Uyeda M et al. |
Pentalenolactone I and hygromycin A, immunosuppressants produced by Streptomyces filipinensis and Streptomyces hygroscopicus. |
2001 |
Biosci. Biotechnol. Biochem. |
pmid:11440152
|
Kume K et al. |
Screening for a gene deletion mutant whose temperature sensitivity is suppressed by FK506 in budding yeast and its application for a positive screening for drugs inhibiting calcineurin. |
2015 |
Biosci. Biotechnol. Biochem. |
pmid:25614218
|
Funabashi H et al. |
Glucose oxidase assisted homogeneous electrochemical receptor binding assay for drug screening. |
2006 |
Biosens Bioelectron |
pmid:16169211
|
Tajdaran K et al. |
A novel polymeric drug delivery system for localized and sustained release of tacrolimus (FK506). |
2015 |
Biotechnol. Bioeng. |
pmid:25850693
|
Xia M et al. |
Enhanced FK506 production in Streptomyces tsukubaensis by rational feeding strategies based on comparative metabolic profiling analysis. |
2013 |
Biotechnol. Bioeng. |
pmid:23682004
|
Qi H et al. |
Integration of parallel C-labeling experiments and in silico pathway analysis for enhanced production of ascomycin. |
2017 |
Biotechnol. Bioeng. |
pmid:27869289
|
Fu LF et al. |
Improvement of FK506 production by synthetic biology approaches. |
2016 |
Biotechnol. Lett. |
pmid:27600954
|
Li X et al. |
Immunophilin FK506 loaded in chitosan guide promotes peripheral nerve regeneration. |
2010 |
Biotechnol. Lett. |
pmid:20443046
|
Gailliot FP et al. |
Fluidized bed adsorption for whole broth extraction. |
1990 Sep-Oct |
Biotechnol. Prog. |
pmid:1366874
|
Takaori K et al. |
A comparative study on immunosuppressive effects of cyclosporin A and FK 506 on peripheral blood lymphocytes in dogs. |
1992 |
Biotherapy |
pmid:1377926
|
Edey K et al. |
Topical tacrolimus in the management of lichen sclerosus. |
2006 |
BJOG |
pmid:17176285
|
Luesley DM and Downey GP |
Topical tacrolimus in the management of lichen sclerosus. |
2006 |
BJOG |
pmid:16827768
|
Lagoda G et al. |
FK506-binding protein localizations in human penile innervation. |
2008 |
BJU Int. |
pmid:18005210
|
Koreth J et al. |
Bortezomib, tacrolimus, and methotrexate for prophylaxis of graft-versus-host disease after reduced-intensity conditioning allogeneic stem cell transplantation from HLA-mismatched unrelated donors. |
2009 |
Blood |
pmid:19713456
|
Abu Zaid M et al. |
Plasma biomarkers of risk for death in a multicenter phase 3 trial with uniform transplant characteristics post-allogeneic HCT. |
2017 |
Blood |
pmid:27827824
|
Abdel-Azim H et al. |
Expansion of multipotent and lymphoid-committed human progenitors through intracellular dimerization of Mpl. |
2008 |
Blood |
pmid:18174381
|
Otto KG et al. |
Cell proliferation through forced engagement of c-Kit and Flt-3. |
2001 |
Blood |
pmid:11369667
|
Choi SW et al. |
Vorinostat plus tacrolimus/methotrexate to prevent GVHD after myeloablative conditioning, unrelated donor HCT. |
2017 |
Blood |
pmid:28784598
|
Yoshikawa H et al. |
Fc gammaRIII-mediated regulation of hematopoiesis in murine bone marrow cells by interleukin-3 and CD95 (Fas/Apo-1). |
1997 |
Blood |
pmid:9292524
|
Jiang H et al. |
Effects of transient immunosuppression on adenoassociated, virus-mediated, liver-directed gene transfer in rhesus macaques and implications for human gene therapy. |
2006 |
Blood |
pmid:16868252
|
Cutler C et al. |
Extended follow-up of methotrexate-free immunosuppression using sirolimus and tacrolimus in related and unrelated donor peripheral blood stem cell transplantation. |
