Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with tacrolimus
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Ohara M et al. | Myasthenia Gravis Complicated with Peripheral T-cell Lymphoma, Not Otherwise Specified (PTCL-NOS), Following Thymectomy and Longstanding Tacrolimus Therapy. | 2018 | Intern. Med. | pmid:29269644 |
Kirchhof J et al. | Learned immunosuppressive placebo responses in renal transplant patients. | 2018 | Proc. Natl. Acad. Sci. U.S.A. | pmid:29610294 |
Ixtlapale-Carmona X et al. | Graft immunologic events in deceased donor kidney transplant recipients with preformed HLA-donor specific antibodies. | 2018 | Transpl. Immunol. | pmid:28974434 |
Li YM et al. | Impact of immunosuppressive drugs on circulating Tfh cells in kidney transplant recipients: A pilot study. | 2018 | Transpl. Immunol. | pmid:28974433 |
Zhao J et al. | Comparison of different regimens of pimecrolimus 1% cream in the treatment of facial seborrheic dermatitis. | 2018 | J Cosmet Dermatol | pmid:28589618 |
Shank BR et al. | Interdisciplinary implementation of tacrolimus intravenous standard concentration in hematopoietic stem cell transplantation recipients. | 2018 | J Oncol Pharm Pract | pmid:28554241 |
González-VÃlchez F et al. | Efficacy and Safety of de Novo and Early Use of Extended-release Tacrolimus in Heart Transplantation. | 2018 | Rev Esp Cardiol (Engl Ed) | pmid:28545984 |
Fonseca ACRG et al. | Calcineurin is an important factor involved in glucose uptake in human adipocytes. | 2018 | Mol. Cell. Biochem. | pmid:29380240 |
Kimura Y et al. | Profiling the immunotoxicity of chemicals based on in vitro evaluation by a combination of the Multi-ImmunoTox assay and the IL-8 Luc assay. | 2018 | Arch. Toxicol. | pmid:29594315 |
Vandenbussche C et al. | Tacrolimus-induced nephrotoxicity in mice is associated with microRNA deregulation. | 2018 | Arch. Toxicol. | pmid:29362864 |
Li P et al. | Risk factors for BK virus infection in living-donor renal transplant recipients: a single-center study from China. | 2018 | Ren Fail | pmid:30052479 |
Thoms S et al. | Tacrolimus inhibits angiogenesis and induces disaggregation of endothelial cells in spheroids - Toxicity testing in a 3D cell culture approach. | 2018 | Toxicol In Vitro | pmid:30048735 |
Cai W et al. | Limited Sampling Strategy for Estimating Mycophenolic Acid Exposure on Day 7 Post-Transplant for Two Mycophenolate Mofetil Formulations Derived From 20 Chinese Renal Transplant Recipients. | 2018 | Transplant. Proc. | pmid:29735215 |
Chung YW et al. | Tacrolimus-Induced Apoptosis is Mediated by Endoplasmic Reticulum-derived Calcium-dependent Caspases-3,-12 in Jurkat Cells. | 2018 | Transplant. Proc. | pmid:29731088 |
Youssef A et al. | Angiolymphoid hyperplasia with eosinophilia: a case report. | 2018 | J Med Case Rep | pmid:29606120 |
Hu R et al. | CYP3A5*3 and ABCB1 61A>G Significantly Influence Dose-adjusted Trough Blood Tacrolimus Concentrations in the First Three Months Post-Kidney Transplantation. | 2018 | Basic Clin. Pharmacol. Toxicol. | pmid:29603629 |
Woodworth MH et al. | Tacrolimus concentration to dose ratio in solid organ transplant patients treated with fecal microbiota transplantation for recurrent Clostridium difficile infection. | 2018 | Transpl Infect Dis | pmid:29446866 |
Konma J et al. | Efficacy and safety of combination therapy with prednisolone and oral tacrolimus for progressive interstitial pneumonia with systemic sclerosis: A retrospective study. | 2018 | Mod Rheumatol | pmid:29442534 |
Vosough M and Tehrani SM | Development of a fast HPLC-DAD method for simultaneous quantitation of three immunosuppressant drugs in whole blood samples using intelligent chemometrics resolving of coeluting peaks in the presence of blood interferences. | 2018 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:29241087 |
Hashemian MN et al. | Topical Tacrolimus as Adjuvant Therapy to Corticosteroids in Acute Endothelial Graft Rejection After Penetrating Keratoplasty: A Randomized Controlled Trial. | 2018 | Cornea | pmid:29215395 |