-year follow-up. |
1995 |
Transplant. Proc. |
pmid:7533431
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Shapiro R et al. |
A prospective, randomized trial of FK 506/prednisone vs FK 506/azathioprine/prednisone in renal transplant patients. |
1995 |
Transplant. Proc. |
pmid:7533432
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Winkler M et al. |
Comparison of plasma vs whole blood as matrix for FK 506 drug level monitoring. |
1995 |
Transplant. Proc. |
pmid:7533433
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Sakamoto K et al. |
Sodium-losing nephropathy and distal tubular damage of transplant kidneys with FK506 administration. |
1995 |
Transplant. Proc. |
pmid:7533434
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Ochiai T et al. |
Phase III study of FK 506 in kidney transplantation. Japanese FK 506 Study Group. |
1995 |
Transplant. Proc. |
pmid:7533435
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Scantlebury VP et al. |
Renal transplantation under cyclosporine and FK 506 for hemolytic uremic syndrome. |
1995 |
Transplant. Proc. |
pmid:7533436
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Hanafusa T et al. |
Long-term impact of hepatitis virus infection on kidney transplant recipients and a pilot study of the effects of interferon alpha on chronic hepatitis C. |
1995 |
Transplant. Proc. |
pmid:7533440
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Bundick RV et al. |
The effect of cyclosporin A, FK506, and rapamycin on the murine chronic graft-versus-host response--an in vivo model of Th2-like activity. |
1995 |
Clin. Exp. Immunol. |
pmid:7533681
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Hirakata Y et al. |
Influence of various immunosuppressive agents on the occurrence of endogenous bacteraemia in mice. |
1995 |
J. Med. Microbiol. |
pmid:7533840
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Shaffer D et al. |
Normal pancreas allograft function following simultaneous pancreas kidney transplantation after rescue therapy with tacrolimus (FK506). |
1995 |
Transplantation |
pmid:7535958
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Bronster DJ et al. |
Demyelinating sensorimotor polyneuropathy after administration of FK506. |
1995 |
Transplantation |
pmid:7535959
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Sheppard KE |
Cyclosporin A and FK506 are potent activators of proopiomelanocortin-derived peptide secretion without affecting corticotrope glucocorticoid receptor function. |
1995 |
J. Neuroendocrinol. |
pmid:8748119
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Further metabolism of FK506 (tacrolimus). Identification and biological activities of the metabolites oxidized at multiple sites of FK506. |
1995 |
Drug Metab. Dispos. |
pmid:7536652
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Tumlin JA et al. |
Expression of calcineurin activity and alpha-subunit isoforms in specific segments of the rat nephron. |
1995 |
Am. J. Physiol. |
pmid:7485542
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Furukawa F et al. |
FK506: therapeutic effects on lupus dermatoses in autoimmune-prone MRL/Mp-lpr/lpr mice. |
1995 |
Arch. Dermatol. Res. |
pmid:7487142
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Miranker A and Karplus M |
An automated method for dynamic ligand design. |
1995 |
Proteins |
pmid:8749844
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Marumo T et al. |
Cyclosporin A inhibits nitric oxide synthase induction in vascular smooth muscle cells. |
1995 |
Hypertension |
pmid:7536714
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Lapa e Silva JR et al. |
Modulation of the bronchial inflammation in sensitized guinea-pigs by FK506, nedocromil sodium and dexamethasone. |
1995 |
Eur. Respir. J. |
pmid:7489798
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Schwaninger M et al. |
Involvement of the Ca(2+)-dependent phosphatase calcineurin in gene transcription that is stimulated by cAMP through cAMP response elements. |
1995 |
J. Biol. Chem. |
pmid:7536740
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Min Z and Jones NF |
Limb transplantation in rats: immunosuppression with FK-506. |
1995 |
J Hand Surg Am |
pmid:7536766
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Lyons WE et al. |
Neuronal regeneration enhances the expression of the immunophilin FKBP-12. |
1995 |
J. Neurosci. |
pmid:7536825
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Wortis HH et al. |
B-cell activation by crosslinking of surface IgM or ligation of CD40 involves alternative signal pathways and results in different B-cell phenotypes. |
1995 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:7536930
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Yamamoto S et al. |
Cross-species transplantation of photoreceptors with tacrolimus hydrate (FK506) treatment. |
