Kuo CJ et al. |
Rapamycin selectively inhibits interleukin-2 activation of p70 S6 kinase. |
1992 |
Nature |
pmid:1614535
|
Moutabarrik A et al. |
In vitro FK506 kidney tubular cell toxicity. |
1992 |
Transpl. Int. |
pmid:14621743
|
Moutabarrik A et al. |
FK506 mechanism of nephrotoxicity: stimulatory effect on endothelin secretion by cultured kidney cells. |
1992 |
Transpl. Int. |
pmid:14621744
|
Stangl MJ et al. |
The use of FK506 and RS61443 for reversal of small-bowel rejection. |
1992 |
Transpl. Int. |
pmid:14621800
|
Kusne S et al. |
Infections during a randomized trial comparing cyclosporine to FK 506 immunosuppression in liver transplantation. |
1992 |
Transplant. Proc. |
pmid:1371626
|
Wijnen RM et al. |
Toxicology of FK506 in the cynomolgus monkey: a clinical, biochemical, and histopathological study. |
1992 |
Transpl. Int. |
pmid:14621844
|
Lee C et al. |
FK-506 binding protein from Tolypocladium inflatum: resistance of FKBP/FK-506 complex against proteolysis. |
1992 |
Biochem. Biophys. Res. Commun. |
pmid:1371677
|
Jiang H et al. |
Control of humoral and cellular immunity-mediated accelerated heart allograft rejection in sensitized rats by low dose FK 506 and splenectomy. |
1992 |
Transpl. Int. |
pmid:14621859
|
Edkins RD et al. |
Comparison of cyclosporine and FK506 effects on glutathione levels in rat cochlea, brain, liver and kidney. |
1992 |
Biochem. Pharmacol. |
pmid:1371687
|
Kobayashi N et al. |
Abdominal organ cluster transplantation in pigs and FK506. |
1992 |
Transpl. Int. |
pmid:14621861
|
Galat A et al. |
A rapamycin-selective 25-kDa immunophilin. |
1992 |
Biochemistry |
pmid:1371698
|
Hanawa H et al. |
An immunosuppressant compound, FK-506, prevents the progression of autoimmune myocarditis in rats. |
1992 |
Clin. Immunol. Immunopathol. |
pmid:1371730
|
Hiraoka Y et al. |
The effects of FK-506, a novel and potent immunosuppressant, upon murine Coxsackievirus B3 myocarditis. |
1992 |
J. Pharmacol. Exp. Ther. |
pmid:1372051
|
Chen TS et al. |
Microbial transformation of immunosuppressive compounds. I. Desmethylation of FK506 and immunomycin (FR 900520) by Actinoplanes sp. ATCC 53771. |
1992 |
J. Antibiot. |
pmid:1372307
|
Morisaki M and Arai T |
Identity of immunosuppressant FR-900520 with ascomycin. |
1992 |
J. Antibiot. |
pmid:1372308
|
Sakr M et al. |
The protective effect of FK506 pretreatment against renal ischemia/reperfusion injury in rats. |
1992 |
Transplantation |
pmid:1374948
|
Lepre CA et al. |
Solution structure of FK506 bound to FKBP-12. |
1992 |
FEBS Lett. |
pmid:1375171
|
Ruff VA et al. |
FKBP-12 is not an inhibitor of protein kinase C. |
1992 |
Immunol. Invest. |
pmid:1375189
|
Kawaguchi S |
[Effects of FK506 on aminonucleoside-induced nephrotic rats]. |
1992 |
Nihon Jinzo Gakkai Shi |
pmid:1375300
|
Sigal NH and Dumont FJ |
Cyclosporin A, FK-506, and rapamycin: pharmacologic probes of lymphocyte signal transduction. |
1992 |
Annu. Rev. Immunol. |
pmid:1375473
|
Chen TS et al. |
Microbial transformation of immunosuppressive compounds. II. Specific desmethylation of 13-methoxy group of FK 506 and FR 900520 by an unidentified Actinomycete ATCC 53828 [corrected]. |
1992 |
J. Antibiot. |
pmid:1375593
|
Yagihashi A et al. |
