tacrolimus

Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.

Cross Reference

Introduction

To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with tacrolimus?

tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with tacrolimus

MeSH term MeSH ID Detail
Respiratory Tract Neoplasms D012142 2 associated lipids
Respiratory Insufficiency D012131 10 associated lipids
Respiration Disorders D012120 5 associated lipids
Reflex Sympathetic Dystrophy D012019 4 associated lipids
Red-Cell Aplasia, Pure D012010 4 associated lipids
Rectal Fistula D012003 2 associated lipids
Rectal Diseases D012002 1 associated lipids
Purpura, Thrombotic Thrombocytopenic D011697 6 associated lipids
Pulmonary Veno-Occlusive Disease D011668 1 associated lipids
Pterygium D011625 3 associated lipids
Psychoses, Substance-Induced D011605 7 associated lipids
Psoriasis D011565 47 associated lipids
Pseudomonas Infections D011552 25 associated lipids
Pseudohypoaldosteronism D011546 1 associated lipids
Pruritus Vulvae D011539 1 associated lipids
Pruritus Ani D011538 2 associated lipids
Prurigo D011536 4 associated lipids
Proteinuria D011507 30 associated lipids
Priapism D011317 1 associated lipids
Pregnancy Complications D011248 19 associated lipids
Precancerous Conditions D011230 48 associated lipids
Poxviridae Infections D011213 1 associated lipids
Postoperative Complications D011183 5 associated lipids
Polyneuropathies D011115 3 associated lipids
Pityriasis D010915 3 associated lipids
Pharyngitis D010612 2 associated lipids
Peritoneal Neoplasms D010534 16 associated lipids
Peripheral Nervous System Diseases D010523 33 associated lipids
Periodontal Pocket D010514 9 associated lipids
Pericarditis D010493 6 associated lipids
Perceptual Disorders D010468 3 associated lipids
Peptic Ulcer Perforation D010439 3 associated lipids
Peptic Ulcer D010437 19 associated lipids
Pemphigus D010392 3 associated lipids
Pemphigoid, Bullous D010391 8 associated lipids
Pemphigoid, Benign Mucous Membrane D010390 4 associated lipids
Parotitis D010309 4 associated lipids
Paronychia D010304 3 associated lipids
Parkinson Disease D010300 53 associated lipids
Paresis D010291 2 associated lipids
Paraproteinemias D010265 2 associated lipids
Pancytopenia D010198 6 associated lipids
Pancreatic Fistula D010185 2 associated lipids
Pain, Intractable D010148 4 associated lipids
Pain D010146 64 associated lipids
Ovarian Cysts D010048 4 associated lipids
Osteoporosis D010024 12 associated lipids
Osteonecrosis D010020 5 associated lipids
Osteomalacia D010018 5 associated lipids
Osteochondrodysplasias D010009 3 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with tacrolimus

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with tacrolimus?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with tacrolimus?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with tacrolimus?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with tacrolimus?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with tacrolimus?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with tacrolimus

Download all related citations
Per page 10 20 50 100 | Total 15051
Authors Title Published Journal PubMed Link
Gómez-Bravo MA et al. Influence of donor liver CYP3A4*20 loss-of-function genotype on tacrolimus pharmacokinetics in transplanted patients. 2018 Pharmacogenet. Genomics pmid:29256966
Motta A et al. Immunohistopathological characterization and the impact of topical immunomodulatory therapy in oral chronic graft-versus-host disease: A pilot study. 2018 Oral Dis pmid:29197137
Leiskau C et al. Side effects and efficacy of renal sparing immunosuppression in pediatric liver transplantation-A single center matched cohort study. 2018 Pediatr Transplant pmid:29729061
Bae SC and Lee YH Comparative efficacy and tolerability of monotherapy with leflunomide or tacrolimus for the treatment of rheumatoid arthritis: a Bayesian network meta-analysis of randomized controlled trials. 2018 Clin. Rheumatol. pmid:28967035
Al-Lawati H et al. Nanomedicine for immunosuppressive therapy: achievements in pre-clinical and clinical research. 2018 Expert Opin Drug Deliv pmid:29261332
Park CS et al. Tetrahydrocurcumin Ameliorates Tacrolimus-Induced Nephrotoxicity Via Inhibiting Apoptosis. 2018 Transplant. Proc. pmid:30401411
Htun YY et al. CYP3A5*3 Genetic Polymorphism and Tacrolimus Concentration in Myanmar Renal Transplant Patients. 2018 Transplant. Proc. pmid:29731062
Mücke VT et al. Low Serum Levels of (Dihydro-)Ceramides Reflect Liver Graft Dysfunction in a Real-World Cohort of Patients Post Liver Transplantation. 2018 Int J Mol Sci pmid:29587453
Davidson HE Shifting Paradigms in Caring for Older Adults. 2018 Consult Pharm pmid:29789044
Pircher C et al. A rare case of Epstein-Barr virus-associated hepatosplenic smooth muscle tumors after kidney transplantation. 2018 Transpl Infect Dis pmid:29427352