| MeSH term | MeSH ID | Detail |
|---|---|---|
| Heart Failure | D006333 | 36 associated lipids |
| Angioedema | D000799 | 6 associated lipids |
| Fractures, Spontaneous | D005598 | 4 associated lipids |
| Hydronephrosis | D006869 | 4 associated lipids |
| Trypanosomiasis | D014352 | 5 associated lipids |
| Alopecia | D000505 | 14 associated lipids |
| Liver Diseases | D008107 | 31 associated lipids |
| Corneal Diseases | D003316 | 13 associated lipids |
| Testicular Diseases | D013733 | 15 associated lipids |
| Facial Dermatoses | D005148 | 7 associated lipids |
tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (2)
- Am. J. Physiol. Renal Physiol. (1)
- Drug Metab. Dispos. (1)
- Others (1)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Shin BH et al. | Regulation of anti-HLA antibody-dependent natural killer cell activation by immunosuppressive agents. | 2014 | Transplantation | pmid:24342979 |
| Siddiqui A et al. | Chemometric methods for the quantification of crystalline tacrolimus in solid dispersion by powder X-ray diffractrometry. | 2014 | J Pharm Sci | pmid:24585357 |
| Shivaswamy V et al. | Tacrolimus and sirolimus have distinct effects on insulin signaling in male and female rats. | 2014 | Transl Res | pmid:24361102 |
| Uesugi S et al. | Calcineurin inhibitors suppress the high-temperature stress sensitivity of the yeast ubiquitin ligase Rsp5 mutant: a new method of screening for calcineurin inhibitors. | 2014 | FEMS Yeast Res. | pmid:25035868 |
| Goldberg NR et al. | Success with single-agent immunosuppression for multifocal choroidopathies. | 2014 | Am. J. Ophthalmol. | pmid:25194229 |
| Suarez-Kurtz G et al. | Pharmacogenomic implications of population admixture: Brazil as a model case. | 2014 | Pharmacogenomics | pmid:24444410 |
| Ducroux E et al. | Hidradenitis suppurativa after renal transplantation: complete remission after switching from oral cyclosporine to oral tacrolimus. | 2014 | J. Am. Acad. Dermatol. | pmid:25437996 |
| Hancock WW | Effects of histone deacetylase inhibitors on alloresponses. | 2014 | Lancet Oncol. | pmid:24295573 |
| Taguchi K et al. | False tacrolimus concentrations measured by antibody-conjugated magnetic immunoassay in liver transplant patient: 2 case reports and literature review. | 2014 | Exp Clin Transplant | pmid:24206050 |
| Trotter JF and Lizardo-Sanchez L | Everolimus in liver transplantation. | 2014 | Curr Opin Organ Transplant | pmid:25254569 |
| RodrÃguez-Serrano M et al. | Does the calcineurin inhibitor have influence on cytomegalovirus infection in heart transplantation? | 2014 | Clin Transplant | pmid:24325305 |
| Sæves I et al. | Tacrolimus exposure and mycophenolate pharmacokinetics and pharmacodynamics early after liver transplantation. | 2014 | Ther Drug Monit | pmid:24081206 |
| Ghanem RC et al. | Tacrolimus for the treatment of subepithelial infiltrates resistant to topical steroids after adenoviral keratoconjunctivitis. | 2014 | Cornea | pmid:25188789 |
| Spasovski G and Masin-Spasovska J | How to improve the survival of the kidney transplant - is it only the pharmaceutical management? | 2014 | Expert Opin Pharmacother | pmid:24617949 |
| Kim JS et al. | Effects of FK-506 and CTLA4--Ig on nerve allografts in mice. | 2014 | J Plast Reconstr Aesthet Surg | pmid:24120418 |
| Purani JM and Purani HJ | Treatment of geographic tongue with topical tacrolimus. | 2014 | BMJ Case Rep | pmid:25085945 |
| Kornblit B et al. | A randomized phase II trial of tacrolimus, mycophenolate mofetil and sirolimus after non-myeloablative unrelated donor transplantation. | 2014 | Haematologica | pmid:25085357 |
| Thapa RK and Yoo BK | Evaluation of the effect of tacrolimus-loaded liquid crystalline nanoparticles on psoriasis-like skin inflammation. | 2014 | J Dermatolog Treat | pmid:23210668 |
| Yamazoe K et al. | Efficacy and safety of systemic tacrolimus in high-risk penetrating keratoplasty after graft failure with systemic cyclosporine. | 2014 | Cornea | pmid:25255133 |