Changes in cell surface markers in human small bowel transplantation with FK 506. |
1992 |
Transplant. Proc. |
pmid:1376522
|
Abu-Elmagd K et al. |
Management of intestinal transplantation in humans. |
1992 |
Transplant. Proc. |
pmid:1376523
|
Takaori K et al. |
Basic study on immunologic effects of cyclosporine and FK 506 for application to pancreatic transplantation. |
1992 |
Transplant. Proc. |
pmid:1376531
|
Ohtsuka S et al. |
The effect of short-term FK 506 therapy on pancreas transplantation using the cuff technique in rats. |
1992 |
Transplant. Proc. |
pmid:1376532
|
Demetris AJ et al. |
Donor dendritic cells after liver and heart allotransplantation under short-term immunosuppression. |
1992 |
Lancet |
pmid:1376851
|
Ichihashi T et al. |
Haemolytic uraemic syndrome during FK506 therapy. |
1992 |
Lancet |
pmid:1376852
|
O'Keefe SJ et al. |
FK-506- and CsA-sensitive activation of the interleukin-2 promoter by calcineurin. |
1992 |
Nature |
pmid:1377361
|
Souza ER et al. |
Acute effects of FK 506 on glomerular hemodynamics. |
1992 |
Transplant. Proc. |
pmid:1281585
|
Hanke JH et al. |
FK506 and rapamycin selectively enhance degradation of IL-2 and GM-CSF mRNA. |
1992 |
Lymphokine Cytokine Res. |
pmid:1281674
|
Logan TM et al. |
Side chain and backbone assignments in isotopically labeled proteins from two heteronuclear triple resonance experiments. |
1992 |
FEBS Lett. |
pmid:1281793
|
Bergstrand H et al. |
Modulation of neutrophil superoxide generation by inhibitors of protein kinase C, calmodulin, diacylglycerol and myosin light chain kinases, and peptidyl prolyl cis-trans isomerase. |
1992 |
J. Pharmacol. Exp. Ther. |
pmid:1281879
|
DiLella AG et al. |
Chromosomal band assignments of the genes encoding human FKBP12 and FKBP13. |
1992 |
Biochem. Biophys. Res. Commun. |
pmid:1281998
|
Sawada M et al. |
Down regulation of CD4 expression in cultured microglia by immunosuppressants and lipopolysaccharide. |
1992 |
Biochem. Biophys. Res. Commun. |
pmid:1282000
|
Minoda M et al. |
Effects of gamma-interferon and FK506 on resting B cell proliferation of New Zealand black/white F1 mice. |
1992 |
Microbiol. Immunol. |
pmid:1282197
|
Kumano K et al. |
[Functional and morphological changes in rat kidney induced by FK506 and its reversal by various vasodilators]. |
1992 |
Nippon Hinyokika Gakkai Zasshi |
pmid:1379657
|
Woodle ES et al. |
FK506: inhibition of humoral mechanisms of hepatic allograft rejection. |
1992 |
Transplantation |
pmid:1379749
|
Sato K et al. |
Effectiveness of triple drug immunosuppression for pancreaticoduodenal allotransplantation in dogs. |
1992 |
Transplant. Proc. |
pmid:1379753
|
Kobayashi N et al. |
Abdominal organ cluster transplantation in pigs receiving FK 506. |
1992 |
Transplant. Proc. |
pmid:1379754
|
Yoshimura R et al. |
A comparative study of cyclosporine vs FK 506: role of kidney microsomal cytochrome P-450. |
1992 |
Transplant. Proc. |
pmid:1379755
|
Yamada K et al. |
FK 506-induced juxtaglomerular apparatus hyperplasia and tubular damage in rat kidney--morphologic and biologic analysis. |
1992 |
Transplant. Proc. |
pmid:1379756
|
Fukuse T et al. |
Optimal dose of FK 506 in canine lung allotransplantation. |
1992 |
Transplant. Proc. |
pmid:1379757
|
Wada H et al. |