2007 |
Blood |
pmid:17138818
|
Pulsipher MA et al. |
The addition of sirolimus to tacrolimus/methotrexate GVHD prophylaxis in children with ALL: a phase 3 Children's Oncology Group/Pediatric Blood and Marrow Transplant Consortium trial. |
2014 |
Blood |
pmid:24497539
|
Khouri IF et al. |
Nonablative allogeneic hematopoietic transplantation as adoptive immunotherapy for indolent lymphoma: low incidence of toxicity, acute graft-versus-host disease, and treatment-related mortality. |
2001 |
Blood |
pmid:11739162
|
Kharfan-Dabaja MA et al. |
Thrombotic microangiopathy after GVHD prophylaxis with tacrolimus/sirolimus: a call for use of consensus definition in reporting. |
2010 |
Blood |
pmid:20508174
|
Hirao A et al. |
Effects of immunosuppressants, FK506, deoxyspergualin, and cyclosporine A on immature human hematopoiesis. |
1993 |
Blood |
pmid:7680241
|
Kriss M et al. |
Haploidentical hematopoietic stem cell transplantation for graft-versus-host disease after liver transplantation. |
2011 |
Blood |
pmid:21940833
|
Ricciardelli I et al. |
Towards gene therapy for EBV-associated posttransplant lymphoma with genetically modified EBV-specific cytotoxic T cells. |
2014 |
Blood |
pmid:25185261
|
Fay JW et al. |
FK506 (Tacrolimus) monotherapy for prevention of graft-versus-host disease after histocompatible sibling allogenic bone marrow transplantation. |
1996 |
Blood |
pmid:8605372
|
Nakao A et al. |
Simultaneous bone marrow and intestine transplantation promotes marrow-derived hematopoietic stem cell engraftment and chimerism. |
2006 |
Blood |
pmid:16638929
|
Uchida N et al. |
Myocardial ischemia following allogeneic bone marrow transplantation: possible implication of tacrolimus overdose. |
2000 |
Blood |
pmid:10939803
|
Zoeteweij JP et al. |
Targeted inhibition of calcineurin signaling blocks calcium-dependent reactivation of Kaposi sarcoma-associated herpesvirus. |
2001 |
Blood |
pmid:11290600
|
Fortin JF et al. |
Regulation of nuclear factor of activated T cells by phosphotyrosyl-specific phosphatase activity: a positive effect on HIV-1 long terminal repeat-driven transcription and a possible implication of SHP-1. |
2001 |
Blood |
pmid:11290602
|
Peters D et al. |
Potentiation of CD3-induced expression of the linker for activation of T cells (LAT) by the calcineurin inhibitors cyclosporin A and FK506. |
2000 |
Blood |
pmid:10779414
|
Mehta BA et al. |
Two pathways of exocytosis of cytoplasmic granule contents and target cell killing by cytokine-induced CD3+ CD56+ killer cells. |
1995 |
Blood |
pmid:7579455
|
Hemenway C |
FK506 in bone marrow transplantation. |
1995 |
Blood |
pmid:7579473
|
Nash RA et al. |
Phase 3 study comparing methotrexate and tacrolimus with methotrexate and cyclosporine for prophylaxis of acute graft-versus-host disease after marrow transplantation from unrelated donors. |
2000 |
Blood |
pmid:10979948
|
Cutler C et al. |
Tacrolimus/sirolimus vs tacrolimus/methotrexate as GVHD prophylaxis after matched, related donor allogeneic HCT. |
2014 |
Blood |
pmid:24982504
|
Lee YR et al. |
Cyclosporin A and tacrolimus, but not rapamycin, inhibit MHC-restricted antigen presentation pathways in dendritic cells. |
2005 |
Blood |
pmid:15657176
|
Rodriguez R et al. |
A phase II pilot study of tacrolimus/sirolimus GVHD prophylaxis for sibling donor hematopoietic stem cell transplantation using 3 conditioning regimens. |
2010 |
Blood |
pmid:19965688
|
