Kuo CJ et al. |
Rapamycin selectively inhibits interleukin-2 activation of p70 S6 kinase. |
1992 |
Nature |
pmid:1614535
|
Takaya S et al. |
The adverse impact on liver transplantation of using positive cytotoxic crossmatch donors. |
1992 |
Transplantation |
pmid:1371195
|
Francavilla A et al. |
Inhibition of liver, kidney, and intestine regeneration by rapamycin. |
1992 |
Transplantation |
pmid:1371198
|
Matsukawa W et al. |
Effects of a new immunosuppressive agent, FK506, in rats with active Heymann nephritis. |
1992 |
J. Lab. Clin. Med. |
pmid:1371298
|
Sampson BA and Gotschlich EC |
Neisseria meningitidis encodes an FK506-inhibitable rotamase. |
1992 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:1371354
|
Andersson J et al. |
Effects of FK506 and cyclosporin A on cytokine production studied in vitro at a single-cell level. |
1992 |
Immunology |
pmid:1371491
|
Strasser S et al. |
Effect of FK506 on insulin secretion in normal dogs. |
1992 |
Metab. Clin. Exp. |
pmid:1371575
|
Andersson J et al. |
FK 506 and cyclosporine inhibit antigen- or mitogen-induced monokine and lymphokine production in vitro. |
1992 |
Transplant. Proc. |
pmid:1371621
|
Matsuura T et al. |
Blockade of interleukin-2 production from cloned T cells by cyclosporine and FK 506 assessed by proliferation assays in vitro. |
1992 |
Transplant. Proc. |
pmid:1371623
|
Lake JR et al. |
Maintenance immunosuppression after liver transplantation. |
1992 |
Semin. Liver Dis. |
pmid:1373916
|
Taormina D et al. |
Stability and sorption of FK 506 in 5% dextrose injection and 0.9% sodium chloride injection in glass, polyvinyl chloride, and polyolefin containers. |
1992 |
Am J Hosp Pharm |
pmid:1373936
|
Ochiai T |
[Advances in the fundamentals and therapeutic use of immunosuppressive agents]. |
1992 |
Arerugi |
pmid:1374229
|
Hung DT and Schreiber SL |
cDNA cloning of a human 25 kDa FK506 and rapamycin binding protein. |
1992 |
Biochem. Biophys. Res. Commun. |
pmid:1374240
|
Jayaraman T et al. |
FK506 binding protein associated with the calcium release channel (ryanodine receptor). |
1992 |
J. Biol. Chem. |
pmid:1374404
|
Höllsberg P et al. |
Characterization of HTLV-I in vivo infected T cell clones. IL-2-independent growth of nontransformed T cells. |
1992 |
J. Immunol. |
pmid:1374452
|
Schreiber SL and Crabtree GR |
The mechanism of action of cyclosporin A and FK506. |
1992 |
Immunol. Today |
pmid:1374612
|
Ricordi C et al. |
Effect of FK 506 on human pancreatic islets following renal subcapsular transplantation in diabetic nude mice. |
1992 |
Transplant. Proc. |
pmid:1376512
|
Hisanaga M et al. |
Successful combination therapy with FK 506 and 15-deoxyspergualin in pancreatic islet xenografting. |
1992 |
Transplant. Proc. |
pmid:1376513
|
Ogasa N et al. |
Successful transplantation of newborn rat intestine as a free graft. |
1992 |
Transplant. Proc. |
pmid:1376514
|
Graeb C et al. |
Cytoimmunologic monitoring of small bowel allograft recipients. |
1992 |
Transplant. Proc. |
pmid:1376515
|
Date K et al. |
Effect of FK 506 on graft survival in rat small intestinal allografts. |
1992 |
Transplant. Proc. |
pmid:1376516
|
Hatazawa C et al. |
Effect of FK 506 on bowel transplantation in rats. |
1992 |
Transplant. Proc. |
pmid:1376517
|
Jain A et al. |
Intravenous, oral pharmacokinetics, and oral dosing of FK 506 in small bowel transplant patients. |
1992 |
Transplant. Proc. |
pmid:1376518
|
Masutani H et al. |
Suppression of the histologic changes of GVHD by FK 506 in rat small bowel transplantation. |
1992 |
Transplant. Proc. |
pmid:1376519
|
Foor F et al. |
Calcineurin mediates inhibition by FK506 and cyclosporin of recovery from alpha-factor arrest in yeast. |
1992 |
Nature |
pmid:1281518
|
Goldfeld AE et al. |
Transcription of the tumor necrosis factor alpha gene is rapidly induced by anti-immunoglobulin and blocked by cyclosporin A and FK506 in human B cells. |
1992 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:1281550
|