Combination use of suboptimal doses of FK 506 and cyclosporine in canine lung transplantation. |
1992 |
Transplant. Proc. |
pmid:1379758
|
Friccius H et al. |
The effects of the antifungal azoles itraconazole, fluconazole, ketoconazole and miconazole on cytokine gene expression in human lymphoid cells. |
1992 |
Int. J. Immunopharmacol. |
pmid:1380951
|
Dumont FJ et al. |
The immunosuppressive and toxic effects of FK-506 are mechanistically related: pharmacology of a novel antagonist of FK-506 and rapamycin. |
1992 |
J. Exp. Med. |
pmid:1380976
|
Norris AA et al. |
Protective effects of cyclophosphamide, cyclosporin A and FK506 against antigen-induced lung eosinophilia in guinea-pigs. |
1992 |
Clin. Exp. Immunol. |
pmid:1381297
|
Karpas A et al. |
Inhibition of human immunodeficiency virus and growth of infected T cells by the immunosuppressive drugs cyclosporin A and FK 506. |
1992 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:1381509
|
Yatscoff RW and Shaw LM |
Therapeutic monitoring of cyclosporine, FK-506, and rapamycin. |
1992 |
Ther Drug Monit |
pmid:1381530
|
Arceci RJ et al. |
Immunosuppressants FK506 and rapamycin function as reversal agents of the multidrug resistance phenotype. |
1992 |
Blood |
pmid:1381629
|
Pahl A and Keller U |
FK-506-binding proteins from streptomycetes producing immunosuppressive macrolactones of the FK-506 type. |
1992 |
J. Bacteriol. |
pmid:1381710
|
Siekierka JJ and Sigal NH |
FK-506 and cyclosporin A: immunosuppressive mechanism of action and beyond. |
1992 |
Curr. Opin. Immunol. |
pmid:1384551
|
Hultsch T et al. |
The effect of the immunophilin ligands rapamycin and FK506 on proliferation of mast cells and other hematopoietic cell lines. |
1992 |
Mol. Biol. Cell |
pmid:1384815
|
Petros AM et al. |
Identification of solvent-exposed regions of an FK-506 analog, ascomycin, bound to FKBP using a paramagnetic probe. |
1992 |
J. Biomol. NMR |
pmid:1384850
|
Liu J et al. |
The effects of FK-506 and cyclosporin A on the proliferation of PHA-stimulated T cells in response to IL-2, IL-4 or IL-6. |
1992 |
Int. Arch. Allergy Immunol. |
pmid:1384862
|
Mochizuki M et al. |
Preclinical and clinical study of FK506 in uveitis. |
1992 |
Curr. Eye Res. |
pmid:1385045
|
Chung J et al. |
Rapamycin-FKBP specifically blocks growth-dependent activation of and signaling by the 70 kd S6 protein kinases. |
1992 |
Cell |
pmid:1377606
|
Mizuno K et al. |
Modulation of multidrug resistance by immunosuppressive agents: cyclosporin analogues, FK506 and mizoribine. |
1992 Jan-Feb |
Anticancer Res. |
pmid:1373592
|
Arai S et al. |
The impact of FK506 on graft coronary disease of rat cardiac allograft--a comparison with cyclosporine. |
1992 Jul-Aug |
J. Heart Lung Transplant. |
pmid:1379829
|
Fagiuoli S et al. |
FK 506: a new immunosuppressive agent for organ transplantation. Pharmacology, mechanism of action and clinical applications. |
1992 Jul-Aug |
Ital J Gastroenterol |
pmid:1381245
|
Tong J et al. |
Effect of FK-506 and cyclosporin A on in vitro CFU-GM growth in severe aplastic anemia patients. |
1992 Jul-Aug |
Haematologica |
pmid:1385279
|
Nazer H et al. |
FK 506 associated disorders in liver transplantation. |
1992 May-Jun |
J. Gastroenterol. Hepatol. |
pmid:1377038
|
Bowman H and Lennard TW |