1995 |
Jpn. J. Ophthalmol. |
pmid:8926639
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Asano K et al. |
Generation of effector T cells in Hymenolepis nana-infected, FK-506-treated BALB/c mice. |
1995 |
Immunol. Lett. |
pmid:7590919
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Lam E et al. |
A novel FK506 binding protein can mediate the immunosuppressive effects of FK506 and is associated with the cardiac ryanodine receptor. |
1995 |
J. Biol. Chem. |
pmid:7592869
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Kanda T et al. |
Synergistic effects of tacrolimus and human interferon-alpha A/D in murine viral myocarditis. |
1995 |
J. Pharmacol. Exp. Ther. |
pmid:7542339
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Jurim O et al. |
Living-donor liver transplantation at UCLA. |
1995 |
Am. J. Surg. |
pmid:7538267
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Canzanello VJ et al. |
Renal sodium handling with cyclosporin A and FK506 after orthotopic liver transplantation. |
1995 |
J. Am. Soc. Nephrol. |
pmid:7542491
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Inhibitory effect of cyclosporin A and FK506 on nitric oxide production by cultured macrophages. Evidence of a direct effect on nitric oxide synthase activity. |
1995 |
Immunology |
pmid:7538492
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Garrett-Engele P et al. |
Calcineurin, the Ca2+/calmodulin-dependent protein phosphatase, is essential in yeast mutants with cell integrity defects and in mutants that lack a functional vacuolar H(+)-ATPase. |
1995 |
Mol. Cell. Biol. |
pmid:7542741
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Skeen MJ and Ziegler HK |
Activation of gamma delta T cells for production of IFN-gamma is mediated by bacteria via macrophage-derived cytokines IL-1 and IL-12. |
1995 |
J. Immunol. |
pmid:7538532
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Baughman G et al. |
FKBP51, a novel T-cell-specific immunophilin capable of calcineurin inhibition. |
1995 |
Mol. Cell. Biol. |
pmid:7542743
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Columbo M et al. |
Human skin mast cells express functional beta 1 integrins that mediate adhesion to extracellular matrix proteins. |
1995 |
J. Immunol. |
pmid:7538541
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Pearlman DA and Connelly PR |
Determination of the differential effects of hydrogen bonding and water release on the binding of FK506 to native and Tyr82-->Phe82 FKBP-12 proteins using free energy simulations. |
1995 |
J. Mol. Biol. |
pmid:7538591
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Warty V et al. |
Tacrolimus analysis: a comparison of different methods and matrices. |
1995 |
Ther Drug Monit |
pmid:7542809
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Dumont FJ et al. |
Dominant mutations confer resistance to the immunosuppressant, rapamycin, in variants of a T cell lymphoma. |
1995 |
Cell. Immunol. |
pmid:7538911
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Theopold U et al. |
FKBP39, a Drosophila member of a family of proteins that bind the immunosuppressive drug FK506. |
1995 |
Gene |
pmid:7538962
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Sakamoto K et al. |
A new assay method for immunosuppressants with a tacrolimus (FK506)-like mode of action. |
1995 |
J. Antibiot. |
pmid:7544337
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Lee MJ et al. |
Combined inhibition effects of tacrolimus and methylprednisolone on in vitro human lymphocyte proliferation. |
1995 |
Immunopharmacol Immunotoxicol |
pmid:7544367
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Sauer P et al. |
In patients with orthotopic liver transplantation, serum markers of cholestasis are unreliable indicators of biliary secretion. |
1995 |
J. Hepatol. |
pmid:7544368
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Chang HY et al. |
Asymmetric retraction of growth cone filopodia following focal inactivation of calcineurin. |
1995 |
Nature |
pmid:7544441
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Reichenspurner H et al. |
First experience with FK 506 for treatment of chronic pulmonary rejection. |
1995 |
Transplant. Proc. |
pmid:7540775
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Murio JE et al. |
Compassionate use of FK 506 in liver transplantation. |
1995 |
Transplant. Proc. |
pmid:7544501
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Yumiba T et al. |
Immunosuppressive and diabetogenic effect of FK 506 on pancreatic islet xenotransplantation. |
1995 |
Transplant. Proc. |
pmid:7540780
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Llull R et al. |
Multilineage amplification of graft-vs-host disease-resistant chimerism following rat vascularized bone marrow allotransplantation. |
1995 |
Transplant. Proc. |
pmid:7544504
