Naito M et al. |
Reversal of multidrug resistance by an immunosuppressive agent FK-506. |
1992 |
Cancer Chemother. Pharmacol. |
pmid:1370765
|
Yem AW et al. |
The Hsp56 component of steroid receptor complexes binds to immobilized FK506 and shows homology to FKBP-12 and FKBP-13. |
1992 |
J. Biol. Chem. |
pmid:1371107
|
Park ST et al. |
PPIase catalysis by human FK506-binding protein proceeds through a conformational twist mechanism. |
1992 |
J. Biol. Chem. |
pmid:1371117
|
Asako H et al. |
Reduction of leukocyte adherence and emigration by cyclosporine and L683,590 (FK506) in postcapillary venules. |
1992 |
Transplantation |
pmid:1384191
|
Matsuzaki T et al. |
Liver transplantation for diethylnitrosamine-induced hepatocellular carcinoma in rats. |
1992 |
Transplant. Proc. |
pmid:1373547
|
Vincent SH et al. |
In vitro metabolism of FK-506 in rat, rabbit, and human liver microsomes: identification of a major metabolite and of cytochrome P450 3A as the major enzymes responsible for its metabolism. |
1992 |
Arch. Biochem. Biophys. |
pmid:1373595
|
Yamada K et al. |
New morphological changes induced by FK506 in a short period in the rat kidney and the effect of superoxide dismutase and OKY-046 on THEM: the relationship of FK506 nephrotoxicity to lipid peroxidation and change in production of thromboxane A2 in the kidney. |
1992 |
Transpl. Int. |
pmid:14621878
|
Bernstein L and Daviss SR |
Organic anxiety disorder with symptoms of akathisia in a patient treated with the immunosuppressant FK506. |
1992 |
Gen Hosp Psychiatry |
pmid:1376291
|
Hatfield SM et al. |
Rapamycin and FK506 differentially inhibit mast cell cytokine production and cytokine-induced proliferation and act as reciprocal antagonists. |
1992 |
J. Pharmacol. Exp. Ther. |
pmid:1376361
|
Ericzon BG et al. |
The effect of FK506 treatment on pancreaticoduodenal allotransplantation in the primate. |
1992 |
Transplantation |
pmid:1376501
|
Tze WJ et al. |
FK 506--an effective immunosuppressant in achieving long-term functional islet allograft survival in diabetic rats. |
1992 |
Transplant. Proc. |
pmid:1376509
|
Ozawa K et al. |
An appraisal of pediatric liver transplantation from living relatives. Initial clinical experiences in 20 pediatric liver transplantations from living relatives as donors. |
1992 |
Ann. Surg. |
pmid:1280074
|
Akutsu I et al. |
[Inhibitory effects of cyclosporin A and FK-506 on eosinophil chemotactic factor activity in culture supernatants of mononuclear cells from asthmatics]. |
1992 |
Arerugi |
pmid:1280086
|
Bergstrand H and Lundquist B |
Human basophil histamine release is differently affected by inhibitors of calmodulin, diacylglycerol kinase and peptidyl prolyl cis-trans isomerase in a secretagogue specific manner. |
1992 |
Allergy |
pmid:1280915
|
Akutsu I et al. |
[Inhibitory effect of inhaled FK-506 on increased bronchial responsiveness and eosinophil infiltration in the airway mucosa]. |
1992 |
Arerugi |
pmid:1377905
|
Takaori K et al. |
A comparative study on immunosuppressive effects of cyclosporin A and FK 506 on peripheral blood lymphocytes in dogs. |
1992 |
Biotherapy |
pmid:1377926
|
Murthy JN et al. |
Radioreceptor assay for quantifying FK-506 immunosuppressant in whole blood. |
1992 |
Clin. Chem. |
pmid:1377995
|
Lauerma AI et al. |
Inhibition of contact allergy reactions by topical FK506. |
