tacrolimus

Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.

Cross Reference

Introduction

To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with tacrolimus?

tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with tacrolimus

MeSH term MeSH ID Detail
Denys-Drash Syndrome D030321 1 associated lipids
Hypophosphatemia D017674 1 associated lipids
Moyamoya Disease D009072 1 associated lipids
Latent Tuberculosis D055985 1 associated lipids
Leukoplakia D007971 1 associated lipids
Oculomotor Nerve Diseases D015840 1 associated lipids
Scorpion Stings D065008 1 associated lipids
Esophageal Perforation D004939 1 associated lipids
Mediastinitis D008480 2 associated lipids
Coproporphyria, Hereditary D046349 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with tacrolimus

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with tacrolimus?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with tacrolimus?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with tacrolimus?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with tacrolimus?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with tacrolimus?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with tacrolimus

Download all related citations
Per page 10 20 50 100 | Total 15051
Authors Title Published Journal PubMed Link
Mercuri A et al. In vitro and in silico characterisation of Tacrolimus released under biorelevant conditions. 2016 Int J Pharm pmid:27737809
Ochi H et al. Notalgia paresthetica: treatment with topical tacrolimus. 2016 J Eur Acad Dermatol Venereol pmid:25388817
Muduma G et al. Systematic Review and Meta-Analysis of Tacrolimus versus Ciclosporin as Primary Immunosuppression After Liver Transplant. 2016 PLoS ONE pmid:27812112
Ferjani H et al. Combination of tacrolimus and mycophenolate mofetil induces oxidative stress and genotoxicity in spleen and bone marrow of Wistar rats. 2016 Mutat. Res. pmid:27776691
Deng S et al. Mechanism of tacrolimus-induced chronic renal fibrosis following transplantation is regulated by ox-LDL and its receptor, LOX-1. 2016 Mol Med Rep pmid:27633115
Chen YF et al. Tacrolimus inhibits vasoconstriction by increasing Ca(2+) sparks in rat aorta. 2016 J. Huazhong Univ. Sci. Technol. Med. Sci. pmid:26838733
Novosel MK and Bistrup C Discontinuation of steroids in ABO-incompatible renal transplantation. 2016 Transpl. Int. pmid:26706618
Witt LJ et al. Benefit of adjunctive tacrolimus in connective tissue disease-interstitial lung disease. 2016 Pulm Pharmacol Ther pmid:26762710
Dayal S et al. Treatment of Childhood Vitiligo Using Tacrolimus Ointment with Narrowband Ultraviolet B Phototherapy. 2016 Pediatr Dermatol pmid:27699846
Bakardzhiev I et al. Unilateral unique Lupus tumidus: pathogenetic mystery and diagnostic problem. 2016 Wien Med Wochenschr pmid:26762262
Jones-Hughes T et al. Immunosuppressive therapy for kidney transplantation in adults: a systematic review and economic model. 2016 Health Technol Assess pmid:27578428
Saito S et al. Role of Paternal Antigen-Specific Treg Cells in Successful Implantation. 2016 Am. J. Reprod. Immunol. pmid:26706630
Kravljaca M et al. The importance of MDR1 gene polymorphisms for tacrolimus dosage. 2016 Eur J Pharm Sci pmid:26705892
Georgiou GK et al. Calcineurin inhibitors and male fertility after renal transplantation - a review. 2016 Andrologia pmid:26341518
Herden U et al. Early Initiation of Everolimus After Liver Transplantation: A Single-Center Experience. 2016 Ann. Transplant. pmid:26842532
Yamaguchi Y et al. Plasma cell cheilitis successfully treated with topical calcineurin inhibitors. 2016 Eur J Dermatol pmid:27502182
Early CR et al. Effect of metronidazole use on tacrolimus concentrations in transplant patients treated for Clostridium difficile. 2016 Transpl Infect Dis pmid:27501504
Uemoto S et al. Advantage of tacrolimus/mycophenolate mofetil regimen for cytotoxic T cell-mediated defence and its inhibition by additive steroid administration in high-risk liver transplant recipients. 2016 Clin. Exp. Immunol. pmid:26560892
Niioka T et al. Influence of everolimus on the pharmacokinetics of tacrolimus in Japanese renal transplant patients. 2016 Int. J. Urol. pmid:26990259
Shijo T et al. A mismatch between MRI lesions and SPECT hypoperfusion in tacrolimus-related encephalopathy. 2016 J. Neurol. Sci. pmid:27423609
Chen Y et al. Clinicopathological features and prognosis of Kimura's disease with renal involvement in Chinese patients. 2016 Clin. Nephrol. pmid:27142199
Hermans C et al. Atypical discrete papular lichen myxedematosus associated with monoclonal gammopathy: report of four cases and review of the literature. 2016 J Eur Acad Dermatol Venereol pmid:27422288