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Horne SM and Young KD |
Escherichia coli and other species of the Enterobacteriaceae encode a protein similar to the family of Mip-like FK506-binding proteins. |
1995 |
Arch. Microbiol. |
pmid:7540828
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Teutsch M et al. |
Induction of CD5 on B and T cells is suppressed by cyclosporin A, FK-520 and rapamycin. |
1995 |
Int. Immunol. |
pmid:7540861
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Hoshino H et al. |
Effects of FK506 on an experimental model of colitis in rats. |
1995 |
Aliment. Pharmacol. Ther. |
pmid:7544633
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Mori A et al. |
IL-5 production by CD4+ T cells of asthmatic patients is suppressed by glucocorticoids and the immunosuppressants FK506 and cyclosporin A. |
1995 |
Int. Immunol. |
pmid:7540862
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Firdaous I et al. |
HPLC-microparticle enzyme immunoassay specific for tacrolimus in whole blood of hepatic and renal transplant patients. |
1995 |
Clin. Chem. |
pmid:7544705
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Tashiro H et al. |
Monitoring for engraftment following rat orthotopic liver transplantation by in vitro amplification of Y-chromosome gene using polymerase chain reaction. |
1995 |
Cell Transplant |
pmid:7540919
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Ingels SC et al. |
Stability of FK506 (tacrolimus) in whole-blood specimens. |
1995 |
Clin. Chem. |
pmid:7544707
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Hikita N et al. |
Effects of topical FK506 on endotoxin-induced uveitis (EIU) in the Lewis rat. |
1995 |
Curr. Eye Res. |
pmid:7540967
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Cardenas ME et al. |
Targets of immunophilin-immunosuppressant complexes are distinct highly conserved regions of calcineurin A. |
1995 |
EMBO J. |
pmid:7540976
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Madsen KL et al. |
FK506 increases permeability in rat intestine by inhibiting mitochondrial function. |
1995 |
Gastroenterology |
pmid:7540994
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Yang WM et al. |
Cyclophilin A and FKBP12 interact with YY1 and alter its transcriptional activity. |
1995 |
J. Biol. Chem. |
pmid:7541038
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Platz KP et al. |
Toxicity versus rejection--or why conversions between cyclosporine A and FK506 were performed after liver transplantation. |
1995 |
Clin Transplant |
pmid:7549052
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Mueller AR et al. |
The optimal immunosuppressant after liver transplantation according to diagnosis: cyclosporine A or FK506? |
1995 |
Clin Transplant |
pmid:7549057
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Nagai H et al. |
Effect of some immunosuppressors on allergic bronchial inflammation and airway hyperresponsiveness in mice. |
1995 |
Int. Arch. Allergy Immunol. |
pmid:7549508
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Jung-Testas I et al. |
Cyclosporin A promotes nuclear transfer of a cytoplasmic progesterone receptor mutant. |
1995 |
C. R. Acad. Sci. III, Sci. Vie |
pmid:7583777
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Kissinger CR et al. |
Crystal structures of human calcineurin and the human FKBP12-FK506-calcineurin complex. |
1995 |
Nature |
pmid:8524402
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Lauerma AI |
Immunomodulation of contact dermatitis. |
1995 |
Curr. Probl. Dermatol. |
pmid:7587333
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Cardenas ME et al. |
Molecular mechanisms of immunosuppression by cyclosporine, FK506, and rapamycin. |
1995 |
Curr. Opin. Nephrol. Hypertens. |
pmid:8591053
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Wera S et al. |
Cyclosporin A, rapamycin and FK506 decrease prolactin release from rat pituitary cells in primary culture. |
1995 |
Endocr. Res. |
pmid:7588431
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Lake KD and Canafax DM |
Important interactions of drugs with immunosuppressive agents used in transplant recipients. |
1995 |
J. Antimicrob. Chemother. |
pmid:8601538
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Cameron AM et al. |
Calcineurin associated with the inositol 1,4,5-trisphosphate receptor-FKBP12 complex modulates Ca2+ flux. |
1995 |
Cell |
pmid:8521476
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Tamura K |
FK506: mechanism of immunosuppression and adverse-effects. |
1995 |
J Toxicol Sci |
pmid:8531246
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Mugiya S et al. |
Renal blood flow, fibrinolysis, and platelet aggregation following tacrolimus (FK 506) treatment in rats. |
1995 |
Thromb. Res. |
pmid:8533130
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