1992 |
Lancet |
pmid:1380111
|
Steiner JP et al. |
High brain densities of the immunophilin FKBP colocalized with calcineurin. |
1992 |
Nature |
pmid:1380130
|
Aperia A et al. |
Calcineurin mediates alpha-adrenergic stimulation of Na+,K(+)-ATPase activity in renal tubule cells. |
1992 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:1380157
|
Ruff VA et al. |
Tissue distribution and cellular localization of hsp56, an FK506-binding protein. Characterization using a highly specific polyclonal antibody. |
1992 |
J. Biol. Chem. |
pmid:1383222
|
Wiederrecht G et al. |
Characterization of high molecular weight FK-506 binding activities reveals a novel FK-506-binding protein as well as a protein complex. |
1992 |
J. Biol. Chem. |
pmid:1383226
|
Morris RE |
Immunopharmacology of new xenobiotic immunosuppressive molecules. |
1992 |
Semin. Nephrol. |
pmid:1384096
|
Jordan ML et al. |
Initial studies with FK506 in renal transplantation. |
1991 Sep-Oct |
Cleve Clin J Med |
pmid:1718631
|
Jusko WJ and D'Ambrosio R |
Monitoring FK 506 concentrations in plasma and whole blood. |
1991 |
Transplant. Proc. |
pmid:1721260
|
Venkataramanan R et al. |
Pharmacokinetics of FK 506 in transplant patients. |
1991 |
Transplant. Proc. |
pmid:1721261
|
Christians U et al. |
High performance liquid chromatography/mass spectrometry of FK 506 and its metabolites in blood, bile, and urine of liver grafted patients. |
1991 |
Transplant. Proc. |
pmid:1721262
|
Beysens AJ et al. |
FK 506: monitoring in plasma or in whole blood? |
1991 |
Transplant. Proc. |
pmid:1721263
|
Grenier FC et al. |
A whole blood FK 506 assay for the IMx analyzer. |
1991 |
Transplant. Proc. |
pmid:1721264
|
Friob MC et al. |
A combined HPLC-ELISA evaluation of FK 506 in transplant patients. |
1991 |
Transplant. Proc. |
pmid:1721265
|
Machida M et al. |
Effect of temperature and hematocrit on plasma concentration of FK 506. |
1991 |
Transplant. Proc. |
pmid:1721266
|
Akselband Y et al. |
Rapamycin inhibits spontaneous and fibroblast growth factor beta-stimulated proliferation of endothelial cells and fibroblasts. |
1991 |
Transplant. Proc. |
pmid:1721292
|
Schreiber SL et al. |
Immunophilin-ligand complexes as probes of intracellular signaling pathways. |
1991 |
Transplant. Proc. |
pmid:1721293
|
Ullman KS et al. |
Site of action of cyclosporine and FK 506 in the pathways of communication between the T-lymphocyte antigen receptor and the early activation genes. |
1991 |
Transplant. Proc. |
pmid:1721294
|
Sigal NH et al. |
Is FKBP involved in the immunosuppressive and/or toxic mechanism of action of FK 506? |
1991 |
Transplant. Proc. |
pmid:1721295
|
Bierer BE et al. |
FK 506 and rapamycin: molecular probes of T-lymphocyte activation. |
1991 |
Transplant. Proc. |
pmid:1721296
|
Tanida I et al. |
Yeast cyclophilin-related gene encodes a nonessential second peptidyl-prolyl cis-trans isomerase associated with the secretory pathway. |
1991 |
Transplant. Proc. |
pmid:1721297
|
Motta I et al. |
FK 506 favors the generation of memory T cells in vitro. |
1991 |
Transplant. Proc. |
pmid:1721324
|
Nakata S et al. |
Immunosuppressive effect of FK 506 on cytotoxic T lymphocytes and delayed-type hypersensitivity in rats. |
1991 |
Transplant. Proc. |
pmid:1721325
|
Cooper MH et al. |
