tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Moura Penteado LA et al. | Evaluation of the effect of tacrolimus on periodontitis induced in rats. | 2017 | Arch. Oral Biol. | pmid:28399470 |
| Gouvêa ALF et al. | BK polyomavirus nephropathy in two kidney transplant patients with distinct diagnostic strategies for BK virus and similar clinical outcomes: two case reports. | 2017 | J Med Case Rep | pmid:28535782 |
| Kawamura H et al. | Rapid Induction Therapy with Oral Tacrolimus in Elderly Patients with Refractory Ulcerative Colitis Can Easily Lead to Elevated Tacrolimus Concentrations in Blood: A Report of 5 Cases. | 2017 | Am J Case Rep | pmid:28411286 |
| Sinha A et al. | Mycophenolate mofetil is inferior to tacrolimus in sustaining remission in children with idiopathic steroid-resistant nephrotic syndrome. | 2017 | Kidney Int. | pmid:28318625 |
| Saeki K et al. | Endobronchial Lesions of Mycobacterium abscessus Infection in an Immunocompromised Patient. | 2017 | Am. J. Respir. Crit. Care Med. | pmid:28199133 |
| Ericson JE et al. | A Systematic Literature Review Approach to Estimate the Therapeutic Index of Selected Immunosuppressant Drugs After Renal Transplantation. | 2017 | Ther Drug Monit | pmid:28081041 |
| Miyazaki D et al. | Steroid-Sparing Effect of 0.1% Tacrolimus Eye Drop for Treatment of Shield Ulcer and Corneal Epitheliopathy in Refractory Allergic Ocular Diseases. | 2017 | Ophthalmology | pmid:28017421 |
| De Majumdar S et al. | A Low Concentration of Tacrolimus/Semifluorinated Alkane (SFA) Eyedrop Suppresses Intraocular Inflammation in Experimental Models of Uveitis. | 2017 | Curr. Mol. Med. | pmid:28782485 |
| Larche M and McGonagle D | A case of resistant spondyloarthritis (SpA) that responded to tacrolimus and mycophenolate treatment initiated at the time of renal transplantation for unrelated renal failure. | 2017 | Scand. J. Rheumatol. | pmid:26971928 |
| Shirai T et al. | Successful treatment with tacrolimus in TAFRO syndrome: two case reports and literature review. | 2018 | Medicine (Baltimore) | pmid:29879072 |
| Liu L et al. | New insights of subfertility among transplanted women: Immunosuppressive drug FK506 leads to calcium leak and oocyte activation before fertilization. | 2018 | J. Cell. Biochem. | pmid:29131377 |
| Pham TT et al. | Tissue adhesive FK506-loaded polymeric nanoparticles for multi-layered nano-shielding of pancreatic islets to enhance xenograft survival in a diabetic mouse model. | 2018 | Biomaterials | pmid:29128846 |
| Kamanamool N et al. | Comparison of disease activity between tacrolimus and mycophenolate mofetil in lupus nephritis: a randomized controlled trial. | 2018 | Lupus | pmid:29105558 |
| Fu J et al. | Transcriptomic analysis uncovers novel synergistic mechanisms in combination therapy for lupus nephritis. | 2018 | Kidney Int. | pmid:29102373 |
| Bond MMK et al. | Cyclosporine Versus Tacrolimus: Which Calcineurin Inhibitor Has Influence on Cytomegalovirus Infection in Cardiac Transplantation? | 2018 | Transplant. Proc. | pmid:29661443 |
| Lee WS et al. | Tacrolimus regulates endoplasmic reticulum stress-mediated osteoclastogenesis and inflammation: In vitro and collagen-induced arthritis mouse model. | 2018 | Cell Biol. Int. | pmid:28833755 |
| Quintero J et al. | Conversion from twice-daily to once-daily tacrolimus formulation in pediatric liver transplant recipients - a long-term prospective study. | 2018 | Transpl. Int. | pmid:28833714 |
| Zeng K et al. | Dissolution Test of Tacrolimus Capsule: Effects of Filtration and Glass Adsorption. | 2018 | AAPS PharmSciTech | pmid:28828626 |
| Kim JP et al. | The effect of full dose composite tissue allotransplantation immunosuppression on allograft motor nerve regeneration in a rat sciatic nerve model. | 2018 | Microsurgery | pmid:28792625 |
| Jiang JW et al. | Optimal immunosuppressor induces stable gut microbiota after liver transplantation. | 2018 | World J. Gastroenterol. | pmid:30228781 |
| Harada N et al. | Serum Asunaprevir and Daclatasvir Concentrations and Outcomes in Patients with Recurrent Hepatitis C Who Have Undergone Living Donor Liver Transplantation. | 2018 | Anticancer Res. | pmid:30194210 |
| Sahu S et al. | Active natural oil-based nanoemulsion containing tacrolimus for synergistic antipsoriatic efficacy. | 2018 | Nanomedicine (Lond) | pmid:30188761 |
| Min S et al. | A randomized clinical trial of age and genotype-guided tacrolimus dosing after pediatric solid organ transplantation. | 2018 | Pediatr Transplant | pmid:30178515 |
| Gu B et al. | Exploration of Fecal Microbiota Transplantation in the Treatment of Refractory Diarrhea After Renal Transplantation. | 2018 | Transplant. Proc. | pmid:29880353 |
| Lee H et al. | Thymoglobulin Versus Basiliximab Induction Therapy in Low-Risk Kidney Transplant Recipients: A Single-Center Experience. | 2018 | Transplant. Proc. | pmid:29880348 |