Mouzaki A and Rungger D |
Properties of transcription factors regulating interleukin-2 gene transcription through the NFAT binding site in untreated or drug-treated naive and memory T-helper cells. |
1994 |
Blood |
pmid:7522636
|
Brewin J et al. |
Generation of EBV-specific cytotoxic T cells that are resistant to calcineurin inhibitors for the treatment of posttransplantation lymphoproliferative disease. |
2009 |
Blood |
pmid:19770360
|
Cunningham EB |
An inositolphosphate-binding immunophilin, IPBP12. |
1999 |
Blood |
pmid:10515881
|
Joneja U and Uppal G |
Pseudo-Pelger-Huët anomaly in a patient on tacrolimus. |
2015 |
Blood |
pmid:26371350
|
Arceci RJ et al. |
Immunosuppressants FK506 and rapamycin function as reversal agents of the multidrug resistance phenotype. |
1992 |
Blood |
pmid:1381629
|
Adachi M et al. |
Interleukin-2 (IL-2) upregulates BAG-1 gene expression through serine-rich region within IL-2 receptor beta c chain. |
1996 |
Blood |
pmid:8943845
|
Hooijberg E et al. |
NFAT-controlled expression of GFP permits visualization and isolation of antigen-stimulated primary human T cells. |
2000 |
Blood |
pmid:10887106
|
Przepiorka D et al. |
Tacrolimus and minidose methotrexate for prevention of acute graft-versus-host disease after matched unrelated donor marrow transplantation. |
1996 |
Blood |
pmid:8943876
|
Nash RA et al. |
Tacrolimus (FK506) alone or in combination with methotrexate or methylprednisolone for the prevention of acute graft-versus-host disease after marrow transplantation from HLA-matched siblings: a single-center study. |
1995 |
Blood |
pmid:7540071
|
Taylor PA et al. |
Combined effects of calcineurin inhibitors or sirolimus with anti-CD40L mAb on alloengraftment under nonmyeloablative conditions. |
2002 |
Blood |
pmid:12384443
|
Hackstein H et al. |
Rapamycin inhibits macropinocytosis and mannose receptor-mediated endocytosis by bone marrow-derived dendritic cells. |
2002 |
Blood |
pmid:12130531
|
Ratanatharathorn V et al. |
Phase III study comparing methotrexate and tacrolimus (prograf, FK506) with methotrexate and cyclosporine for graft-versus-host disease prophylaxis after HLA-identical sibling bone marrow transplantation. |
1998 |
Blood |
pmid:9746768
|
Nash RA et al. |
FK506 in combination with methotrexate for the prevention of graft-versus-host disease after marrow transplantation from matched unrelated donors. |
1996 |
Blood |
pmid:8896434
|
Aruch DB and Renteria A |
Simultaneous PRES and TMA secondary to tacrolimus after allogeneic bone marrow transplant. |
2015 |
Blood |
pmid:26287041
|
Neff T et al. |
Pharmacologically regulated in vivo selection in a large animal. |
2002 |
Blood |
pmid:12200362
|
Parrow NL and Fleming RE |
Releasing the FKBP12 brake on hepcidin. |
2017 |
Blood |
pmid:29122771
|
Antin JH et al. |
Sirolimus, tacrolimus, and low-dose methotrexate for graft-versus-host disease prophylaxis in mismatched related donor or unrelated donor transplantation. |
2003 |
Blood |
pmid:12730113
|
De Angelis B et al. |
Generation of Epstein-Barr virus-specific cytotoxic T lymphocytes resistant to the immunosuppressive drug tacrolimus (FK506). |
2009 |
Blood |
pmid:19759356
|
Jin L et al. |
Stimulating cell proliferation through the pharmacologic activation of c-kit. |
1998 |
Blood |
pmid:9446649
|
Colucci S et al. |
The immunophilin FKBP12 inhibits hepcidin expression by binding the BMP type I receptor ALK2 in hepatocytes. |
2017 |
Blood |
pmid:28864813
|
Zhu X et al. |