Evaluation of the influence of FK 506, rapamycin, and cyclosporine on processing and presentation of particulate antigen by macrophages: assessment of a drug "carry-over" effect. |
1991 |
Transplant. Proc. |
pmid:1721326
|
Didlake R and Grogan J |
Effect of FK 506 on rat leukocyte chemotaxis. |
1991 |
Transplant. Proc. |
pmid:1721327
|
Hultsch T and Hohman RJ |
Categorizing receptor-signaling pathways with FK 506 and rapamycin. |
1991 |
Transplant. Proc. |
pmid:1721328
|
Takai K et al. |
Immunosuppressive effects of FK 506 on rat lymphoid organs. |
1991 |
Transplant. Proc. |
pmid:1721329
|
Whiteside TL et al. |
Serial monitoring of immunologic function and phenotype of lymphocytes in the blood of transplanted patients randomized to cyclosporine or FK 506. |
1991 |
Transplant. Proc. |
pmid:1721356
|
Van Thiel DH et al. |
Interferon therapy of hepatitis following liver transplantation under FK 506 or cyclosporine. |
1991 |
Transplant. Proc. |
pmid:1721357
|
Armitage JM et al. |
The clinical trial of FK 506 as primary and rescue immunosuppression in adult cardiac transplantation. |
1991 |
Transplant. Proc. |
pmid:1721358
|
Armitage JM et al. |
The clinical trial of FK 506 as primary and rescue immunosuppression in pediatric cardiac transplantation. |
1991 |
Transplant. Proc. |
pmid:1721359
|
Dew MA et al. |
Quality-of-life advantages of FK 506 vs conventional immunosuppressive drug therapy in cardiac transplantation. |
1991 |
Transplant. Proc. |
pmid:1721360
|
Shapiro R et al. |
FK 506 in clinical kidney transplantation. |
1991 |
Transplant. Proc. |
pmid:1721361
|
Demetris AJ et al. |
Histopathology of human renal allograft rejection under FK 506: a comparison with cyclosporine. |
1991 |
Transplant. Proc. |
pmid:1703360
|
Thomson AW et al. |
The influence of FK 506 on the thymus: implications of drug-induced injury to thymic epithelial cells. |
1991 |
Transplant. Proc. |
pmid:1703361
|
Mieles L et al. |
Glycemia and insulin need following FK 506 rescue therapy in liver transplant recipients. |
1991 |
Transplant. Proc. |
pmid:1703362
|
Warty V et al. |
Distribution of FK 506 in plasma lipoproteins in transplant patients. |
1991 |
Transplant. Proc. |
pmid:1703363
|
Kusne S et al. |
Early infections in kidney transplant recipients under FK 506. |
1991 |
Transplant. Proc. |
pmid:1703364
|
Winkler M et al. |
Association of elevated FK 506 plasma levels with nephrotoxicity in liver-grafted patients. |
1991 |
Transplant. Proc. |
pmid:1721389
|
Schmidt RJ et al. |
Hemolytic-uremic syndrome in a renal transplant recipient on FK 506 immunosuppression. |
1991 |
Transplant. Proc. |
pmid:1721390
|
Tze WJ et al. |
Effect of FK 506 on glucose metabolism and insulin secretion in normal rats. |
1991 |
Transplant. Proc. |
pmid:1721391
|
Doi R et al. |
Mechanisms by which FK 506 affects exocrine pancreas in rats. |
1991 |
Transplant. Proc. |
pmid:1721392
|
Rilo HL et al. |
Effect of FK 506 on function of human islets of Langerhans. |
1991 |
Transplant. Proc. |
pmid:1721393
|
Carroll PB et al. |
Synexin: a target protein for toxic effects of cyclosporine and FK 506 in endocrine cells. |
1991 |
Transplant. Proc. |
pmid:1721394
|
Cooper MH et al. |
The induction of pseudo-graft-versus-host disease following syngeneic bone marrow transplantation using FK 506. |
1991 |
Transplant. Proc. |
pmid:1721419
