Jorgensen WL |
Rusting of the lock and key model for protein-ligand binding. |
1991 |
Science |
pmid:1719636
|
Kobayashi N et al. |
Significance of pancreatic allograft rejection in swine abdominal organ cluster transplantation. |
1991 |
Transplant. Proc. |
pmid:1703707
|
Keenan RJ et al. |
Immunosuppressive properties of thalidomide. Inhibition of in vitro lymphocyte proliferation alone and in combination with cyclosporine or FK506. |
1991 |
Transplantation |
pmid:1719668
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Strasser S et al. |
The effect of FK 506 on canine pancreatic islet cell function in beagle dogs. |
1991 |
Transplant. Proc. |
pmid:1703709
|
Cryan J et al. |
FKBP, the binding protein for the immunosuppressive drug, FK-506, is not an inhibitor of protein kinase C activity. |
1991 |
Biochem. Biophys. Res. Commun. |
pmid:1719972
|
Ryu S and Yasunami Y |
Prevention of immune rejection in rat islet allografts by continuous SC administration of FK 506 using a mini-osmotic pump. |
1991 |
Transplant. Proc. |
pmid:1703710
|
Karlsson H et al. |
The immunosuppressive agent FK506 inhibits in vitro expression of membrane-bound and soluble interleukin-2 receptors on resting but not on activated human lymphocytes. |
1991 |
Immunol. Lett. |
pmid:1720417
|
Alejandro R et al. |
Combined liver-islet allotransplantation in man under FK 506. |
1991 |
Transplant. Proc. |
pmid:1703712
|
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FK-506 shows similar graft survival rate to cyclosporine but fewer side effects: Pitt transplant team. |
1991 |
Nephrol News Issues |
pmid:1720511
|
Ito T et al. |
The mechanism of tolerance induced by a perioperative injection of bone marrow cells and a brief course of FK 506. |
1991 |
Transplant. Proc. |
pmid:1703716
|
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The discovery of FK-506 and U.S. development. |
1991 |
Nephrol News Issues |
pmid:1720512
|
Zheng B et al. |
Effects of the new and highly active immunosuppressant, rapamycin, on lymphoid tissues and cells in vivo. |
1991 |
Transplant. Proc. |
pmid:1703717
|
Mieles L et al. |
Interaction between FK506 and clotrimazole in a liver transplant recipient. |
1991 |
Transplantation |
pmid:1721250
|
Yabuuchi H et al. |
Prominent prolongation of islet xenograft survival in combination therapy with FK 506 and 15-deoxyspergualin. |
1991 |
Transplant. Proc. |
pmid:1703718
|
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First International Congress on FK 506. August 21-24, 1991, Pittsburgh, PA. |
1991 |
Transplant. Proc. |
pmid:1721253
|
Goto T et al. |
FK 506: historical perspectives. |
1991 |
Transplant. Proc. |
pmid:1721254
|
Sumpio BE and Phan S |
Nephrotoxic potential of FK 506. |
1991 |
Transplant. Proc. |
pmid:1721278
|
Pichard L et al. |
Effect of FK 506 on human hepatic cytochromes P-450: interaction with CyA. |
1991 |
Transplant. Proc. |
pmid:1721279
|
Christians U et al. |
Interactions of FK 506 and cyclosporine metabolism. |
1991 |
Transplant. Proc. |
pmid:1721280
|
Wu YM et al. |
Interaction between FK 506 and cyclosporine in dogs. |
1991 |
Transplant. Proc. |
pmid:1721281
|
Habucky K et al. |
The pharmacodynamics of pentobarbital following FK 506 therapy. |
1991 |
Transplant. Proc. |
pmid:1721282
|
Farghali H et al. |
Effect of FK 506 chronic administration on bromosulphthalein hepatic excretion in rats. |
1991 |
Transplant. Proc. |
pmid:1721283
|
Farghali H et al. |
A biochemical and 31P-NMR investigation of the effect of FK 506 and cyclosporine pretreatment on immobilized hepatocytes perifused with ethanol. |
1991 |
Transplant. Proc. |
pmid:1721284
|
Farghali H et al. |
FK 506 modulates D-galactosamine-induced hepatitis in rats. |
1991 |
Transplant. Proc. |
pmid:1721285
|
Müller MK et al. |
Inhibition of insulin release by FK 506 and its prevention by rioprostil, a stable prostaglandin E1 analogue. |
1991 |
Transplant. Proc. |
pmid:1721286
|
Andersson J et al. |
The effects of FK 506 on cytokine production are dependent on the mode of cell activation. |
