tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (2)
- Am. J. Physiol. Renal Physiol. (1)
- Drug Metab. Dispos. (1)
- Others (1)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| pmid: | ||||
| Hersperger R et al. | Preparation and immunosuppressive activity of 32-(O)-acylated and 32-(O)-thioacylated analogues of ascomycin. | 1999 | Bioorg. Med. Chem. Lett. | pmid:10021934 |
| Praghakaran K et al. | Rational management of posttransplant lymphoproliferative disorder in pediatric recipients. | 1999 | J. Pediatr. Surg. | pmid:10022154 |
| Reynolds PD et al. | Glucocorticoid resistance in the squirrel monkey is associated with overexpression of the immunophilin FKBP51. | 1999 | J. Clin. Endocrinol. Metab. | pmid:10022435 |
| Powers JF et al. | Discordant effects of rapamycin on proliferation and p70S6 kinase phosphorylation in normal and neoplastic rat chromaffin cells. | 1999 | Neurosci. Lett. | pmid:10025577 |
| Scholz C et al. | R73A and H144Q mutants of the yeast mitochondrial cyclophilin Cpr3 exhibit a low prolyl isomerase activity in both peptide and protein-folding assays. | 1999 | FEBS Lett. | pmid:10025965 |
| Clemann N and Bechter R | Effects of rapamycin and FK 506 on rat Sertoli cells in vitro. | 1998 | Adv. Exp. Med. Biol. | pmid:10026935 |
| Atta MG et al. | Tyrosine kinase inhibitors and immunosuppressants perturb the myo-inositol but not the betaine cotransporter in isotonic and hypertonic MDCK cells. | 1999 | Kidney Int. | pmid:10027932 |
| McDiarmid SV et al. | Factors affecting growth after pediatric liver transplantation. | 1999 | Transplantation | pmid:10030286 |
| Shapiro R et al. | A prospective, randomized trial of tacrolimus/prednisone versus tacrolimus/prednisone/mycophenolate mofetil in renal transplant recipients. | 1999 | Transplantation | pmid:10030287 |
| Dell'Antonio G and Randhawa PS | "Striped" pattern of medullary ray fibrosis in allograft biopsies from kidney transplant recipients maintained on tacrolimus. | 1999 | Transplantation | pmid:10030300 |
| Vyas S et al. | Outcome of twin pregnancy in a renal transplant recipient treated with tacrolimus. | 1999 | Transplantation | pmid:10030303 |
| Johnson CE et al. | Stability of tacrolimus with morphine sulfate, hydromorphone hydrochloride, and ceftazidime during simulated intravenous coadministration. | 1999 | Am J Health Syst Pharm | pmid:10030533 |
| Dolinski KJ and Heitman J | Hmo1p, a high mobility group 1/2 homolog, genetically and physically interacts with the yeast FKBP12 prolyl isomerase. | 1999 | Genetics | pmid:10049913 |
| Regazzi MB et al. | Clinical pharmacokinetics of tacrolimus in heart transplant recipients. | 1999 | Ther Drug Monit | pmid:10051048 |
| Zucker K et al. | Evidence that tacrolimus augments the bioavailability of mycophenolate mofetil through the inhibition of mycophenolic acid glucuronidation. | 1999 | Ther Drug Monit | pmid:10051052 |
| Chen HY et al. | Prediction of tacrolimus blood levels by using the neural network with genetic algorithm in liver transplantation patients. | 1999 | Ther Drug Monit | pmid:10051054 |
| Yamaguchi Y et al. | Peroxynitrite formation during rat hepatic allograft rejection. | 1999 | Hepatology | pmid:10051479 |
| Clardy J | Borrowing to make ends meet. | 1999 | Proc. Natl. Acad. Sci. U.S.A. | pmid:10051553 |
| Briesewitz R et al. | Affinity modulation of small-molecule ligands by borrowing endogenous protein surfaces. | 1999 | Proc. Natl. Acad. Sci. U.S.A. | pmid:10051576 |