tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (2)
- Am. J. Physiol. Renal Physiol. (1)
- Drug Metab. Dispos. (1)
- Others (1)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Al Taii H et al. | The use of tacrolimus in refractory autoimmune hepatitis in children and adults: a single center experience. | 2017 | Scand. J. Gastroenterol. | pmid:27633047 |
| Choi Y et al. | A pharmacogenomic study on the pharmacokinetics of tacrolimus in healthy subjects using the DMET Plus platform. | 2017 | Pharmacogenomics J. | pmid:26882121 |
| Rummo OO et al. | ADHERE: randomized controlled trial comparing renal function in de novo kidney transplant recipients receiving prolonged-release tacrolimus plus mycophenolate mofetil or sirolimus. | 2017 | Transpl. Int. | pmid:27754567 |
| Hou X et al. | Overexpression of Fibulin-5 attenuates burn-induced inflammation via TRPV1/CGRP pathway. | 2017 | Exp. Cell Res. | pmid:28602628 |
| Shahidi M | Thrombosis and von Willebrand Factor. | 2017 | Adv. Exp. Med. Biol. | pmid:27628010 |
| Trasi NS et al. | Evaluation of the Crystallization Tendency of Commercially Available Amorphous Tacrolimus Formulations Exposed to Different Stress Conditions. | 2017 | Pharm. Res. | pmid:28687987 |
| Mourad G et al. | Incidence of Posttransplantation Diabetes Mellitus in De Novo Kidney Transplant Recipients Receiving Prolonged-Release Tacrolimus-Based Immunosuppression With 2 Different Corticosteroid Minimization Strategies: ADVANCE, A Randomized Controlled Trial. | 2017 | Transplantation | pmid:27547871 |
| Tang J et al. | Application of Machine-Learning Models to Predict Tacrolimus Stable Dose in Renal Transplant Recipients. | 2017 | Sci Rep | pmid:28176850 |
| Jin SE et al. | Evaluation of Drug Sorption to PVC- and Non-PVC-based Tubes in Administration Sets Using a Pump. | 2017 | J Vis Exp | pmid:28362410 |
| Eshraghian A et al. | Post-transplant lymphoproliferative disorder after liver transplantation: Incidence, long-term survival and impact of serum tacrolimus level. | 2017 | World J. Gastroenterol. | pmid:28275302 |
| Monaghan P et al. | The antimalarial action of FK506 and rapamycin: evidence for a direct effect on FK506-binding protein PfFKBP35. | 2017 | Parasitology | pmid:28274284 |
| Jackson MF et al. | Osteoclast precursors do not express CD68: results from CD68 promoter-driven RANK transgenic mice. | 2017 | FEBS Lett. | pmid:28173622 |
| Mekaj AY et al. | Effects of hyaluronic acid and tacrolimus on the prevention of perineural scar formation and on nerve regeneration after sciatic nerve repair in a rabbit model. | 2017 | Eur J Trauma Emerg Surg | pmid:27194249 |
| Jessop S et al. | Drugs for discoid lupus erythematosus. | 2017 | Cochrane Database Syst Rev | pmid:28476075 |
| Kirresh T et al. | Development and validation of a liquid chromatography-mass spectrometric assay for simultaneous determination of tacrolimus and 13-O-desmethyl tacrolimus in rat kidney tissue. | 2017 | J Pharm Biomed Anal | pmid:28063333 |
| Qiao M et al. | The Natural Course of Atopic Dermatitis and the Association with Asthma. | 2017 | Inflammation | pmid:28063089 |
| Ianiri G et al. | FKBP12-Dependent Inhibition of Calcineurin Mediates Immunosuppressive Antifungal Drug Action in . | 2017 | MBio | pmid:29066552 |
| Knops N et al. | Tacrolimus dose requirements in paediatric renal allograft recipients are characterized by a biphasic course determined by age and bone maturation. | 2017 | Br J Clin Pharmacol | pmid:27966227 |
| Rivosecchi RM et al. | Effects of Isavuconazole on the Plasma Concentrations of Tacrolimus among Solid-Organ Transplant Patients. | 2017 | Antimicrob. Agents Chemother. | pmid:28674051 |
| Colucci S et al. | The immunophilin FKBP12 inhibits hepcidin expression by binding the BMP type I receptor ALK2 in hepatocytes. | 2017 | Blood | pmid:28864813 |