1991 |
Transplant. Proc. |
pmid:1721311
|
Wang SC et al. |
FK 506, rapamycin, and cyclosporine: effects on IL-4 and IL-10 mRNA levels in a T-helper 2 cell line. |
1991 |
Transplant. Proc. |
pmid:1721312
|
Woo J et al. |
Kinetics of early T-cell repopulation in the mouse following syngeneic bone marrow transplantation: FK 506 causes a maturational defect of CD4+ CD8- T cells. |
1991 |
Transplant. Proc. |
pmid:1721313
|
McCarthy SA et al. |
Effects of FK 506 and cyclosporine on T-cell tolerance: inhibition of a "protective" mechanism that regulates activation-induced apoptosis in developing thymocytes. |
1991 |
Transplant. Proc. |
pmid:1721314
|
Zeevi A et al. |
Comparative in vitro studies on the immunosuppressive activities of mycophenolic acid, bredinin, FK 506, cyclosporine, and rapamycin. |
1991 |
Transplant. Proc. |
pmid:1721315
|
Matsuura T et al. |
Beneficial immunosuppressive effect of combined use of FK 506 and cyclosporine assessed by proliferative responses of cloned human T cells. |
1991 |
Transplant. Proc. |
pmid:1721316
|
Jiang H et al. |
Combined immunosuppressive effect of FK 506 and other immunosuppressive agents on PHA- and CD3-stimulated human lymphocyte proliferation in vitro. |
1991 |
Transplant. Proc. |
pmid:1721317
|
Yagihashi A et al. |
The effect of FK 506 on peripheral blood T-lymphocyte subsets in orthotopic liver transplant patients. |
1991 |
Transplant. Proc. |
pmid:1721318
|
Uemoto S et al. |
Experience with FK 506 in living related donor liver transplantation. |
1991 |
Transplant. Proc. |
pmid:1721342
|
Tzakis AG et al. |
FK 506 versus cyclosporine in pediatric liver transplantation. |
1991 |
Transplant. Proc. |
pmid:1721343
|
Mieles LA et al. |
Liver transplantation of American veterans under FK 506 immunosuppression: a preliminary report. |
1991 |
Transplant. Proc. |
pmid:1721344
|
Nakazato P et al. |
Early experience with FK 506 induction immunosuppression--suggestion for using oral FK 506. |
1991 |
Transplant. Proc. |
pmid:1721345
|
Nakamura K et al. |
The lymphocytotoxic crossmatch in liver transplantation: a clinicopathologic analysis. |
1991 |
Transplant. Proc. |
pmid:1721346
|
Jain AB et al. |
Correlation of rejection episodes with FK 506 dosage, FK 506 level, and steroids following primary orthotopic liver transplant. |
1991 |
Transplant. Proc. |
pmid:1721347
|
Takaya S et al. |
Retransplantation of liver: a comparison of FK 506- and cyclosporine-treated patients. |
1991 |
Transplant. Proc. |
pmid:1721348
|
Morel P et al. |
Liver retransplantation in adults: overall results and determinant factors affecting the outcome. |
1991 |
Transplant. Proc. |
pmid:1721349
|
de Paulis A et al. |
Characterization of the anti-inflammatory effect of FK-506 on human mast cells. |
1991 |
J. Immunol. |
pmid:1721644
|
Morris SM et al. |
Disruption of renal function and gene expression by FK 506 and cyclosporine. |
1991 |
Transplant. Proc. |
pmid:1721375
|
Lagodziński Z et al. |
Effect of FK 506 on B-cell responses. |
1991 |
Transplant. Proc. |
pmid:1703359
|
Lieberman KV et al. |
FK 506 is a direct glomeruloconstrictor, as determined by electrical resistance pulse sizing (ERPS). |
1991 |
Transplant. Proc. |
pmid:1721376
|
Demetris AJ et al. |
Histopathology of human renal allograft rejection under FK 506: a comparison with cyclosporine. |
1991 |
Transplant. Proc. |
pmid:1703360
|
Ueda D et al. |
Influence of FK 506 on renal blood flow. |
1991 |
Transplant. Proc. |
pmid:1721377
|
Thomson AW et al. |
The influence of FK 506 on the thymus: implications of drug-induced injury to thymic epithelial cells. |
1991 |
Transplant. Proc. |
pmid:1703361
|
Perico N et al. |
FK 506 does not affect the glomerular filtration rate and renal plasma flow in the rat. |
1991 |
Transplant. Proc. |
pmid:1721378
|
Mieles L et al. |
Glycemia and insulin need following FK 506 rescue therapy in liver transplant recipients. |
1991 |
Transplant. Proc. |
pmid:1703362
|
Wagner K et al. |
Effect of FK 506 on excretion of urinary enzymes in rats. |
1991 |
Transplant. Proc. |
pmid:1721379
