tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (2)
- Am. J. Physiol. Renal Physiol. (1)
- Drug Metab. Dispos. (1)
- Others (1)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Breuer K et al. | Safety and efficacy of topical calcineurin inhibitors in the treatment of childhood atopic dermatitis. | 2005 | Am J Clin Dermatol | pmid:15799678 |
| Gupta AK and Versteeg SG | Topical Treatment of Facial Seborrheic Dermatitis: A Systematic Review. | 2017 | Am J Clin Dermatol | pmid:27804089 |
| Kalavala M and Dohil MA | Calcineurin inhibitors in pediatric atopic dermatitis: a review of current evidence. | 2011 | Am J Clin Dermatol | pmid:21067248 |
| Yang LP and Curran MP | Spotlight on topical pimecrolimus in pediatric atopic dermatitis. | 2010 | Am J Clin Dermatol | pmid:20509720 |
| Cheer SM and Plosker GL | Tacrolimus ointment. A review of its therapeutic potential as a topical therapy in atopic dermatitis. | 2001 | Am J Clin Dermatol | pmid:11770393 |
| Patel TS et al. | Cancer concerns with topical immunomodulators in atopic dermatitis: overview of data and recommendations to clinicians. | 2007 | Am J Clin Dermatol | pmid:17645374 |
| Mertens JS et al. | Morphea and Eosinophilic Fasciitis: An Update. | 2017 | Am J Clin Dermatol | pmid:28303481 |
| Frankel HC and Qureshi AA | Comparative effectiveness of topical calcineurin inhibitors in adult patients with atopic dermatitis. | 2012 | Am J Clin Dermatol | pmid:22263704 |
| Iskedjian M et al. | Topical calcineurin inhibitors in the treatment of atopic dermatitis: a meta-analysis of current evidence. | 2004 | Am J Clin Dermatol | pmid:15301573 |
| Kroft EB et al. | Efficacy of topical tacrolimus 0.1% in active plaque morphea: randomized, double-blind, emollient-controlled pilot study. | 2009 | Am J Clin Dermatol | pmid:19354332 |
| Tjioe M et al. | Topical macrolide immunomodulators: a role in the treatment of vitiligo? | 2006 | Am J Clin Dermatol | pmid:16489839 |
| Wellington K and Noble S | Pimecrolimus: a review of its use in atopic dermatitis. | 2004 | Am J Clin Dermatol | pmid:15663345 |
| Cook BA and Warshaw EM | Role of topical calcineurin inhibitors in the treatment of seborrheic dermatitis: a review of pathophysiology, safety, and efficacy. | 2009 | Am J Clin Dermatol | pmid:19222250 |
| Ingram JR et al. | Impact of topical calcineurin inhibitors on quality of life in patients with atopic dermatitis. | 2009 | Am J Clin Dermatol | pmid:19489656 |
| Reitamo S et al. | Topical noncorticosteroid immunomodulation in the treatment of atopic dermatitis. | 2002 | Am J Clin Dermatol | pmid:12113647 |
| Wellington K and Jarvis B | Spotlight on topical pimecrolimus in atopic dermatitis. | 2002 | Am J Clin Dermatol | pmid:12113651 |
| Lübbe J et al. | Safety, efficacy, and dosage of 1% pimecrolimus cream for the treatment of atopic dermatitis in daily practice. | 2006 | Am J Clin Dermatol | pmid:16605292 |
| Ellis CN et al. | Cost effectiveness of management of mild-to-moderate atopic dermatitis with 1% pimecrolimus cream in children and adolescents 2-17 years of age. | 2006 | Am J Clin Dermatol | pmid:16605293 |
| Wollina U | The role of topical calcineurin inhibitors for skin diseases other than atopic dermatitis. | 2007 | Am J Clin Dermatol | pmid:17492844 |
| Kasper RC et al. | Anetoderma arising in cutaneous B-cell lymphoproliferative disease. | 2001 | Am J Dermatopathol | pmid:11285407 |
| Roche, FDA announce new drug-interaction warnings for mibefradil. | 1998 | Am J Health Syst Pharm | pmid:9492249 | |
| Ku YM et al. | Compatibility of tacrolimus injection with cimetidine hydrochloride injection in 0.9% sodium chloride injection. | 1995 | Am J Health Syst Pharm | pmid:8528874 |
| Greanya ED et al. | Pharmacokinetics of tacrolimus and mycophenolate mofetil in renal transplant recipients on a corticosteroid-free regimen. | 2012 | Am J Health Syst Pharm | pmid:22215359 |
