tacrolimus

Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.

Cross Reference

Introduction

To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with tacrolimus?

tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with tacrolimus

MeSH term MeSH ID Detail
Denys-Drash Syndrome D030321 1 associated lipids
Hypophosphatemia D017674 1 associated lipids
Moyamoya Disease D009072 1 associated lipids
Latent Tuberculosis D055985 1 associated lipids
Leukoplakia D007971 1 associated lipids
Oculomotor Nerve Diseases D015840 1 associated lipids
Scorpion Stings D065008 1 associated lipids
Esophageal Perforation D004939 1 associated lipids
Mediastinitis D008480 2 associated lipids
Coproporphyria, Hereditary D046349 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with tacrolimus

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with tacrolimus?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with tacrolimus?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with tacrolimus?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with tacrolimus?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with tacrolimus?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with tacrolimus

Download all related citations
Per page 10 20 50 100 | Total 15051
Authors Title Published Journal PubMed Link
Bunnapradist S et al. LCPT once-daily extended-release tacrolimus tablets versus twice-daily capsules: a pooled analysis of two phase 3 trials in important de novo and stable kidney transplant recipient subgroups. 2016 Transpl. Int. pmid:26953629
Gokhale NS Systematic approach to managing vernal keratoconjunctivitis in clinical practice: Severity grading system and a treatment algorithm. 2016 Indian J Ophthalmol pmid:27050351
Raschzok N et al. The impact of directly acting antivirals on the enzymatic liver function of liver transplant recipients with recurrent hepatitis C. 2016 Transpl Infect Dis pmid:27632190
Nakamura H et al. Usefulness of tacrolimus for refractory adult-onset still's disease: Report of six cases. 2016 Mod Rheumatol pmid:25036233
Högerle BA et al. Challenging immunosuppression treatment in lung transplant recipients with kidney failure. 2016 Transpl. Immunol. pmid:26892232
Kimura H et al. Has widespread use of biologic and immunosuppressant therapy for ulcerative colitis affected surgical trends? Results of a questionnaire survey of surgical institutions in Japan. 2016 Surg. Today pmid:26467558
Törlén J et al. A prospective randomized trial comparing cyclosporine/methotrexate and tacrolimus/sirolimus as graft-versus-host disease prophylaxis after allogeneic hematopoietic stem cell transplantation. 2016 Haematologica pmid:27662016
Gaballa S et al. Results of a 2-arm, phase 2 clinical trial using post-transplantation cyclophosphamide for the prevention of graft-versus-host disease in haploidentical donor and mismatched unrelated donor hematopoietic stem cell transplantation. 2016 Cancer pmid:27404668
Chang KT et al. Tacrolimus suppresses atopic dermatitis-associated cytokines and chemokines in monocytes. 2016 J Microbiol Immunol Infect pmid:25315214
Brooks E et al. Population Pharmacokinetic Modelling and Bayesian Estimation of Tacrolimus Exposure: Is this Clinically Useful for Dosage Prediction Yet? 2016 Clin Pharmacokinet pmid:27138787
Nuki Y et al. Comparison of the therapeutic efficacy and safety between tacrolimus and infliximab for moderate-to-severe ulcerative colitis: a single center experience. 2016 Scand. J. Gastroenterol. pmid:26818468
Jin H et al. Clinical study of double dose of valsartan combined with tacrolimus in treatment of diabetic nephropathy. 2016 Eur Rev Med Pharmacol Sci pmid:26813471
Sawada T et al. Experimental Studies on Protective Effects of FK506 Against Hepatic Ischemia-Reperfusion Injury. 2016 J. Med. Invest. pmid:27644569
Yoshida T et al. Oral tacrolimus oil formulations for enhanced lymphatic delivery and efficient inhibition of T-cell's interleukin-2 production. 2016 Eur J Pharm Biopharm pmid:26748381
Muñoz Gómez MM et al. [Tacrolimus-induced gynecomastia in a patient with polymyositis]. 2016 Med Clin (Barc) pmid:26678165
Ferjani H et al. Protective effect of mycophenolate mofetil against nephrotoxicity and hepatotoxicity induced by tacrolimus in Wistar rats. 2016 J. Physiol. Biochem. pmid:26746208
Vasu S et al. Granulocyte Colony-Stimulating Factor-Mobilized Allografts Contain Activated Immune Cell Subsets Associated with Risk of Acute and Chronic Graft-versus-Host Disease. 2016 Biol. Blood Marrow Transplant. pmid:26743340
Pouché L et al. A candidate gene approach of the calcineurin pathway to identify variants associated with clinical outcomes in renal transplantation. 2016 Pharmacogenomics pmid:26894651
Rahnama-Moghadam S et al. Vesicular eruption in a 2-year-old boy. 2016 J Fam Pract pmid:27565104
Haasova M et al. Immunosuppressive therapy for kidney transplantation in children and adolescents: systematic review and economic evaluation. 2016 Health Technol Assess pmid:27557331
Ishiwata Y et al. Effects of Miconazole Oral Gel on Blood Concentrations of Tacrolimus and Cyclosporine: A Retrospective Observational Study. 2016 Ther Drug Monit pmid:27559841