|
Warty V et al. |
Distribution of FK 506 in plasma lipoproteins in transplant patients. |
1991 |
Transplant. Proc. |
pmid:1703363
|
Prasad SJ et al. |
In vitro effects of cyclosporine and FK 506 on the renal cortex. |
1991 |
Transplant. Proc. |
pmid:1721380
|
Kusne S et al. |
Early infections in kidney transplant recipients under FK 506. |
1991 |
Transplant. Proc. |
pmid:1703364
|
Yamada K et al. |
Short-term FK 506-induced morphological changes in rat kidneys. |
1991 |
Transplant. Proc. |
pmid:1721381
|
Moutabarrik A et al. |
FK 506 mechanism of nephrotoxicity: stimulatory effect on endothelin secretion by cultured kidney cells and tubular cell toxicity in vitro. |
1991 |
Transplant. Proc. |
pmid:1721382
|
Adams CK and Famili P |
A study of the effects of the drug FK 506 on gingival tissues. |
1991 |
Transplant. Proc. |
pmid:1721405
|
Pirsch JD et al. |
Pulmonary infiltrates and eosinophilia in an FK 506 liver transplant recipient. |
1991 |
Transplant. Proc. |
pmid:1721406
|
Shinozuka H et al. |
Effect of FK 506 on experimental liver carcinogenesis. |
1991 |
Transplant. Proc. |
pmid:1721407
|
Pelekanou V et al. |
FK 506 and rapamycin do not affect platelet aggregation or mitochondrial function. |
1991 |
Transplant. Proc. |
pmid:1721408
|
Tai J et al. |
In vivo and in vitro effect of FK 506 on rat Leydig cell function. |
1991 |
Transplant. Proc. |
pmid:1721409
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Ricordi C et al. |
Human islet allotransplantation under FK 506. |
1991 |
Transplant. Proc. |
pmid:1721410
|
Tze WJ et al. |
Long-term survival of islet allografts in diabetic rats treated with FK 506. |
1991 |
Transplant. Proc. |
pmid:1721411
|
Wang X et al. |
Intraportal FK 506 improves intrahepatic islet allograft survival. |
1991 |
Transplant. Proc. |
pmid:1721412
|
Ohtsuka S et al. |
The effect of short-term FK 506 therapy on pancreas transplantation in rats. |
1991 |
Transplant. Proc. |
pmid:1721413
|
Ito T et al. |
Bone marrow cell- and FK 506-induced donor-specific unresponsiveness in rat heart allografts. |
1991 |
Transplant. Proc. |
pmid:1721437
|
DeValeria PA et al. |
FK 506 fails to reverse moderate cardiac allograft rejection in a canine heterotopic model. |
1991 |
Transplant. Proc. |
pmid:1721438
|
Jiang H et al. |
Prolonged cardiac allograft survival in sensitized rats by low-dose FK 506 in combination with splenectomy. |
1991 |
Transplant. Proc. |
pmid:1721439
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Sato K et al. |
Comparative study of FK 506, cyclosporine, and triple regimen immunosuppression with FK 506, cyclosporine, and mizoribine. |
1991 |
Transplant. Proc. |
pmid:1721440
|
Hohlfeld R |
[Current therapy of multiple sclerosis: value of cyclosporin A and FK 506]. |
1991 |
Nervenarzt |
pmid:1709725
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Katayama Y et al. |
Immunosuppressive effects of FK 506 in rat lung transplantation. |
1991 |
Transplant. Proc. |
pmid:1721441
|
Kay JE et al. |
Inhibition of T and B lymphocyte proliferation by rapamycin. |
1991 |
Immunology |
pmid:1709916
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Yokomise H et al. |
Immunosuppressive effects of FK 506 in canine lung transplantation. |
1991 |
Transplant. Proc. |
pmid:1721442
|
Ringe D |
Immunosuppression. Binding by design. |
1991 |
Nature |
pmid:1710317
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Hasegawa S et al. |
FK 506 and cyclosporine: effects and side effects in canine lung transplantation. |
1991 |
Transplant. Proc. |
pmid:1721443
|
Tropschug M and Hofmann R |
FK506 and protein kinase C. |
1991 |
Nature |
pmid:1710319
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Wada H et al. |
Dose response to FK 506 in canine lung transplantation. |
1991 |
Transplant. Proc. |
pmid:1721444
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Albers MW et al. |
Relationship of FKBP to PKCI-2. |
1991 |
Nature |
pmid:1710782
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Stevens C et al. |
