Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with tacrolimus
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Lee JH et al. | Withdrawal of immunosuppression in pediatric liver transplant recipients in Korea. | 2009 | Yonsei Med. J. | pmid:20046418 |
Schwarz A | [Drug-induced kidney damage]. | 1996 | Z Arztl Fortbild (Jena) | pmid:8779233 |
Ocran KW et al. | Tacrolimus toxicity due to drug interaction with mibefradil in a patient after liver transplantation. | 1999 | Z Gastroenterol | pmid:10549098 |
Müller MK et al. | [Pathophysiologic concepts and protective possibilities in experimental pancreatic lesions]. | 1993 | Z Gastroenterol | pmid:7504856 |
Petrides AS | [Do immunosuppressive agents really impair glucose tolerance in liver transplant patients?]. | 1995 | Z Gastroenterol | pmid:7571761 |
Arnold JC and Theilmann L | [Comparison between tacrolimus (FK 506) and cyclosporin in immunosuppressive therapy after liver transplantation]. | 1995 | Z Gastroenterol | pmid:7502559 |
Buechter M et al. | Tacrolimus as a reasonable alternative in a patient with steroid-dependent and thiopurine-refractory autoimmune pancreatitis with IgG4-associated cholangitis. | 2014 | Z Gastroenterol | pmid:24905108 |
Kanzler S et al. | Complete reversal of FK 506 induced diabetes in a liver transplant recipient by change of immunosuppression to cyclosporine A. | 1996 | Z Gastroenterol | pmid:8659188 |
Scheller B et al. | Comparative study of tacrolimus and paclitaxel stent coating in the porcine coronary model. | 2005 | Z Kardiol | pmid:15997345 |
König A et al. | Intravascular ultrasound for assessment of coronary allograft vasculopathy. | 2000 | Z Kardiol | pmid:11151792 |