Ruff VA and Leach KL |
Direct demonstration of NFATp dephosphorylation and nuclear localization in activated HT-2 cells using a specific NFATp polyclonal antibody. |
1995 |
J. Biol. Chem. |
pmid:7545680
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Han JW et al. |
Rapamycin, wortmannin, and the methylxanthine SQ20006 inactivate p70s6k by inducing dephosphorylation of the same subset of sites. |
1995 |
J. Biol. Chem. |
pmid:7545671
|
Hattori Y and Nakanishi N |
Effects of cyclosporin A and FK506 on nitric oxide and tetrahydrobiopterin synthesis in bacterial lipopolysaccharide-treated J774 macrophages. |
1995 |
Cell. Immunol. |
pmid:7545550
|
Han CW et al. |
Differential effects of the immunosuppressants cyclosporin A, FK506 and KM2210 on cytokine gene expression. |
1995 |
Bone Marrow Transplant. |
pmid:7545487
|
Winkler M and Christians U |
A risk-benefit assessment of tacrolimus in transplantation. |
1995 |
Drug Saf |
pmid:7545405
|
Ito T et al. |
Immunosuppressive agents induce the reduction of local pancreatic blood flow. |
1995 |
Pancreas |
pmid:7545292
|
Teague S |
Lessons from molecular matchmakers. |
1995 |
Nat. Struct. Biol. |
pmid:7545076
|
Robertus J |
Structure-based drug design ten years on. |
1994 |
Nat. Struct. Biol. |
pmid:7545074
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Taler SJ et al. |
Loss of nocturnal blood pressure fall after liver transplantation during immunosuppressive therapy. |
1995 |
Am. J. Hypertens. |
pmid:7544983
|
Varela E |
[Small bowel transplantation]. |
1995 |
Acta Gastroenterol. Latinoam. |
pmid:7544939
|
Monsour HP et al. |
Renal insufficiency and hypertension as long-term complications in liver transplantation. |
1995 |
Semin. Liver Dis. |
pmid:7544917
|
Kinoshita I et al. |
Myoblast allotransplantation in primates. |
1995 |
Muscle Nerve |
pmid:7544871
|
Hibi S et al. |
Severe rhabdomyolysis associated with tacrolimus. |
1995 |
Lancet |
pmid:7544861
|
Perrot-Applanat M et al. |
The 59 kDa FK506-binding protein, a 90 kDa heat shock protein binding immunophilin (FKBP59-HBI), is associated with the nucleus, the cytoskeleton and mitotic apparatus. |
1995 |
J. Cell. Sci. |
pmid:7544801
|
Sher LS and Makowka L |
Immunosuppression: now we have choices. |
1995 |
Hepatology |
pmid:7544759
|
Takizawa H et al. |
Activated immunocompetent cells in rat colitis mucosa induced by dextran sulfate sodium and not complete but partial suppression of colitis by FK506. |
1995 |
Digestion |
pmid:7544748
|
Ingels SC et al. |
Stability of FK506 (tacrolimus) in whole-blood specimens. |
1995 |
Clin. Chem. |
pmid:7544707
|
Firdaous I et al. |
HPLC-microparticle enzyme immunoassay specific for tacrolimus in whole blood of hepatic and renal transplant patients. |
1995 |
Clin. Chem. |
pmid:7544705
|
Hoshino H et al. |
Effects of FK506 on an experimental model of colitis in rats. |
1995 |
Aliment. Pharmacol. Ther. |
pmid:7544633
|
Hayashi S et al. |
Evidence that donor pretreatment with FK506 has a synergistic effect on graft prolongation in hamster-to-rat heart xenotransplantation. |
1995 May-Jun |
J. Heart Lung Transplant. |
pmid:7544621
|
Llull R et al. |
Multilineage amplification of graft-vs-host disease-resistant chimerism following rat vascularized bone marrow allotransplantation. |
1995 |
Transplant. Proc. |
pmid:7544504
|
Murio JE et al. |
Compassionate use of FK 506 in liver transplantation. |
