Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with tacrolimus
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Kamanamool N et al. | Comparison of disease activity between tacrolimus and mycophenolate mofetil in lupus nephritis: a randomized controlled trial. | 2018 | Lupus | pmid:29105558 |
Kim JP et al. | The effect of full dose composite tissue allotransplantation immunosuppression on allograft motor nerve regeneration in a rat sciatic nerve model. | 2018 | Microsurgery | pmid:28792625 |
Min S et al. | A randomized clinical trial of age and genotype-guided tacrolimus dosing after pediatric solid organ transplantation. | 2018 | Pediatr Transplant | pmid:30178515 |
La Maestra S et al. | Brain microglia activation induced by intracranial administration of oligonucleotides and its pharmacological modulation. | 2018 | Drug Deliv Transl Res | pmid:29869293 |
Moura Neto A et al. | Frequency of Thyroid Dysfunction in Patients With Diabetes Mellitus Before and After Liver Transplantation. | 2018 | Transplant. Proc. | pmid:29661439 |
Efe C et al. | Tacrolimus and Mycophenolate Mofetil as Second-Line Therapies for Pediatric Patients with Autoimmune Hepatitis. | 2018 | Dig. Dis. Sci. | pmid:29569003 |
Bittersohl H et al. | A simple and highly sensitive on-line column extraction liquid chromatography-tandem mass spectrometry method for the determination of protein-unbound tacrolimus in human plasma samples. | 2018 | J Chromatogr A | pmid:29544893 |
Ghadimi M et al. | Tacrolimus interaction with oral oestrogen in kidney transplant recipients: A case-control study. | 2018 | J Clin Pharm Ther | pmid:29492991 |
Li X et al. | Association of the PPARγ/PI3K/Akt pathway with the cardioprotective effects of tacrolimus in myocardial ischemic/reperfusion injury. | 2018 | Mol Med Rep | pmid:29488613 |
Li YM et al. | Soluble Tim-3 and Gal-9 are associated with renal allograft dysfunction in kidney transplant recipients: A cross-sectional study. | 2018 | Int. Immunopharmacol. | pmid:29310109 |