Pilot study using tacrolimus rather than cyclosporine plus antithymocyte globulin as an immunosuppressive therapy regimen option for severe aplastic anemia in adults. |
2014 |
Blood Cells Mol. Dis. |
pmid:24931461
|
de Cal M et al. |
Oxidative stress and 'monocyte reprogramming' after kidney transplant: a longitudinal study. |
2008 |
Blood Purif. |
pmid:18182807
|
Arai S and Vogelsang GB |
Management of graft-versus-host disease. |
2000 |
Blood Rev. |
pmid:11124107
|
Pardi C and Oltean M |
An unusual case of red blood cell immunisation following liver transplantation. |
2015 |
Blood Transfus |
pmid:26057497
|
Zhang L et al. |
Characterization of calcineurin from Cryptococcus humicola and the application of calcineurin in aluminum tolerance. |
2017 |
BMC Biotechnol. |
pmid:28356086
|
Becker JC et al. |
The carcinogenic potential of tacrolimus ointment beyond immune suppression: a hypothesis creating case report. |
2006 |
BMC Cancer |
pmid:16405733
|
Jia N et al. |
Collapsing focal segmental glomerulosclerosis following long-term treatment with oral ibandronate: case report and review of literature. |
2015 |
BMC Cancer |
pmid:26197890
|
Buchwald A et al. |
Validation of an LC-MS/MS method to determine five immunosuppressants with deuterated internal standards including MPA. |
2012 |
BMC Clin Pharmacol |
pmid:22236286
|
Boms S et al. |
Pimecrolimus 1% cream for anogenital lichen sclerosus in childhood. |
2004 |
BMC Dermatol. |
pmid:15485581
|
Hiraoka S et al. |
The earliest trough concentration predicts the dose of tacrolimus required for remission induction therapy in ulcerative colitis patients. |
2015 |
BMC Gastroenterol |
pmid:25925267
|
Takazono T et al. |
Paradoxical response to disseminated non-tuberculosis mycobacteriosis treatment in a patient receiving tumor necrosis factor-α inhibitor: a case report. |
2014 |
BMC Infect. Dis. |
pmid:24576098
|
GoranoviÄ D et al. |
FK506 biosynthesis is regulated by two positive regulatory elements in Streptomyces tsukubaensis. |
2012 |
BMC Microbiol. |
pmid:23083511
|
Jia W et al. |
The calcineruin inhibitor cyclosporine a synergistically enhances the susceptibility of Candida albicans biofilms to fluconazole by multiple mechanisms. |
2016 |
BMC Microbiol. |
pmid:27316338
|
Hurtgen BJ et al. |
Impairment of early fracture healing by skeletal muscle trauma is restored by FK506. |
2017 |
BMC Musculoskelet Disord |
pmid:28606129
|
Shimojima Y et al. |
Coadministration of tacrolimus with corticosteroid accelerates recovery in refractory patients with polymyositis/ dermatomyositis: a retrospective study. |
2012 |
BMC Musculoskelet Disord |
pmid:23173570
|
Birdwell KA et al. |
Assessment of arterial stiffness using pulse wave velocity in tacrolimus users the first year post kidney transplantation: a prospective cohort study. |
2015 |
BMC Nephrol |
pmid:26133166
|
Chegounchi M et al. |
Progressive neurological disease induced by tacrolimus in a renal transplant recipient: case presentation. |
2006 |
BMC Nephrol |
pmid:16573841
|
Luo L et al. |
Mycophenolate mofetil and FK506 have different effects on kidney allograft fibrosis in rats that underwent chronic allograft nephropathy. |
2012 |
BMC Nephrol |
pmid:22747784
|
Liu S et al. |
Comparison of tripterygium wilfordii multiglycosides and tacrolimus in the treatment of idiopathic membranous nephropathy: a prospective cohort study. |
2015 |
BMC Nephrol |
pmid:26637482
|
Yu H et al. |