1995 |
Transplant. Proc. |
pmid:7544501
|
Chang HY et al. |
Asymmetric retraction of growth cone filopodia following focal inactivation of calcineurin. |
1995 |
Nature |
pmid:7544441
|
Sauer P et al. |
In patients with orthotopic liver transplantation, serum markers of cholestasis are unreliable indicators of biliary secretion. |
1995 |
J. Hepatol. |
pmid:7544368
|
Lee MJ et al. |
Combined inhibition effects of tacrolimus and methylprednisolone on in vitro human lymphocyte proliferation. |
1995 |
Immunopharmacol Immunotoxicol |
pmid:7544367
|
Sakamoto K et al. |
A new assay method for immunosuppressants with a tacrolimus (FK506)-like mode of action. |
1995 |
J. Antibiot. |
pmid:7544337
|
Rouvière-Fourmy N et al. |
1H and 15N assignment of NMR spectrum, secondary structure and global folding of the immunophilin-like domain of the 59-kDa FK506-binding protein. |
1995 |
Eur. J. Biochem. |
pmid:7544285
|
Deschler DG et al. |
Posttransplantation lymphoproliferative disorder in patients under primary tacrolimus (FK 506) immunosuppression. |
1995 |
Arch. Otolaryngol. Head Neck Surg. |
pmid:7544136
|
Lochmüller H et al. |
Immunosuppression by FK506 markedly prolongs expression of adenovirus-delivered transgene in skeletal muscles of adult dystrophic [mdx] mice. |
1995 |
Biochem. Biophys. Res. Commun. |
pmid:7544122
|
Ishikawa A et al. |
[A case of tacrolimus-induced glucose intolerance following renal allografting]. |
1995 |
Hinyokika Kiyo |
pmid:7544064
|
Muraki T et al. |
Antithrombotic effect of FK506 versus prothrombotic effect of cyclosporine in vivo. |
1995 |
Transplantation |
pmid:7544038
|
Muthukkumar S et al. |
Rapamycin, a potent immunosuppressive drug, causes programmed cell death in B lymphoma cells. |
1995 |
Transplantation |
pmid:7544036
|
Ueda M et al. |
A proposal of FK506 optimal dosing in living related liver transplantations. |
1995 |
Transplantation |
pmid:7544035
|
Minamoto A et al. |
Suppression of corneal graft rejection by subconjunctival injection of FK-506 in a rat model of penetrating keratoplasty. |
1995 |
Jpn. J. Ophthalmol. |
pmid:7543958
|
Lam E et al. |
Isolation of a cDNA encoding a novel human FK506-binding protein homolog containing leucine zipper and tetratricopeptide repeat motifs. |
1995 |
Gene |
pmid:7543869
|
Rebollo A et al. |
Differential effect of rapamycin and cyclosporin A in proliferation in a murine T cell line expressing either intermediate or high affinity receptor for IL-2. |
1995 |
Cytokine |
pmid:7543780
|
Romero DF et al. |
Rapamycin: a bone sparing immunosuppressant? |
1995 |
J. Bone Miner. Res. |
pmid:7543725
|
Dollinger MM et al. |
Tacrolimus and cardiotoxicity in adult liver transplant recipients. |
1995 |
Lancet |
pmid:7543645
|
Textor SC et al. |
Urinary endothelin and renal vasoconstriction with cyclosporine or FK506 after liver transplantation. |
1995 |
Kidney Int. |
pmid:7543625
|
Lhoëst G et al. |
The in vitro immunosuppressive activity of the C15-demethylated metabolite of FK-506 is governed by ring- and open-chain tautomerism effects. |
1995 |
J. Pharmacol. Exp. Ther. |
pmid:7543569
|
Migita K et al. |
FK506 augments activation-induced programmed cell death of T lymphocytes in vivo. |
1995 |
J. Clin. Invest. |
pmid:7543492
|
Prud'homme GJ et al. |
Effects of cyclosporin A, rapamycin, and FK520 on peripheral T-cell deletion and anergy. |
1995 |
Cell. Immunol. |
pmid:7543371
|