Lee C et al. Treatment of bleomycin-induced pulmonary fibrosis by inhaled tacrolimus-loaded chitosan-coated poly(lactic-co-glycolic acid) nanoparticles. 2016 Biomed. Pharmacother. pmid:26898446
Griffin SP and Nelson JE Impact of a Clinical Solid Organ Transplant Pharmacist on Tacrolimus Nephrotoxicity, Therapeutic Drug Monitoring, and Institutional Revenue Generation in Adult Kidney Transplant Recipients. 2016 Prog Transplant pmid:27628498
Bargnoux AS et al. Evaluation of the New Siemens Tacrolimus Assay on the Dimension EXL Integrated Chemistry System Analyzer: Comparison With an Ultra-Performance Liquid Chromatography-Tandem Mass Spectrometry Method. 2016 Ther Drug Monit pmid:27494947
Faraj W et al. Osteoporosis in Pediatric Liver Transplantation. 2016 Prog Transplant pmid:27555069
Arai K et al. A Case Report of Drug-Induced Thrombocytopenia after Living Donor Liver Transplantation. 2016 Kobe J Med Sci pmid:27492209
Woolner K and Sauder M Periorbital erythema following alcohol ingestion during treatment with topical tacrolimus. 2016 CMAJ pmid:26598374
Yoshida S et al. Treatment with DHA/EPA ameliorates atopic dermatitis-like skin disease by blocking LTB4 production. 2016 J. Med. Invest. pmid:27644556
Zmonarski SC et al. Lowering of Messenger Ribonucleic Acid Toll-Like Receptors 2-4,9 in Peripheral Blood Mononuclear Cells in Kidney Allograft Recipients, Relationships With Immunosuppressive Treatment, and Delayed Graft Function Occurrence. 2016 Transplant. Proc. pmid:27496439
Ashizuka S et al. Adrenomedullin Therapy in Patients with Refractory Ulcerative Colitis: A Case Series. 2016 Dig. Dis. Sci. pmid:26470867
García-Delgado R et al. Systemic Absorption of Topical Tacrolimus in Metastatic Crohn Disease With Skin Ulcers. 2016 Actas Dermosifiliogr pmid:27372545
Gray JM and Ameduri RK Tacrolimus-associated hemolytic uremic syndrome in a pediatric heart transplant recipient. 2016 Pediatr Transplant pmid:27371345
Watanabe R et al. Successful multi-target therapy using corticosteroid, tacrolimus, cyclophosphamide, and rituximab for rapidly progressive interstitial lung disease in a patient with clinically amyopathic dermatomyositis. 2016 Mod Rheumatol pmid:25698368
Vignali D et al. IL-7 Mediated Homeostatic Expansion of Human CD4+CD25+FOXP3+ Regulatory T Cells After Depletion With Anti-CD25 Monoclonal Antibody. 2016 Transplantation pmid:27306531
Saitman A et al. Evaluation of the Waters MassTrak LC-MS/MS Assay for Tacrolimus and a Comparison to the Abbott Architect Immunoassay. 2016 Ther Drug Monit pmid:26473523
Tremblay S et al. Absence of the Effect of Pretransplant Body Mass Index on Post Kidney Transplant Outcomes. 2016 Prog Transplant pmid:27207408
Sharma A et al. Perioperative Desensitization Improves Outcomes Among Crossmatch Positive Recipients of Deceased Donor Renal Transplants. 2016 Prog Transplant pmid:27207404
Menninga NJ et al. Restless Legs Syndrome Following Lung Transplantation: Prevalence and Relationship With Tacrolimus Exposure. 2016 Prog Transplant pmid:27207403
Badri PS et al. Pharmacokinetics of Tacrolimus and Cyclosporine in Liver Transplant Recipients Receiving 3 Direct-Acting Antivirals as Treatment for Hepatitis C Infection. 2016 Ther Drug Monit pmid:27310199
Nankivell BJ et al. Calcineurin Inhibitor Nephrotoxicity Through the Lens of Longitudinal Histology: Comparison of Cyclosporine and Tacrolimus Eras. 2016 Transplantation pmid:27306529
Reeves TM et al. Targeting Kv1.3 channels to reduce white matter pathology after traumatic brain injury. 2016 Exp. Neurol. pmid:27302680
Pirmez R et al. Acne keloidalis nuchae in renal transplant patients receiving tacrolimus and sirolimus. 2016 Australas. J. Dermatol. pmid:27124649
Matsukawa T et al. Reduced-dose methotrexate in combination with tacrolimus was associated with rapid engraftment and recovery from oral mucositis without affecting the incidence of GVHD. 2016 Int. J. Hematol. pmid:27119977
Ruangkanchanasetr P et al. Beta Cell Function and Insulin Resistance After Conversion from Tacrolimus Twice-Daily to Extended-Release Tacrolimus Once-Daily in Stable Renal Transplant Recipients. 2016 Ann. Transplant. pmid:27980321
Cai SC et al. Topical calcineurin inhibitors in eczema and cancer association: A cohort study. 2016 J Dermatolog Treat pmid:27049893
Aldoss I et al. Cytogenetics Does Not Impact Outcomes in Adult Patients with Acute Lymphoblastic Leukemia Undergoing Allogeneic Hematopoietic Cell Transplantation. 2016 Biol. Blood Marrow Transplant. pmid:27044907
Yamamoto T et al. Editorial: tacrolimus vs. anti-tumour necrosis factor agents for moderately to severely active ulcerative colitis--authors' reply. 2016 Aliment. Pharmacol. Ther. pmid:27040167
Imamura CK et al. Impact of cytochrome P450 2C19 polymorphisms on the pharmacokinetics of tacrolimus when coadministered with voriconazole. 2016 J Clin Pharmacol pmid:26239045
Albano L et al. Dosing of Enteric-Coated Mycophenolate Sodium Under Routine Conditions: An Observational, Multicenter Study in Kidney Transplantation. 2016 Ann. Transplant. pmid:27122116
Gu C et al. Triptolide Reduces the Required Dose of Tacrolimus by Attenuating Inflammation, Enhancing Immunosuppression, and Increasing Donor Chimerism in a Heterotopic Hindlimb Transplantation Model. 2016 Plast. Reconstr. Surg. pmid:27879593