tacrolimus

Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.

Cross Reference

Introduction

To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with tacrolimus?

tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with tacrolimus

MeSH term MeSH ID Detail
Hypersensitivity D006967 22 associated lipids
Hyperglycemia D006943 21 associated lipids
Anemia D000740 21 associated lipids
Bacterial Infections D001424 21 associated lipids
Vomiting D014839 21 associated lipids
Brain Edema D001929 20 associated lipids
Heart Defects, Congenital D006330 20 associated lipids
Dermatitis, Allergic Contact D017449 20 associated lipids
Translocation, Genetic D014178 20 associated lipids
Drug Hypersensitivity D004342 20 associated lipids
HIV Infections D015658 20 associated lipids
Ataxia D001259 20 associated lipids
Gastrointestinal Diseases D005767 20 associated lipids
Parkinsonian Disorders D020734 20 associated lipids
Nephritis D009393 19 associated lipids
Hypothermia D007035 19 associated lipids
Erectile Dysfunction D007172 19 associated lipids
Dermatitis, Atopic D003876 19 associated lipids
Peptic Ulcer D010437 19 associated lipids
Pregnancy Complications D011248 19 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with tacrolimus

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with tacrolimus?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with tacrolimus?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with tacrolimus?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with tacrolimus?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with tacrolimus?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with tacrolimus

Download all related citations
Per page 10 20 50 100 | Total 15051
Authors Title Published Journal PubMed Link
Schwarz C et al. Rescue therapy with tacrolimus and mycophenolate mofetil does not prevent deterioration of graft function in C4d-positive chronic allograft nephropathy. 2006 Wien. Klin. Wochenschr. pmid:16865644
Sperr WR et al. [Effector cells in allergy: biological principles and new pharmacologic concepts]. 1993 Wien. Klin. Wochenschr. pmid:7508662
Haas M et al. Hypothyroidism as a cause of tacrolimus intoxication and acute renal failure: a case report. 2000 Wien. Klin. Wochenschr. pmid:11144010
Zong YP et al. Effects of CYP3A5 polymorphisms on tacrolimus pharmacokinetics in pediatric kidney transplantation: a systematic review and meta-analysis of observational studies. 2017 World J Pediatr pmid:28540692
Yang EM et al. Tacrolimus for children with refractory nephrotic syndrome: a one-year prospective, multicenter, and open-label study of Tacrobell®, a generic formula. 2016 World J Pediatr pmid:26684309
Kallash M and Aviles D Efficacy of tacrolimus in the treatment of children with focal segmental glomerulosclerosis. 2014 World J Pediatr pmid:24801235
Schlosser K et al. Surgical treatment of tertiary hyperparathyroidism: the choice of procedure matters! 2007 World J Surg pmid:17665243
Platz KP et al. Management of acute steroid-resistant rejection after liver transplantation. 1996 World J Surg pmid:8798364
Sutherland DE et al. Pancreas transplantation for treatment of diabetes mellitus. 2001 World J Surg pmid:11344403
Kato T et al. Intestinal and multivisceral transplantation. 2002 World J Surg pmid:11865353
Motoyama K et al. Pretransplant intrathymic inoculation of donor antigen combined with FK506 treatment: prolongation of survival of cardiac, but not renal, allografts in rats. 1995 Mar-Apr World J Surg pmid:7538717
Ramakant P and Agarwal G Surgical treatment of tertiary hyperparathyroidism: the choice of procedure matters: surgical management of tertiary hyperparathyroidism: an enigma. 2008 World J Surg pmid:18404286
Montenegro F et al. Surgical treatment of tertiary hyperparathyroidism: the choice of procedure matters! 2008 World J Surg pmid:18204944
Jordan ML et al. The use of tacrolimus in renal transplantation. 1996 World J Urol pmid:8873438
Yang J et al. Zinc finger protein A20 protects rats against chronic liver allograft dysfunction. 2012 World J. Gastroenterol. pmid:22826618
Zhou J et al. Conversion to sirolimus immunosuppression in liver transplantation recipients with hepatocellular carcinoma: Report of an initial experience. 2006 World J. Gastroenterol. pmid:16718799
Li DW et al. Risk factors for new onset diabetes mellitus after liver transplantation: A meta-analysis. 2015 World J. Gastroenterol. pmid:26034369
Higashi H et al. First successful perinatal management of pregnancy after ABO-incompatible liver transplantation. 2017 World J. Gastroenterol. pmid:28210092
Indriolo A and Ravelli P Clinical management of inflammatory bowel disease in the organ recipient. 2014 World J. Gastroenterol. pmid:24707135
Shen T et al. Reversible sinusoidal obstruction syndrome associated with tacrolimus following liver transplantation. 2015 World J. Gastroenterol. pmid:26034381