Immunosuppressive drugs. |
1992 Nov 4-17 |
Br J Hosp Med |
pmid:1282440
|
Sattler M et al. |
Cytochrome P-450 3A enzymes are responsible for biotransformation of FK506 and rapamycin in man and rat. |
1992 Sep-Oct |
Drug Metab. Dispos. |
pmid:1385058
|
Watanabe K et al. |
Fate of long-surviving allografts in tolerant recipients induced by fractionated lymphoid irradiation, donor bone marrow cell infusion, and FK 506 after retransplantation in dogs. |
1993 |
Transplant. Proc. |
pmid:7679813
|
Valdivia LA et al. |
Hamster-to-rat liver xenografts protect extrahepatic organs from rejection. |
1993 |
Transplant. Proc. |
pmid:7679816
|
Murase N et al. |
Effect of FK 506 and antiproliferative agents for heart and liver xenotransplantation from hamster to rat. |
1993 |
Transplant. Proc. |
pmid:7679817
|
Schreier MH et al. |
Inhibition of T-cell signaling pathways by immunophilin drug complexes: are side effects inherent to immunosuppressive properties? |
1993 |
Transplant. Proc. |
pmid:7679818
|
Fung J et al. |
Randomized trial in primary liver transplantation under immunosuppression with FK 506 or cyclosporine. |
1993 |
Transplant. Proc. |
pmid:7680146
|
Shibata T et al. |
Does FK 506 accelerate the development of coronary artery disease in the transplanted heart as well as the native heart? |
1993 |
Transplant. Proc. |
pmid:7680147
|
Todo S et al. |
Intestinal transplantation in humans under FK 506. |
1993 |
Transplant. Proc. |
pmid:7680148
|
Takahara S et al. |
[Blood level monitoring of FK506 on kidney transplant recipients]. |
1993 |
Nippon Hinyokika Gakkai Zasshi |
pmid:7504758
|
Lieberman I et al. |
Synergy between tetrandrine and FK506 in prevention of diabetes in BB rats. |
1993 |
Life Sci. |
pmid:7504774
|
Müller MK et al. |
[Pathophysiologic concepts and protective possibilities in experimental pancreatic lesions]. |
1993 |
Z Gastroenterol |
pmid:7504856
|
Panis Y and Valleur P |
[Small intestine transplantation. Experimental and clinical results]. |
1993 |
Ann Chir |
pmid:7504899
|
Bruserud O and Pawelec G |
Cyclosporine A and FK506 show similar immunosuppressive effects on long-term in vitro T-cell proliferation. |
1993 |
Int. J. Immunopharmacol. |
pmid:7682202
|
Winkler M et al. |
Anaemia associated with FK 506 immunosuppression. |
1993 |
Lancet |
pmid:7682273
|
Lundemose AG et al. |
Chlamydia trachomatis Mip-like protein has peptidyl-prolyl cis/trans isomerase activity that is inhibited by FK506 and rapamycin and is implicated in initiation of chlamydial infection. |
1993 |
Mol. Microbiol. |
pmid:7682281
|
Wiesner RH et al. |
Early cellular rejection treated with high-dose intravenous corticosteroid therapy is associated with a decrease in the incidence of steroid-resistant rejection and graft failure from rejection. |
1993 |
Transplant. Proc. |
pmid:7682352
|
McDiarmid SV et al. |
FK506 conversion for intractable rejection of the liver allograft. |
1993 |
Transpl. Int. |
pmid:7507675
|
Akita K and Mandel TE |
Effect of FK 506 and anti-CD4 monoclonal antibody treatment on xenografts of organ-cultured fetal pig pancreas and host lymphoid populations. |
1993 |
Transplant. Proc. |
pmid:7692650
|
Liu J |
FK506 and ciclosporin: molecular probes for studying intracellular signal transduction. |
1993 |
