MeSH term | MeSH ID | Detail |
---|---|---|
Retrognathia | D063173 | 1 associated lipids |
Drug-Related Side Effects and Adverse Reactions | D064420 | 3 associated lipids |
Scorpion Stings | D065008 | 1 associated lipids |
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with tacrolimus
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Pompeo A et al. | Cyclosporin A, but not FK506, increases arachidonic acid release and inhibits proliferation of pituitary corticotrope tumor cells. | 1999 | Life Sci. | pmid:10096434 |
Kenyon NS et al. | Islet transplantation: present and future perspectives. | 1998 | Diabetes Metab Rev | pmid:10095999 |
Nakahama H et al. | Effect of FK 506 in the treatment of autoimmune glomerulonephritis in Brown Norway rats. | 1999 | Nephron | pmid:10095178 |
Kimura T et al. | N-glycosylation is involved in the sensitivity of Saccharomyces cerevisiae to HM-1 killer toxin secreted from Hansenula mrakii IFO 0895. | 1999 | Appl. Microbiol. Biotechnol. | pmid:10091323 |
Crabtree GR | Generic signals and specific outcomes: signaling through Ca2+, calcineurin, and NF-AT. | 1999 | Cell | pmid:10089876 |
Liang J et al. | Refined structure of the FKBP12-rapamycin-FRB ternary complex at 2.2 A resolution. | 1999 | Acta Crystallogr. D Biol. Crystallogr. | pmid:10089303 |
Trimbur GM et al. | Cloning, sequencing, and nucleolar targeting of the basal-body-binding nucleolar protein BN46/51. | 1999 | J. Cell. Sci. | pmid:10085251 |
Yura H et al. | Synthesis and pharmacokinetics of a novel macromolecular prodrug of Tacrolimus (FK506), FK506-dextran conjugate. | 1999 | J Control Release | pmid:10084872 |
Webber SA | 15 years of pediatric heart transplantation at the University of Pittsburgh: lessons learned and future prospects. | 1997 | Pediatr Transplant | pmid:10084782 |
Atkison P et al. | Small bowel transplantation in children. | 1997 | Pediatr Transplant | pmid:10084770 |