|
Boggs S et al. |
FK 506 has no short-term effects on endogenous or exogenous myeloid reconstitution in irradiated mice. |
1991 |
Transplant. Proc. |
pmid:1721420
|
Cooper MH et al. |
Prolonged prevention of acute graft-versus-host disease after allogeneic bone marrow transplantation by donor pretreatment using FK 506. |
1991 |
Transplant. Proc. |
pmid:1721421
|
Yoshimi F et al. |
Canine total orthotopic small bowel transplantation under FK 506. |
1991 |
Transplant. Proc. |
pmid:1721422
|
Heitman J et al. |
FK 506-binding protein proline rotamase is a target for the immunosuppressive agent FK 506 in Saccharomyces cerevisiae. |
1991 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:1705713
|
Santiago SF et al. |
Effect of donor pretreatment with FK 506 upon small intestine allotransplantation in rats. |
1991 |
Transplant. Proc. |
pmid:1721423
|
Murase N et al. |
Lymphocyte traffic and graft-versus-host disease after fully allogeneic small bowel transplantation. |
1991 |
Transplant. Proc. |
pmid:1721424
|
Goebl MG |
The peptidyl-prolyl isomerase, FK506-binding protein, is most likely the 12 kd endogenous inhibitor 2 of protein kinase C. |
1991 |
Cell |
pmid:1706222
|
Langrehr JM et al. |
Indefinite small bowel allograft survival after limited immunosuppressive therapy is not due to specific hyporesponsiveness. |
1991 |
Transplant. Proc. |
pmid:1721425
|
de Paulis A et al. |
FK-506, a potent novel inhibitor of the release of proinflammatory mediators from human Fc epsilon RI+ cells. |
1991 |
J. Immunol. |
pmid:1706398
|
Griffiths EJ and Halestrap AP |
Further evidence that cyclosporin A protects mitochondria from calcium overload by inhibiting a matrix peptidyl-prolyl cis-trans isomerase. Implications for the immunosuppressive and toxic effects of cyclosporin. |
1991 |
Biochem. J. |
pmid:1706598
|
Brabletz T et al. |
The immunosuppressives FK 506 and cyclosporin A inhibit the generation of protein factors binding to the two purine boxes of the interleukin 2 enhancer. |
1991 |
Nucleic Acids Res. |
pmid:1707162
|
Abu-Elmagd K et al. |
Efficacy of FK 506 in the treatment of recalcitrant pyoderma gangrenosum. |
1991 |
Transplant. Proc. |
pmid:1721451
|
Thomson AW et al. |
Influence of FK 506 on T lymphocytes, Langerhans' cells and the expression of cytokine receptors and adhesion molecules in psoriatic skin lesions: a preliminary study. |
1991 |
Transplant. Proc. |
pmid:1721452
|
Sainsbury TS et al. |
Differential effects of FK 506 and cyclosporine on hair regrowth in the DEBR model of alopecia areata. |
1991 |
Transplant. Proc. |
pmid:1721453
|
Fujino Y et al. |
FK 506 treatment of experimental autoimmune uveoretinitis in primates. |
1991 |
Transplant. Proc. |
pmid:1721454
|
Francavilla A et al. |
Studies on mechanisms of augmentation of liver regeneration by cyclosporine and FK 506. |
1991 |
Hepatology |
pmid:1712337
|
Liversidge J et al. |
FK 506 modulates accessory cell adhesion molecule expression and inhibits CD4 lymphocyte adhesion to retinal pigment epithelial cells in vitro: implications for therapy of uveoretinitis. |
1991 |
Transplant. Proc. |
pmid:1721455
|
Aoki H |
[FK 506, a new immunosuppressant produced by a Streptomyces]. |
1991 |
Nippon Rinsho |
pmid:1712403
|
Mochizuki M et al. |