Griffith JP et al. |
X-ray structure of calcineurin inhibited by the immunophilin-immunosuppressant FKBP12-FK506 complex. |
1995 |
Cell |
pmid:7543369
|
Corey HE et al. |
Renal allograft rejection in children and young adults: the Banff classification. |
1995 |
Pediatr. Nephrol. |
pmid:7543274
|
Dumont FJ et al. |
Increased LFA-1-mediated homotypic cell adhesion is associated with the G1 growth arrest induced by rapamycin in a T cell lymphoma. |
1995 |
Exp. Cell Res. |
pmid:7543051
|
Sihra TS et al. |
A role for calcineurin (protein phosphatase-2B) in the regulation of glutamate release. |
1995 |
Biochem. Biophys. Res. Commun. |
pmid:7542882
|
Strumph P et al. |
The effect of FK506 on glycemic response as assessed by the hyperglycemic clamp technique. |
1995 |
Transplantation |
pmid:7542815
|
Freeman DJ et al. |
Stability of FK 506 in whole blood samples. |
1995 |
Ther Drug Monit |
pmid:7542810
|
Warty V et al. |
Tacrolimus analysis: a comparison of different methods and matrices. |
1995 |
Ther Drug Monit |
pmid:7542809
|
Su Q et al. |
Nephrotoxicity of cyclosporin A and FK506: inhibition of calcineurin phosphatase. |
1995 May-Jun |
Ren. Physiol. Biochem. |
pmid:7542793
|
Baughman G et al. |
FKBP51, a novel T-cell-specific immunophilin capable of calcineurin inhibition. |
1995 |
Mol. Cell. Biol. |
pmid:7542743
|
Garrett-Engele P et al. |
Calcineurin, the Ca2+/calmodulin-dependent protein phosphatase, is essential in yeast mutants with cell integrity defects and in mutants that lack a functional vacuolar H(+)-ATPase. |
1995 |
Mol. Cell. Biol. |
pmid:7542741
|
Canzanello VJ et al. |
Renal sodium handling with cyclosporin A and FK506 after orthotopic liver transplantation. |
1995 |
J. Am. Soc. Nephrol. |
pmid:7542491
|
Kanda T et al. |
Synergistic effects of tacrolimus and human interferon-alpha A/D in murine viral myocarditis. |
1995 |
J. Pharmacol. Exp. Ther. |
pmid:7542339
|
Okudaira H et al. |
Enhanced production and gene expression of interleukin-5 in patients with bronchial asthma: possible management of atopic diseases by down-regulation of interleukin-5 gene transcription. |
1995 May-Jun |
Int. Arch. Allergy Immunol. |
pmid:7542077
|
McDiarmid SV et al. |
The treatment of intractable rejection with tacrolimus (FK506) in pediatric liver transplant recipients. |
1995 |
J. Pediatr. Gastroenterol. Nutr. |
pmid:7541834
|
Kaufman DB et al. |
The successful use of tacrolimus (FK506) in a pancreas/kidney transplant recipient with recurrent cyclosporine-associated hemolytic uremic syndrome. |
1995 |
Transplantation |
pmid:7541579
|
Victor RG et al. |
Presynaptic modulation of cortical synaptic activity by calcineurin. |
1995 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:7541535
|
Ockenfels HM et al. |
Cyclosporin A, FK506 and dithranol after tyrosine-specific protein phosphorylation in HaCaT keratinocytes. |
1995 |
Arch. Dermatol. Res. |
pmid:7541191
|
Rao PN et al. |
Reduction of FK-506 requirements by combination with polyethylene glycol superoxide dismutase in orthotopic rat liver transplantation. |
1995 |
J. Allergy Clin. Immunol. |
pmid:7541060
|
Kawamura A and Su MS |
Interaction of FKBP12-FK506 with calcineurin A at the B subunit-binding domain. |
1995 |
J. Biol. Chem. |
pmid:7541044
|
Yang WM et al. |
Cyclophilin A and FKBP12 interact with YY1 and alter its transcriptional activity. |
1995 |
J. Biol. Chem. |
pmid:7541038
