tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (2)
- Am. J. Physiol. Renal Physiol. (1)
- Drug Metab. Dispos. (1)
- Others (1)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Slocum AMY | A surgeon's nightmare: pyoderma gangrenosum with pathergy effect mimicking necrotising fasciitis. | 2017 | BMJ Case Rep | pmid:29269363 |
| Charlton M et al. | Everolimus Is Associated With Less Weight Gain Than Tacrolimus 2 Years After Liver Transplantation: Results of a Randomized Multicenter Study. | 2017 | Transplantation | pmid:28817434 |
| Ghaffari R et al. | Tacrolimus Eye Drops as Adjunct Therapy in Severe Corneal Endothelial Rejection Refractory to Corticosteroids. | 2017 | Cornea | pmid:28817391 |
| Kumai Y et al. | Reversible Cerebral Vasoconstriction Syndrome After Heart Transplantation: A Case Report. | 2017 | Transplant. Proc. | pmid:29198694 |
| Savić V et al. | Tacrolimus loaded biocompatible lecithin-based microemulsions with improved skin penetration: Structure characterization and in vitro/in vivo performances. | 2017 | Int J Pharm | pmid:28711641 |
| Groll AH et al. | Pharmacokinetic Assessment of Drug-Drug Interactions of Isavuconazole With the Immunosuppressants Cyclosporine, Mycophenolic Acid, Prednisolone, Sirolimus, and Tacrolimus in Healthy Adults. | 2017 | Clin Pharmacol Drug Dev | pmid:27273343 |
| BenÃtez C et al. | Letter: sublingual dosing of tacrolimus in transplant patients-interesting concept to overcome first pass effects. Authors' reply. | 2017 | Aliment. Pharmacol. Ther. | pmid:28589580 |
| Justice JA et al. | Disruption of K2.1 somato-dendritic clusters prevents the apoptogenic increase of potassium currents. | 2017 | Neuroscience | pmid:28461216 |
| Lu XF et al. | Use of a semi-physiological pharmacokinetic model to investigate the influence of itraconazole on tacrolimus absorption, distribution and metabolism in mice. | 2017 | Xenobiotica | pmid:27533047 |
| O'Leary JG | Editorial: tacrolimus-how low can you go? | 2017 | Aliment. Pharmacol. Ther. | pmid:28589579 |
| Kodama S et al. | Tacrolimus-Induced Reversible Cerebral Vasoconstriction Syndrome with Delayed Multi-Segmental Vasoconstriction. | 2017 | J Stroke Cerebrovasc Dis | pmid:28342655 |
| Lichtenberg S et al. | The incidence of post-transplant cancer among kidney transplant recipients is associated with the level of tacrolimus exposure during the first year after transplantation. | 2017 | Eur. J. Clin. Pharmacol. | pmid:28342067 |
| Salgüero Fernández I et al. | Rapidly progressive infiltrated plaques in a transplant recipient. | 2017 | Actas Dermosifiliogr | pmid:27677210 |
| Stojanovic J et al. | Immune Desensitization Allows Pediatric Blood Group Incompatible Kidney Transplantation. | 2017 | Transplantation | pmid:27463537 |
| Basu B et al. | Long-term efficacy and safety of common steroid-sparing agents in idiopathic nephrotic children. | 2017 | Clin. Exp. Nephrol. | pmid:27108294 |
| Grant CR et al. | Immunosuppressive drugs affect interferon (IFN)-γ and programmed cell death 1 (PD-1) kinetics in patients with newly diagnosed autoimmune hepatitis. | 2017 | Clin. Exp. Immunol. | pmid:28257599 |
| Wang J et al. | Metabolic network model guided engineering ethylmalonyl-CoA pathway to improve ascomycin production in Streptomyces hygroscopicus var. ascomyceticus. | 2017 | Microb. Cell Fact. | pmid:28974216 |
| Ordóñez-Robles M et al. | Analysis of the Pho regulon in Streptomyces tsukubaensis. | 2017 | Microbiol. Res. | pmid:28942849 |
| Cohen JB et al. | Belatacept Compared With Tacrolimus for Kidney Transplantation: A Propensity Score Matched Cohort Study. | 2017 | Transplantation | pmid:27941427 |
| Baas M et al. | Unique clinical conditions associated with different acinar regions of fibrosis in long-term surviving pediatric liver grafts. | 2017 | Pediatr Transplant | pmid:28627016 |