| MeSH term | MeSH ID | Detail |
|---|---|---|
| Stomach Ulcer | D013276 | 75 associated lipids |
| Alzheimer Disease | D000544 | 76 associated lipids |
| Diabetes Mellitus, Experimental | D003921 | 85 associated lipids |
| Atherosclerosis | D050197 | 85 associated lipids |
| Arteriosclerosis | D001161 | 86 associated lipids |
| Seizures | D012640 | 87 associated lipids |
| Diabetes Mellitus, Type 2 | D003924 | 87 associated lipids |
| Brain Ischemia | D002545 | 89 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Hypercholesterolemia | D006937 | 91 associated lipids |
tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (2)
- Am. J. Physiol. Renal Physiol. (1)
- Drug Metab. Dispos. (1)
- Others (1)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
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| Wu SW et al. | Conversion to prolonged release tacrolimus formulation in stable kidney transplant recipients. | 2013 | Swiss Med Wkly | pmid:23986367 |
| Yagi Y et al. | Tacrolimus monotherapy: a promising option for ocular myasthenia gravis. | 2013 | Eur. Neurol. | pmid:23549260 |
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| Picard N | The pharmacokinetic interaction between mycophenolic acid and cyclosporine revisited: a commentary on "Mycophenolic acid glucuronide is transported by multidrug resistance-associated protein 2 and this transport is not inhibited by cyclosporine, tacrolimus or sirolimus". | 2013 | Xenobiotica | pmid:23339626 |
| Tanaka E and Yamanaka H | [DMARDs (disease-modifying antirheumatic drugs)]. | 2013 | Nippon Rinsho | pmid:23961667 |
| de Jonge H and Kuypers DR | Response to "pretransplantation pharmacokinetic assessments to predict posttransplantation dosing requirements in renal transplant recipients: what is known?". | 2013 | Clin. Pharmacol. Ther. | pmid:23340478 |
| Risseeuw MD et al. | A "clickable" MTX reagent as a practical tool for profiling small-molecule-intracellular target interactions via MASPIT. | 2013 | ChemMedChem | pmid:23341183 |
| Ren H et al. | Tacrolimus versus cyclophosphamide in steroid-dependent or steroid-resistant focal segmental glomerulosclerosis: a randomized controlled trial. | 2013 | Am. J. Nephrol. | pmid:23343906 |
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| Cardet JC and Boyce JA | Addition of mycophenolate mofetil to tacrolimus is associated with decreases in food-specific IgE levels in a pediatric patient with liver transplantation-associated food allergy. | 2013 | J Allergy Clin Immunol Pract | pmid:24229832 |
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| Verhave JC et al. | Living kidney transplantation in adult patients with atypical haemolytic uraemic syndrome. | 2013 | Neth J Med | pmid:24038559 |
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| Muthukumar T et al. | HIV-infected kidney graft recipients managed with an early corticosteroid withdrawal protocol: clinical outcomes and messenger RNA profiles. | 2013 | Transplantation | pmid:23503504 |
| Nakamura T et al. | Co-stimulation with bone morphogenetic protein-9 and FK506 induces remarkable osteoblastic differentiation in rat dedifferentiated fat cells. | 2013 | Biochem. Biophys. Res. Commun. | pmid:24064349 |
| Manojlovic Z et al. | Tacrolimus (FK506) prevents early stages of ethanol induced hepatic fibrosis by targeting LARP6 dependent mechanism of collagen synthesis. | 2013 | PLoS ONE | pmid:23755290 |
| Wu X et al. | Design and physicochemical characterization of advanced spray-dried tacrolimus multifunctional particles for inhalation. | 2013 | Drug Des Devel Ther | pmid:23403805 |
| van Gorp S et al. | Amelioration of motor/sensory dysfunction and spasticity in a rat model of acute lumbar spinal cord injury by human neural stem cell transplantation. | 2013 | Stem Cell Res Ther | pmid:23710605 |
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| Mok CC et al. | Combined low-dose mycophenolate mofetil and tacrolimus for lupus nephritis with suboptimal response to standard therapy: a 12-month prospective study. | 2013 | Lupus | pmid:23995863 |
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| Choi JY and Kwon OJ | Post-transplant diabetes mellitus: is it associated with poor allograft outcomes in renal transplants? | 2013 | Transplant. Proc. | pmid:24156999 |
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| Kang KY et al. | Tacrolimus treatment increases bone formation in patients with rheumatoid arthritis. | 2013 | Rheumatol. Int. | pmid:22447331 |
| Sato H et al. | Atypical severe central serous chorioretinopathy in a patient with systemic lupus erythematosus improved with a rapid reduction in glucocorticoid. | 2013 | Mod Rheumatol | pmid:22447556 |
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| Lee JT et al. | Calcineurin inhibitors and Clostridium difficile infection in adult lung transplant recipients: the effect of cyclosporine versus tacrolimus. | 2013 | J. Surg. Res. | pmid:23566442 |
| Gerich ME et al. | Tacrolimus salvage in anti-tumor necrosis factor antibody treatment-refractory Crohn's disease. | 2013 | Inflamm. Bowel Dis. | pmid:23518805 |
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| Elens L et al. | The CYP3A4*22 allele affects the predictive value of a pharmacogenetic algorithm predicting tacrolimus predose concentrations. | 2013 | Br J Clin Pharmacol | pmid:23163400 |
| Qin XL et al. | Effect of long-term co-administration of Wuzhi tablet (Schisandra sphenanthera extract) and prednisone on the pharmacokinetics of tacrolimus. | 2013 | Phytomedicine | pmid:23267661 |
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