Morikawa K et al. |
The distinct effects of FK506 on the activation, proliferation, and differentiation of human B lymphocytes. |
1992 |
Transplantation |
pmid:1281561
|
Moutabarrik A et al. |
FK506-induced kidney tubular cell injury. |
1992 |
Transplantation |
pmid:1281562
|
Yagihashi A et al. |
HLA matching effect in liver transplantation. |
1992 |
Transplant. Proc. |
pmid:1281569
|
Kobayashi M et al. |
Posttransplant donor-specific T-lymphocytotoxic antibody in liver transplant patients with a positive crossmatch. |
1992 |
Transplant. Proc. |
pmid:1281570
|
Lemster B et al. |
Cytokine gene expression in murine lymphocytes activated in the presence of FK 506, bredinin, mycophenolic acid, or brequinar sodium. |
1992 |
Transplant. Proc. |
pmid:1281576
|
Tze WJ et al. |
FK 506: an effective immunosuppressant for islet xenotransplantation. |
1992 |
Transplant. Proc. |
pmid:1281577
|
Kenmochi T et al. |
[The effect of FK506 on segmental pancreas allograft in mongrel dogs]. |
1992 |
Nihon Geka Gakkai Zasshi |
pmid:1378526
|
Mouzaki A et al. |
Cyclosporin A and FK506 prevent the derepression of the IL-2 gene in mitogen-induced primary T lymphocytes. |
1992 |
Cytokine |
pmid:1378764
|
Ramamoorthy S et al. |
Selective impairment of taurine transport by cyclosporin A in a human placental cell line. |
1992 |
Pediatr. Res. |
pmid:1378960
|
Armitage JM et al. |
Clinical trial of FK 506 immunosuppression in adult cardiac transplantation. |
1992 |
Ann. Thorac. Surg. |
pmid:1379032
|
Thomson AW |
The spectrum of action of new immunosuppressive drugs. |
1992 |
Clin. Exp. Immunol. |
pmid:1379130
|
Fischer G et al. |
Mip protein of Legionella pneumophila exhibits peptidyl-prolyl-cis/trans isomerase (PPlase) activity. |
1992 |
Mol. Microbiol. |
pmid:1379319
|
Rondeau E |
[Mechanism of action of the new immunosuppressants: cyclosporin A, FK 506 and rapamycin]. |
1992 |
Nephrologie |
pmid:1379348
|
Schreiber SL |
Immunophilin-sensitive protein phosphatase action in cell signaling pathways. |
1992 |
Cell |
pmid:1379518
|
Price DJ et al. |
Rapamycin-induced inhibition of the 70-kilodalton S6 protein kinase. |
1992 |
Science |
pmid:1380182
|
Granelli-Piperno A |
SRC-related proto-oncogenes and transcription factors in primary human T cells: modulation by cyclosporin A and FK506. |
1992 |
J. Autoimmun. |
pmid:1380242
|
Reem GH |
Molecular mode of action of cyclosporin and FK506 in human thymocytes. |
1992 |
J. Autoimmun. |
pmid:1380243
|
Bach JF |
Immunointervention in autoimmune diseases from cellular selectivity to autoantigen specificity. |
1992 |
J. Autoimmun. |
pmid:1380245
|
Baumann G et al. |
Molecular mechanisms of immunosuppression. |
1992 |
J. Autoimmun. |
pmid:1380246
|
Walpoth B et al. |
Assessment of new immunosuppressive drugs in a rat cardiac allograft heterotopic model. |
1992 |
Eur Surg Res |
pmid:1380460
|
Petros AM et al. |
Conformation of two non-immunosuppressive FK506 analogs when bound to FKBP by isotope-filtered NMR. |
1992 |
FEBS Lett. |
pmid:1380470
|
Van Thiel DH et al. |
FK 506 reduces the injury experienced following renal ischemia and reperfusion. |
1992 |
Ren Fail |
pmid:1380720
|
Langrehr JM et al. |
Evidence that indefinite survival of small bowel allografts achieved by a brief course of cyclosporine or FK506 is not due to systemic hyporesponsiveness. |
1992 |
Transplantation |
pmid:1384185
|
McCarthy SA et al. |
The effects of immunosuppressive drugs on the regulation of activation-induced apoptotic cell death in thymocytes. |
1992 |
Transplantation |
pmid:1384186
|
Dhar DK et al. |
The salutary effect of FK506 in ischemia-reperfusion injury of the canine liver. |
1992 |
Transplantation |
pmid:1384188
|
Ericzon BG et al. |
FK506-induced impairment of glucose metabolism in the primate--studies in pancreatic transplant recipients and in nontransplanted animals. |
1992 |
Transplantation |
pmid:1384189
|
Meiser BM et al. |
Continuous infusion of angiopeptin significantly reduces accelerated graft vessel disease induced by FK 506 in a rat heart allograft model. |