| John K et al. | Role of dendritic cells in the context of acute cellular rejection: comparison between tacrolimus- or cyclosporine A-treated heart transplanted recipients. | 2014 | Cytometry B Clin Cytom | pmid:24668729 |
| Okamoto T et al. | Clinically mild encephalitis/encephalopathy with a reversible splenial lesion associated with febrile urinary tract infection. | 2014 | Eur. J. Pediatr. | pmid:24221606 |
| Steinebrunner N et al. | Reduced residual gene expression of nuclear factor of activated T cells-regulated genes correlates with the risk of cytomegalovirus infection after liver transplantation. | 2014 | Transpl Infect Dis | pmid:24666466 |
| Rahman Z et al. | Near-infrared and fourier transform infrared chemometric methods for the quantification of crystalline tacrolimus from sustained-release amorphous solid dispersion. | 2014 | J Pharm Sci | pmid:24931728 |
| Kim SH et al. | Expression, purification and characterization of soluble recombinant peptidyl-prolyl cis/trans isomerase from Vibrio anguillarum. | 2014 | Protein Expr. Purif. | pmid:24931498 |
| Cutler C et al. | Tacrolimus/sirolimus vs tacrolimus/methotrexate as GVHD prophylaxis after matched, related donor allogeneic HCT. | 2014 | Blood | pmid:24982504 |
| Tran D et al. | Conversion from twice-daily to once-daily extended-release tacrolimus in renal transplant recipients: 2-year results and review of the literature. | 2014 | Exp Clin Transplant | pmid:24844288 |
| Kahvecioglu S et al. | Effects of calcineurin inhibitors on paraoxonase and arylesterase activity after a kidney transplant. | 2014 | Exp Clin Transplant | pmid:24447269 |
| Kalkan G et al. | An alternative treatment model: the combination therapy of narrow band ultraviolet B phototherapy and tacrolimus ointment 0.1% in biphasic amyloidosis. | 2014 | J Pak Med Assoc | pmid:25272550 |
| Hashi S et al. | Assessment of four methodologies (microparticle enzyme immunoassay, chemiluminescent enzyme immunoassay, affinity column-mediated immunoassay, and flow injection assay-tandem mass spectrometry) for measuring tacrolimus blood concentration in Japanese liver transplant recipients. | 2014 | Transplant. Proc. | pmid:24767342 |
| Uemoto S et al. | Safety and efficacy of once-daily modified-release tacrolimus in liver transplant recipients: a multicenter postmarketing surveillance in Japan. | 2014 | Transplant. Proc. | pmid:24767340 |
| Borda B et al. | Side effects of the calcineurin inhibitor, such as new-onset diabetes after kidney transplantation. | 2014 | Acta Physiol Hung | pmid:25183511 |
| Heilman RL et al. | Delayed allograft inflammation following alemtuzumab induction for kidney transplantation. | 2013 Sep-Oct | Clin Transplant | pmid:23924146 |
| Benoit S and Hamm H | Psoriasis from a prosthesis: unusual Koebner phenomenon in a girl with autoamputation of the leg. | 2013 Sep-Oct | Pediatr Dermatol | pmid:23360396 |
| Zahdi MR et al. | Erosive pustular dermatosis of the scalp successfully treated with oral prednisone and topical tacrolimus. | 2013 Sep-Oct | An Bras Dermatol | pmid:24173187 |
| Riva N et al. | [Pharmacovigilance of calcineurin inhibitor in peidatric kidney and liver transplantation]. | 2013 Nov-Dec | Farm Hosp | pmid:24256007 |
| Brodrick B et al. | Influence of treatments on prognosis for vulvar lichen sclerosus: facts and controversies. | 2013 Nov-Dec | Clin. Dermatol. | pmid:24160287 |
| Bloom RD et al. | A randomized, crossover pharmacokinetic study comparing generic tacrolimus vs. the reference formulation in subpopulations of kidney transplant patients. | 2013 Nov-Dec | Clin Transplant | pmid:24118450 |
| Labirua-Iturburu A et al. | Calcineurin inhibitors in a cohort of patients with antisynthetase-associated interstitial lung disease. | 2013 May-Jun | Clin. Exp. Rheumatol. | pmid:23465087 |
| Chen SY et al. | Individualization of tacrolimus dosage basing on cytochrome P450 3A5 polymorphism--a prospective, randomized, controlled study. | 2013 May-Jun | Clin Transplant | pmid:23432535 |