Risk factors for new-onset diabetes mellitus after living donor kidney transplantation in Korea - a retrospective single center study. |
2016 |
BMC Nephrol |
pmid:27473469
|
Xie X et al. |
mTOR inhibitor versus mycophenolic acid as the primary immunosuppression regime combined with calcineurin inhibitor for kidney transplant recipients: a meta-analysis. |
2015 |
BMC Nephrol |
pmid:26126806
|
Qin HZ et al. |
Evaluating tacrolimus treatment in idiopathic membranous nephropathy in a cohort of 408 patients. |
2017 |
BMC Nephrol |
pmid:28056860
|
Younas N et al. |
HMG-CoA reductase inhibitors in kidney transplant recipients receiving tacrolimus: statins not associated with improved patient or graft survival. |
2010 |
BMC Nephrol |
pmid:20359353
|
Wlodarczyk Z et al. |
A multicenter, randomized, double-blind study comparing different FK778 doses (manitimus) with tacrolimus and steroids vs. MMF with tacrolimus and steroids in renal transplantation. |
2012 |
BMC Nephrol |
pmid:22835011
|
Gmitterová K et al. |
Tacrolimus-induced parkinsonism in a patient after liver transplantation - case report. |
2018 |
BMC Neurol |
pmid:29678162
|
Madian AG et al. |
Case report: Inability to achieve a therapeutic dose of tacrolimus in a pediatric allogeneic stem cell transplant patient after generic substitution. |
2014 |
BMC Pharmacol Toxicol |
pmid:25472557
|
Neye H and Verspohl EJ |
The FK506 binding protein 13 kDa (FKBP13) interacts with the C-chain of complement C1q. |
2004 |
BMC Pharmacol. |
pmid:15353007
|
Dury S et al. |
Bronchiectasis diagnosed after renal transplantation: a retrospective multicenter study. |
2015 |
BMC Pulm Med |
pmid:26545860
|
Kato M et al. |
Pneumocystis pneumonia induced by treatment with low-dose tacrolimus and methylprednisolone in a patient with rheumatoid arthritis: a case report. |
2013 |
BMC Res Notes |
pmid:24289285
|
Hadjipanagi D et al. |
Genetic polymorphisms in warfarin and tacrolimus-related genes VKORC1, CYP2C9 and CYP3A5 in the Greek-Cypriot population. |
2014 |
BMC Res Notes |
pmid:24593903
|
Yamada K et al. |
Correlation between disease activity and serum ferritin in clinically amyopathic dermatomyositis with rapidly-progressive interstitial lung disease: a case report. |
2018 |
BMC Res Notes |
pmid:29338781
|
Rice SA et al. |
Topical tacrolimus 0.1% ointment for treatment of cutaneous Crohn's Disease. |
2013 |
BMC Res Notes |
pmid:23331739
|
Briffa N and Morris RE |
Immunosuppressive drugs after lung transplantation. |
1998 |
BMJ |
pmid:9529396
|
Morris-Stiff G et al. |
Immunosuppression in renal transplantation. Meta-analysis should not have included one of the studies. |
1999 |
BMJ |
pmid:10531121
|
Knoll GA and Bell RC |
Tacrolimus versus cyclosporin for immunosuppression in renal transplantation: meta-analysis of randomised trials. |
1999 |
BMJ |
pmid:10213717
|
Daunton A et al. |
A cutaneous presentation of a common condition. |
2015 |
BMJ |
pmid:26681202
|
Williams H |
New treatments for atopic dermatitis. |
2002 |
BMJ |
pmid:12089073
|
Lapsley P |
Itching for a solution. |
2005 |
BMJ |
pmid:15731120
|
Ashcroft DM et al. |
Efficacy and tolerability of topical pimecrolimus and tacrolimus in the treatment of atopic dermatitis: meta-analysis of randomised controlled trials. |
2005 |
BMJ |
pmid:15731121
|
Brousse N and Goulet O |
Small bowel transplantation. |
1996 |
BMJ |
pmid:8611766
|
Allen BR and Luger TA |
Risk: benefit ratio is important in treating atopic dermatitis. |
2002 |
BMJ |
pmid:12399360
|