A multicenter clinical open trial of FK 506 in refractory uveitis, including Behçet's disease. Japanese FK 506 Study Group on Refractory Uveitis. |
1991 |
Transplant. Proc. |
pmid:1721456
|
Hultsch T et al. |
Immunophilin ligands demonstrate common features of signal transduction leading to exocytosis or transcription. |
1991 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:1712484
|
Miyahara H et al. |
Comparative studies of the effects of FK506 and cyclosporin A on passively transferred collagen-induced arthritis in rats. |
1991 |
Clin. Immunol. Immunopathol. |
pmid:1712688
|
McAlpine JB et al. |
Revised NMR assignments for rapamycin. |
1991 |
J. Antibiot. |
pmid:1712766
|
Banerji SS et al. |
The immunosuppressant FK-506 specifically inhibits mitogen-induced activation of the interleukin-2 promoter and the isolated enhancer elements NFIL-2A and NF-AT1. |
1991 |
Mol. Cell. Biol. |
pmid:1712901
|
Forrest MJ et al. |
FK-506 and cyclosporin A: selective inhibition of calcium ionophore-induced polymorphonuclear leukocyte degranulation. |
1991 |
Biochem. Pharmacol. |
pmid:1716098
|
DiLella AG and Craig RJ |
Exon organization of the human FKBP-12 gene: correlation with structural and functional protein domains. |
1991 |
Biochemistry |
pmid:1716149
|
McKeon F |
When worlds collide: immunosuppressants meet protein phosphatases. |
1991 |
Cell |
pmid:1716181
|
Petros AM et al. |
NMR studies of an FK-506 analogue, [U-13C]ascomycin, bound to FKBP: conformation and regions of ascomycin involved in binding. |
1991 |
J. Med. Chem. |
pmid:1716684
|
Wu J et al. |
Comparative immunoregulatory effects of rapamycin, FK 506 and cyclosporine on mitogen-induced cytokine production and lymphoproliferation. |
1991 |
Transplant. Proc. |
pmid:1703683
|
Yoshimura R et al. |
A comparative study between cyclosporine and FK 506 effects on renal microsomal P-450. |
1991 |
Transplant. Proc. |
pmid:1703686
|
Miyagawa S et al. |
Mechanism of unresponsiveness in rats induced by a short course of FK 506 or CyA. |
1991 |
Transplant. Proc. |
pmid:1703687
|
DeFranco AL |
Signal transduction. Immunosuppressants at work. |
1991 |
Nature |
pmid:1715515
|
Carroll PB et al. |
Effect of the immunosuppressant FK 506 on insulin release from adult rat islets of Langerhans. |
1991 |
Transplant. Proc. |
pmid:1703688
|
Flanagan WM et al. |
Nuclear association of a T-cell transcription factor blocked by FK-506 and cyclosporin A. |
1991 |
Nature |
pmid:1715516
|
Sakr MF et al. |
Protective effect of FK 506 against hepatic ischemia in rats. |
1991 |
Transplant. Proc. |
pmid:1703689
|
McWhinnie DL and Morris PJ |
Combination drug therapies for immunosuppression in transplantation. |
1991 |
Ann. Acad. Med. Singap. |
pmid:1724724
|
Katayama Y et al. |
Immunosuppressive effects of FK 506 and 15-deoxyspergualin in rat lung transplantation. |
1991 |
Transplant. Proc. |
pmid:1703690
|
Pourtier-Manzanedo A et al. |
FK-506 (fujimycin) reverses the multidrug resistance of tumor cells in vitro. |
1991 |
Anticancer Drugs |
pmid:1724925
|
Nakahama H et al. |
Comparative effects of cyclosporine A and FK-506 on endothelin secretion by a cultured renal cell line, LLC-PK1. |
1991 |
J. Cardiovasc. Pharmacol. |
pmid:1725322
|
Romanowski P et al. |
[Synthetic immunomodulators designed on the basis of natural products of microorganisms]. |
1991 |
Postepy Biochem. |
pmid:1725924
|