| La Maestra S et al. | Brain microglia activation induced by intracranial administration of oligonucleotides and its pharmacological modulation. | 2018 | Drug Deliv Transl Res | pmid:29869293 |
| Marquet P et al. | Pharmacokinetic Therapeutic Drug Monitoring of Advagraf in More Than 500 Adult Renal Transplant Patients, Using an Expert System Online. | 2018 | Ther Drug Monit | pmid:29505493 |
| Chen J et al. | Controlled dimerization of insulin-like growth factor-1 and insulin receptors reveals shared and distinct activities of holo and hybrid receptors. | 2018 | J. Biol. Chem. | pmid:29330302 |
| Marquet P et al. | Comparative clinical trial of the variability factors of the exposure indices used for the drug monitoring of two tacrolimus formulations in kidney transplant recipients. | 2018 | Pharmacol. Res. | pmid:29229354 |
| Zhang T et al. | Association of donor small ubiquitin-like modifier 4 rs237025 genetic variant with tacrolimus elimination in the early period after liver transplantation. | 2018 | Liver Int. | pmid:28941036 |
| Ichinose K et al. | The efficacy of adjunct tacrolimus treatment in pregnancy outcomes in patients with systemic lupus erythematosus. | 2018 | Lupus | pmid:29665758 |
| Ishikawa S et al. | Management of Juvenile Idiopathic Arthritis in ABO-incompatible Kidney Transplantation: A Case Report. | 2018 | Transplant. Proc. | pmid:29661455 |
| Moura Neto A et al. | Frequency of Thyroid Dysfunction in Patients With Diabetes Mellitus Before and After Liver Transplantation. | 2018 | Transplant. Proc. | pmid:29661439 |
| Moura Neto A et al. | Clinical Profile of Patients With Diabetes Mellitus and Liver Transplantation: Results After a Multidisciplinary Team Intervention. | 2018 | Transplant. Proc. | pmid:29661438 |
| Mei S et al. | Simultaneous determination of cyclosporine and tacrolimus in human whole blood by ultra-high performance liquid chromatography tandem mass spectrometry and comparison with a chemiluminescence microparticle immunoassay. | 2018 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:29704799 |
| Stanton BZ et al. | Chemically induced proximity in biology and medicine. | 2018 | Science | pmid:29590011 |
| Foroutan A et al. | Successful treatment of allergic conjunctival granuloma by topical tacrolimus: A clinicopathologic case report. | 2018 | Indian J Ophthalmol | pmid:29582827 |
| Efe C et al. | Tacrolimus and Mycophenolate Mofetil as Second-Line Therapies for Pediatric Patients with Autoimmune Hepatitis. | 2018 | Dig. Dis. Sci. | pmid:29569003 |
| Bittersohl H et al. | A simple and highly sensitive on-line column extraction liquid chromatography-tandem mass spectrometry method for the determination of protein-unbound tacrolimus in human plasma samples. | 2018 | J Chromatogr A | pmid:29544893 |
| Okada K et al. | EBV-positive PEL-like lymphoma that developed in the course of antisynthetase syndrome treated with tacrolimus. | 2018 | Int. J. Hematol. | pmid:29516290 |
| Sano H et al. | T-cell-replete haploidentical stem cell transplantation using low-dose antithymocyte globulin in children with relapsed or refractory acute leukemia. | 2018 | Int. J. Hematol. | pmid:29508228 |
| Kociszewska-Najman B et al. | Low Transfer of Tacrolimus and Its Metabolites into Colostrum of Graft Recipient Mothers. | 2018 | Nutrients | pmid:29495430 |
| Ghadimi M et al. | Tacrolimus interaction with oral oestrogen in kidney transplant recipients: A case-control study. | 2018 | J Clin Pharm Ther | pmid:29492991 |
| Li X et al. | Association of the PPARγ/PI3K/Akt pathway with the cardioprotective effects of tacrolimus in myocardial ischemic/reperfusion injury. | 2018 | Mol Med Rep | pmid:29488613 |
| Takeuchi T et al. | Post-marketing surveillance study of the long-term use of mizoribine for the treatment of lupus nephritis: 2-Year results. | 2018 | Mod Rheumatol | pmid:28722500 |
| Takeuchi T et al. | Safety and effectiveness of tacrolimus add-on therapy for rheumatoid arthritis patients without an adequate response to biological disease-modifying anti-rheumatic drugs (DMARDs): Post-marketing surveillance in Japan. | 2018 | Mod Rheumatol | pmid:28649878 |
| Oetting WS et al. | Attempted validation of 44 reported SNPs associated with tacrolimus troughs in a cohort of kidney allograft recipients. | 2018 | Pharmacogenomics | pmid:29318894 |
| Rayar M et al. | High Intrapatient Variability of Tacrolimus Exposure in the Early Period After Liver Transplantation Is Associated With Poorer Outcomes. | 2018 | Transplantation | pmid:29315140 |
| Naniwa T et al. | Long-term efficacy and safety of add-on tacrolimus for persistent, active rheumatoid arthritis despite treatment with methotrexate and tumor necrosis factor inhibitors. | 2018 | Int J Rheum Dis | pmid:29314738 |
| Li YM et al. | Soluble Tim-3 and Gal-9 are associated with renal allograft dysfunction in kidney transplant recipients: A cross-sectional study. | 2018 | Int. Immunopharmacol. | pmid:29310109 |