Limsrichamrern S et al. Correlation of Hematocrit and Tacrolimus Level in Liver Transplant Recipients. 2016 Transplant. Proc. pmid:27320581
Kim JD et al. Single-Center Experience of ABO-Incompatible Living-Donor Liver Transplantation With a New Simplified Intravenous Immunoglobulin Protocol: A Propensity Score-Matching Analysis. 2016 Transplant. Proc. pmid:27320573
Kato H et al. Long-Term Influence of CYP3A5 Gene Polymorphism on Pharmacokinetics of Tacrolimus and Patient Outcome After Living Donor Liver Transplantation. 2016 Transplant. Proc. pmid:27320564
Federico S et al. Sublingual administration improves systemic exposure of tacrolimus in kidney transplant recipients: comparison with oral administration. 2016 Eur. J. Clin. Invest. pmid:27240092
Lazelle RA et al. Renal Deletion of 12 kDa FK506-Binding Protein Attenuates Tacrolimus-Induced Hypertension. 2016 J. Am. Soc. Nephrol. pmid:26432904
Jovanović M and Golušin Z Nonsteroidal Topical Immunomodulators in Allergology and Dermatology. 2016 Biomed Res Int pmid:27144167
Shin J et al. Prolyl hydroxylase domain 2 deficiency promotes skeletal muscle fiber-type transition via a calcineurin/NFATc1-dependent pathway. 2016 Skelet Muscle pmid:26949511
Han SS et al. Monitoring the Intracellular Tacrolimus Concentration in Kidney Transplant Recipients with Stable Graft Function. 2016 PLoS ONE pmid:27082871
Bianic F et al. Cost-effectiveness of everolimus plus reduced tacrolimus in de novo liver-recipients in the Italian setting. 2016 J Med Econ pmid:27081739
Gambarino S et al. Human Cytomegalovirus Impact on mir-146a Expression Levels in Kidney Transplant Patients. 2016 Viral Immunol. pmid:27077822
Mettang T Uremic Itch Management. 2016 Curr. Probl. Dermatol. pmid:27578082
Mok CC et al. Tacrolimus versus mycophenolate mofetil for induction therapy of lupus nephritis: a randomised controlled trial and long-term follow-up. 2016 Ann. Rheum. Dis. pmid:25550339
Suarez Benjumea A et al. Hepatitis C Virus in Kidney Transplant Recipients: A Problem on the Path to Eradication. 2016 Transplant. Proc. pmid:27932111
Xie L et al. Pretransplantation Risk Factors Associated With New-onset Diabetes After Living-donor Kidney Transplantation. 2016 Transplant. Proc. pmid:27931572
Awdishu L and Joy MS Role of Pharmacogenomics in Kidney Disease and Injury. 2016 Adv Chronic Kidney Dis pmid:26979149
Song GW et al. A Pilot Study of the Pharmacokinetics of the Modified-Release Once-Daily Tacrolimus Formulation Administered to Living-Donor Liver Transplant Recipients. 2016 Exp Clin Transplant pmid:26976646
Stockwell J et al. Protein phosphatase role in adenosine A1 receptor-induced AMPA receptor trafficking and rat hippocampal neuronal damage in hypoxia/reperfusion injury. 2016 Neuropharmacology pmid:26626486
Garcia C et al. Collaborative Brazilian Pediatric Renal Transplant Registry (CoBrazPed-RTx): A Report From 2004 to 2013. 2015 Transplant. Proc. pmid:26036492
Wang L et al. Benefits of minimizing immunosuppressive dosage according to cytochrome P450 3A5 genotype in liver transplant patients: findings from a single-center study. 2015 Genet. Mol. Res. pmid:25966085
Antonini TM et al. Therapy with boceprevir or telaprevir in HIV/hepatitis C virus co-infected patients to treat recurrence of hepatitis C virus infection after liver transplantation. 2015 AIDS pmid:25387314
Robertsen I et al. Use of generic tacrolimus in elderly renal transplant recipients: precaution is needed. 2015 Transplantation pmid:25148382
Wang L et al. Gq signaling causes glomerular injury by activating TRPC6. 2015 J. Clin. Invest. pmid:25844902
Plischke M et al. Late Conversion of Kidney Transplant Recipients from Ciclosporin to Tacrolimus Improves Graft Function: Results from a Randomized Controlled Trial. 2015 PLoS ONE pmid:26270340
Morales E et al. A case of thrombotic micro-angiopathy after heart transplantation successfully treated with eculizumab. 2015 Transpl. Int. pmid:25712140
Jia N et al. Collapsing focal segmental glomerulosclerosis following long-term treatment with oral ibandronate: case report and review of literature. 2015 BMC Cancer pmid:26197890
Ayala E et al. Myeloablative intravenous pharmacokinetically targeted busulfan plus fludarabine as conditioning for allogeneic hematopoietic cell transplantation in patients with non-Hodgkin lymphoma. 2015 Clin Lymphoma Myeloma Leuk pmid:25659459
Polańska A et al. Monitoring of therapy in atopic dermatitis--observations with the use of high-frequency ultrasonography. 2015 Skin Res Technol pmid:24894324
Urquhart BL and Knauer MJ Dried blood spots for therapeutic drug monitoring of tacrolimus and sirolimus in pediatric patients. 2015 Pediatr Transplant pmid:25546506