Trends Pharmacol. Sci. |
pmid:7692652
|
David M et al. |
[Changes in cervix cytology in women with liver transplants treated with immunosuppressive therapy]. |
1993 |
Zentralbl Gynakol |
pmid:7692689
|
Wallemacq PE and Reding R |
FK506 (tacrolimus), a novel immunosuppressant in organ transplantation: clinical, biomedical, and analytical aspects. |
1993 |
Clin. Chem. |
pmid:7693372
|
Ochiai T et al. |
Combination of immunosuppressive drugs for organ transplantation. |
1993 |
Ann. N. Y. Acad. Sci. |
pmid:7509136
|
Wiederrecht G et al. |
The mechanism of action of FK-506 and cyclosporin A. |
1993 |
Ann. N. Y. Acad. Sci. |
pmid:7509138
|
Morikawa K et al. |
Immunosuppressive activity of fosfomycin on human T-lymphocyte function in vitro. |
1993 |
Antimicrob. Agents Chemother. |
pmid:7509146
|
Jachez B et al. |
Reversion of the P-glycoprotein-mediated multidrug resistance of cancer cells by FK-506 derivatives. |
1993 |
Anticancer Drugs |
pmid:7683935
|
Shapiro R et al. |
FK 506 interaction with danazol. |
1993 |
Lancet |
pmid:7684106
|
Becker JW et al. |
FK-506-binding protein: three-dimensional structure of the complex with the antagonist L-685,818. |
1993 |
J. Biol. Chem. |
pmid:7684380
|
Thomson AW et al. |
Effects of combined administration of FK 506 and the purine biosynthesis inhibitors mizoribine or mycophenolic acid on lymphocyte DNA synthesis and T cell activation molecule expression in human mixed lymphocyte cultures. |
1993 |
Transpl. Immunol. |
pmid:7521738
|
Matsuura T et al. |
Organ-specific unresponsiveness induced by intrathymic injection of donor bone marrow cells and a short course of immunosuppression in the rat heart transplantation model. |
1993 |
Transpl. Immunol. |
pmid:7521742
|
Fujisawa T et al. |
Dose study of the immunosuppression of FK 506 in canine lung allo-transplantation. |
1993 |
Surg. Today |
pmid:7686416
|
Ueno M et al. |
[Immunosuppressive effect in combination therapy of cyclosporine A, FK506 and 15-deoxyspergualin on a pancreatic islet xenotransplantation]. |
1993 |
Nihon Geka Gakkai Zasshi |
pmid:7686615
|
Thomson AW et al. |
FK 506: a novel immunosuppressant for treatment of autoimmune disease. Rationale and preliminary clinical experience at the University of Pittsburgh. |
1993 |
Springer Semin. Immunopathol. |
pmid:7686690
|
Valdivia LA et al. |
Dendritic cell replacement in long-surviving liver and cardiac xenografts. |
1993 |
Transplantation |
pmid:7689265
|
Odocha O et al. |
Posttransplant diabetes mellitus in African Americans after renal transplantation under FK 506 immunosuppression. |
1993 |
Transplant. Proc. |
pmid:7689268
|
Odocha O et al. |
Serum cholesterol levels in African Americans after renal transplantation under FK 506 immunosuppression. |
1993 |
Transplant. Proc. |
pmid:7689269
|
Hom JT and Estridge T |
FK506 and rapamycin modulate the functional activities of human peripheral blood eosinophils. |
1993 |
Clin. Immunol. Immunopathol. |
pmid:7690315
|
Olivera DL et al. |
Divergent effects of rapamycin on mouse and rat cells following mitogenic stimulation. |
1993 |
Clin. Immunol. Immunopathol. |
pmid:7690317
|
Whitington PF et al. |
Orthotopic auxiliary liver transplantation for Crigler-Najjar syndrome type 1. |
1993 |
Lancet |
pmid:7690444
|