1992 |
Transplant. Proc. |
pmid:1384201
|
Wakabayashi H et al. |
Effect of FK 506 and cyclosporine A on hepatic energy status in the rat after warm ischemia, as monitored by 31P nuclear magnetic resonance spectroscopy in vivo. |
1992 |
Transplant. Proc. |
pmid:1384205
|
Griffin AD et al. |
FK 506 in canine renal transplantation. |
1992 |
Transplant. Proc. |
pmid:1384209
|
Griffiths RJ et al. |
Characterisation of passively transferred antigen arthritis induced by methylated bovine serum albumin in the rat: effect of FK 506 on arthritis development. |
1992 |
Agents Actions |
pmid:1384284
|
Mizuno K et al. |
Modulation of multidrug resistance by immunosuppressive agents: cyclosporin analogues, FK506 and mizoribine. |
1992 Jan-Feb |
Anticancer Res. |
pmid:1373592
|
Arai S et al. |
The impact of FK506 on graft coronary disease of rat cardiac allograft--a comparison with cyclosporine. |
1992 Jul-Aug |
J. Heart Lung Transplant. |
pmid:1379829
|
Fagiuoli S et al. |
FK 506: a new immunosuppressive agent for organ transplantation. Pharmacology, mechanism of action and clinical applications. |
1992 Jul-Aug |
Ital J Gastroenterol |
pmid:1381245
|
Tong J et al. |
Effect of FK-506 and cyclosporin A on in vitro CFU-GM growth in severe aplastic anemia patients. |
1992 Jul-Aug |
Haematologica |
pmid:1385279
|
Nazer H et al. |
FK 506 associated disorders in liver transplantation. |
1992 May-Jun |
J. Gastroenterol. Hepatol. |
pmid:1377038
|
Bowman H and Lennard TW |
Immunosuppressive drugs. |
1992 Nov 4-17 |
Br J Hosp Med |
pmid:1282440
|
Sattler M et al. |
Cytochrome P-450 3A enzymes are responsible for biotransformation of FK506 and rapamycin in man and rat. |
1992 Sep-Oct |
Drug Metab. Dispos. |
pmid:1385058
|
Propper DJ et al. |
Effects of the immunosuppressive macrolides rapamycin and FK 506 in high responder rats presensitized to major histocompatibility complex antigens. |
1993 |
Transplant. Proc. |
pmid:7679837
|
Stock PG et al. |
Standard sequential immunosuppression with Minnesota antilymphoblast globulin and cyclosporine vs FK 506: a comparison of early nephrotoxicity. |
1993 |
Transplant. Proc. |
pmid:7679838
|
Tabasco-Minguillan J et al. |
Long-term insulin requirement after liver transplantation with FK 506 in American veterans. |
1993 |
Transplant. Proc. |
pmid:7679839
|
Krentz AJ et al. |
Metabolic effects of cyclosporin A and FK 506 in liver transplant recipients. |
1993 |
Diabetes |
pmid:7694879
|
Jayaraman T and Marks AR |
Rapamycin-FKBP12 blocks proliferation, induces differentiation, and inhibits cdc2 kinase activity in a myogenic cell line. |
1993 |
J. Biol. Chem. |
pmid:7503980
|
D'Ambrosio R et al. |
Validation and quality assurance program for monitoring tacrolimus (FK 506) concentrations in plasma and whole blood. |
1993 |
Ther Drug Monit |
pmid:7504339
|
Dutz JP et al. |
A role for calcineurin in degranulation of murine cytotoxic T lymphocytes. |
1993 |
J. Immunol. |
pmid:7681074
|
Takeguchi N et al. |
Inhibition of the multidrug efflux pump in isolated hepatocyte couplets by immunosuppressants FK506 and cyclosporine. |
1993 |
Transplantation |
pmid:7681229
|
Valdivia LA et al. |
Successful hamster-to-rat liver xenotransplantation under FK506 immunosuppression induces unresponsiveness to hamster heart and skin. |
1993 |
Transplantation |
pmid:7681230
|
Fujimura A et al. |
Chronopharmacokinetic study of a new immunosuppressive agent, FK 506, in mice. |
1993 |
Jpn. J. Pharmacol. |
pmid:7681489
|
Peters DH et al. |
Tacrolimus. A review of its pharmacology, and therapeutic potential in hepatic and renal transplantation. |
1993 |
Drugs |
pmid:7506654
|
Mühl H et al. |
Cyclosporin derivatives inhibit interleukin 1 beta induction of nitric oxide synthase in renal mesangial cells. |
1993 |
Eur. J. Pharmacol. |
pmid:7506668
|
Nagata K et al. |
Failure of FK-506, a new immunosuppressant, to prevent cerebral vasospasm in a canine two-hemorrhage model. |