The effects of immunosuppressive agents on in vitro production of human immunoglobulins. |
1991 |
Transplantation |
pmid:1710843
|
Metcalfe S and Milner J |
Evidence that FK506 and rapamycin block T cell activation at different sites relative to early reversible phosphorylation involving the protein phosphatases PP1 and PP2A. |
1991 |
Transplantation |
pmid:1710844
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Chang JY et al. |
FK506 and rapamycin: novel pharmacological probes of the immune response. |
1991 |
Trends Pharmacol. Sci. |
pmid:1710854
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Starzl TE et al. |
[Clinical experience with FK 506]. |
1991 |
Presse Med |
pmid:1722311
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Granelli-Piperno A and McHugh P |
Characterization of a protein that regulates the DNA-binding activity of NF-AT, the nuclear factor of activated T cells. |
1991 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:1722332
|
Nelson PA et al. |
cDNA encoding murine FK506-binding protein (FKBP): nucleotide and deduced amino acid sequence. |
1991 |
Gene |
pmid:1722474
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Calne RY |
Immunosuppression for organ grafting. |
1991 |
Transplant. Proc. |
pmid:1714646
|
Chen MF et al. |
The influence of FK-506 on the thymus and spleen in normal C3H/He mice: flow cytometric analysis of lymphocyte subpopulations. |
1991 |
Immunol. Lett. |
pmid:1722778
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Starzl TE et al. |
Notes on FK 506. |
1991 |
Transplant. Proc. |
pmid:1714647
|
Sakai K et al. |
The effect of a new immunosuppressive agent, FK-506, on xenogeneic neural transplantation in rodents. |
1991 |
Brain Res. |
pmid:1723023
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Haba T et al. |
Pathological and immunohistochemical examination in the rat treated with FK 506. |
1991 |
Transplant. Proc. |
pmid:1714649
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Forrest MJ et al. |
FK-506 and cyclosporin A: selective inhibition of calcium ionophore-induced polymorphonuclear leukocyte degranulation. |
1991 |
Biochem. Pharmacol. |
pmid:1716098
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Weaver JL et al. |
Comparison of the in vitro and biophysical effects of cyclosporine A, FK-506, and mycophenolic acid on human peripheral blood lymphocytes. |
1991 |
Immunopharmacol Immunotoxicol |
pmid:1723084
|
Lautenschlager I et al. |
Efficiency of FK 506 and CyA to prevent acute cellular rejection of pig liver allografts. |
1991 |
Transplant. Proc. |
pmid:1714650
|
DiLella AG and Craig RJ |
Exon organization of the human FKBP-12 gene: correlation with structural and functional protein domains. |
1991 |
Biochemistry |
pmid:1716149
|
Burres NS et al. |
Dunaimycins, a new complex of spiroketal 24-membered macrolides with immunosuppressive activity. III. Immunosuppressive activities of dunaimycins. |
1991 |
J. Antibiot. |
pmid:1723403
|
Epand RF and Epand RM |
The new potent immunosuppressant FK-506 reverses multidrug resistance in Chinese hamster ovary cells. |
1991 |
Anticancer Drug Des. |
pmid:1714737
|
McKeon F |
When worlds collide: immunosuppressants meet protein phosphatases. |
1991 |
Cell |
pmid:1716181
|
Christians U et al. |
Isolation of an immunosuppressive metabolite of FK506 generated by human microsome preparations. |
1991 |
Clin. Biochem. |
pmid:1714802
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Petros AM et al. |
NMR studies of an FK-506 analogue, [U-13C]ascomycin, bound to FKBP: conformation and regions of ascomycin involved in binding. |
1991 |
J. Med. Chem. |
pmid:1716684
|
Turka LA and Thompson CB |
Structure-function relationship of immunosuppressive drugs: a cautionary tale. |
1991 |
Hepatology |
pmid:1714876
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Brizuela L et al. |
Antifungal properties of the immunosuppressant FK-506: identification of an FK-506-responsive yeast gene distinct from FKB1. |
1991 |
Mol. Cell. Biol. |
pmid:1715022
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