| Ramirez CB et al. | Completely steroid-free immunosuppression in liver transplantation: a randomized study. | 2013 May-Jun | Clin Transplant | pmid:23621629 |
| Krishna N et al. | Tacrolimus-induced paranoid delusions and fugue-like state. | 2013 May-Jun | Gen Hosp Psychiatry | pmid:22959421 |
| He L et al. | Treatment of idiopathic membranous nephropathy with combination of low-dose tacrolimus and corticosteroids. | 2013 May-Jun | J. Nephrol. | pmid:22956434 |
| Kanzelmeyer NK et al. | Correlations with six-month protocol biopsy findings in pediatric transplant recipients on low- and regular-dose CNI regimens. | 2013 Mar-Apr | Clin Transplant | pmid:23414365 |
| Tiwari R et al. | Enhancements in healthcare information technology systems: customizing vendor-supplied clinical decision support for a high-risk patient population. | 2013 Mar-Apr | J Am Med Inform Assoc | pmid:22813760 |
| Albekairy A et al. | Cytochrome P450 3A4FNx011B as pharmacogenomic predictor of tacrolimus pharmacokinetics and clinical outcome in the liver transplant recipients. | 2013 Mar-Apr | Saudi J Gastroenterol | pmid:23481136 |
| LaMattina JC et al. | Native kidney function following liver transplantation using calcineurin inhibitors: single-center analysis with 20 years of follow-up. | 2013 Mar-Apr | Clin Transplant | pmid:23294013 |
| Alfson ED et al. | Lysis of catatonic withdrawal by propofol in a bone-marrow transplant recipient with adenovirus limbic encephalitis. | 2013 Mar-Apr | Psychosomatics | pmid:22705183 |
| Yoshida EM et al. | Canadian national retrospective chart review comparing the long term effect of cyclosporine vs. tacrolimus on clinical outcomes in patients with post-liver transplantation hepatitis C virus infection. | 2013 Mar-Apr | Ann Hepatol | pmid:23396740 |
| Castillo G et al. | [Acute cellular rejection in a liver transplantation patient due to changing the brand of a generic immunosuppressant]. | 2013 Jul-Sep | Rev Gastroenterol Mex | pmid:23866966 |
| Bechstein WO et al. | A comparative, randomized trial of concentration-controlled sirolimus combined with reduced-dose tacrolimus or standard-dose tacrolimus in renal allograft recipients. | 2013 Jul-Aug | Transplant. Proc. | pmid:23953523 |
| Zhao YJ et al. | Late, severe, noninfectious diarrhea after renal transplantation: high-risk factors, therapy, and prognosis. | 2013 Jul-Aug | Transplant. Proc. | pmid:23953533 |
| Weiler N et al. | Tacrolimus effects and side effects after liver transplantation: is there a difference between immediate and extended release? | 2013 Jul-Aug | Transplant. Proc. | pmid:23953543 |
| Stringa P et al. | Ischemic preconditioning and tacrolimus pretreatment as strategies to attenuate intestinal ischemia-reperfusion injury in mice. | 2013 Jul-Aug | Transplant. Proc. | pmid:23953566 |
| Tachibana A et al. | Repopulation of the immunosuppressed retrorsine-treated infant rat liver with human hepatocytes. | 2013 Jul-Aug | Xenotransplantation | pmid:23683097 |
| Favi E et al. | Tacrolimus plus mycophenolate mofetil vs. cyclosporine plus everolimus in deceased donor kidney transplant recipients: three-yr results of a single-center prospective clinical trial. | 2013 Jul-Aug | Clin Transplant | pmid:23710603 |
| Eberlin M et al. | Increased medication compliance of liver transplant patients switched from a twice-daily to a once-daily tacrolimus-based immunosuppressive regimen. | 2013 Jul-Aug | Transplant. Proc. | pmid:23726723 |
| Satyanarayan HS et al. | Efficacy and tolerability of combined treatment with NB-UVB and topical tacrolimus versus NB-UVB alone in patients with vitiligo vulgaris: a randomized intra-individual open comparative trial. | 2013 Jul-Aug | Indian J Dermatol Venereol Leprol | pmid:23760325 |
| Babalola O and Strober BE | Treatment of atopic dermatitis in pregnancy. | 2013 Jul-Aug | Dermatol Ther | pmid:23914886 |