| Heavner MS et al. | Clinical outcomes associated with conversion from brand-name to generic tacrolimus in hospitalized kidney transplant recipients. | 2013 | Am J Health Syst Pharm | pmid:23943182 |
| Curtin BF et al. | Unusually late-onset mycophenolate mofetil-related colitis. | 2014 | Am J Health Syst Pharm | pmid:25320135 |
| Bonhomme-Faivre L et al. | Effect of the ABCB1 3435C>T polymorphism on tacrolimus concentrations and dosage requirements in liver transplant recipients. | 2009 | Am J Health Syst Pharm | pmid:19729569 |
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| Lee B et al. | Appropriate timing of tacrolimus concentration measurements in the emergency department. | 2016 | Am J Health Syst Pharm | pmid:27543574 |
| Jacobson PA et al. | Stability of tacrolimus in an extemporaneously compounded oral liquid. | 1997 | Am J Health Syst Pharm | pmid:9117806 |
| Utecht KN et al. | Effects of genetic polymorphisms on the pharmacokinetics of calcineurin inhibitors. | 2006 | Am J Health Syst Pharm | pmid:17106006 |
| Kelly PA et al. | Tacrolimus: a new immunosuppressive agent. | 1995 | Am J Health Syst Pharm | pmid:7552894 |
| MacDonald AS and Sketris IS | Tacrolimus in transplantation. | 1995 | Am J Health Syst Pharm | pmid:7552906 |
| Johnson CE et al. | Stability of tacrolimus with morphine sulfate, hydromorphone hydrochloride, and ceftazidime during simulated intravenous coadministration. | 1999 | Am J Health Syst Pharm | pmid:10030533 |
| Pennington CA and Park JM | Sublingual tacrolimus as an alternative to oral administration for solid organ transplant recipients. | 2015 | Am J Health Syst Pharm | pmid:25631834 |
| Tsapepas DS et al. | Managing the atazanavir-tacrolimus drug interaction in a renal transplant recipient. | 2011 | Am J Health Syst Pharm | pmid:21200061 |
| Myers AL et al. | Stability of tacrolimus injection diluted in 0.9% sodium chloride injection and stored in Excel bags. | 2016 | Am J Health Syst Pharm | pmid:27919876 |
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| Taormina D et al. | Stability and sorption of FK 506 in 5% dextrose injection and 0.9% sodium chloride injection in glass, polyvinyl chloride, and polyolefin containers. | 1992 | Am J Hosp Pharm | pmid:1373936 |
| Min DI et al. | Visual compatibility of tacrolimus with commonly used drugs during simulated Y-site injection. | 1992 | Am J Hosp Pharm | pmid:1282779 |
| Tacrolimus introduced for use in liver transplantation. | 1994 | Am J Hosp Pharm | pmid:7524317 | |
| Przepiorka D et al. | Blood tacrolimus concentration unchanged by plasmapheresis. | 1994 | Am J Hosp Pharm | pmid:7524318 |
| Matsunami H et al. | New technique for measuring tacrolimus concentrations in blood. | 1994 | Am J Hosp Pharm | pmid:7510929 |
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| Yang GS et al. | Intratympanic immunosuppressives for prevention of immune-mediated sensorineural hearing loss. | 2000 | Am J Otol | pmid:10912694 |
| Tulaci KG et al. | The effect of tacrolimus on facial nerve injury: Histopathological findings in a rabbit model. | Am J Otolaryngol | pmid:27465503 | |
| Knott PD et al. | Induction with T-cell receptor antibody leads to long-term laryngeal allograft function. | 2008 Nov-Dec | Am J Otolaryngol | pmid:19144301 |
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| Lee J et al. | Inpatient rehabilitation challenges in a quadrimembral amputee after bilateral hand transplantation. | 2011 | Am J Phys Med Rehabil | pmid:21765280 |
| Reams BD and Palmer SM | Sublingual tacrolimus for immunosuppression in lung transplantation: a potentially important therapeutic option in cystic fibrosis. | 2002 | Am J Respir Med | pmid:14720063 |