1993 |
J. Neurosurg. |
pmid:7692019
|
Lhoëst G et al. |
Isolation and identification by FAB mass spectrometry and NMR spectroscopy of a demethylated metabolite of FK506 from erythromycin-induced rabbit liver microsomes. |
1993 |
Pharm Acta Helv |
pmid:7692454
|
Izumi S and Okuhara M |
[FK506 and kifunensine, new immunomodulators of microbial origin]. |
1993 |
Tanpakushitsu Kakusan Koso |
pmid:7692469
|
Yatscoff RW et al. |
Comparison of the effect of rapamycin and FK506 on release of prostacyclin and endothelin in vitro. |
1993 |
Clin. Biochem. |
pmid:7507804
|
White DJ |
Immunosuppression for heart transplantation. |
1993 |
Br. J. Biomed. Sci. |
pmid:7694717
|
Blaehr H et al. |
Acute effects of FK506 and cyclosporine A on cultured human proximal tubular cells. |
1993 |
Eur. J. Pharmacol. |
pmid:7683267
|
McDiarmid SV et al. |
Differences in oral FK506 dose requirements between adult and pediatric liver transplant patients. |
1993 |
Transplantation |
pmid:7685933
|
Moutabarrik A et al. |
Use of FK 506 in kidney transplantation. |
1993 |
Transplant. Proc. |
pmid:7685946
|
Moutabarrik A et al. |
Effect of FK 506 and cyclosporine on the expression of IL-6 and its receptor on stimulated monocytes. |
1993 |
Transplant. Proc. |
pmid:7685949
|
Takaya S et al. |
Use of prostaglandin E1 in crossmatch-negative liver transplant recipients treated with FK 506. |
1993 |
Transplant. Proc. |
pmid:7685953
|
Fenton M and Kay JE |
Thapsigargin activates lymphocytes via a different pathway from ionomycin. |
1993 |
Biochem. Soc. Trans. |
pmid:7510649
|
Lyson T et al. |
Cyclosporine- and FK506-induced sympathetic activation correlates with calcineurin-mediated inhibition of T-cell signaling. |
1993 |
Circ. Res. |
pmid:7688670
|
Morkawa K et al. |
Immunosuppressive property of bromocriptine on human B lymphocyte function in vitro. |
1993 |
Clin. Exp. Immunol. |
pmid:7688676
|
Yamaoka K et al. |
Cyclosporin A and FK506 block the negative signaling mediated by surface IgM cross-linking in normal human mature B cells. |
1993 |
Immunol. Lett. |
pmid:7688712
|
Starzl TE et al. |
Allograft and xenograft acceptance under FK-506 and other immunosuppressant treatment. |
1993 |
Ann. N. Y. Acad. Sci. |
pmid:7689809
|
Reem GH et al. |
FK-506 inhibits the IL-2-independent induction of the activation antigen CD 69. |
1993 |
Ann. N. Y. Acad. Sci. |
pmid:7689811
|
Mollison KW et al. |
Comparison of FK-506, rapamycin, ascomycin, and cyclosporine in mouse models of host-versus-graft disease and heterotopic heart transplantation. |
1993 |
Ann. N. Y. Acad. Sci. |
pmid:7689812
|
Tai PK et al. |
P59 (FK506 binding protein 59) interaction with heat shock proteins is highly conserved and may involve proteins other than steroid receptors. |
1993 |
Biochemistry |
pmid:7689858
|
Zuany-Amorim C et al. |
Characterization and pharmacological modulation of antigen-induced peritonitis in actively sensitized mice. |
1993 |
Br. J. Pharmacol. |
pmid:7694762
|
Fingar DC et al. |
Dissociation of pp70 ribosomal protein S6 kinase from insulin-stimulated glucose transport in 3T3-L1 adipocytes. |
1993 |
J. Biol. Chem. |
pmid:7679106
|
Griffiths EJ and Halestrap AP |
Protection by Cyclosporin A of ischemia/reperfusion-induced damage in isolated rat hearts. |
1993 |
J. Mol. Cell. Cardiol. |
pmid:7512654
|
McCaffrey PG et al. |
NF-ATp, a T lymphocyte DNA-binding protein that is a target for calcineurin and immunosuppressive drugs. |
1993 |
J. Biol. Chem. |
pmid:7679116
|
Armitage JM et al. |
Pediatric lung transplantation. The years 1985 to 1992 and the clinical trial of FK 506. |
1993 |
J. Thorac. Cardiovasc. Surg. |
pmid:7679172
|
Ito K and Komatsu Y |
[Drug induced hemolytic uremic syndrome]. |
1993 |
Nippon Rinsho |
pmid:7679450
|
Hirasé Y et al. |
Transplantation of long-term cryopreserved allocutaneous tissue by skin graft or microsurgical anastomosis: experimental studies in the rat. |
1993 |
Plast. Reconstr. Surg. |
pmid:7679796
|