|
Madsen KL et al. |
FK506 increases permeability in rat intestine by inhibiting mitochondrial function. |
1995 |
Gastroenterology |
pmid:7540994
|
Cardenas ME et al. |
Targets of immunophilin-immunosuppressant complexes are distinct highly conserved regions of calcineurin A. |
1995 |
EMBO J. |
pmid:7540976
|
Hikita N et al. |
Effects of topical FK506 on endotoxin-induced uveitis (EIU) in the Lewis rat. |
1995 |
Curr. Eye Res. |
pmid:7540967
|
Tashiro H et al. |
Monitoring for engraftment following rat orthotopic liver transplantation by in vitro amplification of Y-chromosome gene using polymerase chain reaction. |
1995 |
Cell Transplant |
pmid:7540919
|
Mori A et al. |
IL-5 production by CD4+ T cells of asthmatic patients is suppressed by glucocorticoids and the immunosuppressants FK506 and cyclosporin A. |
1995 |
Int. Immunol. |
pmid:7540862
|
Teutsch M et al. |
Induction of CD5 on B and T cells is suppressed by cyclosporin A, FK-520 and rapamycin. |
1995 |
Int. Immunol. |
pmid:7540861
|
Horne SM and Young KD |
Escherichia coli and other species of the Enterobacteriaceae encode a protein similar to the family of Mip-like FK506-binding proteins. |
1995 |
Arch. Microbiol. |
pmid:7540828
|
Yumiba T et al. |
Immunosuppressive and diabetogenic effect of FK 506 on pancreatic islet xenotransplantation. |
1995 |
Transplant. Proc. |
pmid:7540780
|
Reichenspurner H et al. |
First experience with FK 506 for treatment of chronic pulmonary rejection. |
1995 |
Transplant. Proc. |
pmid:7540775
|
Nielsen FT et al. |
Nephrotoxicity of FK-506 in the rat. Studies on glomerular and tubular function, and on the relationship between efficacy and toxicity. |
1995 |
Nephrol. Dial. Transplant. |
pmid:7540737
|
Dhawan A et al. |
Immunosuppressive drugs and hypertrophic cardiomyopathy. |
1995 |
Lancet |
pmid:7540242
|
Natazuka T et al. |
Immunosuppressive drugs and hypertrophic cardiomyopathy. |
1995 |
Lancet |
pmid:7540241
|
Brand PL and Brus F |
Immunosuppressive drugs and hypertrophic cardiomyopathy. |
1995 |
Lancet |
pmid:7540240
|
Zweifach A and Lewis RS |
Slow calcium-dependent inactivation of depletion-activated calcium current. Store-dependent and -independent mechanisms. |
1995 |
J. Biol. Chem. |
pmid:7540169
|
Moro A et al. |
Secretion by Trypanosoma cruzi of a peptidyl-prolyl cis-trans isomerase involved in cell infection. |
1995 |
EMBO J. |
pmid:7540135
|
Bennett WM |
The nephrotoxicity of immunosuppressive drugs. |
1995 |
Clin. Nephrol. |
pmid:7540121
|
Nash RA et al. |
Tacrolimus (FK506) alone or in combination with methotrexate or methylprednisolone for the prevention of acute graft-versus-host disease after marrow transplantation from HLA-matched siblings: a single-center study. |
1995 |
Blood |
pmid:7540071
|
Fisher A et al. |
FK506 hepatotoxicity in liver allograft recipients. |
1995 |
Transplantation |
pmid:7539961
|
Tamura K et al. |
Transcriptional inhibition of insulin by FK506 and possible involvement of FK506 binding protein-12 in pancreatic beta-cell. |
1995 |
Transplantation |
pmid:7539960
|
Siekierka JJ |
Probing T-cell signal transduction pathways with the immunosuppressive drugs, FK-506 and rapamycin. |
1994 |
Immunol. Res. |
pmid:7539823
|
Hisatomi K et al. |
Changes in the mononuclear cell subpopulations of rat cardiac transplant recipients administered FK506 for the treatment of ongoing rejection. |
1995 |
Surg. Today |
