Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with tacrolimus
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Shin TH et al. | Formulation and in vivo pharmacokinetic evaluation of ethyl cellulose-coated sustained release multiple-unit system of tacrolimus. | 2018 | Int. J. Biol. Macromol. | pmid:29277422 |
Moriguchi S et al. | Reduced expression of Na/Ca exchangers is associated with cognitive deficits seen in Alzheimer's disease model mice. | 2018 | Neuropharmacology | pmid:29274751 |
Karagun BS et al. | Eye Movement Disorders Following Allogeneic Bone Marrow Transplantation on FK506 (Tacrolimus) and Ganciclovir. | 2018 | J. Pediatr. Hematol. Oncol. | pmid:28731920 |
Komura Y et al. | Economic assessment of actual prescription of drugs for treatment of atopic dermatitis: Differences between dermatology and pediatrics in large-scale receipt data. | 2018 | J. Dermatol. | pmid:29168213 |
Akamine Y et al. | A comparison of the effects of CYP3A5 polymorphism on tacrolimus blood concentrations measured by 4 immunoassay methods in renal transplant patients. | 2018 | J Clin Pharm Ther | pmid:28891077 |
Velioglu A et al. | Late Pulmonary Toxicity Associated With Everolimus in a Renal Transplant Patient and Review of the Literature. | 2018 | Exp Clin Transplant | pmid:27001620 |
Pflugrad H et al. | Longterm calcineurin inhibitor therapy and brain function in patients after liver transplantation. | 2018 | Liver Transpl. | pmid:29156491 |
Liu YJ et al. | Pooled analysis of the comparative efficacy between tacrolimus and infliximab for ulcerative colitis. | 2018 | Medicine (Baltimore) | pmid:30095612 |
Garaix F et al. | Tacrolimus Granules for Oral Suspension as Post-Transplant Immunosuppression in Routine Medical Practice in France: The OPTIMOD Study. | 2018 | Ann. Transplant. | pmid:30093607 |
Wang DD et al. | Population pharmacokinetics of tacrolimus in paediatric systemic lupus erythematosus based on real-world study. | 2018 | J Clin Pharm Ther | pmid:29766530 |
Rigo-Bonnin R et al. | Different top-down approaches to estimate measurement uncertainty of whole blood tacrolimus mass concentration values. | 2018 | Clin. Biochem. | pmid:29750938 |
Strohbehn GW et al. | Large-Scale Variability of Inpatient Tacrolimus Therapeutic Drug Monitoring at an Academic Transplant Center: A Retrospective Study. | 2018 | Ther Drug Monit | pmid:29750738 |
Nakagita K et al. | Effect of fluconazole on the pharmacokinetics of everolimus and tacrolimus in a heart transplant recipient: Case report. | 2018 | Int J Clin Pharmacol Ther | pmid:29648533 |
Kaya Z et al. | Tacrolimus-Induced Autoimmune Hemolytic Anemia in a Previously Reported Child With History of Thrombocytopenia Following Liver Transplant. | 2018 | Exp Clin Transplant | pmid:29633932 |
Nanmoku K et al. | Steroid Withdrawal Using Everolimus in ABO-Incompatible Kidney Transplant Recipients With Post-Transplant Diabetes Mellitus. | 2018 | Transplant. Proc. | pmid:29631750 |
Takeuchi K et al. | Comparison of Safety and Efficacy of Tacrolimus versus Infliximab for Active Ulcerative Colitis. | 2018 | Dig Dis | pmid:29050007 |
Mashiah J et al. | Topical pimecrolimus for paediatric cutaneous mastocytosis. | 2018 | Clin. Exp. Dermatol. | pmid:29460435 |
Chen ZH et al. | Adenovirus-mediated OX40Ig gene transfer induces long-term survival of orthotopic liver allograft in rats. | 2018 | Transpl. Immunol. | pmid:29454984 |
Yang MY et al. | High rates of secondary non-adherence causes decreased efficacy of 0.1% topical tacrolimus in adult eczema patients: results from a multicenter clinical trial. | 2018 | J Dermatolog Treat | pmid:28670943 |
Dheer D et al. | Tacrolimus: An updated review on delivering strategies for multifarious diseases. | 2018 | Eur J Pharm Sci | pmid:29277665 |