| Conti R et al. | Jessner-Kanof disease: two effective and sure therapeutic options. | 2013 Jul-Aug | Dermatol Ther | pmid:23914897 |
| Chakkera HA et al. | Genetic differences in Native Americans and tacrolimus dosing after kidney transplantation. | 2013 Jan-Feb | Transplant. Proc. | pmid:23375287 |
| Tian Ch et al. | B- and T-lymphocyte attenuator/herpes virus entry mediator as early indicators for acute rejection following kidney transplantation. | 2013 Jan-Feb | Transplant. Proc. | pmid:23375291 |
| Yao B et al. | The incidence of posttransplantation diabetes mellitus during follow-up in kidney transplant recipients and relationship to Fok1 vitamin D receptor polymorphism. | 2013 Jan-Feb | Transplant. Proc. | pmid:23375298 |
| Miyazaki T et al. | Two case reports of successful withdrawal of mycofenolate mofetil after living donor lobar lung transplantation. | 2013 Jan-Feb | Transplant. Proc. | pmid:23375323 |
| Chang HY et al. | Long-term follow-up of arrhythmia characteristics and clinical outcomes in heart transplant patients. | 2013 Jan-Feb | Transplant. Proc. | pmid:23375324 |
| Al Nahdi N et al. | First successful treatment of post-liver transplant hepatitis C fibrosing cholestatic hepatitis with boceprevir, peginterferon and ribavirin in a pre-transplant null responder. | 2013 Jan-Feb | Ann Hepatol | pmid:23293209 |
| Seco-Melantuche R et al. | [Incidence of drug-induced thrombocytopenia in hospitalized patients]. | 2013 Jan-Feb | Farm Hosp | pmid:23461497 |
| Rao V et al. | A non-induction renal sparing approach after liver transplantation: high dose mycophenolate mofetil with delayed, low-dose tacrolimus. | 2013 Jan-Feb | Transplant. Proc. | pmid:23267806 |
| Langone A et al. | Does reduction in mycophenolic acid dose compromise efficacy regardless of tacrolimus exposure level? An analysis of prospective data from the Mycophenolic Renal Transplant (MORE) Registry. | 2013 Jan-Feb | Clin Transplant | pmid:22861144 |
| Shiba H et al. | Switching from tacrolimus to cyclosporine A to prevent primary biliary cirrhosis recurrence after living-donor liver transplantation. | 2013 Apr-Jun | Int Surg | pmid:23701152 |
| Adamu B et al. | New-onset diabetes after renal transplantation: a case series as seen in a Nigerian kidney transplant population. | 2013 Apr-Jun | Niger J Clin Pract | pmid:23563475 |
| Cangemi G et al. | Comparison of antibody-conjugated magnetic immunoassay and liquid chromatography-tandem mass spectrometry for the measurement of cyclosporine and tacrolimus in whole blood. | 2013 Apr-Jun | Int J Immunopathol Pharmacol | pmid:23755756 |
| Armenti VT et al. | Breastfeeding and tacrolimus: is it a reasonable approach? | 2013 | Expert Rev Clin Immunol | pmid:23899232 |
| Gómez-Bravo MA et al. | Impact of donor and recipient CYP3A5 and ABCB1 genetic polymorphisms on tacrolimus dosage requirements and rejection in Caucasian Spanish liver transplant patients. | 2013 | J Clin Pharmacol | pmid:23900887 |
| Neto P et al. | De novo tacrolimus- associated hemolytic uremic syndrome after renal transplantation - case report. | 2013 | Nefrologia | pmid:23364650 |
| Park JH et al. | The effectiveness of early treatment in segmental vitiligo: retrospective study according to disease duration. | 2013 | Photodermatol Photoimmunol Photomed | pmid:23458396 |
| Zuo XC et al. | Effects of CYP3A4 and CYP3A5 polymorphisms on tacrolimus pharmacokinetics in Chinese adult renal transplant recipients: a population pharmacokinetic analysis. | 2013 | Pharmacogenet. Genomics | pmid:23459029 |
| Verma S et al. | Preradial myxedema in a euthyroid male: A distinct rarity. | 2013 | Dermatol. Online J. | pmid:24021369 |
| Yosipovitch G et al. | A comparative study of clinical characteristics, work-up, treatment, and association to malignancy in dermatomyositis between two tertiary skin centers in the USA and Singapore. | 2013 | Int. J. Dermatol. | pmid:22835263 |