pmid:7539647
|
Wakabayashi H et al. |
The effect of FK506 on warm ischemia and reperfusion injury in the rat liver. |
1994 |
Surg. Today |
pmid:7539646
|
Lemster B et al. |
Influence of FK 506 (tacrolimus) on circulating CD4+ T cells expressing CD25 and CD45RA antigens in 19 patients with chronic progressive multiple sclerosis participating in an open label drug safety trial. |
1994 |
Autoimmunity |
pmid:7539635
|
Fealy MJ et al. |
Association of down-regulation of cytokine activity with rat hind limb allograft survival. |
1995 |
Transplantation |
pmid:7539555
|
Ko S et al. |
The enhanced immunosuppressive efficacy of newly developed liposomal FK506 in canine liver transplantation. |
1995 |
Transplantation |
pmid:7539553
|
Schleibner S et al. |
FK 506 versus cyclosporin in the prevention of renal allograft rejection--European pilot study: six-week results. |
1995 |
Transpl. Int. |
pmid:7539270
|
Rodriguez Rilo HL et al. |
Rapid hair regrowth in refractory alopecia universalis associated with autoimmune disease following liver transplantation and tacrolimus (FK506) therapy. |
1995 |
Transplantation |
pmid:7539169
|
Renoir JM et al. |
Cyclosporin A potentiates the dexamethasone-induced mouse mammary tumor virus-chloramphenicol acetyltransferase activity in LMCAT cells: a possible role for different heat shock protein-binding immunophilins in glucocorticosteroid receptor-mediated gene expression. |
1995 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:7539138
|
Chen J et al. |
Identification of an 11-kDa FKBP12-rapamycin-binding domain within the 289-kDa FKBP12-rapamycin-associated protein and characterization of a critical serine residue. |
1995 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:7539137
|
Bronsther O et al. |
Liver transplantation for HBV-related disease under immunosuppression with tacrolimus: an experience with 78 consecutive cases. |
1995 |
J Okla State Med Assoc |
pmid:7539077
|
Zhao Y et al. |
Calcineurin activation protects T cells from glucocorticoid-induced apoptosis. |
1995 |
J. Immunol. |
pmid:7539018
|
Theopold U et al. |
FKBP39, a Drosophila member of a family of proteins that bind the immunosuppressive drug FK506. |
1995 |
Gene |
pmid:7538962
|
Dumont FJ et al. |
Dominant mutations confer resistance to the immunosuppressant, rapamycin, in variants of a T cell lymphoma. |
1995 |
Cell. Immunol. |
pmid:7538911
|
Motoyama K et al. |
Pretransplant intrathymic inoculation of donor antigen combined with FK506 treatment: prolongation of survival of cardiac, but not renal, allografts in rats. |
1995 Mar-Apr |
World J Surg |
pmid:7538717
|
Ueda K et al. |
Human P-glycoprotein as a multi-drug transporter analyzed by using transepithelial transport system. |
1994 |
Jpn. J. Physiol. |
pmid:7538609
|
Pearlman DA and Connelly PR |
Determination of the differential effects of hydrogen bonding and water release on the binding of FK506 to native and Tyr82-->Phe82 FKBP-12 proteins using free energy simulations. |
1995 |
J. Mol. Biol. |
pmid:7538591
|
Columbo M et al. |
Human skin mast cells express functional beta 1 integrins that mediate adhesion to extracellular matrix proteins. |
1995 |
J. Immunol. |
pmid:7538541
|
Skeen MJ and Ziegler HK |
Activation of gamma delta T cells for production of IFN-gamma is mediated by bacteria via macrophage-derived cytokines IL-1 and IL-12. |
1995 |
J. Immunol. |
pmid:7538532
|