| Hirsch HH et al. | Polyomavirus BK replication in de novo kidney transplant patients receiving tacrolimus or cyclosporine: a prospective, randomized, multicenter study. | 2013 | Am. J. Transplant. | pmid:23137180 |
| Lamoth F et al. | In vitro activity of calcineurin and heat shock protein 90 Inhibitors against Aspergillus fumigatus azole- and echinocandin-resistant strains. | 2013 | Antimicrob. Agents Chemother. | pmid:23165466 |
| Zhu Q et al. | Pluronic F127-modified liposome-containing tacrolimus-cyclodextrin inclusion complexes: improved solubility, cellular uptake and intestinal penetration. | 2013 | J. Pharm. Pharmacol. | pmid:23837579 |
| Augusto JF et al. | Long-term maintenance immunosuppressive regimen with tacrolimus monotherapy. | 2013 | Ann. Transplant. | pmid:23872516 |
| Sapoznikov D et al. | Heart rate response to blood pressure variations: sympathetic activation versus baroreflex response in patients with end-stage renal disease. | 2013 | PLoS ONE | pmid:24124623 |
| RodrÃguez-Perálvarez M et al. | Early tacrolimus exposure after liver transplantation: relationship with moderate/severe acute rejection and long-term outcome. | 2013 | J. Hepatol. | pmid:23023010 |
| Ciftci HS et al. | Effect of MDR1 polymorphisms on the blood concentrations of tacrolimus in Turkish renal transplant patients. | 2013 | Transplant. Proc. | pmid:23622581 |
| Magalhaes OA et al. | Topical 0.03% tacrolimus preventing rejection in high-risk corneal transplantation: a cohort study. | 2013 | Br J Ophthalmol | pmid:24008822 |
| Quaglia M et al. | Severe acute nephrotoxicity in a kidney transplant patient despite low tacrolimus levels: a possible interaction between donor and recipient genetic polymorphisms. | 2013 | J Clin Pharm Ther | pmid:23574377 |
| Wang R et al. | Systemic lupus erythematosus associated with Moyamoya syndrome: a case report and literature review. | 2013 | Lupus | pmid:23574743 |
| Miyoshi J et al. | Mucosal healing with oral tacrolimus is associated with favorable medium- and long-term prognosis in steroid-refractory/dependent ulcerative colitis patients. | 2013 | J Crohns Colitis | pmid:23680174 |
| Xia M et al. | Enhanced FK506 production in Streptomyces tsukubaensis by rational feeding strategies based on comparative metabolic profiling analysis. | 2013 | Biotechnol. Bioeng. | pmid:23682004 |
| Cristelli MP et al. | Safety profile comparing azathioprine and mycophenolate in kidney transplant recipients receiving tacrolimus and corticosteroids. | 2013 | Transpl Infect Dis | pmid:23701592 |
| Siegfried EC et al. | Topical calcineurin inhibitors and lymphoma risk: evidence update with implications for daily practice. | 2013 | Am J Clin Dermatol | pmid:23703374 |
| Zhou X et al. | A genome-wide screening of potential target genes to enhance the antifungal activity of micafungin in Schizosaccharomyces pombe. | 2013 | PLoS ONE | pmid:23738021 |
| Chitnis SD et al. | Concentration of tacrolimus and major metabolites in kidney transplant recipients as a function of diabetes mellitus and cytochrome P450 3A gene polymorphism. | 2013 | Xenobiotica | pmid:23278282 |
| Bunnapradist S et al. | Conversion from twice-daily tacrolimus to once-daily extended release tacrolimus (LCPT): the phase III randomized MELT trial. | 2013 | Am. J. Transplant. | pmid:23279614 |
| Böer TM et al. | Correlation of thermal analysis and pyrolysis coupled to GC-MS in the characterization of tacrolimus. | 2013 | J Pharm Biomed Anal | pmid:22361660 |
| Bootun R | Effects of immunosuppressive therapy on wound healing. | 2013 | Int Wound J | pmid:22364410 |
| Tanaka Y et al. | [Effect of tacrolimus on the pharmacokinetics and glucuronidation of SN-38, an active metabolite of irinotecan]. | 2013 | Yakugaku Zasshi | pmid:23328499 |
| Wong R and Lin AN | Efficacy of topical calcineurin inhibitors in vitiligo. | 2013 | Int. J. Dermatol. | pmid:23331250 |
| Mori T et al. | Effective treatment of a 13-year-old boy with steroid-dependent ocular myasthenia gravis using tacrolimus. | 2013 | Brain Dev. | pmid:22840813 |